Clinical trials: Dermatitis
Healthy
Evaluation of Tetrix Cream in the Healing of Injured Skin in Subjects With Contact Dermatitis
To determine if Tetrix Cream,, when applied to the skin lesions on patients with contact dermatitis, slows or interferes with the healing of the lesions.
- Trial name
- NCT00643214
- Testing
- Tetrix
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Coria Laboratories, Ltd.
Contact Dermatitis, Contact Dermatitis Irritant
Testing an Intervention in Irritative Contact Dermatitis
An eczematous reaction is an inflammatory intolerance response of the skin. In acute phase the reaction is characterized by erythema and blistering while in the chronic phase it presents as dryness, itchiness and lichenification.
- Trial name
- NCT06189144
- Testing
- Emollient cream treatment, no treatment
- Where
- Croatia
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Split, School of Medicine
Atopic Dermatitis Eczema
Sleep & Quality of Life Evaluation of Patients With Atopic Dermatitis Based on E-diary on a Smartphone Application and Actigraphy
Atopic dermatitis is a chronic disease with a high impact on patient's quality of life. Nocturnal pruritus is one of the main symptoms affecting quality of life.
- Trial name
- ACTISLEEP (NCT03090178)
- Testing
- electronic-Patient Report Outcome and wear of a wristband actigraph
- Where
- France
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Ad scientiam
Skin Photoaging, Inflammation and Skin Pathogenic Bacteria
The Effect of Pomegranate on Aging and Inflammation of the Skin
The purpose of this study is to determine the efficacy of pomegranate extract and pomegranate juice on skin inflammation and aging.
- Trial name
- PomSkin (NCT02258776)
- Testing
- Pomegranate Extract, Pomegranate Juice
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Healthy Volunteers
A Study Evaluating Relative Bioavailability of an Oral Suspension of Abrocitinib and Effect of an Acid Reducing Agent on the Bioavailability of Abrocitinib and Assessing the Taste of Abrocitinib Oral Formulations.
This study consists of 2 parts: Part A is to estimate the relative bioavailability of a single 200 mg dose of abrocitinib oral suspension (Test formulation) compared to the commercial abrocitinib tablet (200 mg) (Reference…
- Trial name
- NCT04903093
- Testing
- Abrocitinib tablet, Abrocitinib Suspension F1, Abrocitinib Suspension F2
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Pfizer
Allergic Conditions
Primary Prevention of Allergic Disease in Early Child by Lactobacillus Reuteri
An altered microbial exposure may be partly responsible for the increase of allergic diseases in populations with a western lifestyle.
- Trial name
- NCT01285830
- Testing
- Lactobacillus reuteri
- Where
- 3 sites in Sweden
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- Linkoeping University
Ultraviolet Rays, Immunosuppression
Effect of RANKL Inhibition on UV-induced Immunosuppression
Ultraviolet (UV) light is part of normal sunlight and has many effects on human skin and health. One of the harmful effects of long-term UV light exposure is that it can cause skin cancer.
- Conditions
- Ultraviolet Rays, Immunosuppression, Hypersensitivity, Delayed, Immune Tolerance/Drug Effects
- Trial name
- NCT01978483
- Testing
- Denosumab, UVB exposure, Diphenylcyclopropenone
- Where
- Canada
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Innovaderm Research Inc.
Atopic Dermatitis
Identification of Epidermal Signatures in Patients With Atopic Dermatitis
Atopic dermatitis is a skin disorder with an itchy, red skin rash. This may be because certain proteins are increased in the skin of AD patients.
- Trial name
- NCT02680405
- Testing
- Skin Biopsy, Skin tape stripping, Blood draw
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Jewish Health
Chronic Spontaneous Urticaria (CSU), Hidradenitis Suppurativa (HS)
SKIN Disease Profiling by an Exploratory, pRospective, Biomarker Study in dermatoloGY Practice (SKINERGY)
The goal of this observational study is to comprehensively profile six immune-mediated inflammatory diseases, including atopic dermatitis (AD), plaque psoriasis (PSO), hidradenitis suppurativa (HS), cutaneous T-cell lymphoma…
- Conditions
- Chronic Spontaneous Urticaria (CSU), Hidradenitis Suppurativa (HS), Psoriasis (PsO), Atopic Dermatitis (AD)
- Trial name
- SKINERGY (NCT07021495)
- Where
- 8 sites in Netherlands
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Atopic Dermatitis, Acne
Electrochemistry Measurement of Skin Hydration Parameters
To date measuring the effect of dermocosmetic products on the main identified factors of aging and alteration of the skin barrier is based on invasive and expensive experiments.
- Conditions
- Atopic Dermatitis, Acne, Skin Electrochemistry
- Trial name
- SKINBIOSENSE (NCT05071456)
- Testing
- Collects of skin's hydration
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Contact Dermatitis
DermAI to Evaluate Human Factor of Testing
The purpose of this research is to improve how well remote patch allergy testing works and make sure they are easy and practical for people to use from home.
- Trial name
- NCT06387472
- Testing
- AI algorithm to evaluate photographs of skin test patch regions, Allergen Patch
- Where
- United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Lichen Sclerosus, Lichen Planus
Diagnostic Accuracy of "Three Rings Vulvoscopy" for Detection of Vulvar Dermatosis
The objective of the study was to determine sensitivity, specificity and diagnostic accuracy of "Three Rings Vulvoscopy" for detection of vulvar dermatosis using histopathology as the reference standard.
- Conditions
- Lichen Sclerosus, Lichen Planus, Lichen Simplex Chronicus, Vulvodynia
- Trial name
- DATRIV (NCT02732145)
- Testing
- "Three Rings Vulvoscopy" (TRIV), Histopathology
- Where
- Croatia
- Volunteers
- 328 people, healthy volunteers welcome
- Sponsor
- Ginekološka Poliklinika Dr. Vesna Harni
Atopic Dermatitis
Treatment of Nighttime Pruritus in Atopic Dermatitis
This study will look at melatonin vs. first generation antihistamine vs. placebo in improving nighttime itching in children with atopic dermatitis.
- Trial name
- NCT03688464
- Testing
- Melatonin, Diphenhydramine
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Nebraska
Atopic Dermatitis
Evaluation to Assess the Long Term Safety of Tacrolimus Ointment for Atopic Dermatitis
To assess the long-term safety of tacrolimus ointment
- Trial name
- NCT00368719
- Testing
- Tacrolimus
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Davis
Atopic Dermatitis
Prospective, Randomized, Double Blind Comparative Study on the Use of Two Creams in Xerosis Atopic Probands
Atopic dermatitis (AD), a chronic and relapsing inflammatory skin disease, is associated with elevated IgE levels and Th2 responses.
- Trial name
- NCT00509535
- Testing
- vitreoscilla filiformis cream
- Where
- Germany
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- L'Oreal
Dermatitis, Atopic
Study of Commercial and Phase 3 of PF-04965842 Formulations, Estimation of Effect of Food on Commercial Formulation
Part A To measure and compare the amount of study drug in the blood after a single 200 mg dose of study drug given as the commercial tablet formulation and the Phase 3 tablet formulation under fasting conditions To measure and…
- Trial name
- NCT04065633
- Testing
- P3-Fast, Comm-Fast, Vari-Fast
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Pfizer
Irritant Contact Dermatitis
Regional Differences of Cutaneous Irritation and Its Effect on Skin Barrier Recovery
Irritant contact dermatitis induced by sodium lauryl sulphate (SLS) is often used as a model for testing efficacy of various topical preparations.
- Trial name
- NCT03231813
- Testing
- Sodium lauryl sulphate induced irritation, Emollient, moisturizing cream
- Where
- Croatia
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Split, School of Medicine
Atopic Dermatitis
Safety and Tolerability of BSI-045B in Healthy Adult Subjects and Patients With Atopic Dermatitis
This randomized, double-blind, single center, placebo-controlled, phase 1 single ascending dose (SAD)/multiple ascending dose (MAD) study is designed to assess the safety, tolerability, PK, activity, immunogenicity, and PD of…
- Trial name
- NCT05114889
- Testing
- BSI-045B
- Where
- Australia
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Biosion, Inc.
Diaper Rash
Comparison of Barrier Products in the Prevention of Incontinence-associated Dermatitis in Hospitalized Elderly
In clinical practice, there are a large number of patients hospitalized with Incontinence-Associated Dermatitis. Studies are needed to determine the effectiveness of products available for disease prevention.
- Trial name
- NCT03309059
- Testing
- water and soap, zinc oxide, Non-Irritant Barrier Film
- Where
- Brazil
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Colic, Infantile, Milk Allergy, Cow's
Validation Of A Parent Administered Symptom Score For Unsettled Infants (Every Baby is UnIQue)
It's common for infants to be unsettled, especially in the first few months of life. While this is often normal, persistent symptoms can be stressful for families.
- Conditions
- Colic, Infantile, Milk Allergy, Cow's, Gastro Oesophageal Reflux Disease, Atopic Dermatitis (Eczema)
- Trial name
- NCT07121062
- Testing
- Online parent administered questionnaire
- Where
- United Kingdom
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust