Clinical trials: Depth of Anesthesia Monitoring, active
Depth of Anesthesia, Nociception
Anesthesia Induction Scheme for Painless Gastrointestinal Endoscopy Patients Based on Nociceptive Stimulation Monitoring
Nociception is the encoding and processing of noxious stimulation and is considered an objective indicator for monitoring pain. Currently, a new clinically-applied medical-engineering integrated monitoring device for noxious…
- Conditions
- Depth of Anesthesia, Nociception, Painless Gastrointestinal Endoscopy
- Trial name
- NCT06604156
- Testing
- EEG monitoring
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Min Su
Brain Tumor Adult, Processed EEG
Processed EEG for Monitoring of Anesthetic Depth in Intracranial Tumor Surgery
An important feature of neurosurgical anesthesia is early postoperative recovery of consciousness with minimal residual sedation.
- Conditions
- Brain Tumor Adult, Processed EEG, Total Intravenous Anesthesia
- Trial name
- NCT06922500
- Testing
- depth of anesthesia
- Where
- Sweden
- Volunteers
- 126 people
- Sponsor
- Region Skane
Anesthesia Depth Monitoring, Analgesia Assessment
Target-Controlled Infusion (TCI) Effectiveness in Hysteroscopy
This prospective, randomized, observational study aims to evaluate the perioperative anesthetic efficacy of different Target-Controlled Infusion (TCI) models-specifically Minto, Schnider, and Eleveld pharmacokinetic models-in…
- Conditions
- Anesthesia Depth Monitoring, Analgesia Assessment, Perioperative Safety and Recovery, Target Controlled İnfusion
- Trial name
- NCT07023263
- Testing
- Schnider+ Mİnto, Eleveld
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Gazi University
Depth of Anesthesia Monitoring, BIS-EEG
The Effects of Midazolam, Dexmedetomidine, and Esketamine on Bispectral Index and Raw Electroencephalogram in Patients Under Propofol-Remifentanil Baseline Anesthesia
This prospective, single-center, randomized interventional study aims to investigate the effects of commonly used adjunct anesthetic drugs on the Bispectral Index (BIS) and electroencephalographic (EEG) activity during total…
- Trial name
- NCT07699523
- Testing
- Midazolam, Dexmedetomidine, Esketamine
- Where
- 2 sites in China
- Volunteers
- 120 people
- Sponsor
- China-Japan Friendship Hospital
Spinal (Fusion) Surgery, Total Intravenous Anesthesia
Comparison of Hemodynamic Responses During Anesthesia Induction Using Eleveld and Schnider
This randomized prospective study aims to compare the effects of two target-controlled infusion models, the Schnider and Eleveld models, on anesthetic depth and hemodynamic responses during anesthesia induction in adult patients…
- Conditions
- Spinal (Fusion) Surgery, Total Intravenous Anesthesia, Target Controlled Infusion of Propofol, Anesthesia Depth Monitoring
- Trial name
- NCT07586189
- Testing
- TCI Propofol Injection Models- Eleveld, TCI Propofol Injection Schnider
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul University
Awareness During General Anesthesia
Is Density Spectral Array Display Along With Bispectral Index Superior to the Display of Bispectral Index Alone
A study to evaluate the use of density spectral array display in comparison with Bispectral index in a clinical setting.
- Trial name
- DSA-Light (NCT07232160)
- Testing
- Depth of anesthesia monitoring using processed EEG
- Where
- Australia
- Volunteers
- 70 people
- Sponsor
- The University of Queensland
Heart Disease
Assessment of Cardiac Function and Anesthesia Depth in Patients Undergoing Cardiac Surgery
The SHAPE study is a prospective, randomized study evaluating changes in cardiac function in adult patients undergoing cardiac surgery with cardiopulmonary bypass.
- Trial name
- SHAPE (NCT07770269)
- Testing
- BIS-guided anesthesia: BIS 45-55, BIS-guided anesthesia: BIS 30-35
- Where
- Greece
- Volunteers
- 70 people
- Sponsor
- AHEPA University Hospital
Deep Sedation, Endoscopic Retrograde Cholangiopancreatography
Bispectral Index-Guided Propofol Sedation During Endoscopic Retrograde Cholangiopancreatography
Endoscopic retrograde cholangiopancreatography (ERCP) requires deep sedation, and propofol is commonly used because of its rapid onset and recovery, but it has a narrow therapeutic window, especially in elderly patients.
- Conditions
- Deep Sedation, Endoscopic Retrograde Cholangiopancreatography, Anesthesia Recovery Period
- Trial name
- BIS-ERCP (NCT07922291)
- Testing
- BIS-Guided Propofol Titration, Standard Clinical Propofol Titration
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Van Training and Research Hospital
General Anesthesia-Induced Altered Consciousness
Brain Activity and Changes in Consciousness During General Anesthesia
This study aims to investigate how general anesthetics alter brain activity and consciousness across different age groups. The study will evaluate four anesthetic agents with different mechanisms of action: propofol, remimazolam…
- Trial name
- NCT07836205
- Testing
- Propofol (Group P), Remimazolam group, Esketamine group
- Where
- China
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Beijing Chao Yang Hospital
Thyroid Surgeries, Intraoperative Analgesic Use
qCON/qNOX-Guided Anesthesia in Patients Undergoing Thyroidectomy Surgery
The aim of this study is to evaluate the effect of using the non-invasive Conox monitor on intraoperative opioid consumption. Additionally, the study aims to assess the impact of Conox monitoring on recovery time, postoperative…
- Conditions
- Thyroid Surgeries, Intraoperative Analgesic Use, Anesthesia Depth Monitoring
- Trial name
- NCT07445659
- Testing
- Connox EEG Monitoring, standard anesthesia management
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kayseri City Hospital
Anesthesia
Research on Anesthesia Depth Control Strategy Based on Continuous and Non-invasive Monitoring of Exhaled Breath
This study aims to propose a strategy for controlling the depth of anesthesia based on continuous and non-invasive monitoring of exhaled breath: BIS value during intravenous-inhalation combined anesthesia is predicted according…
- Trial name
- NCT07272044
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Anesthesia, Intubation, Endotracheal
Patient State Index at Laryngoscopy and Tracheal Intubation Conditions
The goal of this observational study is to learn whether the depth of anesthesia at the moment the breathing tube is placed is related to how easily the tube can be placed, in adult women (18 to 65 years) having planned surgery…
- Conditions
- Anesthesia, Intubation, Endotracheal, Anesthesia Depth Monitoring
- Trial name
- NCT07864402
- Testing
- Depth of anesthesia at laryngoscopy (Patient State Index)
- Where
- Turkey (Türkiye)
- Volunteers
- 162 people
- Sponsor
- Sakarya University
Geriatric Patient Care Improvement, Postoperative Delirium (POD)
The Effects of Anesthesia Depth Monitoring on Postoperative Recovery and Cognitive Functions in the Geriatric Patient Population
This study will be conducted on patients aged 65 and older scheduled for surgery due to lumbar or cervical disc herniation. General anesthesia is routinely used for these types of surgeries in the hospital.
- Conditions
- Geriatric Patient Care Improvement, Postoperative Delirium (POD), Burst Suppression
- Trial name
- NCT06844279
- Testing
- Control Group: Standard Hemodynamic Monitoring, Processed Electroencephalogram (BIS Index), Processed Electroencephalogram (DSA Mode)
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Aslıhan Güleç
Cardiopulmonary Bypass, Hypothermia; Anesthesia
Effect of Hypothermia on BIS and PSI Correlation During Cardiopulmonary Bypass
The goal of this observational study is to evaluate whether hypothermia affects the relationship between electroencephalography-derived indices during cardiac surgery in adult patients undergoing cardiopulmonary bypass.
- Conditions
- Cardiopulmonary Bypass, Hypothermia; Anesthesia, Depth of Anesthesia Monitoring
- Trial name
- NCT07508579
- Testing
- Simultaneous BIS and PSI Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sakarya University
Nociception
Quantitative Consciousness Index Monitoring (qNOX) of Sedation During Endoscopy
Nociception is the encoding and processing of noxious stimulation and is considered an objective indicator for monitoring pain. Currently, a new clinically-applied medical-engineering integrated monitoring device for noxious…
- Trial name
- NCT06777589
- Testing
- Monitoring of anesthesia depth
- Where
- China
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Min Su
Anaesthesia, Anesthesia Depth Monitoring
Monitoring the Depth of Anesthesia and Nociception During the Induction of General Anesthesia in Pediatric Patients
Perioperative assessment of adequate depth of anesthesia and analgesia is currently a recommended part of routine anesthesia practice for all surgical procedures.
- Trial name
- ANIGAPP (NCT07245654)
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- Brno University Hospital
BIS-EEG, PSI
Comparison of the Factors Affecting PSI and BIS Values in Monitoring Anesthetic Depth During Open-Heart Surgery
Measurement of anesthetic depth has long been a subject of investigation, aiming to titrate anesthetic agents appropriately and to prevent intraoperative awareness and consciousness.
- Conditions
- BIS-EEG, PSI, Open Heart Surgery, Anesthesia Depth Monitoring
- Trial name
- NCT07042906
- Testing
- anesthesia depth monitorizing, awareness
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Kocaeli University
Aging, Inflammation
Macrophage/Monocyte Driven Inflammation and Anesthetic Sensitivity in Aging
The goal of this observational study is to determine whether macrophage/monocyte mediated inflammatory signaling contributes to reduced anesthetic requirements in older adults undergoing major abdominal surgery.
- Conditions
- Aging, Inflammation, Blood-Brain Barrier Permeability, Anesthesia Brain Monitor
- Trial name
- MACRO-AGE (NCT07372417)
- Where
- Chile
- Volunteers
- 60 people
- Sponsor
- University of Chile
Low Flow Anesthesia
Low-Flow Anesthesia Without Wash-in: Effects on Oxygenation and Depth of Anesthesia
This study aims to evaluate whether adjusting the fresh gas flow rate to low-flow immediately after intubation, without performing a wash-in, is a reliable approach with respect to depth of anesthesia and oxygenation.
- Trial name
- NCT07534839
- Testing
- Initiation of low-flow anesthesia without wash-in following intubation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Erzincan Binali Yildirim Universitesi
Monitoring of Depth of Anesthesia
Patient Positioning and Its Influence on BIS, NOL, and Cerebral Oxygenation in Anesthetized Patients
The goal of this observational study is to find out how changes in body position during surgery might affect brain monitoring results in patients who are under general anesthesia.The main question it aims to answer is: Does…
- Trial name
- NCT07013734
- Volunteers
- 71 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal