Clinical trials: Depressive State
Depression
A Randomized Clinical Trial for Depressed Mothers at Primary Care Level
A randomized clinical trial was carried out at primary care level in Santiago, Chile to compare a pharmacological intervention for depressed mothers controlled by phone from a central level (TM) and the usual treatment (TH) and…
- Trial name
- DMH (NCT00519051)
- Testing
- monitorized pharmacotherapy with antidepressants drugs (Fluoxetine)
- Where
- Chile
- Volunteers
- 345 people
- Sponsor
- Fondo Nacional de Desarrollo Científico y Tecnológico, Chile
Post Traumatic Stress Disorder
Early Prevention of PTSD in Patients Within One Week of Acute Physical Trauma
The objective of this study is to assess the feasibility and effectiveness of AEPET plus Resilience Based Therapy (RBT) versus RBT alone for the prevention of PTSD and depression in trauma patients.
- Trial name
- NCT02915497
- Testing
- Abbreviated Early Prolonged Exposure Therapy
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Sunnybrook Health Sciences Centre
Wheel-chair Dependent Elders
Improvement and Mechanism of Wheel-chair Music Aerobic Exercise on Depression and Insomnia Among the Elderly in Long-term Care Facilities
Investigators anticipate to develop a customized WC-MAE for the improvement of insomnia and depression in wheel-chair dependent elders, and to identify related mechanisms as biomarkers for prediction and prevention of insomnia…
- Trial name
- NCT02256020
- Testing
- Original lifestyle, Wheel-chair music aerobic exercise (WC-MAE)
- Where
- Taiwan
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Chang Bing Show Chwan Memorial Hospital
Hepatitis C, Depression
Hepatitis C Translating Initiatives for Depression Into Effective Solutions
Chronic infection with hepatitis C (CHC) is a common and expensive condition, and it disproportionately affects Veterans. Treatment with antiviral therapy reduces liver disease progression and improves health related quality of…
- Trial name
- HEPTIDES (NCT01143896)
- Testing
- Depression collaborative care model
- Where
- 4 sites in United States
- Volunteers
- 309 people
- Sponsor
- VA Office of Research and Development
Neuropathic Pain, Anxiety Disorder/Anxiety State
Predictive and Impact of Pain After 6 Months of Radiotherapy, in Head and Neck Cancer
Head and neck cancers are a source of complications and after-effects related to the disease and treatment. These cancers and their treatment alter the quality of life of patients and generate pain with physical and psychological…
- Conditions
- Neuropathic Pain, Anxiety Disorder/Anxiety State, Pain, Chronic, Alcohol Use Disorder
- Trial name
- DIP-CAOS (NCT05505188)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Caen
Post-stroke Depression
Transcranial Direct Current Stimulation on Post Stroke Depression
The aim of the research is to address the critical gap that limited number of RCTs are conducted on this topic. To further explore the efficacy of tDCs, large sample sizes, large follow up period and rigorously controlled…
- Trial name
- NCT06598670
- Testing
- tDCS, Conventional treatment
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Riphah International University
Resistant Depression, Treatment, Bipolar Depression
Efficacy and Biomarkers of Response of TBS in Treatment Resistant Depression
Theta Burst Transcranial Magnetic Stimulation (TBS) in dorsolateral prefrontal cortex (DLPFC) has shown efficacy and safety as an adjuvant strategy for resistant to treatment depression (RTD) in daily sessions during 4-6 weeks…
- Trial name
- EMTtfNI (NCT04998773)
- Testing
- Theta Burst Transcranial Magnetic Bilateral Stimulation, Theta Burst Transcranial Magnetic Unilateral Stimulation
- Where
- Spain
- Volunteers
- 96 people
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
Cesarean Section Complications
The Effect of Reiki on Cesarean During Hospitalization
To determine the effect of reiki applied to women who have been hospitalized by cesarean during the hospitalization process on anxiety, depression, comfort and breastfeeding Method: The study will be completed in a randomized…
- Trial name
- NCT06437769
- Testing
- reiki
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Stroke
Psychosocial/Behavioral Intervention in Post-Stroke Depression
The primary aim of this study is to determine the effect of a nurse-delivered psychosocial/behavioral intervention on reduction of depression in community dwelling post-stroke patients.
- Trial name
- NCT00194454
- Testing
- Modified cognitive behavioral therapy plus problem-solving, usual care
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- University of Washington
Cognition, Depression
To Enhance Cognition in Late Life Depression Using Transcranial Direct Current Stimulation
Late Life Depression (LLD) is a serious health problem which not only causes depressed mood but also results in impairments in memory and attention.
- Trial name
- NCT02212366
- Testing
- Active TDCS
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- Centre for Addiction and Mental Health
Premenstrual Syndrome, Anxiety
The Efficacy of Lavender Herbal Tea in Premenstrual Syndrome
Premenstrual syndrome (PMS) is a common but complex condition defined as a combination of emotional, psychological, and physical symptoms that occur during the luteal phase of the menstrual cycle, usually between 2 and 14 days…
- Conditions
- Premenstrual Syndrome, Anxiety, Depression, Stress
- Trial name
- NCT07737366
- Testing
- Lavender herbal tea
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sakarya University
Stigmatization, Depression
Impact of Video Presentations on Medical Students' Attitudes Toward Mental Illness
This is a randomized controlled trial examining the impact of videos on medical students' implicit and explicit attitudes and knowledge related to mental illness in Nepal.
- Conditions
- Stigmatization, Depression, Psychosis
- Trial name
- NCT03231761
- Testing
- Service user testimonial videos, mhGAP didactic video
- Where
- 2 sites in Nepal
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- George Washington University
Posttraumatic Stress Disorder, Depression
The Pitt Center for Emergency Responder Wellness
Emergency responders protect the public despite occupational hazards that threaten their mental health. The Pitt Center for Emergency Responder Wellness will be a clinical innovation hub that: 1) delivers accessible interventions…
- Conditions
- Posttraumatic Stress Disorder, Depression, Anxiety, Alcohol Use Disorder
- Trial name
- NCT05357586
- Testing
- Unified Protocol for Transdiagnostic Treatment of Emotional Disorders
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Depression
PATH 2 Purpose: Primary Care and Community-Based Prevention of Mental Disorders in Adolescents
PATH (Promoting AdolescenT Health) 2 Purpose is a two-arm comparative effectiveness research trial to that will evaluate the ability of the interventions, Competent Adulthood Transition with Cognitive-behavioral \& Interpersonal…
- Trial name
- P2P (NCT04290754)
- Testing
- CATCH-IT, TEAMS
- Where
- United States
- Volunteers
- 636 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
HIV, Major Depressive Disorder
CID 0911 - Adaptation of A Depression Treatment Intervention for HIV Patients in Cameroon
The purpose of this study is to adapt depression treatment intervention for HIV patients in Cameroon. The PI will validate a depression severity measure, adapt key elements of the intervention to the Cameroon context, train…
- Trial name
- ADEPT (NCT02156622)
- Volunteers
- 55 people
- Sponsor
- University of North Carolina, Chapel Hill
Body Image
Impact of Exposure to Images of the Idealised Physique on Body Satisfaction, Dieting Intentions and Mood in Men.
Every day, people are exposed to huge amounts of media. Research has explored the impact of viewing traditional media and advertising (such as television and magazines) on how a person thinks and feels about their body (body…
- Trial name
- NCT03991351
- Testing
- Exposure to images
- Where
- United Kingdom
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Schizophrenia, Psychosis
Minnesota Community-Based Cognitive Training in Early Psychosis
The purpose of this study is to determine whether cognitive training exercises can improve cognitive functioning in young patients with recent-onset psychosis who are being treated in community mental health settings using the…
- Conditions
- Schizophrenia, Psychosis, Schizoaffective Disorder, Schizophreniform Disorders
- Trial name
- Mini-COTES (NCT03079024)
- Testing
- Targeted Cognitive Training, General Cognitive Exercises, Coordinated Specialty Care for First Episode Psychosis
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Minnesota
Breast Cancer, Cognitive/Functional Effects
Doxorubicin and Cyclophosphamide in Treating Older Women With Stage I, Stage II, or Stage III Breast Cancer That Has Been Removed By Surgery
RATIONALE: Drugs used in chemotherapy, such as doxorubicin and cyclophosphamide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Conditions
- Breast Cancer, Cognitive/Functional Effects, Depression, Malnutrition
- Trial name
- NCT00424203
- Testing
- AC regimen, cyclophosphamide, doxorubicin hydrochloride
- Where
- 17 sites in France
- Volunteers
- 40 people
- Sponsor
- UNICANCER
Depression, Anxiety Disorders
A Feasibility Study of a Transdiagnostic Compassion Focused Therapy (CFT) Group for Older Adults
Compassion focused therapy (CFT) is a relatively new psychological therapy. Research has shown that CFT can improve psychological wellbeing and functioning in people with anxiety and depressive disorders.
- Trial name
- NCT04039542
- Testing
- Compassion focused therapy (CFT)
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- NHS Greater Glasgow and Clyde
Major Depression (in Remission)
Investigating the Mechanisms of Mindfulness-based Cognitive Therapy (MBCT)
This research will investigate the neuropsychological mechanisms underlying the eight-week Mindfulness-based Cognitive Therapy (MBCT) programme.
- Trial name
- NCT02226042
- Testing
- Mindfulness-based Cognitive Therapy
- Where
- United Kingdom
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University of Manchester
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