Clinical trials: Depressive State
Depression, Anxiety
Physical Exercise for Treatment of Depression and Anxiety - RCT
In a 12 week randomly controlled open trial 102 participants with symptoms of depression and/or anxiety will be exposed to either aerobic high intensity training (HIT) or relaxation therapy.
- Trial name
- FYPO (NCT04714528)
- Testing
- Physical Exercise, Relaxation Therapy
- Where
- Sweden
- Volunteers
- 87 people
- Sponsor
- Region Örebro County
Multiple Sclerosis
Depression and Fatigue in MS Patients Treated With Betaferon.
This study aims to evaluate the occurence and severity of fatigue and depression in multiple sclerosis patients and the impact of Betaferon treatment on symptoms alterations.
- Trial name
- FADO (NCT01354665)
- Testing
- Interferon beta-1b (Betaferon, BAY86-5046)
- Where
- Poland
- Volunteers
- 567 people
- Sponsor
- Bayer
Depression, Anxiety
Effects of MSC Intervention on the Dyadic Mental Health of Lung Cancer Patients and Their Caregivers
The incidence and mortality of lung cancer ranks first among cancers in the world, and the five-year survival rate of lung cancer patients is only 15% to 30%.
- Trial name
- NCT04795700
- Testing
- MSC intervention
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Central South University
Cancer
Implementation and Evaluation of Dignity Therapy in Denmark
The purpose of the study is to investigate whether Danish patients with incurable cancer have a need of, interest in and benefit from Dignity Therapy.
- Trial name
- DignityDK (NCT01507571)
- Testing
- Dignity Therapy
- Where
- 2 sites in Denmark
- Volunteers
- 80 people
- Sponsor
- Bispebjerg Hospital
Anxiety, Depression
Stanford RAD-AT Study (Research on Anxiety and Depression - Anhedonia Treatment)
This research study is aimed at understanding behaviors and brain circuits that relate to anxiety and depression. Our goal is to learn which circuits of the brain are involved in anxiety and how these circuits might affect daily…
- Trial name
- NCT02220309
- Testing
- Pramipexole Oral Tablet
- Where
- 3 sites in United States
- Volunteers
- 167 people
- Sponsor
- Stanford University
Left Rostromedial Prefrontal Cortex - Accelerated Intermittent Theta Burst, Left Dorsolateral Prefrontal Cortex - Accelerated Intermittent Theta Burst
Causal Role of Rostromedial Prefrontal Cortex for Positive Savoring in Depression
This is a non-invasive brain stimulation and neuroimaging study that will examine how activity in the medial prefrontal cortex influences reward processing, particularly positive savoring, in individuals with depression.
- Conditions
- Left Rostromedial Prefrontal Cortex - Accelerated Intermittent Theta Burst, Left Dorsolateral Prefrontal Cortex - Accelerated Intermittent Theta Burst, Left Primary Somatosensory Cortex - Accelerated Intermittent Theta Burst
- Trial name
- rmPFC-Savoring (NCT07467473)
- Testing
- Accelerated Intermittent Theta Burst Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Florida State University
Needs for Rehabilitation, Adult Attachment Style
The Need for Rehabilitation and the Connection With Attachment Styles Among Patients With Gynaecological Cancer
The purpose of this study is to provide new knowledge about: Integration of rehabilitation in a highly specialized gynaecological department. Development and testing of an individually adapted rehabilitation process.
- Conditions
- Needs for Rehabilitation, Adult Attachment Style, Quality of Life., Depression
- Trial name
- NCT01638741
- Testing
- Rehabilitation goals of patients with gynaecological cancer.
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Kamila Adellund Holt
Emotional Disorders, Anxiety
Unified Protocol Group Treatment in a University Outpatient Clinic
This clinical trial aims to evaluate the effectiveness and underlying processes of change of the Unified Protocol (UP) for treating emotional disorders in a university outpatient clinic.
- Conditions
- Emotional Disorders, Anxiety, Depression - Major Depressive Disorder
- Trial name
- NCT07129941
- Testing
- Unified Protocol
- Where
- Norway
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Anxiety, Depression
Transdiagnostic Treatment of Emotional Disorders for Women in a Homeless Situation
The aim of this study is to assess the effectiveness and feasibility of an adaptation of the Unified Protocol (UP) for Transdiagnostic Treatment of Emotional Disorders to women living homeless in Madrid, Spain.
- Trial name
- UPHW (NCT04392856)
- Testing
- Unified Protocol for Transdiagnostic Treatment of Emotional Disorders (UP), Same than experimental condition (UP), after it finishes
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Universidad Complutense de Madrid
Depression
A Computer-Assisted CBT Tool to Enhance Fidelity in CBOCs
Background and Significance: Mental health (MH) providers in VA Community-Based-Outpatient-Clinics (CBOCs) are often located in rural areas and isolated from educational opportunities. Almost half of Veterans now use CBOCs.
- Trial name
- NCT02488551
- Testing
- Computer-delivered CALM, Manual-delivered CALM
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Depression Disorders, Anxiety
Unified Protocol in Penitentiary Facilities
Emotional disorders (EDs), which include anxiety disorders, unipolar mood disorders, and other related conditions, exhibit a high prevalence within prison populations, significantly exceeding that of the general population.
- Conditions
- Depression Disorders, Anxiety, Mood Disorders, Emotional Disorder
- Trial name
- NCT07070531
- Testing
- Unified Protocol
- Where
- Spain
- Volunteers
- 25 people
- Sponsor
- Instituto de Investigación Sanitaria Aragón
Postpartum Urinary Incontinence, Postpartum Depression (PPD)
Prenatal Exercise Including Perineal Massage and Maternal-Neonatal Outcomes
The study is divided into three phases: Phase 1: Baseline survey to obtain an overall understanding of the current situation of voluntary participation in prenatal perineal massage.
- Conditions
- Postpartum Urinary Incontinence, Postpartum Depression (PPD), Neonatal Complications, Gestational Diabetes
- Trial name
- PEPM-RCT (NCT07314502)
- Testing
- Supervised prenatal exercise including antenatal perineal massage
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- South China Normal University
Bipolar Disorder, Mood Disorder
Evaluation of Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Mood Disorders
This study is designed to evaluate repetitive transcranial magnetic stimulation (rTMS) as a potential treatment for depression. In rTMS, a rapidly changing magnetic field passes through your scalp and skull and generates a small…
- Conditions
- Bipolar Disorder, Mood Disorder, Unipolar Depression
- Trial name
- NCT00001545
- Testing
- Magstim Super Rapid Magnetic Stimulator, Cadwell MES-10
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- National Institute of Mental Health (NIMH)
Psychological Stress, Depressive Symptoms
Effectiveness of Medicorp HO Preparatory Course
After completion of 5 years of medical school training, the next step of becoming a House Officer is said to be associated with high levels of stress.
- Conditions
- Psychological Stress, Depressive Symptoms, Anxiety State, Motivation
- Trial name
- NCT03510195
- Testing
- MEDICORP HO PREPARATORY MODULE
- Where
- Malaysia
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Perinatal Depression
Perinatal Mental Health Screening and Early Community Intervention Using Digital Clinical Pathways (MATTER Project)
The MATTER project is a digital, community-based perinatal mental health screening and early intervention program implemented in primary care and hospital settings in the Alentejo region, Portugal.
- Trial name
- MATTER (NCT07659977)
- Where
- Portugal
- Volunteers
- 1,500 people
- Sponsor
- Universidade Nova de Lisboa
Chronic Pain, Musculoskeletal Pain
Equipping Patients Using Interventions for Pain and Depression
This project is part of the NIH Helping to End Addiction Long-term (HEAL) initiative (https://heal.nih.gov/). This randomized controlled trial (RCT) is phase 2 of a two-phase, 5-year project with the overarching goal of testing a…
- Conditions
- Chronic Pain, Musculoskeletal Pain, Depression, Health Equity
- Trial name
- EQUIPD (NCT06500780)
- Testing
- Coaching and Decision Aid
- Where
- United States
- Volunteers
- 304 people
- Sponsor
- Indiana University
Comfort Theory, AI-Assisted Group Music Intervention
Applying Comfort Theory to an AI-Assisted Group Music Intervention: Psychosocial and Physiological Outcomes and Feasibility in Long-Term Care Residents.
The research design adopts a sequential two-phase framework. The study will be conducted in three residential LTC facilities located in Taichung City or Changhua County, with a total planned enrollment of 60 residents.
- Conditions
- Comfort Theory, AI-Assisted Group Music Intervention, Long-Term Care Residents, Loneliness
- Trial name
- NCT07882979
- Testing
- Group music intervention, AI-assisted monitoring system
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yu Chia Chang
Medication Adherence, Medication Compliance
Connected Healthcare for Individuals Living at Home With Chronic Conditions
Managing and taking medications as prescribed can be a difficult task. This is especially true for older adults living at home with chronic conditions while managing multiple prescribed medications.
- Conditions
- Medication Adherence, Medication Compliance, Medication Nonadherence, Hypertension
- Trial name
- NCT04339296
- Testing
- Spencer
- Where
- Canada
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Alberta Health Services, Calgary
Chronic Hepatitis c
Frequency of Anxiety and Depression in Chronic Hepatitis C Patients Recieving Direct-Acting Antiviral Agents
The primary objective of this study is to prospectively analyse psychiatric outcomes, specifically depression and anxiety in patients with hepatitis C virus infection who are initiated on DAA therapy (sofosbuvir based regimen).
- Trial name
- NCT03894696
- Testing
- Direct Acting Antivirals
- Volunteers
- 200 people
- Sponsor
- Assiut University
Anxiety Disorders and Symptoms, Depression
Positive Valence System Enhancement Treatment for Anxiety and Depression: Clinical Efficacy and Neural Changes
The proposed project aims to test the efficacy and neural correlates of a behavioral treatment program comprised of positive activity interventions in a sample of individuals seeking treatment for anxiety or depression.
- Trial name
- NCT02330627
- Testing
- Positive Valence System Treatment
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of California, San Diego
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