Clinical trials: Dermal Filler
Volume Deficiency of the Midface
Comparative Ultrasound Analysis of Two Hyaluronic Acid Dermal Fillers
To assess and compare tissue aggregation and visualization of two Hyaluronic Acid fillers via ultrasound
- Trial name
- RES (NCT05622851)
- Testing
- Restylane Contour, Juvederm Voluma
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Skin Manifestations
New Regenerative Approach for Dermal Renovation (Karisma)
Purpose/Objectives of the Study: Regenerative medicine, as well as aesthetic plastic surgery and dermatology field persistently seeks innovative, minimally invasive interventions to enhance skin quality and mitigate signs of…
- Trial name
- Karisma (NCT06152718)
- Testing
- Karisma
- Where
- 2 sites in Italy, Serbia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Palermo
Facial Rejuvenation
Assessment of the Safety and Efficacy of the Dermal Filler "mARG-01-17" in Facial Rejuvenation Therapy
The aim of the clinical investigation is to evaluate the performance of the mARG-01-17 dermal filler in the context of its efficacy and safety.
- Trial name
- NCT04643977
- Testing
- mARG-01-17 (mesohyal AGRIBENONE)
- Where
- Bulgaria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mesoestetic Pharma Group S.L.
Aging Problems
Needless Laser Injector for Antiaging Effect of Dermal Filler
The investigators aimed to evaluate the efficacy and safety of needless laser injector for antiaging effect of dermal filler.
- Trial name
- NCT05685667
- Testing
- needless laser injector (Mirajet), needle injection
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Moderate to Severe Midface Volume Deficit
Post-Approval Study of Saypha® ChIQ™ for Midface Augmentation in Subjects With Fitzpatrick Skin Types V and VI
The goal of this clinical trial is to further characterize the safety profile of saypha® ChIQ™ for midface augmentation in adults with Fitzpatrick Skin Types V and VI who have moderate to severe midface volume deficit.
- Trial name
- Volido PAS (NCT07918443)
- Testing
- Crosslinked hyaluronic acid dermal filler with lidocaine
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Croma-Pharma GmbH
Aging, Chin Retrusion
Safety and Effectiveness Evaluation of TEOSYAL® TPVM Versus COMPARATOR for the Remodeling of the Lower Face
The clinical study is designed to prospectively evaluate the safety and effectiveness of TEOSYAL® TPVM when compared to COMPARATOR for the remodeling of the lower face
- Trial name
- LIFTUP (NCT05986630)
- Testing
- TEOSYAL® TPVM, COMPARATOR
- Where
- Switzerland
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Teoxane SA
Aging
Evaluation of the Mechanism of Action of Platelet Rich Fibrin Matrix (PRFM) in Producing Skin Volume Augmentation
Autologous platelet rich fibrin matrix will release growth factors which could increase the production of dermal proteins or affect the vascularity and status of neighboring tissues.
- Trial name
- NCT00956020
- Testing
- Platelet rich fibrin matrix
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- The New York Eye & Ear Infirmary
Dermal Filler, Hyaluronic Acid
Evaluate the Safety and Effectiveness of Sodium Hyaluronate When Used for the Correction of Nasolabial Folds
The aim of this study is to evaluate the safety and effectiveness of pain relief of modified sodium hyaluronate gel for injection when used for the correction of moderate or severe nasolabial folds.
- Conditions
- Dermal Filler, Hyaluronic Acid, Lidocaine, Nasolabial Fold
- Trial name
- NCT04569045
- Testing
- HA+Lidocaine, HA
- Where
- 2 sites in China
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- SciVision Biotech Inc.
Chin Regression, Chin Asymmetry
Evaluation of Filler Injection for Chin Profile Enhancement
The goal of this prospective study is to analyze volumetric changes in the lower face after hyaluronic acid filler injections over 90 days.
- Conditions
- Chin Regression, Chin Asymmetry, Jawline Contour Deficit
- Trial name
- NCT07777926
- Testing
- HA Filler
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Lip Augmentation, Lip
RHA® 3 Versus Restylane-L® for Lip Augmentation
This is a multicenter, double-blinded, randomized, prospective, controlled clinical study to identify whether RHA® 3 is non-inferior to Restylane-L® for lip augmentation at Week 12 after the last treatment (initial or touch-up).
- Trial name
- NCT04540913
- Testing
- RHA 3, Restylane-L
- Where
- United States
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Teoxane SA
Nasolabial Fold Correction, Facial Aging
Bridging Technique Validation for Nasolabial Folds JN-BRIDGE-1
The goal of this clinical study is to learn whether the Bridging Technique can safely and effectively treat nasolabial folds (NLF, also known as smile lines) in adults.
- Conditions
- Nasolabial Fold Correction, Facial Aging, Skin Rejuvenation, Wrinkles Such as Nasolabial Folds
- Trial name
- BRIDGING (NCT07178119)
- Testing
- (Bridging) Horizontal Cannula Technique for Treatment of Nasolabial Folds using AILEENE Vol. 2
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dr. Joseph M Novoa Libermann
Skin Folds, Wrinkle
Clinical Investigation to Assess Safety and Performance of Dermal Filler of Hyaluronic Acid
The objective of this clinical investigation is to assess the safety and performance of dermal filler of hyaluronic acid to provide firmness and counteract sagging for the correction of deep wrinkles and imperfections in the…
- Trial name
- NCT05450380
- Testing
- LIFT001
- Where
- 2 sites in Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mesoestetic Pharma Group S.L.
Facial Aging, Skin Rejuvenation
Performance and Safety of Semical Dermal Fillers in Facial Rejuvenation
The aim of the study is to verify safety and performance of Semical dermal fillers according to real-world data.
- Conditions
- Facial Aging, Skin Rejuvenation, Volume Defects in the Mid-face, Lip Augmentation and Correction of Perioral Rhytids
- Trial name
- SEMDERMA (NCT07160777)
- Testing
- cross-linked hyaluronic acid, Mesolifter
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Semikal Technology
Correction of Nasolabial Folds
A Clinical Investigation of the Decoria® Aesthetic Group (DAG) for Correction of Nasolabial Folds (NLF)
Decoria intense is a class III medical device and is CE-marked and has been on the market since 2014. Decoria intense is a hyaluronic acid filler that will be used according to intended use for correction of nasolabial folds.
- Trial name
- Decorate01 (NCT05235126)
- Testing
- Decoria intense
- Where
- 2 sites in Sweden
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Bohus Biotech AB
Aging
Comparing Injections With Poly-L-Lactic Acid in the Temporal Fossa vs. Extended Temporal Fossa + Hairline
The use of poly-L-Lactic acid (PLLA) has demonstrated significant improvement in multiple facial and body regions. Its use in the temporal fossa is the ideal location to demonstrate its impact on neocollagenesis given its…
- Trial name
- NCT06337747
- Testing
- Traditional technique, Experimental technique
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Erevna Innovations Inc.
Dermal Fillers
Pivotal Study to Evaluate the Efficacy and Safety of Injection With LASBEAU Strong in Correction of Nasolabial Folds
Background: Nonsurgical injectable treatments have become popular for aesthetic purposes. In recent years, cross-linked hyaluronic acid (HA) fillers containing lidocaine have been used to correct the nasolabial folds.
- Trial name
- NCT06310863
- Testing
- LASBEAU Strong or Restylane Lyft injection as hyaluronic acid fillers
- Where
- South Korea
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Healthy Male and Female Subjects
Histological Analysis of CelluJuve® Injections in the Brachium
Single-center, exploratory study assessing the safety and histological presentation of CelluJuve® injected into the brachium of healthy volunteers
- Trial name
- NCT06930209
- Testing
- CelluJuve®
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Spiderwort Biotechnologies Inc.
Dermal Filler
Safety and Efficacy of the HA-based Dermal Fillers HYAPROF® SOFT and HYAPROF® BALANCE
Purpose of this study is the demonstration of safety and efficacy of the dermal fillers HYAPROF® SOFT and HYAPROF® BALANCE for restoration of the facial volume and contour.
- Trial name
- PMCF_HYAPROF (NCT04546152)
- Testing
- HYAPROF® SOFT and HYAPROF® BALANCE
- Where
- 2 sites in Germany
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- BioSCIENCE GmbH
Facial Wrinkles
Multicenter Study of the Safety and Effectiveness of Dermal Filler, Belotero®.
This was a study to find out how an investigational product, Belotero, compares to a second product in people with facial wrinkles, such as nasolabial folds.
- Trial name
- NCT00876265
- Testing
- Belotero, Zyplast
- Where
- 6 sites in United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Merz North America, Inc.
Nasolabial Folds
Evaluation of Pain With Lidocaine-Mixed Radiesse® Injectable Dermal Filler
To assess pain during nasolabial fold treatment using Radiesse® Injectable Dermal Filler mixed with lidocaine.
- Trial name
- NCT01012661
- Testing
- Radiesse® Injectable Dermal Filler Mixed with Lidocaine, Radiesse® Injectable Dermal Filler without Lidocaine
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Merz North America, Inc.