Clinical trials: Detection
Lung Cancer
Validation of Multiparametric Models and Circulating and Imaging Biomarkers to Improve Lung Cancer EARLY Detection.
CLEARLY will focus on validation of a multifactorial "bio-radiomic" protocol for early diagnosis of lung cancer that combines circulating biomarkers and radiomic analysis.
- Trial name
- CLEARLY (NCT04323579)
- Where
- Italy
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Istituto Clinico Humanitas
Anemia (Diagnosis), Anemia
Multicenter, Prospective Study Evaluating the Accuracy of an AI-based Smartphone Application for Non-invasive Anemia Detection
Title: Multicenter, prospective study evaluating the accuracy of an AI-based smartphone application for non-invasive anemia - AnemiAI trial Short Introduction: Anemia is a common clinical condition, often underdiagnosed, with…
- Trial name
- AnemiAI (NCT07678762)
- Testing
- AnemIA App
- Where
- Brazil
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Fabio Biscegli Jatene
Diabetic Foot, Type 2 Diabetes Mellitus With Established Diabetic Nephropathy
The Effectiveness of Improving Self-care After Counseling for the Diabetics Mellitus Foots Around Chiayi Region
Objectives: Preventing diabetic foot problems (DFP) and associated consequences, such as amputation, is a critical in rural regions.
- Trial name
- NCT01299246
- Testing
- Michigan Neuropathy Screening Instrument
- Where
- Taiwan
- Volunteers
- 386 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Radiography, Emergencies
PARamedical Abnormalties Detection of Traumatic Bone Lesion of the extremitIeS
This study assesses the performance of radiographers in detecting radiological anomalies of the appendicular skeleton in emergency department.
- Conditions
- Radiography, Emergencies, Diagnostic
- Trial name
- PARADIS_1 (NCT05076188)
- Testing
- Emergency radiography
- Where
- France
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Adverse Drug Events
Enhancing the Detection and Management of Adverse Drug Events in Nursing Homes
Adverse drug events (ADEs) are the most clinically significant and costly medication-related problems in nursing homes (NH) and are associated with an estimated 93,000 deaths a year and as much as $4 billion of excess healthcare…
- Trial name
- NCT01531088
- Testing
- Active medication monitoring
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Breast Cancer Female, Breast Cancer
Oncoliq: Early Breast Cancer Detection Based on Liquid Biopsies and microRNAs
Oncoliq is a novel early breast cancer detection test based on liquid biopsies and microRNAs. This innovative test aims to improve the accuracy of cancer detection, thereby reducing patient mortality and healthcare costs.
- Conditions
- Breast Cancer Female, Breast Cancer, Breast Carcinoma
- Trial name
- NCT06439940
- Testing
- Blood sample extraction
- Where
- Argentina
- Volunteers
- 364 people, healthy volunteers welcome
- Sponsor
- Oncoliq US Inc
Healthy
Tramadol to Improve Its Detection in Biological Matrices in Anti-doping Controls
Orally single dose administration of Tramadol 75 mg for ultra-rapid metabolizers and 100 mg for extensive and poor metabolizers will be administered with the objective to evaluate urine and blood concentrations in healthy…
- Trial name
- NCT05925686
- Testing
- Tramadol.
- Where
- Spain
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Parc de Salut Mar
Gastrointestinal Hemorrhage, Volatile Organic Compounds
Volatile Organic Compounds (VOCs) of Exhaled Breath in Patients With GI Bleeding
Cross sectional case-control study investigating the difference of volatile organic compound in the exhaled breath of the patients with GI bleeding and normal population.
- Trial name
- NCT04226079
- Testing
- Collection of exhaled breath
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
FRENCH STUDY
Narrow-Band Imaging (NBI) Versus Lugol Chromoendoscopy in the Detection of Oesophagus Squamous Cell Carcinoma in High Risk Population
Narrow-Band Imaging (NBI) is as sensitive as Lugol chromoendoscopy to detect oesophageal squamous cell carcinoma (SCC) and appears more specific than Lugol chromoendoscopy in expert centres but its specificity in current practice…
- Trial name
- NCT04224896
- Testing
- UPPER ENDOSCOPY
- Volunteers
- 335 people, healthy volunteers welcome
- Sponsor
- Hôpital Edouard Herriot
Tetanus
TETANUS Antibody Detection in Saliva Study
This study aims to design, develop and optimise a non-invasive, saliva sample-based point-of-care lateral flow test for use in low and middle income settings that can return a qualitative result on whether an individual has or…
- Trial name
- TETANUS (NCT07446166)
- Testing
- Point of care, saliva-based lateral flow test, Blood based immunoassay
- Where
- Rwanda
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Gastric Cancer
Gastric In Vivo Study
The overall objective of this pilot study is to determine whether multispectral imaging increases the diagnostic accuracy of the current standard of high-definition white-light endoscopy for the detection of gastric neoplasia…
- Trial name
- NCT02207959
- Testing
- Proflavine Hemisulphate salt, White-light examination, Imaging with High Resolution Microendoscope
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Susana Gonzalez
Liver Cirrhoses, Hepatic Encephalopathy
Role of MRI in Detection of Minimal Hepatic Encephalopathy
Introduction Liver cirrhosis (LC) is irreversible fibrosis of the liver (1) and it remains a public health problem. One of the complications of the cirrhosis is hepatic encephalopathy (HE) which is defined as brain dysfunction…
- Trial name
- NCT04131205
- Testing
- Magnetic Resonance Imaging
- Where
- Slovenia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Endomicroscopy, Inflammatory Bowel Syndrome
Endomicroscopy, IBS and Food Intolerance
Background: The immediate endoscopic identification and diagnosis of intraepithelial structures and immediate and delayed reactions to allergens in the mucosal surface of the gut are unmet goals in the diagnosis and management of…
- Conditions
- Endomicroscopy, Inflammatory Bowel Syndrome, Food Intolerance
- Trial name
- NCT01692613
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital Schleswig-Holstein
Stroke, Acute
Study: SONAS Ultrasound for Detecting Stroke SONAS Ultrasound for Detecting Stroke
The purpose of this research study is to test a new medical device, called SONAS. The SONAS device is a portable, battery-powered ultrasound device to detect strokes in the prehospital environment, such as emergency vehicles (eg.
- Trial name
- NCT03296852
- Testing
- SONAS Ultrasound Device, Lumason
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Psychosis
E-Detection Tool for Emerging Mental Disorders
Psychosis is a severe mental disorder that involves abnormal experiences and altered behaviour. Although the onset of psychosis occurs in young people, most cases will only be identified later in the course of illness.
- Trial name
- ENTER (NCT05127278)
- Where
- 2 sites in United Kingdom
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- King's College London
Neisseria Gonorrheae Infection
Performance, Acceptability, and Usability of a Novel Rapid Lateral Flow Test for Detecting Neisseria Gonorrhoeae in Pregnant and Symptomatic Women Attending Clinics in South Africa.
Previous studies of the Neisseria gonorrhoeae (NG) lateral flow assay (LFA) have shown promising results. In East London, South Africa, the LFA demonstrated a sensitivity of 80% in asymptomatic women.
- Trial name
- GO-SA (NCT07530406)
- Testing
- Novel Lateral Flow Assay for Neisseria gonorrhoeae
- Where
- South Africa
- Volunteers
- 1,239 people, healthy volunteers welcome
- Sponsor
- Foundation for Professional Development (Pty) Ltd
Healthy
The Effect of Blood Donation on Hematological and Iron Indices and Detection of Autologous Blood Transfusion
Blood donations is a essential and crucial in the clinic. Normal biological variation of relevant biomarkers and hormones before the donation of 450 mL whole blood as well as the expected alterations in systemic levels of plasma…
- Trial name
- NCT04514978
- Testing
- Blood donation and blood transfusion
- Where
- Denmark
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Changes in Peripheral Blood Population Numbers and Type.
Stem Cell Quantification In Peripheral Blood After Hyperbaric Oxygen Therapy Treatments
This is an observational research study whose purposes are to see the effects of repeated hyperbaric oxygen therapy treatments on the levels of stem/progenitor cells in peripheral circulating blood following five days of…
- Trial name
- NCT01740908
- Testing
- Hyperbaric Oxygen Treatment
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Restorix Research Institute, LLLP
Colonic Polyps, Colonic Neoplasms
Development of Quality Indicators and Quality Improvement Plan of Colonoscopy in Experienced Endoscopist
The purpose of this study is to determine clinical factors affecting quality indicators of colonoscopy including adenoma detection rate, and whether quality of colonoscopy could be elevated by improving related factors.
- Trial name
- NCT02385552
- Testing
- Feedback
- Where
- 2 sites in South Korea
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Infiltration, IV Infiltration
Ultrasound Detection of Peripheral IV Infiltration
The purpose of this study is to determine whether commercial ultrasound imaging systems can discern normal from infiltrated tissue near a peripheral intravenous site.
- Trial name
- NCT01800552
- Testing
- Intentional infiltration of a peripheral IV site
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- ivWatch, LLC
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