Clinical trials: Depth of Anesthesia
Anesthesia
Evaluation of EEG With Respect to the Change of Depth of Anesthesia During General Anesthesia
The BIS Index, one of the VISTA Monitor output parameters, may be used as an aid in monitoring the effects of certain anesthetic agents;and its usage with certain anesthetic agents may be associated with a reduction in primary…
- Trial name
- NCT02586441
- Testing
- Electroencephalography, Propofol, Rocuronium bromide
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Korea University Anam Hospital
Transcervical Resection of Endometrium, Transcervical Resection of Fibroids
Comparing Two Types of Sedation to Gynaecological Patients
The primary endpoint is to investigate the difference in pain between patients who receive deep sedation with spontaneous breathing versus patients who receive general anesthesia.
- Conditions
- Transcervical Resection of Endometrium, Transcervical Resection of Fibroids, Transcervical Resection of Polyp
- Trial name
- NCT01412632
- Testing
- Remifentanil, propofol and citanest
- Where
- Denmark
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Thoracic Diseases, Thoracic Surgery
Deep Serratus Anterior Plane Block vs Surgically-placed Paravertebral Block for VATS Surgery
Thoracic surgery, and surgery involving the chest wall in general, is associated with poorly controlled acute pain, which may result in delayed functional recovery, and may progress to chronic pain.
- Conditions
- Thoracic Diseases, Thoracic Surgery, Rib Fractures, Pain, Postoperative
- Trial name
- SAPB (NCT03768193)
- Testing
- Deep serratus anterior plane block, Surgically-placed paravertebral block
- Where
- Ireland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mater Misericordiae University Hospital
Colorectal (Colon or Rectal) Cancer
Endoscopic Submucosal Dissection of Large Recto-sigmoid Lesions Under Spinal Anesthesia
The investigators collected data on all consecutive patients who underwent ESD for recto-sigmoid laterally spreading tumors (LSTs) >35 mm under SA between January 2021 and March 2024.
- Trial name
- NCT06316401
- Testing
- ESD of large LSTs under SA
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Azienda USL Modena
Airway Complication of Anesthesia
Impact of Labor and Delivery on Ultrasound Measured Cricothyroid Membrane Depth and Height
The cricothyroid membrane acts as a route through which the upper airway can be accessed to provide oxygen and ventilation to patients.
- Trial name
- NCT04546087
- Testing
- Ultrasound
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Opioid Use
Impact of Bilateral Deep Parasternal Intercostal Plane Block on Intraoperative Opioid Consumption in Open Heart Surgery
This study aims to assess the impact of bilateral deep parasternal intercostal plane block on intraoperative opioid consumption in open heart surgery
- Trial name
- NCT05103787
- Testing
- deep parasternal intercostal plane block, control
- Where
- 2 sites in Indonesia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Electroencephalography, Craniotomy Surgery
Evaluation of Response to Pain From Skull Pin Fixation in Craniotomies
The goal of this observational study is to investigate the relationship between the response to skull pin fixation pain and the analysis of blood pressure, heart rate, and brain wave activity in adults undergoing brain surgery.
- Conditions
- Electroencephalography, Craniotomy Surgery, Pain Management
- Trial name
- NCT06811701
- Testing
- Scalp nerve block, Opioid Anesthetics, Local Anesthetic Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Diskapi Teaching and Research Hospital
Shoulder Pain, Anesthesia
The Effect of Deep Neuromuscular Block and Reversal With Sugammadex on Surgical Conditions and Perioperative Morbidity in Shoulder Surgery Using a Deltopectoral Approach
The study evaluates wether deep neuromuscular block during entire surgical procedure to the gleno-humeral joint or the proximal humerus using a deltoideo-pectoral approach results in less muscular damage to the deltoid muscle and…
- Trial name
- NCT03643913
- Testing
- Deep neuromuscular block, Moderate neuromuscular block, Neuromuscular Blocking Agents and reversing agents
- Where
- Belgium
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Oxidative Stress
Does the Use of Bispectral Index Reduce the Oxidative Stress in Endoscopic Retrograde Cholangiopancreatography?
Objective Endoscopic Retrograde Cholangiopancreatography (ERCP) is performed for resolving cholestasis by sphincterotomy and/or stone extraction and is done with deep sedation or general anesthesia.
- Trial name
- NCT02792751
- Testing
- Bispectral Index Monitorisation (BIS), Ramsey Sedation Scale
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Antalya Training and Research Hospital
Pediatric Surgical Procedures Requiring Endotracheal Intubation Under General Anesthesia
Comparison of Optimal Endotracheal Tube Depth Using Four Different Formulas in Children Aged 1-4 Years and Verification With Fiberoptic Bronchoscopy
. The optimal position of the endotracheal tube (ETT) within the trachea is the middle third portion, distal to the vocal cords.
- Trial name
- NCT06937840
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ankara University
Emergence Delirium (Derlenme Deliryumu)
Brain Monitors to Reduce Child Confusion After Anesthesia
The goal of this clinical trial was to learn if using a brain monitor to adjust anesthesia (sleep medicine) during surgery could prevent emergence delirium (severe confusion and agitation upon waking) in children aged 2 to 12…
- Trial name
- NCT07826559
- Testing
- BIS-Guided Anesthesia, Standard Care Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Baskent University
Burn Unspecified Degree, Deep Sedation
Effects Of Different Anesthesia Applications On Mood, Depression, And Anxiety Levels In Burn Patients
Adequate and effective pain management and prevention of depression are essential in burn patients. This study aims to investigate the effects of ketamine sedation in burn patients in terms of mood disorders, depression, anxiety…
- Trial name
- NCT06165848
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- T.C. Sağlık Bakanlığı Ankara Bilkent Şehir Hastanesi
General Anesthesia-Induced Altered Consciousness
Brain Activity and Changes in Consciousness During General Anesthesia
This study aims to investigate how general anesthetics alter brain activity and consciousness across different age groups. The study will evaluate four anesthetic agents with different mechanisms of action: propofol, remimazolam…
- Trial name
- NCT07836205
- Testing
- Propofol (Group P), Remimazolam group, Esketamine group
- Where
- China
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Beijing Chao Yang Hospital
Anesthesia, Anesthesia Awareness
Pediatric Validation of CONOX Monitor During Surgery
Pediatric Validation of CONOX Monitoring device (qCON and qNOX indices) for anesthesia depth during surgery
- Conditions
- Anesthesia, Anesthesia Awareness, Nociceptive Pain, Pediatric ALL
- Trial name
- NCT04826146
- Testing
- Validation of qCON versus BIS
- Where
- 2 sites in Spain
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Patricio Gonzalez Pizarro
Laryngeal Masks
Supraorbital Pressure Versus Jaw Thrust for Assessing the Adequate Depth of Anesthesia for LMA Insertion in Children
BACKGROUND AND OBJECTIVES The purpose of this study is to assess whether the loss of motor response to supraorbital pressure can be an alternative to that of jaw thrust to predict optimal condition for laryngeal mask airway (LMA)…
- Trial name
- NCT02618525
- Testing
- Supraorbital pressure, Jaw thrust maneuver
- Where
- Nepal
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- B.P. Koirala Institute of Health Sciences
Anxiety State, Pediatric ALL
Anxiolytic Effects of Lavender and Orange Oil
The aim of this study is to determine the possible anxiety reducing effects of lavender oil and orange oil on parents with children receiving dental care under sedation during perioperative wait.
- Conditions
- Anxiety State, Pediatric ALL, Dental Anxiety, Oil; Inhalation
- Trial name
- NCT04079309
- Testing
- Lavender/Orange
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ankara University
Thyroid Surgeries, Intraoperative Analgesic Use
qCON/qNOX-Guided Anesthesia in Patients Undergoing Thyroidectomy Surgery
The aim of this study is to evaluate the effect of using the non-invasive Conox monitor on intraoperative opioid consumption. Additionally, the study aims to assess the impact of Conox monitoring on recovery time, postoperative…
- Conditions
- Thyroid Surgeries, Intraoperative Analgesic Use, Anesthesia Depth Monitoring
- Trial name
- NCT07445659
- Testing
- Connox EEG Monitoring, standard anesthesia management
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kayseri City Hospital
Elderly ; Moderate Risk Surgery
Optimized Anesthesia to Reduce Postoperative Cognitive Impairment in the Elderly
The aim of this study is to demonstrate that in elderly and frail patients, a narrower control of intraoperative blood pressure (BP) by the use of a continuous and noninvasive BP monitoring, coupled with an adequate depth of…
- Trial name
- NCT02698982
- Testing
- Depth of anesthesia monitoring (BIS, Covidien USA) and Continus non invasive blood pressure monitoring (Clearsight, Edwards LifeScience, USA), moderate risk surgery
- Where
- Belgium
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Erasme University Hospital
Emergence Agitation
Effect of Extubation Under Deep Anesthesia on Emergence Agitation of Nasal Surgery
This study analyzed the relationship between extubation timing and Emergence agitation in 18-60 years old adults undergoing nasal surgery, such as nasal septum correction, endoscopic sinus surgery, and nasal bone fracture…
- Trial name
- NCT04844333
- Testing
- Extubation under deep anesthesia
- Where
- 3 sites in China
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Pain
Evaluate the Depth and Duration of Anesthesia
The purpose of the study is to determine the depth (mm) of anesthesia provided by the Synera topical patch (using sensory depth and pain depth evaluations), and to determine the duration (minutes) of anesthesia provided by the…
- Trial name
- NCT00891163
- Testing
- Synera™ Topical Patch (70 mg lidocaine/70 mg tetracaine)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- ZARS Pharma Inc.