Clinical trials: Dermatologic
Epidermolysis Bullosa
Phase I Study of Isotretinoin in Patients With Recessive Dystrophic Epidermolysis Bullosa
OBJECTIVES: I. Determine the safety of isotretinoin in patients with recessive dystrophic epidermolysis bullosa.
- Trial name
- NCT00014729
- Testing
- isotretinoin
- Volunteers
- 20 people
- Sponsor
- University of North Carolina
Dermatologic Disease
Effect of Vitamin D Injection on Hypertrophic Scars and Keloids
Scars and keloids cause patients severe morbidity and psychological distress. Hypertrophic scars rise above the skin but stay within the scar boundaries, while keloids expand.
- Trial name
- NCT06301178
- Testing
- Cholecalciferol
- Where
- Egypt
- Volunteers
- 35 people
- Sponsor
- Mostafa Bahaa
Dermatologic Disease
Addressing Inequity in Dermatology
The objectives of this study are to understand the variation in dermatoses presenting in individuals from different ancestry backgrounds. This will be conducted at multiple NHS hospitals in England.
- Trial name
- NCT06056648
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- University of Manchester
Surgical Site Infections
PHMB-based Antiseptic Use in Full-thickness Surgical Wounds
To study the effect of applying a PHMB-based antiseptic solution to tie-over dressings in full-thickness surgical wounds in dermatologic surgery in order to minimise the development of surgical site infections.
- Trial name
- NCT02253069
- Testing
- Applying Prontosan antiseptic solution to tie-over dressings
- Where
- Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Region Skane
Dermatologic Diseases
Role of Angiogenesis in Dermatologic Diseases: A Potential Therapeutic Target
The researchers believe that pro-angiogenic factors are upregulated in a wide range of dermatologic diseases, including port wine stains, hemangiomas, angiofibromas, Kaposi's sarcoma, angiosarcoma, scars, rosacea, and psoriasis.
- Trial name
- NCT00842283
- Testing
- skin tissue sample
- Where
- 2 sites in United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Dermatologic Complications, Pain
Scrambler Therapy in Treating Chronic Pain in Patients With Rash From Varicella Zoster Virus Infection
This pilot clinical trial studies how well scrambler therapy works treating chronic pain in patients with rash from varicella zoster virus infection.
- Conditions
- Dermatologic Complications, Pain, Viral Infection
- Trial name
- NCT01347736
- Testing
- scrambler therapy, questionnaire administration, dermatologic complications management/prevention
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Mayo Clinic
Medical Adhesive Allergy, Dermatologic Conditions
Foam Tape Allergy a Sticky Situation
Foam tape is commonly used in the emergency department as a dressing over chest tubes owing to its occlusive and compressible properties.
- Conditions
- Medical Adhesive Allergy, Dermatologic Conditions, Dermatologic Lesions
- Trial name
- NCT06059417
- Testing
- 2x2 inch piece of 3M microfoam adhesive
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CHRISTUS Health
Dermatologic Disorders
Bioequivalence of Topical Acyclovir in Healthy Volunteers
The overall aim of this clinical study is to investigate the ability of dermal open flow microperfusion to assess bioequivalence and non-bioequivalence of acyclovir formulations in the skin of healthy volunteers.
- Trial name
- FDA_BE1 (NCT02711267)
- Testing
- 5% Zovirax® cream, 5% Aciclostad cream, 5% Aciclovir cream 1A Pharma
- Where
- Austria
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Skin Regeneration After Dermatological Facial Procedure With Fractional CO2 Laser
Clinical Trial to Evaluate Safety and Efficacy of a Facial and Lip Moisturizer in Adult Subjects Undergoing a Facial Dermatologic Procedure With Fractional CO2 Laser
This is study aims to evaluate the topical safety (tolerability/acceptability) and efficacy of TH Facial Moisturizer and TH Lip Moisturizer Investigational products after 21 ± 2 days of use under normal conditions on the…
- Trial name
- NCT05272787
- Testing
- TH Facial Moisturizer, TH Lip Moisturizer, Facial Moisturizer B (Control)
- Where
- Brazil
- Volunteers
- 35 people
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Anesthetics, Local
Split Face Study of the Duration of Local Anesthetics
This is a research study to compare how long injectable pain medications (anesthetics) commonly used in dermatologic surgery are effective for.
- Trial name
- NCT05767749
- Testing
- lidocaine + epinephrine 1:100,000, Ropivacaine 0.5% Injectable Solution, Bupivacaine 0.5% Injectable Solution
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Breast Cancer, Dermatologic Complications
Mometasone Furoate in Preventing Radiation Dermatitis in Patients Undergoing Radiation Therapy to the Breast or Chest Wall for Invasive Breast Cancer or Ductal Carcinoma in Situ
RATIONALE: Steroid therapy, such as mometasone furoate, may prevent radiation dermatitis caused by radiation therapy. It is not yet known whether mometasone furoate is more effective than a placebo in preventing radiation…
- Conditions
- Breast Cancer, Dermatologic Complications, Radiation Toxicity, Skin Reactions Secondary to Radiation Therapy
- Trial name
- NCT00438659
- Testing
- mometasone furoate
- Where
- 189 sites in United States
- Volunteers
- 176 people
- Sponsor
- North Central Cancer Treatment Group
Skin Diseases
Observational Study to Assess Safety and Utility Pattern of Topical Steroids
To assess incidence of adverse drug reactions and use pattern of topical steroids among patients who are prescribed or purchase over the counter (OTC) topical steroids for skin conditions in Korea
- Trial name
- NCT02377557
- Testing
- Topical Steroids
- Where
- South Korea
- Volunteers
- 1,175 people
- Sponsor
- Hanyang University
Pain
Safety Study of S-Caine Peel (Skin Numbing Cream) Before a Painful Dermatologic Procedure in Children
The purpose of this study is to evaluate the safety of one treatment of S-Caine™ Peel (skin numbing cream) applied on healthy skin before a painful dermatologic procedure in children.
- Trial name
- NCT00107822
- Testing
- S-Caine™ Peel (lidocaine and tetracaine cream 7%/7%)
- Where
- 3 sites in United States
- Volunteers
- 80 people
- Sponsor
- ZARS Pharma Inc.
Dermatologic Conditions
Teledermatology Versus Usual Care on Delay Before Diagnosis and Treatment of Dermatologic Conditions
In France, there is usually a long delay (approximately 6 weeks) before a general practitioner can obtain a specialized advice by dermatologists for diagnosis of "unusual" dermatologic conditions of their patients.
- Trial name
- TELEDERMATO (NCT02122432)
- Testing
- Teledermatology
- Where
- France
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- University Paris 7 - Denis Diderot
Vitiligo, Pediatric ALL
Efficacy and Safety of 308-nm Excimer Lamp Combined With Tacrolimus vs Tacrolimus as Monotherapy in Treating Vitiligo on Children
Vitiligo is a auto immune that impact 2% of the global population, regardless from the phototype. Even though it affects patients in a physical way through loss of pigmentation, it is also impacting them on a mental/emotional…
- Conditions
- Vitiligo, Pediatric ALL, Dermatologic Disease, Autoimmune Diseases
- Trial name
- NCT06035614
- Testing
- exciplex, Tacrolimus ointment
- Where
- Jordan
- Volunteers
- 50 people
- Sponsor
- Clarteis
Actinic Keratosis
Study of Reformulated Levulan Kerastick Plus PDT for Actinic Keratosis on Upper Extremities
This Phase 3, randomized, multi-center, evaluator-blind, vehicle-controlled study evaluates the efficacy and safety of reformulated Levulan Kerastick (aminolevulinic acid HCl 20%) combined with photodynamic therapy (PDT) for…
- Trial name
- NCT07144852
- Testing
- Reformulated Levulan Kerastick containing aminolevulinic acid hydrochloride (ALA HCl), 20%, Vehicle, Blue Light Photodynamic Therapy Illuminator device, BLU-U® model 4170E.
- Where
- 20 sites in United States
- Volunteers
- 260 people
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Non Small Cell Lung Cancer (NSCLC)
Study Of Dacomitinib (PF-00299804) In Advanced NSCLC Patients (Post Chemo Or Select First Line) To Evaluate Prophylactic Intervention On Derm And GI AEs And PRO
To assess the impact of prophylactic treatment on the incidence of adverse events in advanced NSCLC patients (post chemotherapy) treated with dacomitinib daily as a single agent.
- Trial name
- ARCHER 1042 (NCT01465802)
- Testing
- Dacomitinib, Doxycycline, Probiotic
- Where
- 81 sites in United States, South Korea
- Volunteers
- 236 people
- Sponsor
- Pfizer
Sleep Disorder
Sleep Disturbances in Dermatology Patients
This study is to investigate sleep disorders in patients with dermatologic diseases by taking into consideration dermatologic (itch, pain) and non- dermatologic (medication, depression) factors.
- Trial name
- NCT03903263
- Testing
- survey on sleep disorders
- Where
- Switzerland
- Volunteers
- 624 people
- Sponsor
- University Hospital, Basel, Switzerland
Dermatologic Disease, Depression
Investigating Compassion-Based Guided Self-Help for Depression in People With Skin Conditions
The study aims to explore whether an online compassion-based guided self-help intervention is perceived as acceptable to people with heterogeneous skin conditions, in terms of retention rates and explicit feedback.
- Trial name
- NCT04132973
- Testing
- Compassion for Skin Conditions
- Where
- United Kingdom
- Volunteers
- 34 people
- Sponsor
- University of Sheffield
Suture Dermatologic, Surgery
Comparison of Cosmetic Outcomes of Straight Line and W-plasty Techniques for Linear Wound Closure
The purpose of this study is to compare the cosmetic outcome of traditional straight-line (SL) linear closure to that of W plasty (a type of geometric broken-line cutaneous closure technique) for closure of post-auricular wounds…
- Conditions
- Suture Dermatologic, Surgery, Cosmetic Outcome
- Trial name
- NCT05074199
- Testing
- W-plasty/Linear closure
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, Davis