Clinical trials: Depressive State
Depression, Anxiety, Mental Health Issue
Clinical Outcomes of a Digital Mental Health Intervention for Moderate/Severe Depression and Anxiety
A digital mental health intervention (BetterHelp, Mountain View, CA) provides users with access to online therapy care for treatment of depression and anxiety.
- Conditions
- Depression, Anxiety, Mental Health Issue, Mental Health Wellness 2
- Trial name
- NCT07081061
- Testing
- BetterHelp
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Teladoc Health
Post-polio Syndrome, Physical Activity
Glutathione and Health With Post-Polio Syndrome
In this study, people who have symptoms of post polio will take oral glutathione supplements for three months. Their levels of fatigue, physical activity and sleep efficiency will be assessed.
- Conditions
- Post-polio Syndrome, Physical Activity, Depression, Pain
- Trial name
- NCT01402570
- Testing
- Glutathione
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Michigan
Adolescent Idiopathic Scoliosis, Respiratory Depression
Anesthetic Optimization in Scoliosis Surgery
The standard anesthetic care plan for people having adolescent idiopathic scoliosis surgery will be accompanied by a pharmacokinetic simulation of the administered drugs to suggest opportunities to adjust drug doses to achieve…
- Conditions
- Adolescent Idiopathic Scoliosis, Respiratory Depression, Postoperative Pain
- Trial name
- AIS (NCT02481570)
- Testing
- pharmacokinetic simulation
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Florida
Pediatric Cancer
Psychoeducation Intervention for Caregivers of Children With Cancer
This randomized controlled trial aims to evaluate the effectiveness of the psychoeducation intervention on anxiety, depressive symptoms, coping, and HRQoL in caregivers of children with cancer.
- Trial name
- NCT05783310
- Testing
- Psychoeducation Intervention
- Where
- 2 sites in Malawi
- Volunteers
- 118 people
- Sponsor
- Chinese University of Hong Kong
Treatment of Depression in Adults With Parkinson's Disease (PD)
Safety and Efficacy of Pimavanserin in Adults With Parkinson's Disease and Depression
The purpose of this study is to assess the efficacy of pimavanserin for the treatment of depression in adults with Parkinson's disease.
- Trial name
- NCT03482882
- Testing
- Pimavanserin
- Where
- 21 sites in United States
- Volunteers
- 47 people
- Sponsor
- ACADIA Pharmaceuticals Inc.
Depression, Anxiety
Clinical Study to Evaluate Patient Outcomes Following Pharmacogenetic Testing of Subjects Exhibiting Neuropsychiatric Disorders
The purpose of this study is to evaluate the effect of pharmacogenetic (PGx) testing on clinical outcomes in a group of subjects exhibiting neuropsychiatric disorders, such as depression and anxiety, as compared to a group of…
- Trial name
- NCT02411123
- Testing
- IDgenetix Neuropsychiatric Test Panel
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- AltheaDx
Neoplasms, Cancer
A Feasibility Study to Determine Whether the Botanical Garden Become a Region of Forest Therapy for Cancer Survivors
The forest healing system is an important topic of alternative therapy in recent years. To investigates forest therapy's effectiveness in alleviating negative emotions among post-cancer patients.
- Conditions
- Neoplasms, Cancer, Mental Health Disorder, Depression
- Trial name
- NCT06001723
- Testing
- Forest Therapy
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Taipei City Hospital
Mental Health Issue
Effects of a Brief Mindful Parenting Program for Hong Kong Chinese Impacted by Social Unrest
A four session mindful parenting workshop is designed to promote parental mental health during the social unrest in 2020. This study is conducted to investigate the outcome of the program.
- Trial name
- MPHKC (NCT04427683)
- Testing
- Brief mindful parenting program
- Where
- Hong Kong
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Depression
Treatment of Depression in Adults
This study will determine how certain features of depressed individuals affect their responses to depression treatment.
- Trial name
- NCT00073697
- Testing
- Escitalopram, Interpersonal Psychotherapy, Escitalopram plus IPT
- Where
- 2 sites in United States, Italy
- Volunteers
- 290 people
- Sponsor
- University of Pittsburgh
Depression in Adults, Anxiety
Structured Group Therapy in Reducing Depression and Anxiety in Pakistan
This study aims to assess the effectiveness of Cognitive Behavioural Therapy (CBT) and Mindfulness-Based Stress Reduction (MBSR) in group settings to reduce symptoms of depression and anxiety, enhance emotional resilience, and…
- Trial name
- NCT07239388
- Testing
- Structured group therapy
- Where
- Pakistan
- Volunteers
- 108 people
- Sponsor
- Pakistan Association of Cognitive Therapists
Depression
Treating Depression With Transcranial Direct Current Stimulation (tDCS)
The purpose of this study is to see if transcranial direct current stimulation may improve the symptoms of depression.
- Trial name
- NCT00481988
- Testing
- transcranial direct current stimulation, iomed phoresor transcranial direct current stimulation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- New York State Psychiatric Institute
Type 1 Diabetes (T1D)
Pragmatic Clinic-Based Trial of a Mindfulness Based Intervention for Mood Concerns in Youth With Type 1 Diabetes
Type 1 diabetes (T1D) is a common chronic illness among children requiring a high degree of self-management for good glycemic control.
- Trial name
- BREATHE-T1D (NCT06618027)
- Testing
- BREATHE-T1D, HealthEd-T1D
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Children's National Research Institute
Baby Massage, Postpartum Depression
The Effect of Baby Massage Training Given to Pregnant Women on Maternal Attachment and Postpartum Depression
The research to be conducted within the scope of the project will be randomized controlled, and the population of the research will be primiparous pregnant women reached through social media.
- Trial name
- NCT06136520
- Testing
- Baby massage
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Depression, Anxiety
Behavioral Activation Therapy for Medical Students With Symptoms of Depression in Two Cities of Mexico
This study evaluates the effectiveness of The Behavioral Activation Protocol, a psychological treatment for the intervention of mild to moderate depression.
- Trial name
- NCT04069182
- Testing
- Behavioral Activation Therapy
- Where
- 2 sites in Mexico
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Depression, Anxiety, Distress, Emotional
PSilocybin for psYCHological and Existential Distress in PALliative Care (PSYCHED-PAL)
The goal of this multi-centre phase I/II open-label, single-arm study is to determine the safety, feasibility, therapeutic dose, and preliminary efficacy of psilocybin microdosing to treat psychological distress among patients…
- Trial name
- NCT04754061
- Testing
- Psilocybin
- Where
- 2 sites in Canada
- Volunteers
- 20 people
- Sponsor
- Ottawa Hospital Research Institute
Hematologic Disease
Anxiety and Depression in Patients With Hematologic Malignancies
Assessment of Anxiety and Depression Status in Patients with Hematologic Malignancies
- Trial name
- NCT07883070
- Testing
- Baseline Anxiety and/or Depression
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital of Xiamen University
Dermatologic Disease, Depression
Investigating Compassion-Based Guided Self-Help for Depression in People With Skin Conditions
The study aims to explore whether an online compassion-based guided self-help intervention is perceived as acceptable to people with heterogeneous skin conditions, in terms of retention rates and explicit feedback.
- Trial name
- NCT04132973
- Testing
- Compassion for Skin Conditions
- Where
- United Kingdom
- Volunteers
- 34 people
- Sponsor
- University of Sheffield
HIV, Depression
Neighborhoods, Networks, Depression, and HIV Risk
The goal of this study is to examine how social networks, neighborhood, and depression are related to HIV risk. The intervention is designed to train individuals to cope with feelings of depression or stress as a way to reduce…
- Conditions
- HIV, Depression, Drug Use
- Trial name
- Workshop (NCT01380613)
- Testing
- Workshop, Workshop control
- Where
- United States
- Volunteers
- 965 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Depression
Pipamperone/Citalopram (PipCit)Versus Citalopram in the Treatment of Major Depressive Disorder(MDD)
The primary objective is to demonstrate whether the addition of pipamperone 5 mg twice daily (bd) to citalopram, 40 mg daily in patients suffering from MDD will improve the efficacy of citalopram 40 mg in these patients.
- Trial name
- NCT00672659
- Testing
- Citalopram + Pipamperone, Citalopram
- Where
- United Kingdom
- Volunteers
- 165 people
- Sponsor
- PharmaNeuroBoost N.V.
Changes in Brain Network Connectivity
Anesthesia and Functional Connectivity: An Analysis of fMRI Changes
Functional connectivity is defined as a correlation in neural activity between distinct regions of the brain. Several recent studies have demonstrated areas of low-frequency functional connectivity inherent to brain tissue at…
- Trial name
- NCT02196259
- Testing
- Anesthetics, Dissociative
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Michigan
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