Clinical trials: Depressive Syndrome
Drug-withdrawal., Drug Abuse
Clinical Studies on the Therapeutic Effects of Mirtazapine on Drug-craving in Cocaine Addicts.
INTRODUCTION. One of the main problems of the treatment of cocaine-dependent patients is the high rate of relapses occurs within the first months after detoxification.
- Conditions
- Drug-withdrawal., Drug Abuse, Drug-induced Depressive State, AOD Craving
- Trial name
- MADC (NCT01949571)
- Testing
- Mirtazapine (REMERON, Schering-Plough-Organon)
- Where
- Mexico
- Volunteers
- 64 people
- Sponsor
- Instituto Nacional de Psiquiatría Dr. Ramón de la Fuente
Premenstrual Dysphoric Disorder (PMDD)
Occupational Physicians Facing Premenstrual Dysphoric Disorder: Knowledge, Perceptions and Practices in Occupational Health
This study aims to assess the knowledge, perceptions and practices of occupational physicians regarding premenstrual dysphoric disorder (PMDD), a condition with significant occupational impact that remains insufficiently explored…
- Trial name
- TDPM (NCT07864285)
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Strasbourg, France
Depression - Major Depressive Disorder, Depression Disorders
Meditative Neurofeedback for Depression
The goal of this study is to test a meditative neurofeedback intervention for depressed mood.
- Trial name
- MediNF (NCT06675240)
- Testing
- MediNF
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, San Diego
Major Depression, Temporal Lobe Epilepsy
Escitalopram Treatment of Major Depression in Patients With Temporal Lobe Epilepsy
This is a research study evaluating the use of escitalopram (Lexapro®) for the treatment of major depression in subjects with temporal lobe epilepsy.
- Trial name
- NCT00595699
- Testing
- escitalopram
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Conrad, Erich J., M.D.
Post-Intensive Care Syndrome, Depressive Symptoms
Pilot Study of a Multidisciplinary Intervention in ICU Survivors at Risk for Psychological or Physical Morbidity
Pilot study of the feasibility and utility of an early, in-hospital multidisciplinary intervention in ICU survivors at risk for psychological and physical problems post-ICU stay
- Conditions
- Post-Intensive Care Syndrome, Depressive Symptoms, Anxiety, Physical Disability
- Trial name
- IMPRESS (NCT06118606)
- Testing
- Case-manager led multidisciplinary follow-up after intensive care
- Where
- 2 sites in Sweden
- Volunteers
- 41 people
- Sponsor
- Region Stockholm
Depressive Symptoms
Ecological Momentary Intervention for Depressive Symptoms in a Community Sample in Hong Kong
The key aim of the study is to test the efficacy of a 4-week ecological momentary intervention (EMI), as compared with the regular weekly-based intervention (control group), in reducing (1) symptoms of depression and (2)…
- Trial name
- NCT04985422
- Testing
- Smartphone-based Daily Ecological Momentary Intervention, Smartphone-based Weekly-delivered Information
- Where
- Hong Kong
- Volunteers
- 262 people
- Sponsor
- The University of Hong Kong
Depression - Major Depressive Disorder, Adjustment Disorder
Health and Work Ability Following Inpatient Treatment for Stress-related Disorders - Follow-up Study of the HARMODI Cohort
When treating stress-related conditions, it is important to understand how health and work ability develop over the long term. In our research project, we aim, firstly, to investigate how health and work ability develop over the…
- Conditions
- Depression - Major Depressive Disorder, Adjustment Disorder, Burnout Syndrome
- Trial name
- NCT07757997
- Where
- 2 sites in Switzerland
- Volunteers
- 143 people
- Sponsor
- Clinica Holistica Engiadina
Insomnia, Post Partum Depression
Insomnia and Rumination in Late Pregnancy and the Risk for Postpartum Depression
The primary objective of the proposed research is to determine whether prenatal insomnia and ruminative thinking predict severity of postpartum depression (PPD) symptoms.
- Trial name
- PPD (NCT03596879)
- Testing
- dCBTI, Sleep Education
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- Henry Ford Health System
Major Depressive Disorder, Metabolic Syndrome
Incidence of Metabolic Syndrome and Thyroid Dysfunction in Patients With Major Depressive Disorder
Aim 1 is to study prevalence and 1 year incidence of metabolic syndrome in major depressive disorder and factors correlation. Aim 2 is to study prevalence and 1 year incidence of thyroid dysfunction in major depressive disorder…
- Conditions
- Major Depressive Disorder, Metabolic Syndrome, Thyroid Dysfunction
- Trial name
- NCT01682785
- Volunteers
- 140 people
- Sponsor
- Chiang Mai University
Premenstrual Dysphoric Disorder
A Study of Efficacy and Safety of Sepranolone (UC1010) in Patients With Premenstrual Dysphoric Disorder (PMDD)
The objective of this phase IIb study is to evaluate the effect and safety of Sepranolone (UC1010) on premenstrual symptoms in women with Premenstrual Dysphoric Disorder (PMDD).
- Trial name
- NCT03697265
- Testing
- Sepranolone (UC1010) low dose, Sepranolone (UC1010) high dose
- Where
- 12 sites in Germany, Poland and 2 more
- Volunteers
- 475 people
- Sponsor
- Asarina Pharma
Postpartum Depression, Postpartum Anxiety
The Mom and Infant Outcomes (MOMI) Study
The investigator's long-term goal is to mitigate pregnancy-related mortality (PRM) risk by systematically delivering scalable integrated clinical and supportive care that is effective for all.
- Conditions
- Postpartum Depression, Postpartum Anxiety, Cardiometabolic Syndrome
- Trial name
- NCT06277661
- Testing
- MOMI PODS, Enhanced Usual Care (EUC)
- Where
- United States
- Volunteers
- 384 people
- Sponsor
- Ohio State University
Premenstrual Disorder
The Effect of Progressive Muscle Relaxation Exercises on Premenstrual Syndrome, Anxiety, and Tendency to Violence in Young Women
This study results will provide evidence on the effectiveness of Progressive Muscle Relaxation Exercises (PMRE) as a complementary method in improving Premenstrual Syndrome (PMS), an important women's health issue.
- Trial name
- NCT06909955
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Cardiovascular Diseases, Acute Coronary Syndrome
MBCT Via Group Videoconferencing for Acute Coronary Syndrome Patients With Depressive Symptoms: A Pilot RCT
The aim of this study is to establish, in a pilot RCT (approx. N=50 participants) with a time- and attention-matched health enhancement control, (a) the feasibility of the recruitment procedures (screening, eligibility…
- Conditions
- Cardiovascular Diseases, Acute Coronary Syndrome, Depression
- Trial name
- NCT04799899
- Testing
- Adapted MBCT, Cardiac Health Enhancement
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Massachusetts General Hospital
Post-Concussion Symptoms, Insomnia
Neurotechnology Following Traumatic Brain Injury
This two-part study seeks to improve symptoms such as pain and sleep problems after concussion, or mild traumatic brain injury (mTBI).
- Conditions
- Post-Concussion Symptoms, Insomnia, Pain, Chronic, Depressive Symptoms
- Trial name
- Cereset (NCT03649958)
- Testing
- HIRREM-SOP or Cereset, Cereset 2x
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Brain State Technologies, LLC
Treatment Resistant Depression (TRD)
Maintenance TMS in Treatment Resistant Depression
Electroconvulsive therapy (ECT) is one of the most efficacious treatments available for treatment-resistant depression (TRD). Although a maintenance ECT protocol exists, multiple barriers limit its use for long-term use.
- Trial name
- NCT06682299
- Testing
- Transmagnetic Stimulation, Electroconvulsive Therapy
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Austin Messner
Major Depressive Disorder, Anxiety Disorder
Tapering Off Antidepressants
The purpose of this study is to compare two ways to stop taking an antidepressant medication and determine whether a faster or slower taper is better tolerated.
- Conditions
- Major Depressive Disorder, Anxiety Disorder, Obsessive Compulsive Disorder, Post-Traumatic Stress Disorder
- Trial name
- NCT02661828
- Testing
- Two-Week Antidepressant Taper Regimen, One-Week Antidepressant Taper Regimen
- Where
- 3 sites in United States
- Volunteers
- 2 people
- Sponsor
- Emory University
Schizophrenia Disorders, Personality Disorders
Recovery in Telling Life Stories
This project tests the Recovery In Telling Life Stories (RETELL) intervention, aimed at supporting personal recovery in people with severe mental illness (SMI).
- Conditions
- Schizophrenia Disorders, Personality Disorders, Obsessive - Compulsive Disorder, Anxiety Disorders
- Trial name
- RETELL (NCT07082777)
- Testing
- Narrative therapy
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- University of Aarhus
Premenstrual Dysphoric Disorder
Intranasal PH80 Spray for Acute Management of the Symptoms of Premenstrual Dysphoric Disorder
The objective of this study is to evaluate the effectiveness and safety in double-blind, randomized, placebo-controlled clinical trials of self administered PH80 intranasal spray for the acute management of cycle related symptoms…
- Trial name
- PH80-PMD (NCT01217775)
- Testing
- PH80
- Where
- United States
- Volunteers
- 1,400 people
- Sponsor
- Pherin Pharmaceuticals, Inc.
Acquired Immunodeficiency Syndrome, Depressive Disorder
Psychosocial Correlates and Coping Strategies Associated With Long-Term Survival of HIV-Infected Children
Children and adolescents with HIV/AIDS are living well beyond life expectancy that was projected for them in the recent past. Little is known about the psychosocial variables that coincide with long-term survival of HIV/AIDS.
- Conditions
- Acquired Immunodeficiency Syndrome, Depressive Disorder, HIV Infections
- Trial name
- NCT00001435
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- National Cancer Institute (NCI)
Iron Deficiency Anemia of Pregnancy, Iron-deficiency
Non-invasive Detection of Iron Deficiency in Obstetrics
Validation of non-invasive measurement of zinc protoporphyrin for detection of iron deficiency in pregnancy. In addition, the impact of iron deficiency on the incidence of postpartum depression, restless legs syndrome, obstetric…
- Conditions
- Iron Deficiency Anemia of Pregnancy, Iron-deficiency, Restless Leg Syndrome in Pregnancy, Restless Leg Syndrome Due to Iron Deficiency Anaemia
- Trial name
- PICCOLINO (NCT07083492)
- Testing
- non-invasive measurement of zink protoporphyrin
- Where
- Germany
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Wuerzburg University Hospital