Clinical trials: Dermatitis Atopic
Dermatitis, Atopic
Study to Investigate the Efficacy and Safety of Dupilumab Administered With Topical Corticosteroids (TCS) in Participants ≥6 to <12 Years With Severe Atopic Dermatitis (AD)
The main objective of the trial is to demonstrate the efficacy of dupilumab administered concomitantly with topical corticosteroids (TCS) in participants ≥6 years to <12 years of age with severe atopic dermatitis (AD).
- Trial name
- NCT03345914
- Testing
- Dupilumab, Background Treatment: Topical Corticosteroids, Background Treatment: Moisturizers
- Where
- 61 sites in United States, Canada and 4 more
- Volunteers
- 367 people
- Sponsor
- Regeneron Pharmaceuticals
Atopic Dermatitis
Ophthalmological Adverse Events of Tralokinumab in AD
Atopic dermatitis (AD) is a skin disease characterised by xerosis, pruritus and erythematous plaques. It is common in children (10 to 20%) with an increasing prevalence (multiplied by 2 in 20 years) and begins to develop at 3…
- Trial name
- TRALO-Oeil (NCT05682976)
- Where
- 11 sites in France
- Volunteers
- 100 people
- Sponsor
- Nantes University Hospital
Neonatal Jaundice, Atopic Dermatitis
Skin Care Strategies for Neonatal Jaundice Phototherapy to Prevent Atopic Dermatitis in Moderate and Severe Infants
Atopic Dermatitis (AD) is a common chronic, recurrent, and inflammatory skin disease in children. The incidence of moderate to severe AD in infants aged 1-12 months in our country is as high as 25.41%, which is related to…
- Trial name
- NCT05178433
- Testing
- Use baby moisturizers by NeoChine
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Shanghai First Maternity and Infant Hospital
Eczema, Atopic Dermatitis
Studies of Skin Microbes in Healthy People and in People With Skin Conditions
This study will examine microbes (e.g., bacteria, fungi, viruses) that live on human skin and how microbes contribute to health and disease.
- Trial name
- NCT00605878
- Where
- United States
- Volunteers
- 530 people, healthy volunteers welcome
- Sponsor
- National Human Genome Research Institute (NHGRI)
Dermatitis, Atopic Dermatitis
Efficacy and Safety Study of Apremilast in Subjects With Moderate to Severe Atopic Dermatitis
A study to evaluate the efficacy and safety of apremilast (CC-10004) in subjects with moderate to severe atopic dermatitis
- Trial name
- NCT02087943
- Testing
- Apremilast
- Where
- 31 sites in United States, Canada and 1 more
- Volunteers
- 191 people
- Sponsor
- Amgen
Atopic Dermatitis
Assessment of the Effect of Coconut and Sunflower Seed Oil Derived Isosorbide Diseters and Colloidial Oatmeal
The goal of this study is to compare coconut oil and sunflower seed oil derived isosorbide disesters and colloidal oatmeal, and observe their effect on pediatric atopic dermatitis among males and females aged 2-17.
- Trial name
- NCT05688735
- Testing
- Isosorbide Diester Moisturizer, Control Moisturizer
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Dermatitis, Atopic, Eczema, Atopic
Long-term Safety of Protopic in Atopic Eczema
Patients who have participated in previous studies with Tacrolimus ointment for atopic eczema are entitled to enter this four-year follow study to investigate the safety of treatment with Tacrolimus ointment 0.1%
- Trial name
- NCT00560378
- Testing
- Tacrolimus ointment 0.1%
- Where
- 41 sites in Belgium, Denmark and 10 more
- Volunteers
- 789 people
- Sponsor
- Astellas Pharma Inc
Atopic Dermatitis, Food Allergy in Children
Preventing Atopic Dermatitis and ALLergies in Children
The primary objective is of the PreventADALL study is to test if primary prevention of allergic diseases is possible by simple and low cost strategies, and secondary to asses the impact of xenobiotic exposure and microbiota in…
- Conditions
- Atopic Dermatitis, Food Allergy in Children, Asthma, Rhinitis, Allergic
- Trial name
- PreventADALL (NCT02449850)
- Testing
- Food intervention, Skin care
- Where
- Norway
- Volunteers
- 2,701 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Atopic Dermatitis, Allergy Pollen
Study to Assess the Effect of "Eucerin AtopiControl" on Dermal Symptoms in Patients With Atopic Dermatitis
The objective of this study is to assess the effect of 'Eucerin AtopiControl LOTION' and 'Eucerin AtopiControl facial cream' on dermal symptoms in patients with Atopic Dermatitis (AD) after two 4 h challenges with grass pollen on…
- Trial name
- NCT03315611
- Testing
- 'Eucerin AtopiControl Lotion' (for the body), Allergen challenge chamber
- Where
- Germany
- Volunteers
- 23 people
- Sponsor
- Fraunhofer-Institute of Toxicology and Experimental Medicine
Atopic Dermatitis (AD)
Tolerance Evaluation of a Nighttime Moisturizing Balm on Babies and Adults With Eczema
The purpose of this 14-day, two phase clinical study is to test the tolerance of a new over-the-counter moisturizing balm on subjects with eczema.
- Trial name
- NCT02357940
- Testing
- Experimental Product
- Where
- 2 sites in United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Atopic Dermatitis
Clinical Trial to Evaluate the Effect of a Probiotic Mixture in the Treatment of Atopic Dermatitis in Children
A prospective case-control multicentric pilot study of 12 weeks duration to evaluate the effect of a probiotic mixture in the treatment of atopic dermatitis in children from 0 to 3 years old, by measuring the severity of the…
- Trial name
- NCT05443490
- Testing
- Probiotic mixture with three bacterial strains with maltodextrin as a carrier.
- Where
- 3 sites in Bolivia, Costa Rica and 1 more
- Volunteers
- 4 people
- Sponsor
- Bionou Research, S.L.
Atopic Dermatitis, Eczema
The Utility of Functionally Relevant Signature Genes in Assessing the Clinical Outcomes of Dupilumab Treatment
The utility of functionally relevant signature genes in assessing the clinical outcomes of dupilumab treatment in the adult onset atopic dermatitis
- Trial name
- NCT04358224
- Testing
- Dupilumab Prefilled Syringe
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Jonathan A. Bernstein, MD
Atopic Dermatitis
Methodological Study of the Effect of a Lotion Containing Nature Based Microbial Extract on Atopic Skin
The purpose of the study is to test the selected methods and to explore the effect of nature-based exposure on immunological biomarkers and the condition of atopic skin.
- Trial name
- NCT06499766
- Testing
- Biodiversity intervention by inactivated microbial extract
- Where
- Finland
- Volunteers
- 12 people
- Sponsor
- Uute Scientific Oy
Atopic Dermatitis, Eczema Herpeticum
Identifying Risk Factors for Eczema Herpeticum in Individuals With Atopic Dermatitis
Atopic Dermatitis (AD), also known as eczema, is a skin disease that causes the skin to be hot, dry and scaly, and have severe itching. There are different kinds of eczema.
- Trial name
- NCT00438022
- Where
- Germany
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Atopic Dermatitis, Eczema-Prone Skin
Skin Efficacy and Tolerability of a Cosmetic Product Combination Over 3 Months in Subjects With Atopic Eczema
The aim of this exploratory study is to investigate the short- and long-term efficacy and tolerability of a cosmetic product combination consisting of a body lotion and an intensive care product in subjects with atopic eczema…
- Trial name
- AtoCare-OS (NCT05790083)
- Testing
- Body Lotion and Intensive Care
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bionorica SE
Atopic Dermatitis
Randomized Placebo Controlled Study to Determine Safety, Pharmacodynamics and Efficacy of ILV-094 in Atopic Dermatitis
Atopic dermatitis (AD) is a common inflammatory skin disorder that adversely affects most aspects of everyday life in majority of patients. It has a prevalence of up to 3-4% of adults and up to 25% among children.
- Trial name
- NCT01941537
- Testing
- ILV-094
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Rockefeller University
Healthy Adults, Atopic Dermatitis
Sweat and Gas Sensor for Healthy Skin and Atopic Dermatitis
Pilot study of a wearable gas and sweat skin sensor
- Conditions
- Healthy Adults, Atopic Dermatitis, Wearables, Sweat Sensor
- Trial name
- NCT03874039
- Testing
- Gas sensor, Sweat Sensor
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Atopic Dermatitis
Real-world Experience Using Nemolizumab in the Treatment of Moderate-to-Severe Atopic Dermatitis in Adolescents & Adults
The main aim of the study is to assess real-world effectiveness of nemolizumab in Atopic Dermatitis (AD) as measured by physician assessment and patient reported outcome (PRO) in clinical practice at Month 6.
- Trial name
- RE-UNITE AD (NCT06988605)
- Where
- 108 sites in United States, Germany and 1 more
- Volunteers
- 1,000 people
- Sponsor
- Galderma R&D
Eczema, Atopic Dermatitis
Bilateral Comparison Study of Elidel 1% and Hylatopic Plus Emollient Foam for the Treatment of Subjects With Atopic Dermatitis
This is an investigator-blinded, bilateral comparison study in 30 subjects with atopic dermatitis. It is designed to assess and compare the efficacy of Elidel® (pimecrolimus) cream 1% and Hylatopic™ Plus Emollient Foam™ in…
- Trial name
- NCT01202149
- Testing
- Elidel (pimecrolimus cream, 1%) Hylatopic Plus Emollient Foam (non-medicated device)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Frankel, Amylynne, M.D.
Atopic Dermatitis
A Study Evaluating TRIV-509 in Atopic Dermatitis
The goal of this interventional study is to learn if TRIV-509 works to treat moderate to severe atopic dermatitis in adults. It will also evaluate the safety of TRIV-509.
- Trial name
- NCT07167758
- Testing
- TRIV-509
- Where
- 32 sites in United States, Bulgaria and 5 more
- Volunteers
- 95 people
- Sponsor
- Triveni Bio
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