Clinical trials: Descemet's Membrane Disorder
Fuchs' Endothelial Dystrophy
Evaluation of the Efficacy of Descemet Membrane Transplantation for the Treatment of Fuchs' Endothelial Dystrophy
Fuchs Endothelial Dystrophy (FED) is a degenerative disease affecting the corneal endothelium. The current gold-standard for treatment of severe FED is endothelial keratoplasty, wherein a cadaveric Descemet's membrane /…
- Trial name
- NCT03275896
- Testing
- Descemet Membrane Transplantation
- Where
- Singapore
- Volunteers
- 20 people
- Sponsor
- Singapore National Eye Centre
Fuchs' Endothelial Dystrophy, Pseudophakic Bullous Keratopathy
The Effect Of Preoperative Parameters On Success After DMEK Surgery
The aim of this study is to evaluate the effect of preoperative parameters on surgical results in Descemet Membrane Endothelial Keratoplasty (DMEK) surgery.
- Conditions
- Fuchs' Endothelial Dystrophy, Pseudophakic Bullous Keratopathy, Descemet's Membrane; Defect, Herpetic Keratitis
- Trial name
- NCT04420429
- Testing
- Descemet membrane endothelial keratoplasty (DMEK)
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Beyoglu Eye Research and Education Hospital
Angle Glaucoma Open
Incidence of Descemet Membrane Detachment Post GATT by AS OCT
detection of Incidence of Descemet membrane detachment post gonioscopy-assisted transluminal trabeculotomy by anterior segment optical coherence tomography in patients with open angle glaucoma.
- Trial name
- NCT05932940
- Testing
- Gonioscopy-Assisted Transluminal Trabeculotomy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Endothelial Corneal Dystrophy
Predictive Factors of Good Results After Primary Descemet's Membrane Endothelial Keratoplasty (DMEK)
Aim: Identify predictive factors of good results after primary Descemet's Membrane Endothelial Keratoplasty (DMEK) in Fuchs Endothelial Corneal Dystrophy (FECD).
- Trial name
- GOODRMEK (NCT04469933)
- Volunteers
- 102 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Fuchs' Endothelial Dystrophy
Eye Drops for Early Morning-Associated Corneal Swelling of the Cornea
This study evaluates the efficacy of hyperosmolar eye drops on early morning edema of the cornea in patients with Fuchs' endothelial corneal dystrophy (FECD).
- Trial name
- EDEMAS (NCT04140422)
- Testing
- Hyperosmolar eye drops
- Where
- Germany
- Volunteers
- 68 people
- Sponsor
- University Eye Hospital, Freiburg
Fuchs' Endothelial Corneal Dystrophy, Bullous Keratopathy
Outcome After Descemet Membrane Endothelial Keratoplasty (DMEK) and Ultra-thin Descemet Stripping Automated Endothelial Keratoplasty (DSAEK)
The purpose of this study is evaluate the outcome after posterior lamellar keratoplasty (DMEK and Ultra-thin DSAEK) for corneal transplantation.
- Conditions
- Fuchs' Endothelial Corneal Dystrophy, Bullous Keratopathy, Iridocorneal Endothelial Syndrome, Posterior Polymorphous Dystrophy
- Trial name
- NCT02020044
- Testing
- Endothelial Keratoplasty
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Charite University, Berlin, Germany
Cystoid Macular Edema, Fuchs Dystrophy
Descemet Membrane Endothelial Keratoplasty vs. Descemet's Stripping With Endothelial Keratoplasty vs. Descemet Stripping Only
This study aims to evaluate and compare incidence of post-operative cystoid macular edema (CME) after Descemet Membrane Endothelial Keratoplasty (DMEK), Descemet's Stripping Automated endothelial Keratoplasty (DSEK) and Descemet…
- Trial name
- NCT04527523
- Testing
- Optical Coherence Tomography
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Wake Forest University Health Sciences
Fuchs' Endothelial Dystrophy
Trial of Netarsudil for Acceleration of Corneal Endothelial Restoration
Subjects with Fuchs dystrophy will be randomized to use either netarsudil or placebo eye drops to determine if the use of netarsudil accelerates migration of host peripheral corneal endothelial cells to restore the central…
- Trial name
- NCT03971357
- Testing
- Netarsudil
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Price Vision Group