Clinical trials: Dermatologic Diseases
Colostomy, Ileostomy
User Evaluation of the Peristomal Skin Condition in Ostomates Using ConvaTec Moldable Technology™
The primary aim of this study is to demonstrate the maintenance of healthy peri-stomal skin over a two month period in subjects who use ConvaTec Moldable Technology™ Skin Barriers as part of their standard protocol of care…
- Conditions
- Colostomy, Ileostomy, Urostomy
- Trial name
- OSMOSE (NCT02499588)
- Testing
- Esteem Plus with ConvaTec Moldable Technology, Natura with ConvaTec Moldable Technology, Natura Accordion with ConvaTec Moldable Technology
- Where
- Poland
- Volunteers
- 600 people
- Sponsor
- ConvaTec Inc.
Atopic Dermatitis
Evaluate Efficacy, PK, and Safety of FB825 in Adults With Atopic Dermatitis
The study aims to evaluate the efficacy, improvement from baseline in Eczema Area and Severity Index (EASI) score, of multiple intravenous (IV) doses of FB825 in subjects with atopic dermatitis
- Trial name
- NCT04413942
- Testing
- FB825
- Where
- 18 sites in United States
- Volunteers
- 99 people
- Sponsor
- Oneness Biotech Co., Ltd.
Melanoma (Skin)
Biological Therapy in Treating Patients With Metastatic Melanoma
RATIONALE: Biological therapies use different ways to stimulate the immune system and stop cancer cells from growing. PURPOSE: Phase I/II trial to study the effectiveness of biological therapy in treating patients who have…
- Trial name
- NCT00002786
- Testing
- aldesleukin, therapeutic tumor infiltrating lymphocytes
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Fred Hutchinson Cancer Center
Stage I Breast Cancer, Stage II Breast Cancer
Acupuncture Pilot Study for Cancer-related Cognitive Function
This study is being done to explore whether acupuncture can improve cognitive difficulties in patients diagnosed with cancer.
- Conditions
- Stage I Breast Cancer, Stage II Breast Cancer, Stage III Breast Cancer, Stage I Colorectal Cancer
- Trial name
- NCT04007770
- Testing
- Acupuncture, 16 week waiting period + optional Acupuncture
- Where
- 6 sites in United States
- Volunteers
- 48 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Actinic Keratosis
ACT01 in Combination With Comp01-04 in Patients With Actinic Keratosis
The purpose of this study is to determine whether or not ACT01 is effective and tolerable alone or when used in combination with Comp01, Comp02, Comp03 or Comp04 in patients with facial and/or scalp keratosis.
- Trial name
- NCT02126670
- Testing
- ACT01, Comp01, Comp02
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- Promius Pharma, LLC
Peripheral Neuropathy
L-glutamine Supplementation to Alleviate Symptoms of Taxane-Induced Neuropathy in Patients With Breast Cancer
The purpose of the study is to determine whether daily, high-dose administration of l-glutamine can reduce numbness and tingling caused by a taxane chemotherapy in patients with breast cancer.
- Trial name
- NCT02215083
- Testing
- L-glutamine
- Where
- United States
- Sponsor
- Eastern Regional Medical Center
Breast Cancer
A Study of Avastin (Bevacizumab) and Sequential Chemotherapy in Patients With Primary HER2 Negative Operable Breast Cancer.
This single arm study will assess the efficacy and safety of a combination of Avastin and docetaxel following cyclophosphamide and doxorubicin, in patients with HER2 negative operable breast cancer.
- Trial name
- NCT00559754
- Testing
- bevacizumab [Avastin], Docetaxel, Standard chemotherapy
- Where
- 6 sites in Spain
- Volunteers
- 72 people
- Sponsor
- Hoffmann-La Roche
Melanoma Stage III or IV
Dendritic Cell Vaccination in Melanoma Patients Scheduled for Regional Lymph Node Dissection
Dendritic cells (DCs) are the professional antigen-presenting cells of the immune system. As such they are currently used in clinical vaccination protocols in cancer patients, and both immunological and clinical responses have…
- Trial name
- NCT00243594
- Testing
- Peptide-pulsed dendritic cells
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- Radboud University Medical Center
Diffuse Cutaneous Systemic Sclerosis
A Study With TEPEZZA in Patients With Diffuse Cutaneous Systemic Sclerosis (dcSSc)
The overall objective is to investigate the safety, tolerability and effect on insulin-like growth factor-1 (IGF-1), inflammatory and fibrotic biomarkers of TEPEZZA (teprotumumab-trbw, HZN-001), a fully human monoclonal antibody…
- Trial name
- NCT04478994
- Testing
- TEPEZZA
- Where
- 7 sites in United States
- Volunteers
- 3 people
- Sponsor
- Amgen
Stage II Breast Cancer, Stage IIA Breast Cancer
Aerobic and Strength Training Exercise in Improving Fitness and Arm Health During and After Radiation Therapy in Patients With Stage II-III Breast Cancer
This randomized pilot phase I/II trial studies how well aerobic and strength training exercise works in improving fitness and arm health during and after radiation therapy consisting of regional nodal radiation in patients with…
- Conditions
- Stage II Breast Cancer, Stage IIA Breast Cancer, Stage IIB Breast Cancer, Stage III Breast Cancer
- Trial name
- NCT03102866
- Testing
- Best Practice, Exercise Intervention, Quality-of-Life Assessment
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Breast Cancer
Evaluation and Modeling of the G-CSF Effect on the Evolution of Neutrophils During Chemotherapy Based on Eribulin
The anti-cancer cytotoxic chemotherapy is often the cause of neutropenia of grade IV or febrile neutropenia. Those neutropenia, in addition to being a comorbidity factor, result in dose reductions and/or temporary or permanent…
- Trial name
- EMEG-E-01 (NCT02841722)
- Testing
- ERIBULIN + G-CSF (Granulocyte-Colony Stimulating Factor)
- Where
- France
- Volunteers
- 95 people
- Sponsor
- Centre Georges Francois Leclerc
Immunotherapy
Treatment of Metastatic Melanoma With Autologous Melan-A/MART-1 Specific CTL Clones
Most of HLA-A2 melanomas express Melan-A/MART-1 antigen and are recognized by tumor reactive Melan-A specific T lymphocytes. By using blood samples from HLA-A2 melanoma patients (stage III and IV), our goal is to produce a tumor…
- Trial name
- NCT00720031
- Testing
- autologous Melan-A/MART-1 specific CTL clones
- Where
- France
- Volunteers
- 16 people
- Sponsor
- Nantes University Hospital
Cutaneous Lupus Erythematosus
Study of Edecesertib in Participants With Cutaneous Lupus Erythematosus (CLE)
The primary objective of this study is to evaluate the safety and tolerability of edecesertib (formerly GS-5718) in participants with cutaneous lupus erythematosus (CLE) with or without systemic lupus erythematosus (SLE).
- Trial name
- LYNX (NCT04809623)
- Testing
- Edecesertib, Standard of Care
- Where
- 5 sites in United States
- Volunteers
- 3 people
- Sponsor
- Gilead Sciences
Breast Cancer
Tamoxifen, Ovarian Ablation, and/or Combination Chemotherapy in Treating Premenopausal Women With Stage I, Stage II, or Stage IIIA Invasive Breast Cancer
RATIONALE: Estrogen can stimulate the growth of breast cancer cells. Hormone therapy using tamoxifen may fight breast cancer by blocking the uptake of estrogen.
- Trial name
- NCT00002580
- Testing
- cyclophosphamide, fluorouracil, goserelin acetate
- Where
- 10 sites in United Kingdom
- Volunteers
- 1,000 people
- Sponsor
- Scottish Cancer Therapy Network
Breast Carcinoma, Endometrial Carcinoma
Caloric Restriction Before Surgery in Treating Patients With Endometrial, Prostate, or Breast Cancer
The purpose of this trial is to determine that sort term calorie restriction will affect tumor biology in biopsy proven breast, endometrial or prostate cancers, which will positively impact biomarkers including miR-21, an…
- Conditions
- Breast Carcinoma, Endometrial Carcinoma, Prostate Carcinosarcoma
- Trial name
- NCT02983279
- Testing
- Dietary Intervention, Counseling, Therapeutic
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Hair Loss/Baldness
Role of Bandage After FUE Hair Transplantation
The aim of this interventional study is to determine the role of bandage on the follicular donor sites on the scalp after FUE hair transplantation.
- Trial name
- NCT05984862
- Testing
- Bandage
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Pak Medical and Diagnostic Center
Melanoma (Skin)
Patient-led Surveillance Compared to Clinician-led Surveillance in People Treated for Localised Melanoma.
The purpose of this pilot study is to evaluate digitally supported skin self-examination compared to usual care in people treated for localised melanoma.
- Trial name
- MEL-SELF (NCT03581188)
- Testing
- Patient-led surveillance, Clinician-led surveillance
- Where
- 3 sites in Australia
- Volunteers
- 100 people
- Sponsor
- University of Sydney
Breast Cancer, Heart Failure
Multidisciplinary Approach to Novel Therapies in Cardiology Oncology Research
While trastuzumab has been shown to prevent recurrences of breast cancer, some women may also experience damage to their heart muscle (including heart failure) as a result of their treatment.
- Trial name
- MANTICORE (NCT01016886)
- Where
- Canada
- Volunteers
- 99 people
- Sponsor
- University of Alberta
Metastatic Uveal Melanoma, Metastatic Cutaneous Melanoma
Hepatic Arterial Infusion of Autologous Tumor Infiltrating Lymphocytes in Patients With Melanoma and Liver Metastases
The purpose of this study is to evaluate the feasibility, safety and tolerability of treatment with autologous tumor infiltrating lymphocytes (TIL) administered via hepatic arterial infusion in patients with liver metastases…
- Trial name
- HAITILS (NCT04812470)
- Testing
- Autologous Tumor Infiltrating Lymphocytes, Melphalan, Interleukin-2
- Where
- Sweden
- Volunteers
- 8 people
- Sponsor
- Vastra Gotaland Region
Breast Neoplasms
Evaluation of Cryoprotection Induced Nail Toxicity Docetaxel Low Cumulative Dose
For the specific patient population studied receiving 5-Fluorouracil, epirubicin and cyclophosphamide - Docetaxel sequence (cumulative dose <300 mg / m2), using a cryoprotection has never been assessed.
- Trial name
- BANQUISE (NCT02283983)
- Testing
- mittens and booties, cooling helmet
- Where
- 10 sites in France
- Volunteers
- 319 people
- Sponsor
- Centre Hospitalier Departemental Vendee
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.