Clinical trials: Detection
Sleep Disordered Breathing (SDB), Sleep Apnea
Detection of Sleep Stages and Arousals Using Neural Network Classifiers
The objective of this clinical study is to evaluate the accuracy of the Smart Mask V1 System (herein 'Smart Mask') in measuring sleep stages-Stage N1/N2, Stage N3, Rapid Eye Movement (herein 'REM'), and WAKE-arousals, and the…
- Trial name
- SSAM (NCT07136272)
- Testing
- SSAM, Polysomnography, EnsoSleep
- Where
- 3 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Pathway Medtech, LLC.
Trauma (Including Fractures), Trauma Abdomen
5 Minute 'HOT' Trauma CT Rates Of Detection Study
Many injured patients receive urgent CT imaging to identify major injury. CT imaging of trauma patients is often time critical and the accurate detection of life-threatening findings on this CT is essential.
- Conditions
- Trauma (Including Fractures), Trauma Abdomen, Trauma Blunt, Trauma Centers
- Trial name
- NCT07314437
- Testing
- Education
- Where
- United Kingdom
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital Plymouth NHS Trust
Chronic Wounds With Different Etiologies
Swab Sample Collection for the Detection of Bacterial Proteases in Wounds Assay
The objective of this study is to collect wound exudate (fluid) swab samples from Subjects who have wounds that show clinical signs of infection, as well as from Subjects who have wounds that do not show clinical signs of…
- Trial name
- NCT01750203
- Testing
- Swabs
- Where
- United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Systagenix Wound Management
Cancer
AssesSment of Early-deteCtion basEd oN liquiD Biopsy in PANCEATIC Cancer (ASCEND-PANCREATIC)
ASCEND-PANCREATIC is a prospective, multi-omics, observational study aimed at early detecting pancreatic cancer by combined assays for biomarkers of cfDNA methylation, circulating tumor DNA (ctDNA) mutation, serum protein markers…
- Trial name
- NCT05556603
- Where
- 3 sites in China
- Volunteers
- 7,062 people, healthy volunteers welcome
- Sponsor
- Ruijin Hospital
Large for Gestational Age (LGA), Pregnancy
Repeat Late GDM Testing and Cesarean Delivery Rates
The goal of this randomized trial is determine if re-testing for gestational diabetes in the third trimester after an ultrasound measurement of estimated fetal weight (EFW) or abdominal circumference greater than 90%ile decreases…
- Trial name
- NCT07708129
- Testing
- Glucose tolerance test and continuous glucose monitor
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Shauna F. Williams, MD
Lung Cancer
Lung Cancer Detection by Measuring Monocyte Activity
Purpose: To evaluate the performance of Extracellular Monitoring of Metabolic Activity Profiles of Peripheral Blood Mononuclear Cells (PBMC) analysis method in identifying lung cancer.
- Trial name
- EDLC (NCT02090166)
- Testing
- Blood test
- Where
- Israel
- Volunteers
- 950 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center
Barrett Esophagus
Early Detection of Barrett's Esophagus Through Deep Image Retrieval
Barrett's oesophagus is a condition in which the area between the oesophagus and stomach no longer closes, allowing acidic contents of the stomach to enter the oesophagus and damage the lining.
- Trial name
- NCT04478929
- Testing
- Gastroscopy
- Where
- United Kingdom
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Leigh Taylor
ADHD
Identification of Early Biomarkers of Pre-school ADHD
ADHD affects around 5% of children and manifests itself as hyperactivity, attention difficulties and motor control and balance problems.
- Trial name
- Bio-PreTDAH (NCT07440992)
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Ankle Osteoarthritis
Improving the Detection, Classification and Treatment of Misaligned Arthritic Ankles
The Veteran population is prone to foot and ankle maladies from common injuries such as sprains, and diseases such as ankle osteoarthritis (cartilage damage).
- Trial name
- IDCT (NCT03440008)
- Testing
- Dynamic 3D bone motion capture, wedged insole
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Sepsis, Organ Damage
Detection of Sepsis Occurrence by Using Blood Fluorescence
This study adopted a case-control study method to explore a reagent-free, highly sensitive, and frequently screened blood fluorescence metabolite analyzer for sepsis, which can detect the emergence of inflammatory free radicals…
- Trial name
- NCT06689189
- Testing
- Blood fluorescence metabolite analysis
- Where
- China
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Ningbo Medical Center Lihuili Hospital
Congenital Heart Disease (CHD)
Can Smartphones Listen to Your Heart? A Performance Study on Detecting Inborn Heart Diseases in Your Heart Sounds
This observational study aims to assess the performance of the software called ausculto™. ausculto™ is a collection of computer algorithms that intend to analyse heart sounds recorded from the built-in microphone of a smartphone…
- Trial name
- AUSC-CHD (NCT07376785)
- Testing
- Computer algorithms
- Where
- 2 sites in Hong Kong
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Social Anxiety
Arousal Training for Social Anxiety Disorder
The primary objective of the study is to examine the safety, usability and preliminary efficacy of a novel arousal-based biofeedback system in alleviating social anxiety.
- Trial name
- NCT02493010
- Testing
- Arousal-based biofeedback system
- Where
- Singapore
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Duke-NUS Graduate Medical School
Atrial Fibrillation
SmartWATCHes for Detection of Atrial Fibrillation
In this trial the Preventives Heartbeats algorithm will be tested in two wearable devices for its specificity and sensitivity to distinguish between AF and SR.
- Trial name
- WATCHAF (NCT02956343)
- Testing
- Five minutes pulse wave recording
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 651 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Diabetes Mellitus Type 1, Diabetes Mellitus Type 2
MoCa Test for the Early Detection of Mild Cognitive Impairment During Annual Assessment of Young Adults With Diabetes and in a Control Group Without Diabetes
T2D and cognitive impairment are two of the most common chronic condition found in persons 60 years and older. Diabetes type 2 increases with age and studies suggest that the diabetes is one of the risk factor for cognitive…
- Conditions
- Diabetes Mellitus Type 1, Diabetes Mellitus Type 2, Mild Cognitive Impairment
- Trial name
- NCT02545062
- Testing
- MoCa test
- Where
- Israel
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Clalit Health Services
Taurine in HCC
TAURINE and HCC PATIENTS
Serum taurine level beside (AFP and AFU) are of great value in early diagnosis in HCC Egyptian patients and may have a rule in identifying end-stage liver disease (ESLD) patients candidate for LDLT.
- Trial name
- NCT04193761
- Testing
- taurine level
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Alzheimer's Disease Diagnosis
Clinical Evaluation of Blood-Based Assays for Rapid Detection of Aβ Pathology in Alzheimer's Disease
Background: Blood-based biomarkers show promise in predicting Alzheimer's disease (AD) pathology and progression; however, inconsistencies in detection standards hinder clinical application.
- Trial name
- CLEAR AD (NCT06889896)
- Testing
- After Blood samples collection, these samples are analyzed at a central laboratory under blinded conditions using multiple detection methods to measure plasma levels of Aβ40, Aβ42, t-tau, and p-tau
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Anhui Provincial Hospital
Diabetes Mellitus, Type 2, Prediabetic State
PREDICT-DM: Community Pharmacy-Based Point-of-Care Testing for Undiagnosed T2DM
The goal of this observational study is to learn whether community pharmacy-based risk assessment and point-of-care HbA1c testing can help detect undiagnosed type 2 diabetes and prediabetes among adults in Irbid Governorate…
- Conditions
- Diabetes Mellitus, Type 2, Prediabetic State, Prediabetes / Type 2 Diabetes, T2DM
- Trial name
- PREDICT-DM (NCT07795918)
- Where
- Jordan
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Gastrointestinal Hemorrhage, Volatile Organic Compounds
Volatile Organic Compounds (VOCs) of Exhaled Breath in Patients With GI Bleeding
Cross sectional case-control study investigating the difference of volatile organic compound in the exhaled breath of the patients with GI bleeding and normal population.
- Trial name
- NCT04226079
- Testing
- Collection of exhaled breath
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Intraventricular Hemorrhage of Prematurity
Research on Prevention, Early Detection, and Clinical Evaluation of Intracranial Hemorrhage in Preterm Infants
1. Establish a reference curve for the lateral ventricular diameter of premature infants and determine the intervention threshold for hydrocephalus after hemorrhage in premature infants based on the reference curve, providing a…
- Trial name
- ROPEDACEOIHIPI (NCT07157020)
- Testing
- ommaya capsule implantation technique
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Atrial Fibrillation, Chronic Kidney Diseases
Check@Home: General Population Screening for Early Detection of Atrial Fibrillation and Chronic Kidney Disease
The aim of the Check@Home consortium is to set up a roadmap and infrastructure for a program to early detect atrial fibrillation and chronic kidney disease in the general population.
- Conditions
- Atrial Fibrillation, Chronic Kidney Diseases, Diabetes Mellitus, Type 2
- Trial name
- NCT06330480
- Testing
- Intervention group
- Where
- Netherlands
- Volunteers
- 320,000 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Folkert W. Asselbergs
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