Clinical trials: Detection
HIV Infections
Qualitative and Quantitative HIV RNA Detection in Saliva Using the Oragene RNA Kit
The purpose of this study is to determine if the Oragene.RNA kit is able to detect HIV RNA in saliva.
- Trial name
- NCT01344642
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Atrial Fibrillation
WIBOFA - Validation of SCT02 With ECG-App for Detection of AF
The aim of the study is to evaluate the performance of Withings SCT02 with embedded Withings ECG-app in the automatic detection of atrial fibrillation
- Trial name
- WIBOFA (NCT06351761)
- Testing
- Investigational Device (Withings SCT02) 30 second Electrocardiogram recording, Reference Device (Schiller Cardiovit FT-1) 30 second Electrocardiogram recording
- Where
- 4 sites in United States, France
- Volunteers
- 373 people, healthy volunteers welcome
- Sponsor
- Withings
Diabetes, IPMN, Pancreatic
Biophotonic Nanoparticle-enabled Laser Blood Test for Early Detection of Pancreatic Cancer
LASERBLOOD is based on a biophotonic technology that can be used to predict the development of Pancreatic Ductal Adenocarcinoma (PDAC) in particular categories of subjects at risk (e.g.
- Conditions
- Diabetes, IPMN, Pancreatic, PDAC - Pancreatic Ductal Adenocarcinoma
- Trial name
- LASERBLOOD (NCT07659639)
- Testing
- Diagnostic procedures
- Where
- Italy
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Campus Bio-Medico
Breast Cancer Screening, Artificial Intelligence (AI)
A Trial Comparing Screening Mammography With and Without Assistance From Artificial Intelligence for Breast Cancer Detection and Recall Rates in Adult Patients
The goal of this clinical trial is to compare patient-centered outcomes when screening digital breast tomosynthesis (DBT) exams are interpreted with versus without a leading FDA-cleared artificial intelligence (AI)…
- Trial name
- NCT06934239
- Testing
- Artificial intelligence (AI) decision-support tool
- Where
- 6 sites in United States
- Volunteers
- 400,000 people, healthy volunteers welcome
- Sponsor
- Jonsson Comprehensive Cancer Center
Ovarian Cancer
Early Detection of Ovarian Cancer Using Plasma Cell-free DNA Fragmentomics (Prospective Study)
The purpose of this study is to enable non-invasive early detection of ovarian cancer in high-risk populations through the establishment of a multimodal machine learning model using plasma cell-free DNA fragmentomics.
- Trial name
- NCT05693987
- Where
- China
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Adnexal Mass, Germline BRCA1 Gene Mutation
Multifactorial Risk Assessment for Breast & Ovarian Cancer Risk Detection
The objective of this project is to validate a next-generation assay that utilizes both the protein biomarkers of our already established ovarian cancer risk assessment combined with a molecular profile in both germline and early…
- Conditions
- Adnexal Mass, Germline BRCA1 Gene Mutation, Germline BRCA2 Gene Mutation, Hereditary Breast and Ovarian Cancer
- Trial name
- OVA360 (NCT04668521)
- Testing
- OVA360
- Where
- United States
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- Aspira Women's Health
Solid Tumor
Performance Evaluation of Diagnostic Accuracy of PanTum Detect Test for Detection of Solid Tumours in Known Cancer Population and in Cancer Free Population.
Performance evaluation of diagnostic accuracy (Sensitivity and Specificity) of PanTum detect Test for detection of solid tumours in known cancer population (Sick population) and in cancer free (Healthy) population.
- Trial name
- NCT06456216
- Where
- India
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Max Healthcare Insititute Limited
Breast Cancer
Positron Emission Mammography and Standard Mammography in Women at High Risk of Breast Cancer
RATIONALE: Screening tests may help doctors find cancer cells early and plan better treatment for breast cancer. It is not yet known whether positron emission mammography is more effective than standard mammography in finding…
- Trial name
- NCT00896649
- Testing
- questionnaire administration, digital mammography, positron emission mammography
- Where
- United States
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Colon Cancer Screening, Colon Cancer Surveillance
Enchasing Polyp Detection: The Effect of Adding Polyp Detection Attachment Device to Computer Aid Detection System.
Despite the widespread use of colonoscopy, the ongoing challenge of potentially missing polyps remains. Previous studies have independently shown that both Endocuff, a colonoscope attachment device for polyp detection, and…
- Trial name
- NCT06116864
- Testing
- Endocuff and GI Genius, GI Genius
- Where
- United States
- Volunteers
- 1,766 people, healthy volunteers welcome
- Sponsor
- Marshall University
Colon Polyp, Colon Adenoma
Prospective Evalulation of Artificial Intelligence-assisted Monitoring of Effective Withdrawal Time Versus Standard Withdrawal Time on Adenoma Detected Per Colonoscopy
The goal of this observational study is to assess the correlation between the artificial intelligence (AI) derived effective withdrawal time (EWT) during colonoscopy and endoscopists' adenoma per colonoscopy (APC), polyp per…
- Conditions
- Colon Polyp, Colon Adenoma, Artificial Intelligence
- Trial name
- NCT06345105
- Testing
- Endoscreener QC
- Where
- Hong Kong
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Plasmodium Infections
Randomized Trial of Two Antimalarial Treatments for Clearing Low Density P.Falciparum Parasitaemia in Sudan
In areas of seasonal malaria transmission, treatment of carriers of malaria parasites, whose parasitaemia persists at very low levels throughout the dry season, could be a useful strategy for malaria control in areas with a short…
- Trial name
- NCT00330902
- Testing
- sulfadoxine-pyrimethamine (SP) plus artesunate (AS), primaquine (PQ) plus SP+AS
- Where
- Sudan
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Ultrasound in Ascites
Ultrasound and Ascites
The aim of this study is to evaluate the role of ultrasound in the detection, characterization, and determination of the underlying cause of ascites in patients attending Assiut University Hospital
- Trial name
- NCT07196553
- Testing
- Ultrasound
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Assiut University
Proximal Dental Caries
Evaluation of Reliability of the Near-infrared Imaging System (VistaCam iX Proxi) in Comparison With Digital Radiographic Findings and ICDAS-II in Detection of Approximal Carious Lesions.
The aim of this study is to evaluate the Clinical performance of the near-infrared imaging system VistaCam iX Proxi in comparison with digital radiographic findings and ICDAS-II in detection of approximal carious lesions.
- Trial name
- NCT03923192
- Testing
- Vistacam, Bitewing radiograph
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cairo University
Sleep, Healthy Vollunteer
Wearable Sleep EEG and Auditory Stimulation in Healthy Adults
The purpose of this single-site pilot study is to evaluate the feasibility, usability, and technical performance of a wearable sleep-monitoring system that records electroencephalography (EEG) and delivers brief, low-volume…
- Trial name
- NCT07808645
- Testing
- Wearable EEG-Based Sleep Monitoring and Closed-Loop Auditory Stimulation System
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Houston
Caries Assessment, Caries; Dentin
Evaluation of Radiation-Free Caries Detection Integrated Into Intraoral Scanners Compared With Conventional Diagnostic Methods
The goal of this study is to evaluate if an intraoral scanning device with an integrated radiation-free caries detection tool (near-infrared light) can detect early tooth decay.
- Conditions
- Caries Assessment, Caries; Dentin, Caries; Initial
- Trial name
- NCT07342595
- Testing
- intraoral scan with integrated caries detection tool
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Albert Mehl
Fetal Distress With Antenatal Problem, Fetal Growth Retardation
Validation of Sensors for Long-term Non-Invasive Fetal Monitoring
A multidisciplinary team of a doctor and engineers have developed a new sensor that will be able to detect mothers' and babies' heartbeat and babies movements in late pregnancy.
- Trial name
- NCT06952777
- Testing
- Non-adhesive capacitively-coupled sensors
- Where
- United Kingdom
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Acute Respiratory Distress Syndrome
Discovery of New Early Detection Biomarkers From Peripheral Blood of Acute Respiratory Distress Syndrome(ARDS)
Acute respiratory distress syndrome (ARDS) has a very poor prognosis and high mortality. To improve the early diagnosis of ARDS, there is an urgent need for novel biomarkers of ARDS.
- Trial name
- NCT02967471
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The Third Affiliated Hospital of Southern Medical University
Colon Adenoma
BLI, NBI or White Light Colonoscopy for Proximal Colonic Adenoma
This is a prospective randomised trial comparing the proximal adenoma detection rate and miss rate by blue laser imaging (BLI), narrow band imaging or white light colonoscopy.
- Trial name
- BNW (NCT03696992)
- Testing
- Tandem colonoscopy
- Where
- Hong Kong
- Volunteers
- 884 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Epilepsy, Status Epilepticus
Training Program to Improve EEG Competence
The goal of this clinical trial is to investigate the extent to which a practice-oriented training program for intensive care nursing staff and non-physician treatment teams can contribute to the earlier detection of epileptic…
- Conditions
- Epilepsy, Status Epilepticus, Status Epilepticus, Electrographic, Status Epilepticus, Non-Convulsive
- Trial name
- EPI-Train (NCT07689084)
- Testing
- Training Program
- Where
- Germany
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University Hospital Marburg
Atrial Fibrillation
Clinical Validation of the Withings ECG Monitor for the Detection of Atrial Fibrillation
The aim of the study is to demonstrate the performance of Withings WBS08 in the automatic identification of atrial fibrillation and sinus rhythm.
- Trial name
- QDA-UE (NCT05266235)
- Testing
- Validation of the Withings bodyscan scale WBS08
- Where
- 4 sites in Belgium, France
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Withings
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