Clinical trials: Dermatitis
Healthy Volunteer
Safety Evaluation of KX01 Ointment 1% in Japanese Healthy Male Subjects
Skin Irritation and Phototoxicity Study of KX01 Ointment 1% in Japanese healthy male subjects
- Trial name
- NCT05245578
- Testing
- KX01 ointment 1%
- Where
- Japan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- PharmaEssentia
Contact Dermatitis
A Safety, Tolerability, and Dermal Reactogenicity Study of PDC-APB
This is a randomized, double-blind, placebo-controlled, single ascending dose study to assess the safety and tolerability of PDC-APB by intramuscular (IM) injection compared to placebo.
- Trial name
- NCT04853823
- Testing
- PDC-APB
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Hapten Sciences, Inc.
Dermatitis, Atopic
Histamine Pharmacogenetics in Children With Atopic Dermatitis
The primary goal of the study is to investigate the impact of a common genetic polymorphism in a histamine detoxification enzyme that may well have a common role in regulating the expression of atopic dermatitis (AD) and other…
- Trial name
- NCT00277433
- Testing
- Buccal Swab
- Where
- 7 sites in United States
- Volunteers
- 751 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Atopic Dermatitis, Healthy Participants
A Study of BYN-001 in Healthy Adults and in Adults With Moderate to Severe Atopic Dermatitis
This first-in-human study evaluates BYN-001, a humanized IgG1 monoclonal antibody targeting interleukin-25 (IL-25), a cytokine implicated in atopic dermatitis.
- Trial name
- BYN-001-101 (NCT07746817)
- Testing
- BYN-001
- Where
- Australia
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Bionyra Pharma
Irritant Contact Dermatitis
Glycyrrhetinic Acid and Acute Irritant Dermatitis
Irritant dermatitis is one of the most common inflammatory skin disorders, caused by exposure to external substances that induce inflammation and immune activation.
- Trial name
- NCT07286487
- Testing
- SLS induced irritation, No Treatment, Low Dose Glycyrrhetinic Acid Formulation
- Where
- Croatia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Split, School of Medicine
Eczema/Atopic Dermatitis, Cancer
Patient Forward Access to Clinical and Technological Research: Genetic Influences on Cancer and Atopic Dermatitis
This Patient Forward study intends to conduct research to investigate potential genetic factors causing cancer and eczema/atopic dermatitis.
- Trial name
- PFACTR02 (NCT04362852)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Atopic Dermatitis
A Study of BBT001 in Healthy Volunteers (HVs) and in Adult Patients With Moderate to Severe Atopic Dermatitis (AD)
This is a Phase 1, randomized, blinded, placebo controlled, single ascending dose (SAD) study of BBT001 in healthy volunteers (HVs) and adult patients with moderate to severe Atopic Dermatitis (AD).
- Trial name
- NCT07239947
- Testing
- BBT001
- Where
- 10 sites in China
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Bambusa Therapeutics
Diaper Dermatitis, Diaper Rash
Effect of Video-Based Diaper Dermatitis Care Education on Mothers' Knowledge Level and Dermatitis Severity: A Randomized Controlled Trial
This study was conducted using a randomized controlled, pretest-posttest comparative experimental design to examine the effects of diaper dermatitis care training provided to primiparous mothers on mothers' knowledge and the…
- Conditions
- Diaper Dermatitis, Diaper Rash, Diaper Dermatitis Healing
- Trial name
- NCT07205055
- Testing
- video training
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Seborrheic Dermatitis
Seborrheic Dermatitis: Ketoconazole 2% Foam Versus Ketoconazole 2% Shampoo
The aims of this study are to compare the effectiveness of antifungal foam versus antifungal shampoo and determine patient compliance and satisfaction with both vehicles among African American females with dandruff practicing…
- Trial name
- NCT01203189
- Testing
- ketoconazole 2% foam
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- St. Louis University
Atopic Dermatitis, Eczema
The Effects of Emollient Therapy on the Skin Barrier
The goal of this study is to better understand what effect emollients (moisturizers) have on the skin in young children and adults.
- Trial name
- EES (NCT01291940)
- Testing
- Pediatric Moisturizer, Adult Moisturizer
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Dermatitis
A Clinical Evaluation of 3M Cavilon Advanced Barrier Film for the Treatment of Incontinence Associated Dermatitis (IAD)
The purpose of this study is to obtain information concerning the safety and effective use of a protective barrier film in patients experiencing severe incontinence associated dermatitis.
- Trial name
- NCT02724449
- Testing
- Cavilon Advanced Barrier Film
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Solventum US LLC
Psoriasis, Aging
Effects of Tildrakizumab on Epigenetic Age
Design: Single-center open-label clinical trial. Objective: Evaluate if tildrakizumab reverses peripheral blood leukocyte DNA methylation (epigenetic aging) observed in chronic psoriasis. Number of subjects: 30.
- Conditions
- Psoriasis, Aging, Epigenetic Disorder, Inflammation; Skin
- Trial name
- NCT05110313
- Testing
- TILDRAKIZUMAB
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Carlos Wambier
Atopy, Atopic Dermatitis Eczema
Breast Milk: Influence of the Micro-transcriptome Profile on Atopy in Children Over Time
This is an observational cohort study of 221 breast-feeding mother-infant dyads delivered at term. The goal of the study is to investigate whether levels of immune-related microRNAs (miRNAs) in maternal breast milk (MBM)…
- Conditions
- Atopy, Atopic Dermatitis Eczema, Wheezing, Food Allergy in Infants
- Trial name
- IMPACT (NCT04017520)
- Where
- United States
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Asthma
Use of a Probiotic Supplement to Prevent Asthma in Infants
The goal of the study is to understand the mechanisms of how antigen presentation affects the developing immune system and subsequently affects susceptibility to, or protects against, asthma development.
- Trial name
- NCT00113659
- Testing
- Probiotic
- Where
- United States
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Healthy Volunteers
Study to Access the Relative Bioavailability of Subcutaneous Dose of Nemolizumab When Administered Via Auto-Injector Versus Dual-Chamber Syringe
This study was to compare the rate and extent of absorption of a single dose of nemolizumab administered with auto-injectors [AI] (test) versus dual-chamber syringes [DCS] (reference) under controlled conditions in healthy adult…
- Trial name
- NCT05405985
- Testing
- Nemolizumab
- Where
- 2 sites in United States
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Healthy, Dermatitis, Atopic
A Study of LY3844583 in Healthy Participants and Participants With Atopic Dermatitis
The main purpose of this study is to evaluate the safety and tolerability of LY3844583 in healthy participants and participants with atopic dermatitis (AtD).
- Trial name
- NCT05486208
- Testing
- LY3844583
- Where
- 3 sites in United States, Japan
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Eczema, Dermatitis
Effects of Treatments on Atopic Dermatitis
Background: Atopic dermatitis, or eczema, is a chronic skin disorder. Patients sometimes have infections with S. aureus bacteria.
- Conditions
- Eczema, Dermatitis, Skin Diseases, Genetic, Dermatitis, Atopic
- Trial name
- NCT01631617
- Testing
- Trimethoprim/sulfamethoxazole (TMP/SMZ), Cephalexin, Doxycycline
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Atopic Dermatitis
Longitudinal Endotyping Of Atopic Dermatitis Through Transcriptomic Skin Analysis
This is a multi-center, longitudinal study which will characterize the gene expression profiles and transcriptomic endotypes that underlie mild and moderate-severe Atopic dermatitis (AD) and will determine changes in these…
- Trial name
- LEADS (NCT05436535)
- Testing
- Dupilumab, Vanicream- Dupilumab-naïve, Triamcinolone Acetonide
- Where
- 10 sites in United States
- Volunteers
- 433 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Atopic Diathesis, Eczema-prone Skin
Assessment of Skin Tolerance and Efficacy of a Cosmetic Product After 5 Days of Use on Subjects With Atopic Dermatitis
The aim of this study is to compare the efficacy and tolerability and of a cosmetic product to one that is already available on the market (benchmark product).
- Trial name
- NCT05807113
- Testing
- Atopi intensive care BNO 3731, Benchmark product
- Where
- Germany
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Bionorica SE
Photoallergy
To Test for Photo Allergy Reaction of Sunscreens
The primary objective of this tudy was to evaluate the potential of photoallergy of of sun care products Sun Protection Factor (SPF) 50 Y65 110, SPF 50 Y51 002, and SPF 15 V27 104 application compared to that of a negative…
- Trial name
- NCT02872220
- Testing
- SPF 50 Y65 110 (BAY987519), SPF 50 Y51 002 (BAY987519), SPF 15 V27 104 (BAY987519)
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Bayer