Clinical trials: Depressive Symptomatology
Psychotic Disorders, Depressive Disorder
Genetics of Symptomatology and Treatment Response in Psychotic Major Depression
We hope to learn more about the biology of psychiatric illness with the hope of improving the diagnosis and treatment of such psychiatric conditions as major depression.
- Conditions
- Psychotic Disorders, Depressive Disorder, Depressive Disorder, Major
- Trial name
- NCT00691535
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Stanford University
Mild-to-moderate Depression, Neural Activity
Probiotics for Depressive Symptomatology and Neural Activity.
This study aims to investigate the acute and chronic effects of 16-week probiotic supplementation (Ecologic® Barrier) on depressive symptoms and neural activity in those with mild-to-moderate depression.
- Conditions
- Mild-to-moderate Depression, Neural Activity, Executive Function (Cognition)
- Trial name
- PRODAN (NCT07667530)
- Testing
- Ecologic® Barrier
- Where
- United Kingdom
- Volunteers
- 76 people
- Sponsor
- University of Reading
Mitochondrial Diseases
Executive Function Disorders and Anxio-depressive Symptomatology in Children and Adolescents With Mitochondrial Pathologies
The major steps forward of the neurosciences in recent years have linked psychiatric diseases, neuropsychological symptoms and brain dysfunctions.
- Trial name
- MITOPSY (NCT03832218)
- Testing
- Psychiatric assessment
- Where
- France
- Volunteers
- 12 people
- Sponsor
- University Hospital, Angers
Tobacco Smoking, Smoking Cessation
Exercise for Depressed Smokers
The purpose of this study is to test the effect of a moderate-intensity aerobic exercise intervention for helping individuals with elevated depressive symptoms to quit smoking.
- Trial name
- NCT02086149
- Testing
- Aerobic Exercise, Health Education
- Where
- United States
- Volunteers
- 231 people
- Sponsor
- Butler Hospital
Alcohol Dependence, Depressive Symptomatology
Chronic Alcohol, Stress Inflammatory Response and Relapse Risk
The purpose of this study is to examine potential stress and immune systems adaptations underlying craving and relapse vulnerability in alcohol dependent (AD) individuals and social drinkers (SDs) with and without high levels of…
- Trial name
- NCT02193204
- Testing
- Personal Stress Imagery, Neutral Imagery
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Yale University
Mild Cognitive Impairment, Depressive Symptoms
HEPPI: Efficacy of a Cognitive-Emotional Intervention for Homebound Older Adults
The main goal of this research is to assess the efficacy of a 10-week home-delivered cognitive-emotional intervention program for homebound older adults presenting Mild Cognitive Impairment (MCI) and depressive and/or anxiety…
- Conditions
- Mild Cognitive Impairment, Depressive Symptoms, Anxiety State
- Trial name
- HEPPI (NCT05499767)
- Testing
- HEPPI
- Where
- Portugal
- Volunteers
- 199 people
- Sponsor
- University of Coimbra
Mental Health Disorders in Adolescents, Emotional Dysregulation
Dog-Assisted Therapy in Adolescents Attending a Child and Adolescent Mental Health Day Hospital
This study aimed to evaluate the feasibility and effectiveness of a dog-assisted therapy program integrated into a Child and Adolescent Mental Health Day Hospital, as well as to explore participants' subjective experiences.
- Conditions
- Mental Health Disorders in Adolescents, Emotional Dysregulation, Anxiety Disorders, Depressive Disorders
- Trial name
- DAT-MH-DH (NCT07663916)
- Testing
- Experimental: Experimental: Dog-assisted therapy + Treatment as usual, Active Comparator: Treatment as usual
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- Hospital Clinic of Barcelona
Mild Cognitive Impairment, Depressive Symptoms
Homebound Elderly People Psychotherapeutic Intervention
This study aims to develop, implement, and assess the feasibility, acceptability, and preliminary efficacy of a 10-week structured and individualized cognitive-emotional intervention program for homebound older adults with Mild…
- Conditions
- Mild Cognitive Impairment, Depressive Symptoms, Anxiety State
- Trial name
- HEPPI (NCT04967378)
- Testing
- HEPPI
- Where
- Portugal
- Volunteers
- 51 people
- Sponsor
- University of Coimbra
Depression, Pregnancy
Effects of Maternal Depressive Symptomatology on Pregnancy Outcomes and Newborn Development --- How is Paternal Psychopathology Involved?
This study aims at investigating the effects of maternal depressive symptomatology on pregnancy outcomes and newborn development. How paternal psychopathology is involved in the association will also be explored.
- Trial name
- NCT01280474
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University WanFang Hospital
Stress, Depressive Symptomatology
Emotional Experiences in Fathers of NICU Infants
This study is designed to evaluate the emotional experiences of fathers who have preterm infants who are hospitalized in a (neonatal intensive care unit)NICU setting.
- Trial name
- NCT00306605
- Testing
- Questionnaire
- Where
- 2 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Emotional Disorder, Post COVID-19 Condition
Efficacy of the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders (UP) in People With Post Covid-19 Condition.
The present multiple baseline single case trial will study the efficacy and acceptability of the "Unified Protocol for the Transdiagnostic Treatment of Emotional Disorders" in the treatment of emotional symptomatology and/or…
- Conditions
- Emotional Disorder, Post COVID-19 Condition, Anxiety Disorders, Depressive Disorder
- Trial name
- NCT05581277
- Testing
- Unified Protocol for Transdiagnostic Treatment of Emotional Disorders
- Where
- 2 sites in Spain
- Volunteers
- 60 people
- Sponsor
- Instituto de Investigación Sanitaria Aragón
Depression
Effects of Buprenorphine on Mood in Adults With a Range of Depressive Symptomatology
This study seeks to to study the effects of buprenorphine, a partial mu-opioid agonist, on depressed mood in a healthy young adults with a range of depressive symptomatology.
- Trial name
- BED (NCT02659787)
- Testing
- 0.2mg Buprenorphine
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Head and Neck Carcinoma
Virtual Reality Interventions for the Improvement of Depression, Anxiety and Pain in Patients With Head and Neck Cancer and Caregivers
This clinical trial tests how well a three-dimensional (3D) mindfulness virtual reality (VR) versus (vs) two-dimensional (2D) non-immersive interventions works in improving depression, anxiety, pain, and/or stress in patients…
- Trial name
- NCT06985784
- Testing
- Interview, Medical Device Usage and Evaluation, Questionnaire Administration
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Anxious-Depressive
Mindfulness-based and Compassion-based Interventions in Anxious-Depressive Symptomatology in Mental Health Services
The aim of this study is to assess and compare the benefits of twopsychological interventions added to the usual treatment of patients whocome to mental health.
- Trial name
- NCT03425487
- Testing
- Mindfulness based Intervention, Compassion based Intervention, TAU
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Hospital Miguel Servet
Depressive Disorder, Major, Asthma
Impact of Caregiver Depression on Asthma in the Child
This study will examine if depression in a primary caregiver is associated with more hospitalization or ER visits in children with asthma.
- Trial name
- NCT00223288
- Testing
- Lexapro
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- University of Texas Southwestern Medical Center
Vitamin D Deficiency, Depressive Symptoms
Supplementation and Depressive Symptomatology Incidence Among Saudi Arabian Adults
The goal of this randomized controlled trial is to explore the relationship between Vitamin D supplementation and depressive symptomatology in Saudi Arabian Population.
- Trial name
- NCT05916053
- Testing
- Vitamin D supplementation
- Where
- Saudi Arabia
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Lebanese American University
Depressive Symptomatology, Psychological Distress
The COVID-19 Pandemic and Exercise Study
The COPE Trial is a randomized controlled trial that will provide currently isolated yet generally physically healthy 18-64 year old adults who are pre-retirement with the opportunity to receive a free 3-month subscription to…
- Conditions
- Depressive Symptomatology, Psychological Distress, Health Behavior
- Trial name
- COPE (NCT04400279)
- Testing
- Yoga group, High Intensity Interval Training group, Combination
- Where
- Canada
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Burnout Syndrome, Anxiety Depression
Prevention of Burnout in Spanish Healthcare Professionals Through Attachment-Based Compassion Therapy (ABCT)
Burnout is a common problem among healthcare professionals and may affect their psychological well-being, quality of life, and professional functioning.
- Conditions
- Burnout Syndrome, Anxiety Depression, Stress
- Trial name
- NCT07698379
- Testing
- Attachment-based compassion therapy Compassion, Relaxation program
- Where
- Spain
- Volunteers
- 180 people
- Sponsor
- Hospital Miguel Servet
Training Group, Control Group
Efficacy of an Autobiographical Memory Specificity and Savoring Training for the Reduction of Depressive Symptomatology
The effect of autobiographical memory specificity and savoring training on memory specificity, positive affect regulation, well-being and depression symptomatology
- Trial name
- PESCAR (NCT05220618)
- Testing
- Autobiographical Memory Specificity and Savoring Training: PESCAR
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- University of Valencia
Major Depressive Disorder
Effects of Respiratory-Gated Transcutaneous Vagal Nerve Stimulation in Major Depression (Phase 1)
This study will evaluate the short term effects of respiratory-gated transcutaneous vagus nerve stimulation on the regulation of cardiovagal activity, depressive symptomatology and immune function in subjects with major…
- Trial name
- NCT04607226
- Testing
- Active transcutaneous vagus nerve stimulation
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Massachusetts General Hospital