Clinical trials: Detection
Cervical Cancer
Lab-on-a-chip Detection of Cervical Cancer Tumour Markers
This study aims to establish whether tumour markers measured from cytological samples can improve cervical cancer detection both prior to treatment and after treatment during follow up.
- Trial name
- MODULAR (NCT03380741)
- Testing
- Tumour markers detection
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Royal Marsden NHS Foundation Trust
Skin Lesion
Smartphone Application to Detect Skin Lesions
The primary objective of Part One of this study is to determine the sensitivity of an automated total body digital photography (TBDP) app to detect color and size changes in the human skin, and whether a new lesion has arisen.
- Trial name
- NCT02740257
- Testing
- Photos
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Dental Caries, Teeth Loss
Impact of the Radiographic Examination on Diagnosis and Treatment Decision of Caries Lesions in Primary Teeth
Radiographs have been used to aid dentists in detecting the presence of cavities in the deciduous teeth of children. This procedure is globally recommended because the conventional clinical examination usually overlooks some…
- Conditions
- Dental Caries, Teeth Loss, Quality of Life
- Trial name
- CARDEC-1 (NCT02078453)
- Testing
- Dental treatment
- Where
- Brazil
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Breast Cancer
Clinical Investigation to Evaluate the Ability of MammoWave in Breast Lesions Detection
This is a multicentric, single arm, prospective, stratified by breast density clinical investigation using Mammowave that is a device, which uses microwaves instead of ionizing radiation (X-ray)for breast lesions(BL) detection.
- Trial name
- DE-17-17 (NCT04253366)
- Testing
- Clinical investigation device class IIa not marked CE
- Where
- 3 sites in Italy, Spain
- Volunteers
- 353 people, healthy volunteers welcome
- Sponsor
- Umbria Bioengineering Technologies
Caries
Reliability of Fluorescent Camera in Diagnosis of Occlusal Carious Lesion
This study will be conducted to compare the diagnostic predictive values of a light induced fluorescence camera and Caries detection dye versus visual assessment method in identification of occlusal carious lesion.
- Trial name
- NCT03224962
- Testing
- fluorescence camera
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Cairo University
Predictive Value of Tests, Vital Signs
Remote Patient Monitoring and Detection of Possible Diseases With Artificial Intelligence Telemedicine System
Remote patient monitoring and detection of possible diseases with Artificial Intelligence Telemedicine System
- Conditions
- Predictive Value of Tests, Vital Signs, Laboratory Critical Values, Relative Value Scales
- Trial name
- AI - diseases (NCT05241483)
- Testing
- mesure valition
- Where
- Turkey (Türkiye)
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Setint AI Robotic Sistem Egitim ve Danısmanlık San. Tic. A.S.
Pregnancy
Testing a Wearable Monitor for Fetal Heart Rate Estimation, Fetal Movement and Uterine Activity Detection
Owlet Baby Care, Inc. has developed a wearable fabric band pregnancy monitor, to be worn around the maternal abdomen incorporating electrocardiogram sensors.
- Trial name
- NCT04450251
- Testing
- Data Collection
- Where
- United States
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Owlet Baby Care, Inc.
Streptococcal Infections
Rapid Detection of Group B Streptococcus (Strep)-Labor and Delivery Study
The purpose of this study is to determine whether a rapid bedside diagnosis of group B strep (GBS) growing in the vagina and rectum can be performed with similar success to the routine culture in women who are in labor.
- Trial name
- NCT00330642
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Michigan
Pregnancy Complications
Early PrEgnancy Complications Testing
The aim of this study is the early (presymptomatic) detection of pregnancy complications, which could contribute to a preventive treatment.
- Trial name
- ExPECT (NCT04079361)
- Testing
- Blood samples
- Where
- Belgium
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Atherosclerosis, Subclinical Atherosclerosis
DETECTion of the Prevalence of Silent Atherosclerosis Across Adult Life - Phase I of REACT
Atherosclerosis is preventable, yet it continues to significantly contribute to global morbidity and mortality. Atherosclerosis may occur early in life and may present in all vascular territories.
- Conditions
- Atherosclerosis, Subclinical Atherosclerosis, Cardiovascular Diseases
- Trial name
- DETECT (NCT06692127)
- Where
- 5 sites in Denmark, Spain
- Volunteers
- 16,808 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Diabetes Mellitus, Medical Device
Clinical Validation of mμSORS for Noninvasive Blood Glucose Detection
This is a single-center, open-label, prospective study. Blood glucose was measured at different time points during oral glucose tolerance testing in healthy subjects and patients with type 2 diabetes mellitus, using both venous…
- Trial name
- NCT05504005
- Testing
- Multi-channel Microspatial Offset Raman Scattering Spectroscopy (mμSORS) for Noninvasive Blood Glucose Detection
- Where
- China
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Left Ventricular Dysfunction, Ventricular Dysfunction
Low Ejection Fraction in Single Lead ECG- Ochsner
The purpose of this research is to prospectively test and validate the single-lead Low EF algorithm in outpatients in order to test the performance of a single-lead ECG based algorithm to identify people with decreased left…
- Conditions
- Left Ventricular Dysfunction, Ventricular Dysfunction, Heart Diseases, Cardiovascular Diseases
- Trial name
- NCT05010642
- Testing
- Use of Eko DUO electronic Stethoscope
- Where
- United States
- Volunteers
- 307 people, healthy volunteers welcome
- Sponsor
- Eko Devices, Inc.
COVID-19
COVID-19 Infection Control Using H2O2 Mouth Wash and Nasal Spray
Hydrogen peroxide is produced physiologically by oral bacteria and plays a significant role in the balance of oral microecology since it is an important antimicrobial agent.
- Trial name
- NCT04878042
- Testing
- Hydrogen peroxide
- Where
- Italy
- Volunteers
- healthy volunteers welcome
- Sponsor
- EPISTATA
Intervention
Protocol: Feasibility of an Online Intervention to Increase Awareness of Gynaecological Cancer in UK Students
In the UK more than 2500 young people are diagnosed with cancer each year, including gynaecological cancers) and almost a third will be diagnosed within accident and emergency departments.
- Trial name
- GoCheck (NCT07147283)
- Testing
- Educational film and volitional help sheet
- Where
- United Kingdom
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Leeds Beckett University
Early Detection of Cancer, Cancer
PATHFINDER 2: A Multi-Cancer Early Detection Study
This is a prospective, multi-center interventional study of the GRAIL multi-cancer early detection (MCED) test with return of test results for participants enrolled through healthcare systems in North America.
- Trial name
- NCT05155605
- Testing
- Multi-Cancer Early Detection Test
- Where
- 56 sites in United States, Canada
- Volunteers
- 35,883 people, healthy volunteers welcome
- Sponsor
- GRAIL, Inc.
Cancer, Multi Cancer Early Screening
The Jinling Cohort
The Jinling Cohort is a prospective, multicenter cohort study in which 15,000 eligible individuals aged 45-75 in Nanjing China will be enrolled.
- Conditions
- Cancer, Multi Cancer Early Screening, Liquid Biopsy
- Trial name
- NCT06011694
- Testing
- MERCURY test, health questionnaires and annual routine physical exams
- Where
- 2 sites in China
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Nanjing Shihejiyin Technology, Inc.
Lung Cancer, Metastatic Cancer in the Lungs
Early Detection of Lung Cancer Via Bi-plane Correlation Chest Imaging
This project proposes a new method, Bi-plane Correlation Imaging (BCI), for improved detection of subtle lung nodules. In BCI, two digital radiographs of the chest are acquired within a short time interval from slightly different…
- Trial name
- NCT00673283
- Testing
- bi-plane chest radiography
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Duke University
Cough
Accuracy of Cough Detection in Healthy Adults
Cough is part of the defense mechanism to protect the lung from foreign particles and remove secretions from the airways. However, at times it becomes a bothersome, annoying symptom that interferes with the quality of life, sleep…
- Trial name
- NCT00907491
- Testing
- pulmonary sounds analyzer
- Where
- Israel
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- KarmelSonix Ltd.
Autism Spectrum Disorder
Early, Objective Detection of Autism.
1- To test the hypothesis that using the SensoDetect Brainstem Evoked Response Audiometry (BERA) technology may be an effective support tool for pediatricians to detect autism.
- Trial name
- NCT06447285
- Testing
- SensoDetect BERA technology
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- SensoDetect
Colon Polyps and Adenomas, Colon Cancer
Polyp Detection With The Peerscope System™
The PeerScope System consists of Peer Medical camera heads, endoscopes, video system, light source and other ancillary equipment.
- Trial name
- NCT01549535
- Testing
- Colonoscopy done with:PeerMedical System and Olympus/Pentax/Fuji colonoscopy system
- Where
- 6 sites in United States, Israel and 1 more
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- PeerMedical Ltd.
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