Clinical trials: Dermatologic
Rheumatic, Dermatologic Disorders
Yellow Fever Vaccination Under Low Dose Methotrexate Therapy
Travelers (n = 30, 15 taking low-dose methotrexate (MTX), 15 healthy controls (HC), seeking travel advice in one of the following Swiss Travel Centers (Aarau, Basel, Bern, Geneva, Lausanne, Zurich) and who have an indication for…
- Trial name
- MTX_YF (NCT02383680)
- Testing
- Yellow Fever Vaccination
- Where
- 6 sites in Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Medication Adherence
Perspectives on Prophylactic Antibiotic Use in Dermatologic Surgery
This is a prospective, multi-center observational survey study to uncover how antibiotic differences can influence utilization decisions.
- Trial name
- NCT04150523
- Testing
- Survey
- Where
- 8 sites in United States
- Volunteers
- 338 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Pain, Anxiety
Patient Comfort During Dermatologic Procedures
The goal of this study is to find the effect of holding a patient's hand on anxiety and pain during dermatologic procedures.
- Trial name
- NCT02816996
- Testing
- Hand-holding, Stress Ball
- Where
- United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Atopic Dermatitis, Atopic
A Phase 2b Study of the Effects of Camoteskimab in Adults With Moderate-to-Severe Atopic Dermatitis
This is a phase 2b, multicenter, randomized, double-blind, placebo-controlled study.
- Conditions
- Atopic Dermatitis, Atopic, Dermatitis, Dermatitis, Atopic
- Trial name
- NCT07599813
- Testing
- Camoteskimab
- Where
- 85 sites in United States, Bulgaria and 6 more
- Volunteers
- 280 people
- Sponsor
- Apollo Therapeutics Ltd
Vernal Keratoconjunctivitis, Atopic Keratoconjunctivitis
Dermatologic Tacrolimus Ointment on Eyelids in the Treatment of Refractory Vernal Keratoconjunctivitis and Atopic Keratoconjunctivitis
To evaluate the therapeutic effects of dermatologic tacrolimus ointment on eyelids to treat refractory vernal keratoconjunctivitis and atopic keratoconjunctivitis.
- Conditions
- Vernal Keratoconjunctivitis, Atopic Keratoconjunctivitis, Tacrolimus
- Trial name
- NCT03557203
- Where
- Taiwan
- Volunteers
- 10 people
- Sponsor
- National Taiwan University Hospital
Psoriasis
A Study to Investigate Interchangeability of ABP 654 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis
The purpose of the study is to evaluate pharmacokinetic similarity, efficacy, safety and immunogenicity of multiple switches between ustekinumab and ABP 654 compared with continued use of ustekinumab in participants with moderate…
- Trial name
- NCT04761627
- Testing
- Ustekinumab, ABP 654
- Where
- 88 sites in United States, Canada and 6 more
- Volunteers
- 494 people
- Sponsor
- Amgen
Dermatologic Complications, Unspecified Adult Solid Tumor, Protocol Specific
Topical Sunscreen in Preventing Skin Rash in Patients Receiving Drugs Such as Erlotinib or Cetuximab for Cancer
RATIONALE: Topical sunscreen may be effective in preventing skin rash caused by treatment with drugs such as erlotinib or cetuximab.
- Trial name
- NCT00362986
- Testing
- sunscreen
- Where
- 208 sites in United States
- Volunteers
- 116 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Respiratory Disease, Otorhinolaryngologic Diseases
Impact of Spa Treatments on the Consumption of Care in Children
Children represent 1.2% of the spa population in France. Spa treatments, including climatic stays, are mainly prescribed for children in the context of respiratory, otorhinolaryngology and dermatological conditions.
- Conditions
- Respiratory Disease, Otorhinolaryngologic Diseases, Dermatologic Disease
- Trial name
- PEDIATHERM (NCT03931226)
- Testing
- Drug consumption
- Where
- France
- Volunteers
- 8,372 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Vitiligo, Atopic Dermatitis
An Observational Study of Patients With Dermatologic Disease
TARGET-DERM+ is an observational research study to conduct a comprehensive review of outcomes for patients with dermatologic disease (DD) and providers who treat these patients.
- Conditions
- Vitiligo, Atopic Dermatitis, Alopecia Areata, Hidradenitis Suppurativa (HS)
- Trial name
- TARGET-DERM+ (NCT07748169)
- Where
- United States
- Volunteers
- 2,000,000 people
- Sponsor
- Target PharmaSolutions, Inc.
Psoriasis
Study of Topical Calcitriol or Oral Calcitriol in Patients With Psoriasis
OBJECTIVES: I. Evaluate the long term safety and efficacy of orally administered calcitriol in patients with at least 5% of their body covered with psoriasis. II.
- Trial name
- NCT00004468
- Testing
- calcitriol
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Skin Cancer Face, Quality of Life
Buddy Relationships in DermatoloGic Excisions for Skin Cancer
More than 5 million skin cancer surgeries are performed each year in the United States with 80% of tumors appearing on the head and neck.
- Conditions
- Skin Cancer Face, Quality of Life, Surgical Wound, Peer Mentorship
- Trial name
- BRIDGES (NCT04036344)
- Testing
- Peer Mentorship Program
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Hidradenitis Suppurativa
Defects of Keratinocytes Function in Dermatologic Patients
NOTCH signaling in the skin exerts a pivotal role in the regulation of normal keratinocytes turnover by mediating the balance between proliferation, differentiation, apoptosis and autophagic flux progression.
- Trial name
- NCT06324552
- Where
- 15 sites in Austria, Belgium and 4 more
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- IRCCS Burlo Garofolo
Drug-Related Side Effects and Adverse Reactions, Epidermal Growth Factor
Therapeutic Effect of EGF Cream for Cutaneous Adverse Event of EGFR Inhibitors
The purpose of this study is to evaluate the therapeutic efficacy of topical EGF cream for dermatologic adverse events related to EGFR inhibitors.
- Trial name
- NCT03047863
- Testing
- Repair Control EGF®, Cream without rhEGF
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- The Catholic University of Korea
Dermatologic Conditions
Prospective Clinical Study to Assess Safety and to Collect Data on Radiofrequency Microneedling Device(s) For the Purpose of Evaluating Treatment on Skin
The goal of the Radiofrequency microneedling devices (Potenza and Morpheus) used in this study is to collect clinical data for dermatologic conditions in which electrocoagulation and hemostasis is a viable mechanism for means of…
- Trial name
- NCT06023303
- Testing
- Potenza, Morpheus
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Cynosure, Inc.
Lean Muscle Development, Muscular Endurance
A Clinical Trial to Evaluate the Effects of a Powder Supplement in Supporting Lean Muscle Development, Hormone-Related Wellness, Digestive Comfort, Dermatologic Health, and Overall Wellness
This study will evaluate the effects of Clean Nutra's Shelf Builder Women's Creatine Powder on lean muscle development, hormone-related wellness, digestive comfort, dermatological health, and overall wellness.
- Conditions
- Lean Muscle Development, Muscular Endurance, Hormone-Related Wellness, Digestive Comfort
- Trial name
- NCT07766395
- Testing
- Shelf Builder Women's Creatine Powder
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Clean Nutraceuticals
Venomous Snakebites, Local Anesthesia
Subcutaneous Injection of Large Volumes of Tumescent Lidocaine and Epinephrine by Laypersons
This research is intended to show that it is safe and not difficult for nearly anyone to inject at least 125ml of a dilute solution of tumescent lidocaine and epinephrine (TLE), where a TLE solution consists of lidocaine (1gm/L)…
- Conditions
- Venomous Snakebites, Local Anesthesia, Painless Injection, Regional Anesthesia
- Trial name
- TLE-RCT (NCT04733781)
- Testing
- Tumescent Lidocaine and Epinephrine
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Jeffrey Alan Klein, MD
Dermatological Disorders
Assessment of Knowledge, Attitude and Practice of Primary Care Doctors Towards Common Dermatologic Conditions in Sudan
The goal of this observational study is to assess the knowledge, attitude, and practice of primary care physicians regarding the common dermatologic conditions in Sudan.
- Trial name
- NCT06664489
- Where
- Sudan
- Volunteers
- 178 people
- Sponsor
- Afifa Muhammad Alameen Khalifa Alshaykh
Local Anaesthetic Complication, Pain
Kinetic Anesthesia Device Study
Patients experience discomfort from lidocaine injections. Vibrating kinetic anesthesia devices (KAD) have been shown to reduce pain of injections in dentistry, pediatrics, and dermatology, though no studies of lidocaine…
- Trial name
- NCT03344510
- Testing
- Kinetic Anesthesia Device, Control
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Skin Toxicity
Novel Skin Care for Chemotherapy- Related Dermatologic Toxicities
Notwithstanding the continuous progress in cancer treatment, patients with cancer still have to cope with quality of life (QoL) - impairing complications.
- Trial name
- ChemoSkin (NCT04929847)
- Testing
- Self-prepared emollient
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Jessa Hospital
Dermatologic Disorders, Disorder of Cholesterol Metabolism
Confocal Raman Spectroscopy: in Vivo Measurement of Physiological Skin Parameters
The purpose of this study is to I. determine several skin parameters, for example natural moisturizing factor (NMF) and cholesterol, with Raman spectroscopy in vivo and II.
- Trial name
- NCT02854475
- Testing
- Venous blood collection, Raman spectroscopy
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Vienna