Clinical trials: Depth of Anesthesia
Depth of Anesthesia (DOA)
Effectiveness of the NeuroSENSE for Monitoring the Hypnotic Depth of Anesthesia
The objective of this clinical study is to investigate whether the NeuroSENSE is an adequate monitor of hypnotic depth-of-anesthesia (DOA).
- Trial name
- NCT02088671
- Testing
- Propofol induction followed by randomized doses of desflurane, Recording of EEG using NeuroSENSE, Data collection
- Where
- 2 sites in Canada
- Volunteers
- 76 people
- Sponsor
- NeuroWave Systems Inc.
Reversing Vecuronium-Induced Neuromuscular Blockade in Patients Undergoing General Anesthesia Surgery, Reversing Rocuronium-Induced Neuromuscular Blockade in Patients Undergoing General Anesthesia Surgery
A Dose-Finding Study of Amogammadex Sodium for Reversing Vecuronium and Rocuronium-Induced Neuromuscular Blockade
Background context: Amogammadex sodium has completed Phase I-III clinical studies in China for reversal of rocuronium-induced blockade. No clinical studies have yet been conducted for vecuronium-induced blockade.
- Trial name
- NCT07595393
- Testing
- Rocuronium (0.6mg/kg), vecuronium bromide (0.1mg/kg)
- Volunteers
- 64 people
- Sponsor
- Amckaus PTY LTD.
Upper Airway Obstruction
A New Flexible Extended-Length Pharyngeal Airway for Deep Sedation
The purpose of this prospective pilot provider adoption study was to evaluate user experience a new airway device in adult patients with airway obstruction under deep sedation. Fifteen hospital systems served as testing sites.
- Trial name
- NCT04419883
- Testing
- McMurray Enhanced Airway
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- McMurray Medical Group, LLC
Anesthesia, General, Neuromuscular Blockade
Efficacy and Safety of 4.0 mg/kg Sugammadex at 1-2 PTC in Chinese and European Subjects (Study 19.4.335)(P05775AM1)(COMPLETED)
The present trial is set up to evaluate the efficacy and safety of 4.0 mg.kg-1 sugammadex in Chinese and Caucasian subjects for registration purposes in China.
- Trial name
- NCT00826176
- Testing
- Sugammadex
- Volunteers
- 164 people
- Sponsor
- Merck Sharp & Dohme LLC
Pain
Evaluate the Depth and Duration of Anesthesia
The purpose of the study is to determine the depth (mm) of anesthesia provided by the Synera topical patch (using sensory depth and pain depth evaluations), and to determine the duration (minutes) of anesthesia provided by the…
- Trial name
- NCT00891163
- Testing
- Synera™ Topical Patch (70 mg lidocaine/70 mg tetracaine)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- ZARS Pharma Inc.
Anesthesia
Comparison of Depth of Sedation Performance Between SedLine and Comparator Device During General Anesthesia
The primary objective is to compare the performance of Masimo's SedLine and the comparator's device systems during surgery. Relative accuracy of the individual depth of sedation indices will be compared.
- Trial name
- NCT03865316
- Testing
- SedLine Vs Comparator Test Group
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Masimo Corporation