Clinical trials: Dermatitis
Atopic Dermatitis, Vascular Inflammation
Trial on Vascular Inflammation in Atopic Dermatitis
A total of 30 subjects with moderate to severe atopic dermatitis. Thirty subjects without AD matched for sex, age and coronary artery disease risk factor with the AD subjects will also be included.
- Conditions
- Atopic Dermatitis, Vascular Inflammation, Coronary Atherosclerosis
- Trial name
- NCT02926807
- Testing
- FDG-PET Scan, MDCT, biopsy and blood collection
- Where
- Canada
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Innovaderm Research Inc.
Dermatitis, Atopic
Efalizumab for Moderate to Severe Atopic Dermatitis
The purpose of this study is to determine if Raptiva will have beneficial effects in the treatment of patients with moderate to severe atopic dermatitis.
- Trial name
- NCT00226057
- Testing
- Raptiva
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Atopic Dermatitis
Dupilumab-pediatric Skin Barrier Function and Lipidomics Study in Patients With Atopic Dermatitis in China
This is a 32-week, open-label, exploratory study with a 4-week screening period, 16-week treatment phase designed to investigate dupilumab's effect on skin barrier function as measured by TEWL before and after STS in…
- Trial name
- PELISTAD CN (NCT05680298)
- Testing
- Dupilumab
- Where
- China
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Sanofi
Dermatitis, Seborrheic, Dry Skin; Eczema
Safety and Efficacy of a Topical Scalp Treatment for Dry Scalp Conditions in Children and Adult
The purpose of this study is to evaluate the safety and efficacy of a novel topical treatment for dry scalp conditions, including dandruff, seborrheic dermatitis, and atopic dermatitis.
- Trial name
- NCT03830177
- Testing
- Natural Treatment
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Asthma, Atopic Dermatitis
Polish Mother and Child Cohort Study (REPRO_PL) - Follow up of the Children.
The Polish Mother and Child Cohort is multicentre prospective study on different exposures. Prospective cohort study design enables identification of exposures that may influence pregnancy outcome and chil-dren's health…
- Conditions
- Asthma, Atopic Dermatitis, Food Allergy, Wheezing
- Trial name
- REPRO_PL (NCT01861548)
- Where
- 2 sites in Poland
- Volunteers
- 479 people, healthy volunteers welcome
- Sponsor
- Medical University of Lodz
Dandruff
Antidandruff Lotion Mediating Microbiome Rebalance
Edit Brief Summary: To evaluate the NaP lotion effect to decrease dandruff scoring and microbiome rebalance. Detailed Description: Dandruff is a common scalp disorder affecting almost half of the population of any gender and…
- Trial name
- NCT06813521
- Testing
- NaP1%+VitCG3% leave-on lotion (formula 1256103), vehicle (formula 1256145), reference Octopirox 0.25% (formula 1256149).
- Where
- Portugal
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- L'Oreal
Diaper Dermatitis, Diaper Rash
Effect of Video-Based Diaper Dermatitis Care Education on Mothers' Knowledge Level and Dermatitis Severity: A Randomized Controlled Trial
This study was conducted using a randomized controlled, pretest-posttest comparative experimental design to examine the effects of diaper dermatitis care training provided to primiparous mothers on mothers' knowledge and the…
- Conditions
- Diaper Dermatitis, Diaper Rash, Diaper Dermatitis Healing
- Trial name
- NCT07205055
- Testing
- video training
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Skin Laxity
The Effect of a Healthy Snack on Radiance, Aging and Inflammation of the Skin
The anti-oxidative and anti-inflammatory effects of polyphenolic compounds of almonds have been reported in limited animal studies and may have the potential to improve skin radiance.
- Trial name
- AlmondSkin (NCT04352504)
- Testing
- Almond, Pretzel
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Eczema, Allergy
Probiotics in Prevention of Allergies, Obesity and Caries
During the period of 2000-2003, 179 healthy, term infants with no previous signs of allergic disease were recruited and randomized to daily intake of cereals with or without the addition of Lactobacillus paracasei subspecies…
- Conditions
- Eczema, Allergy, Asthma, Obesity
- Trial name
- ELEFANT (NCT00894816)
- Testing
- Lactobacillus F19
- Where
- Sweden
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Umeå University
Inflammation, Skin Abnormalities
Effects of Bend Beauty's Anti-Aging Formula on Inflammatory Markers
This is a phase IV, randomized, double-blind, placebo-controlled, three-arm, parallel intervention study including three groups of 25 subjects between 35-65 years of age, treated with either Bend Beauty's Anti-Aging Formula, fish…
- Conditions
- Inflammation, Skin Abnormalities, Skin Pigment, Inflammatory Response
- Trial name
- BENCHMARK (NCT03862872)
- Testing
- Anti-Aging Formula, Control Fish Oil
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bend Beauty Inc.
Atopic Dermatitis
The Effect of a Probiotic Intervention in Healthy Subjects and Patients With Atopic Dermatitis
The study was performed to investigate the effects of a probiotic supplementation containing Lactobacillus paracasei Lpc-37, Lactobacillus acidophilus 74-2 and Bifidobacterium animalis subsp. lactis DGCC 420 (B.
- Trial name
- NCT00550472
- Testing
- probiotics
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Jena
Atopic Dermatitis, Atopic Disorders
A Community-based Assessment of Skin Care, Allergies, and Eczema
Atopic dermatitis (AD) affects over 9 million children in the U.S. and often heralds the development of asthma, food allergy, skin infections and neurodevelopmental disorders.
- Conditions
- Atopic Dermatitis, Atopic Disorders, Eczema, Atopic Eczema
- Trial name
- CASCADE (NCT03409367)
- Testing
- Participant choice of over-the-counter emollients: Vaseline, Vanicream, CeraVe Healing Ointment, CeraVe cream, Cetaphil cream
- Where
- 4 sites in United States
- Volunteers
- 1,260 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Dermatitis, Atopic, Pruritus
The Efficacy of 3% Kanuka Oil Versus 1% Hydrocortisone Cream in Patients With Atopic Dermatitis
Atopic dermatitis is a common disease affecting millions worldwide. A common associated symptom in this population is pruritus. We seek to investigate the use of an natural, over-the-counter cosmeceutical to help this population
- Trial name
- NCT06488742
- Testing
- 3% kanuka oil
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nexgen Dermatologics, Inc.
Atopic Dermatitis
Observer-Blinded Dose Escalating, Single Dose to Study Safety and Antimicrobial Efficacy of Gel vs. Placebo
A Randomized, Observer-Blinded, Vehicle Controlled, Single Dose, Dose Escalating, Single Application Within-patient Bilateral Comparison. The goal is to determine the safety and tolerability of DBI-001 Gel vs.
- Trial name
- NCT04192513
- Testing
- J. lividum
- Where
- Dominican Republic
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- DermBiont, Inc.
Atopic Dermatitis, Nature, Human
Sand Play - the Effect of Biodiversity Exposure on Atopic Dermatitis
The prevalence of atopic dermatitis has increased along with urbanization and biodiversity loss. According to biodiversity hypothesis, the main reason is urban lifestyle and reduced contact to microbial diversity.
- Conditions
- Atopic Dermatitis, Nature, Human, Microbial Colonization, Immune System and Related Disorders
- Trial name
- BIWE (NCT06390696)
- Testing
- Microbial intervention
- Where
- 2 sites in Finland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Natural Resources Institute Finland
Microbiota, Eczema
Intestinal Microbiota Composition After Antibiotic Treatment in Early Life
In this prospective observational cohort study the potential clinical consequences of antibiotic use in early life and perturbations in the gastrointestinal microbiota composition due to that antibiotic use are studied.
- Conditions
- Microbiota, Eczema, Atopy
- Trial name
- INCA (NCT02536560)
- Where
- 4 sites in Netherlands
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Agentschap NL
Atopic Dermatitis, Healthy Volunteers
A Study to Evaluate Microneedle-based Collection of Dermal Interstitial Skin Fluid in Healthy Participants and Atopic Dermatitis Participants
The purpose of this study is to evaluate microneedle-based collection of dermal interstitial skin fluid (dISF) in healthy participants and atopic dermatitis (AD) participants
- Trial name
- NCT06934980
- Testing
- Microneedle Device
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Incyte Corporation
Healthy
Clinical Evaluation of the Phototoxic Potential of Xenaderm Ointment
The product is being tested to see if exposure to light causes toxic reactions on the skin.
- Trial name
- NCT00644917
- Testing
- Xenaderm
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Healthpoint
Borderline Personality Disorder
Clinical Research Study to Evaluate Selegiline in the Treatment of Borderline Personality Disorder
Selegiline is superior to placebo in improving psychological and physical functioning in patients with Borderline Personality Disorder.
- Trial name
- NCT01912391
- Testing
- Selegiline
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mood and Anxiety Research, Inc
Atopic Dermatitis
Trial to Determine the Therapeutic Benefit of an OTC Cream on Dry, Itchy Skin of Adults and Children With Eczema
The objective of this 1 week trial is to evaluate the efficacy of an over-the-counter (OTC) 1% colloidal oatmeal skin protectant cream in adults and children with mild to moderate AD.
- Trial name
- NCT02691507
- Testing
- EpiCeram Skin Barrier Emulsion, Experimental Product 1% Colloidal Oatmeal Balm
- Where
- 2 sites in United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)