Clinical trials: Dermatologic
Surgical Site Infection
Utility of Single-dose Oral Antibiotic Prophylaxis in Prevention of Surgical Site Infection in Dermatologic Surgery
The purpose of the study is to assess the effectiveness of a single dose of preoperative antibiotic in reducing surgical site infections in certain dermatological procedures.
- Trial name
- NCT04580472
- Testing
- Cephalexin
- Where
- United States
- Volunteers
- 574 people
- Sponsor
- Carilion Clinic
Psoriasis, Quality of Life
Assessment of Dermatologic Family Impact Scale in the Parents of Children With Psoriasis
The Dermatological Diseases Family Impact Scale (DeFIS) was developed to assess different aspects of health-related quality of life in the relatives of the patients with various skin diseases.
- Trial name
- NCT02796014
- Where
- 7 sites in Turkey (Türkiye)
- Volunteers
- 129 people
- Sponsor
- Istanbul Medeniyet University
Epidermolysis Bullosa
Study of the Nutritional, Metabolic, and Body Composition Profile in Children and Adolescents With Epidermolysis Bullosa
OBJECTIVES: I. Characterize the nutritional and metabolic profile of children and adolescents with epidermolysis bullosa. II. Determine patterns of body composition in these patients. III.
- Trial name
- NCT00004791
- Volunteers
- 15 people
- Sponsor
- National Center for Research Resources (NCRR)
Body Image, Psychological Distress
Testing a Body-functionality Intervention for Body Image in Individuals With Skin Conditions
'Expand Your Horizons', a self-help writing intervention that seeks to train individuals to focus on what their body can do (functionality) rather than what it looks like (appearance), has produced promising results in improving…
- Conditions
- Body Image, Psychological Distress, Dermatologic Disease, Quality of Life
- Trial name
- NCT04445974
- Testing
- Expand your horizons: More than my skin, Creative writing activities
- Where
- United Kingdom
- Volunteers
- 454 people
- Sponsor
- University of Sheffield
Wound Healing and Scar Quality Following Mohs Surgery and Excisional Dermatologic Surgery
Porcine Xenograft Versus Second Intention Healing
The purpose of this research study is to test whether it is better to allow patients with post- operative wounds on the legs to heal on their own without a covering or to use a porcine xenograft (skin graft that is made from pig…
- Trial name
- NCT03931746
- Testing
- Porcine xenograft
- Where
- 2 sites in United States
- Volunteers
- 14 people
- Sponsor
- Northwell Health
Edema, Dermatologic Complication
Care Bundle for Prevention of Skin Complications and Edema in Restrained Patients
Physical restraint (restraint) is defined as the restriction of a patient's free body movements and the prevention of the patient's ability to move easily by healthcare professionals using physical or mechanical devices to…
- Conditions
- Edema, Dermatologic Complication, Physical Restraints
- Trial name
- SCER-ICU (NCT07442344)
- Testing
- Evulation, Application of physical restraint material, Elevation
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Kocaeli City Hospital
Pain
Comparing the Pain Experience Between Patients Who Have and Who Have Not Undergone Dermatologic Procedures
The purpose of this study is to compare the pain experience of patients who have not had dermatologic procedures (previously "unexposed") using energy devices (lasers, radiofrequency, ultrasound, etc.) with patients who have…
- Trial name
- NCT01285947
- Testing
- Thermage, Needle Application, VBeam Laser
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Hand and Foot Skin Reaction, Colorectal Cancer Stage IV
Study on the Prevention of Dermal Toxicity Caused by Regorafenib by Traditional Chinese Medicine TDX105
this is an preventive study to evaluate the preventive effect of traditional chinese medicine TDX105 on Regorafenib induced Dermatologic Toxicities
- Trial name
- NCT05289726
- Testing
- Traditional chinese medicine TDX105
- Where
- China
- Volunteers
- 152 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Type 2 Diabetes Mellitus
Examination of Dermatologic Effects From Subcutaneous Injections of ISIS 113715
10 healthy volunteers will be enrolled to each receive two subcutaneous injections of ISIS 113715 in the abdomen on Study Day 1. Each subject will receive their two injections within a 5-minute period.
- Trial name
- NCT00365781
- Testing
- ISIS 113715
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Ionis Pharmaceuticals, Inc.
Pain, Phlebotomy
Synera Venipuncture Pain
Synera, which is a heated topical patch containing both lidocaine and tetracaine, is intended to reduce the pain associated with venipuncture and superficial dermatologic procedures by numbing the skin.
- Conditions
- Pain, Phlebotomy, Palliative Care
- Trial name
- NCT01744197
- Testing
- Synera (lidocaine 70mg/tetracaine 70mg)
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- US Oncology Research
Surgical Wound Infection
Impact of Early Post-Operative Water Exposure on Complications of Cutaneous Surgeries
Patients are often counseled to keep a surgical wound dry for 2 to 3 days. The rationale is likely to decrease the risk of infection and bleeding. However, this has never been formally studied.
- Trial name
- NCT01773694
- Testing
- Early Water Exposure
- Where
- United States
- Volunteers
- 507 people
- Sponsor
- Milton S. Hershey Medical Center
Wrinkles, Scars
Pilot Evaluation of the Cynosure Potenza™ System for Treatment of Cosmetic Dermatologic Skin Conditions
The primary objective of this pilot study is exploratory investigation evaluating the Potenza microneedle fractional radiofrequency (RF) device and may be used in combination with the Icon intense pulsed light (IPL) device.
- Conditions
- Wrinkles, Scars, Stretch Marks, Pigmentation
- Trial name
- NCT05847530
- Testing
- Potenza, Icon
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cynosure, Inc.
Cancer, Healthy
Collection and Distribution of Biospecimens for Novel Research
iSpecimen aims to create a clinical partner network of hospitals, laboratories, academic institutions, and other healthcare organizations ("institutions") capable of providing researchers and educators ("researchers") with…
- Conditions
- Cancer, Healthy, Gastrointestinal Complication, Autoimmune Diseases
- Trial name
- NCT05080907
- Testing
- Observational
- Where
- 7 sites in United States
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- iSpecimen Inc
Psoriasis
Study of Topical Calcitriol in Children With Psoriasis
OBJECTIVES: I. Determine the therapeutic efficacy and safety of topical calcitriol in children with psoriasis.
- Trial name
- NCT00006275
- Testing
- calcitriol
- Volunteers
- 20 people
- Sponsor
- National Center for Research Resources (NCRR)
Bullous Dermatoses, Psoriasis
Intradermal Tozinameran for Patients With Immune-mediated Dermatologic Diseases
This is a randomised controlled trial conducted to prove that the immunological performance of intradermal tozinameran (i.e., Pfizer-BioNTech COVID-19 vaccine) is no worse than the standard intramuscular route in patients with…
- Conditions
- Bullous Dermatoses, Psoriasis, COVID-19 Vaccines
- Trial name
- NCT05406908
- Testing
- tozinameran
- Where
- Thailand
- Volunteers
- 109 people
- Sponsor
- Mahidol University
Dermatologic Disease, Epidermolysis Bullosa
The State of Sexual Development in Children With Inherited Epidermolysis Bullosa
The aim of the study is to determine the state of sexual development in patients with inherited epidermolysis bullosa; the study is planned to include boys and girls aged 8 to 18 years with a diagnosis of epidermolysis bullosa…
- Conditions
- Dermatologic Disease, Epidermolysis Bullosa, Epidermolysis Bullosa Simplex, Epidermolysis Bullosa Dystrophica
- Trial name
- NCT05033574
- Testing
- Biochemical study of hormone levels, Ultrasound examination, Radiography of the hands
- Where
- Russia
- Volunteers
- 50 people
- Sponsor
- National Medical Research Center for Children's Health, Russian Federation
Carcinoma, Non-Small-Cell Lung
Enhanced Dermatological Care to Reduce Rash and Paronychia in Epidermal Growth Factor Receptor (EGRF)-Mutated Non-Small Cell Lung Cancer (NSCLC) Treated First-line With Amivantamab Plus Lazertinib
The purpose of this study is to evaluate whether enhanced dermatologic management can reduce incidence of grade greater than or equal to (>=) 2 dermatologic adverse events of interest (DAEIs) when compared with standard-of-care…
- Trial name
- COCOON (NCT06120140)
- Testing
- Amivantamab IV, Amivantamab SC, Lazertinib
- Where
- 93 sites in United States, Argentina and 9 more
- Volunteers
- 305 people
- Sponsor
- Janssen Research & Development, LLC
Chronic Effect of Ultraviolet Radiation on Photoaged Skin, Dermatologic Disorders
Safety Study of Bone Marrow Derived Stem Cells on Patients With Cutaneous Photoaging
The purpose of this study is to determine whether a one-time injection of allogeneic mesenchymal bone marrow cells is safe and beneficial in the treatment of photodamage on the face.
- Trial name
- NCT01771679
- Testing
- Allogeneic Mesenchymal Bone Marrow Cells
- Where
- 2 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Stemedica Cell Technologies, Inc.
Cancer, Healthy
Collection and Distribution of Biospecimens for Novel Research Uses
iSpecimen aims to create a clinical partner network of hospitals, laboratories, academic institutions, and other healthcare organizations ("institutions") capable of providing researchers and educators ("researchers") with…
- Conditions
- Cancer, Healthy, Gastrointestinal Complication, Autoimmune Diseases
- Trial name
- NCT03848962
- Where
- 2 sites in United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- iSpecimen Inc
Assessment, Lipedema
Physical Therapy in Lipedema Surgery
The goal of this observational study or clinical trial is to know evaluate the effects of a modified Complete Decongestive Therapy protocol using the Godoy Method in the postoperative period following lipedema surgery.
- Conditions
- Assessment, Lipedema, Vascular Diseases, Dermatologic Complication
- Trial name
- NCT05966779
- Testing
- modified CDT physical therapy protocol, based on Godoy's Method
- Where
- Spain
- Volunteers
- 293 people
- Sponsor
- University of Alcala