Clinical trials: Dermal Atrophy
Gingival Recession
Tunnel With and Without Intramucosal Vertical Incisions
Thirty patients will be treated: 15 with a coronally positioned tunnel technique plus intramucosal verticals with AlloDerm® (test treatment) and 15 with a coronally positioned tunnel technique alone with AlloDerm® (control…
- Trial name
- NCT02486991
- Testing
- Tunnel + AlloDerm®, Tunnel + AlloDerm® + Verticals
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Dermal Atrophy
Novel Compositions for Treating or Preventing Dermal Disorders
This trial examines the impact of a topical formulation of rapamycin on dermal thickness and senescence.
- Trial name
- NCT03103893
- Testing
- Rapamycin
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Drexel University
Vaginismus, Vaginal Atrophy
Hydration and Acceptability of the Genital and Skin Mucosa of a Vaginal Moisturizer in Menopausal Women
Hyaluronic Acid is indicated for the relief of vaginal dryness, itching, and irritation, or the reduction of vaginal lubrication with prolonged hydration effects for up to 72 hours.
- Conditions
- Vaginismus, Vaginal Atrophy, Menopause
- Trial name
- NCT06564883
- Testing
- 0.20% sodium hyaluronate gel
- Volunteers
- 45 people
- Sponsor
- Biolab Sanus Farmaceutica
Recession, Gingival
Root Coverage Using ADM and Coronally Positioned Tunnel With or Without Enamel Matrix Derivative
24 patients will be treated with a coronally positioned tunnel with AlloDerm RTM with or without the addition of Enamel Matrix Derivative to compare the baseline and 6-month changes in recession defect coverage, clinical…
- Trial name
- NCT05565079
- Testing
- Regenerative tissue matrix and enamel matrix derivative, Regenerative tissue matrix
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Gingival Recession
Porcine Acellular Dermal Matrix for the Treatment of Localized Gingival Recessions
Aim: The aim of this randomized clinical trial is to evaluate the use of the porcine acellular dermal matrix (PADM) for the treatment of RT1 localized gingival recessions.
- Trial name
- NCT06006780
- Testing
- Porcine acellular dermal matrix, Coronally advanced flap (CAF)
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Skin and Connective Tissue Diseases
A Single-Centre Clinical Trial to Assess Steroid Induced Skin Atrophy on Healthy Skin
The purpose of this study is to assess steroid induced skin atrophy by sonography.
- Trial name
- NCT02355639
- Testing
- Clobetasol propionate 0.05 % ointment, Betamethasone dipropionate 0.064 % ointment, Petrolatum ointment
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- LEO Pharma
Gingival Recession
Gingival Augmentation and Root Coverage With Superficial and Deep Cut Acellular Dermal Matrices
This entire protocol involves procedures that are standard care and will randomize subjects to of one two routine care procedures. Patients needing root coverage for gingival recession will be enrolled.
- Trial name
- NCT05956496
- Testing
- Allograft Material ADM-S, Allograft Material ADM-D
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Lichen Sclerosus of External Female Genital Organs
Lichen Sclerosus - Treatment With Triamcinolone Acetonide: Injections (Syringe and Needle) x Micro Injections (MMP Technique)
This research is about a genital disease known as Lichem Sclerosus and Atrophic. It mainly affects women over 18 years of age. The treatment will involve injections of a medicine that contains cortisone, using two different…
- Trial name
- NCT06079645
- Testing
- Infiltration of triamcinolone acetonide (2mg/ml) through syringes and needles, Infiltration of triamcinolone acetonide (40 mg/ml) with needles
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Clinica Dermatologica Arbache ltda
Gingival Recession
Coronally Advanced Flap in Combination With Acellular Dermal Matrix and Enamel Matrix Derivatives for Root Coverage
The aim of this study is to compare the clinical outcomes of root coverage procedures, using coronally advanced flap in combination with acellular dermal matrix with or without enamel matrix derivatives .
- Trial name
- NCT00720707
- Testing
- CAF+ADM+EMD, CAF+ADM
- Where
- Iran
- Volunteers
- 18 people
- Sponsor
- Tabriz University
Gingival Recession
Root Coverage Comparing an Allograft to a Bovine Xenograft
Root coverage with acellular dermal matrix using the coronally positioned tunnel technique comparing two different donor materials
- Trial name
- NCT02810067
- Testing
- Tunnel + AlloDerm, Tunnel + Novomatrix
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Louisville
Skin Aging of Face and Hands, Cicatrix
A Clinical Study Testing How Well the Medical Device HTIC (a Type of Animal-derived Collagen) Works in Treating Skin Problems, Such as Scars, Loss of Firmness, and Volume in Certain Areas of the Face and Body
This clinical trial aims to evaluate the efficacy of the experimental medical device HTIC, which contains Type I collagen of animal origin, in treating skin defects such as scars, loss of tone, and volume in certain areas of the…
- Conditions
- Skin Aging of Face and Hands, Cicatrix, Scars, Atrophic Scar
- Trial name
- NCT07153393
- Testing
- Type I Bovine Collagen (HTIC)
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- Centro Studi Dermatologici S.r.l.
Soft Tissue Atrophy, Mucogingival Deformity on Edentulous Ridge
Behavioral Comparison of Three Different Graft Materials to Increase Soft Tissue Thickness Around Dental Implants.
The purpose of the study is to compare soft tissue volume changes in terms of volume gain and stability around dental implants and PROMS in cases where a sub-epithelial connective tissue graft (SCTG) from the palate, Porcine…
- Conditions
- Soft Tissue Atrophy, Mucogingival Deformity on Edentulous Ridge, Edentulous Alveolar Ridge
- Trial name
- NCT04766255
- Testing
- Soft Tissue graft augmentation, Implant Placement
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Volume Loss (Soft Tissue Ptosis or Atrophy )
Pan Facial Volume Restoration
The aim of this study is to assess performance and tolerance as well as investigator and subject satisfaction further to pan-facial volume restoration with a new cross-linked hyaluronic acid dermal filler containing lidocaine…
- Trial name
- EVE (NCT01545557)
- Testing
- Hyaluronic acid dermal filler gel
- Where
- 3 sites in Brazil
- Volunteers
- 60 people
- Sponsor
- Galderma R&D
Gingiva Atrophy, Gingivitis
Acellular Dermal Matrix Allograft Versus Free Gingival Graft
The present split-mouth controlled randomized clinical trial aimed to evaluate clinical and histological results of acellular dermal matrix allograft (ADM) compared to autogenous free gingival graft (FGG)
- Trial name
- NCT03251001
- Testing
- Control, Acellular Dermal Matrix
- Where
- Brazil
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Cutaneous Atrophy Due to Corticosteroids
Interest of Topical Spironolactone's Administration to Prevent Corticoid-induced Epidermal Atrophy
The purpose of this study is to determine whether spironolactone could significantly reduce cutaneous atrophy due to corticosteroids.
- Trial name
- SPIREPI (NCT01407471)
- Testing
- Clobetasol + Spironolactone
- Where
- France
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Gingival Recession, Generalized
Efficiency of PRP on Acellular Dermal Matrix Application in the Treatment of Multiple Adjacent Gingival Recessions
The aim of this study was to evaluate the effectiveness of platelet rich plasma (PRP) combined with coronally advanced flap plus acellular dermal matrix application (CAF+ADM) in the treatment of multiple adjacent gingival…
- Trial name
- PRP (NCT03043638)
- Testing
- CAF+ADM+PRP, CAF+ADM
- Volunteers
- 12 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Wrinkle
Study to Evaluate the Performance and Safety of the Medical Device Plenhyage®
The Research Question of the present study is the following: in a population of men and women affected by face wrinkles and skin tones and irregularities (atrophies) of the skin surface in neck, abdomen, thighs and buttocks, will…
- Trial name
- Plenhyage (NCT04650620)
- Testing
- Plenhyage® thin, Plenhyage® medium, Plenhyage® strong
- Where
- Romania
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- I.R.A. Istituto Ricerche Applicate S.p.A.
Connective Tissue Graft, Gum Recession
Microderm for Root Coverage Procedures
This randomized pilot study will compare Acellular Dermal Matrix (ADM) and a microsurfaced Acellular Dermal Matrix (mADM) for wound healing, root coverage, gum tissue coverage of the surgical site, blood flow to the site, and…
- Trial name
- NCT07203326
- Testing
- Alloderm, MicroDerm
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Senile Purpura, Bateman's Purpura
Broad Band Light for the Treatment and Prevention of Senile Purpura
There will be five subjects over the age of 65, each with at least one ecchymotic lesion on each arm measuring at least one cm, and five control subjects under the age of 35, both who will be randomized to undergo 4 Sciton Broad…
- Trial name
- NCT03690375
- Testing
- Broad Band Light (BBL)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Siperstein Dermatology
Gingival Recession
Clinical Comparison Between Two Surgical Techniques for the Treatment of Gingival Recessions
The aim of this study is to test a surgical technique for the treatment of gingival recessions. The hypothesis of the study is to promote greater root coverage and better healing.
- Trial name
- NCT01175720
- Testing
- Periodontal surgery to gingival recessions
- Where
- Brazil
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo