Clinical trials: Desflurane
Anesthesia
The Quality of Recovery After General Anesthesia With Desflurane and Sevoflurane in Endoscopic Ureteral Lithotripsy
The good quality of recovery after general anesthesia is one of goals for short procedures and ambulatory surgeries. The study's objective was to compare the quality of recovery after general anesthesia with desflurane and…
- Trial name
- NCT04712162
- Testing
- Other
- Where
- Vietnam
- Volunteers
- 60 people
- Sponsor
- Gia Dinh People Hospital
Intensive Care Unit Syndrome
Different Volatile Anaesthetics and the Depth of Long Term ICU Sedation
The MIRUS system (TIM, Andernach, Germany) as well as the AnaConDa uses a reflector to conserve volatile anaesthetics (VA). Both systems can be paired with ICU ventilators, but MIRUS features an automated control of end-tidal VA…
- Trial name
- NCT03860129
- Testing
- Isoflurane, Sevoflurane, Desflurane
- Volunteers
- 30 people
- Sponsor
- Ruhr University of Bochum
Postoperative Cognitive Dysfunction
LINC01844 as a Diagnostic Biomarker for POCD in Elderly Patients
Postoperative cognitive dysfunction (POCD) is a common complication after surgery that is associated with more adverse events and death.
- Trial name
- NCT06387836
- Testing
- Isoflurane 0.8 MAC, Desflurane 0.8MAC
- Where
- China
- Volunteers
- 85 people
- Sponsor
- Shanghai Zhongshan Hospital
Colorectal Neoplasms
DEXDES Trial: Dexmedetomidine-Desflurane Combination in Laparoscopic Colectomy
This randomized double-blind controlled clinical trial aims to evaluate the efficacy and safety of combining Dexmedetomidine with Desflurane in patients undergoing elective laparoscopic colectomy.
- Trial name
- NCT07239479
- Testing
- Dexmedetomidine + Desflurane, Desflurane + Normal Saline
- Where
- Vietnam
- Volunteers
- 40 people
- Sponsor
- Tam Anh Research Institute
Postoperative Cognitive Dysfunction, Postoperative Delirium
The Effect of Desflurane on Postopertative Cognitive Dysfunction
The purpose of this study is to determine the effect of desflurane on postoperative cognitive dysfunction
- Trial name
- NCT04541823
- Testing
- Desflurane, Propofol
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Beijing Chao Yang Hospital
Endoscopic Sinus Surgery
PRD-guided Analgesia During FESS for Intraoperative Blood Loss
The aim of this randomized trial is to assess the utility of Pupillary Dilatation Reflex (PRD) for monitoring pain perception intraoperatively and its influence on intraoperative blood loss, quality of surgical field using…
- Trial name
- FESSPRD (NCT03417206)
- Testing
- Remifentanil, pupillary dilatation reflex
- Volunteers
- 120 people
- Sponsor
- Medical University of Silesia
General Anesthesia
Comparison of Desflurane and Propofol on Quality of Recovery in Patients Undergoing Robotic or Laparoscopic Gastrectomy
The purpose of this study is to investigate whether propofol can improve quality of recovery compared to desflurane in patients undergoing robotic or laparoscopic gastrectomy.
- Trial name
- NCT02515968
- Testing
- Desflurane, Propofol
- Sponsor
- Yonsei University
Ear Deformities, Acquired
The Effect of General Anesthesia on the Middle Ear Pressure
The investigators aimed to examine the effect of sevoflurane and desflurane, agents used in patients who do not have any ear pathology and undergo surgery under general anesthesia, on the MEP.
- Trial name
- NCT03100604
- Testing
- desflurane,, Sevoflurane
- Volunteers
- 50 people
- Sponsor
- Trakya University
Cerebral Ischemia
Desflurane Versus Propofol in the Sitting Position
The investigators hypothesized that both propofol and desflurane would decrease the regional oxygen saturation (rSO2) but propofol is likely to reduce rSO2 more than sevoflurane when patients are raised to the sitting position.
- Trial name
- NCT01436799
- Testing
- propofol, Desflurane, alfentanil
- Volunteers
- 40 people
- Sponsor
- Gachon University Gil Medical Center
Laparoscopic Cholecystectomy, Postoperative Sore Throat
Low-Flow Sevoflurane and Desflurane Anesthesia in Laparoscopic Cholecystectomy
Several studies have demonstrated that inhalational anesthetic agents such as desflurane and sevoflurane may cause varying degrees of postoperative sore throat, hoarseness, and cough in orotracheally intubated patients.
- Trial name
- NCT07440758
- Testing
- Sevoflurane, Desflurane
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Kayseri City Hospital
Lung Volume Reduction Surgery
Effects of Desflurane and Propofol During Lung Volume Reduction Surgery
Patients presenting for lung volume reduction are very high risk patients and it is important they receive the best anesthetic available. This study aims to answer which is the best anesthetic for managing such cases.
- Trial name
- NCT04226625
- Testing
- Propofol, Desflurane
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Columbia University
Postoperative Cognitive Function
Comparison of Neuroprotection by Propofol and Desflurane for POCD Following Subarachnoid Hemorrhage Surgery
Aneurysmal subarachnoid hemorrhage (aSAH) is characterized by the rupture of an intracranial aneurysm and accumulation of blood in the subarachnoid space with 30 to 40% mortality rate.
- Trial name
- NCT02987218
- Testing
- Propofol, Desflurane
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Catheter Site Discomfort, Complications
Sevoflurane Versus Desflurane for Catheter-related Bladder Discomfort
We want to evaluate the efficacy of the sevoflurane and desflurane for the prevention of catheter-related bladder discomfort.
- Conditions
- Catheter Site Discomfort, Complications, Anesthesia, Urinary Bladder Neoplasms
- Trial name
- NCT02096224
- Testing
- Sevoflurane, Desflurane
- Where
- South Korea
- Volunteers
- 108 people
- Sponsor
- Seoul National University Hospital
Hip Arthroplasty
Influence of Sevoflurane and Desflurane on Postoperative Sore Throat
This investigation is planned to compare the incidence and severity of postoperative sore throat according to the use of sevoflurane or desflurane.
- Trial name
- NCT03259672
- Testing
- Sevoflurane, Desflurane
- Volunteers
- 100 people
- Sponsor
- Keimyung University Dongsan Medical Center
Healthy, End Stage Renal Disease
Comparison of the Protective Effect of Desflurane and Propofol in Patients With Renal Transplantation
Ischemia/reperfusion (IR) injury is the major cause of early renal dysfunction and acute renal failure of the transplanted kidney after renal transplantation. In 1986, Murry et al.
- Trial name
- NCT01132157
- Testing
- Desflurane, Propofol
- Where
- South Korea
- Volunteers
- 99 people
- Sponsor
- Yonsei University
Visual Evoked Potentials
Effects of Desflurane-propofol Balanced Anesthesia on Visual Evoked Potentials Monitoring
Intraoperative flash visual evoked potentials (FVEPs) can be used to monitor the integrity of the visual pathway in real-time during surgeries, and is to prevent the damage and deterioration of visual function caused by visual…
- Trial name
- NCT05465330
- Testing
- Desflurane, Desflurane, Propofol
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Beijing Tiantan Hospital
Perioperative Respiratory Mechanics
Effect of Sevoflurane vs Desflurane on Mechanical Power in Laparoscopic Cholecystectomy
This single-center, prospective, randomized, assessor-blinded clinical trial aims to compare the effects of sevoflurane and desflurane anesthesia on intraoperative mechanical power in adult patients undergoing elective…
- Trial name
- VAPOR (NCT07295158)
- Testing
- Sevoflurane, Desflurane
- Where
- Turkey (Türkiye)
- Volunteers
- 138 people
- Sponsor
- Konya City Hospital
Airway Complications
Optimal End-Tidal (ET) Sevoflurane and Desflurane Concentration for Extubation of Supreme Laryngeal Mask Airway (LMA) in Adults
The purpose of this study is to determine the optimal volatile anaesthetic (sevoflurane and desflurane) to remove a Supreme LMA in adults in which there is minimal airway response.
- Trial name
- NCT01083953
- Testing
- Sevoflurane, Desflurane
- Where
- Malaysia
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Postoperative Pain, General Anesthesia
ANI-Guided Anesthetic Desflurane Consumption
General anesthesia requires precise titration of inhaled anesthetics like desflurane and opioids like remifentanil to balance sedation, analgesia, and hemodynamic stability.
- Conditions
- Postoperative Pain, General Anesthesia, Laparoscopic Cholecystectomy
- Trial name
- NCT06982209
- Testing
- Analgesia/Nociception Index (ANI)
- Where
- South Korea
- Volunteers
- 125 people
- Sponsor
- Wonkwang University Hospital
Obesity, Bariatric Surgery
Swap Anesthetic Versus Continuous Desflurane in Adults Undergoing Bariatric Surgery
This randomized, parallel-group, non-inferiority clinical trial aims to evaluate whether an anesthetic swap strategy consisting of sevoflurane followed by desflurane 30 minutes before the end of surgery is non-inferior to…
- Trial name
- SWAP (NCT07748247)
- Testing
- Desflurane, Sevoflurane-Desflurane
- Where
- Chile
- Volunteers
- 82 people
- Sponsor
- Clínica Dávila