Clinical trials: Detection
Multiple Myeloma, Complication
PASCA-MM Study. Impact of the PASCA (PArcours de Santé au Cours du CAncer) Program on Complications Associated With Multiple Myeloma and/or Its Treatments in the Context of a First Hematopoietic Stem Cell Autograft, in Adults Aged 18 to 70.
This is a prospective, multicentre, phase III, randomised, controlled intervention study. Two groups of patients with equal numbers will be studied and each patient will be allocated to one of the two groups described below by…
- Trial name
- PASCA -MM (NCT05947136)
- Testing
- Interpretation of the results from the detection visit, Explaining detection results and referrals to the patient, Early medical care through the network
- Where
- 6 sites in France
- Volunteers
- 204 people
- Sponsor
- Centre Leon Berard
Mild Cognitive Impairment, Alzheimer's Disease
Aftobetin-HCl and Fluorescence Detection Measured by Sapphire II to Determine the Number and Timing of Administrations
This is an open-label study to evaluate Aftobetin-HCl and florescence detection as measured by the Sapphire II device. Performance of Part I of the study has been completed (15 subjects received a single administration of…
- Trial name
- NCT02928211
- Testing
- Sapphire II, Aftobetin-HCl, Positron Emission Tomography
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Cognoptix, Inc.
Pulmonary Disease, Chronic Obstructive
Does Pulmonary Daoyin of China Give Additional Benefit Over Usual Therapy in Management of Stable Chronic Obstructive Pulmonary Disease?
The purpose of this study is to compare the exercise capacity and pulmonary function test parameters of Chronic Obstructive Pulmonary Disease (COPD) patients who underwent usual care with and without pulmonary daoyin therapy of…
- Trial name
- NCT01482000
- Testing
- Pulmonary daoyin therapy of China, usual care
- Volunteers
- 464 people
- Sponsor
- Henan University of Traditional Chinese Medicine
Testicular Cancer, Survivorship
Late Subclinical Cardiovascular Disease in Testicular Cancer Survivors
Late subclinical cardiovascular disease in testicular cancer survivors exposed to cisplatin-based chemotherapy and bone marrow transplant
- Conditions
- Testicular Cancer, Survivorship, ASCVD, Coronary Artery Disease
- Trial name
- NCT05611307
- Testing
- Lipid profile, Coronary artery assessment, Hormone levels for hypogonadism
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Indiana University
Thyroid Nodule, Thyroid Neoplasms
The Role of an Optical Probe in Thyroid Cancer Diagnosis: Pilot Study
This study will investigate the usefulness of an optical probe in the differentiation of thyroid cancer from normal thyroid tissue in a thyroidectomy specimen.
- Conditions
- Thyroid Nodule, Thyroid Neoplasms, Thyroid Cancer
- Trial name
- NCT01792492
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Boston Medical Center
Colon Adenoma
Second Forward View Examination of Proximal Colon on Adenoma Detection Rate
This clinical trial is being conducted to assess whether second forward view examination of proximal colon could increase adenoma detection rate of right colon.
- Trial name
- NCT03619122
- Testing
- Second Examination
- Where
- China
- Volunteers
- 392 people
- Sponsor
- Ningbo No. 1 Hospital
COVID-19
Detection of Anti-COVID-19 Antibody Levels in an Hospital Population
COVID-19 (SARS-CoV-2) infection in health professionals represent a significant criticality both for the risk of spreading the disease and for the organizational aspects that follow.
- Trial name
- NCT04387929
- Testing
- Detection of anti-COVID-19 antibody level
- Where
- Italy
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Istituto Clinico Humanitas
Adenoma Detection Rate, Colonoscopy
Comparison of the Performance Between Conventional Colonoscopy and 3D Colonoscopy in Positive Fecal Immunochemical Test Group
Background: Adenoma detection rate is one of the most quality indicator: an accumulating body of evidence has shown that detection and resection of pre-cancerous adenoma by colonoscopy could effectively prevent colorectal cancer…
- Conditions
- Adenoma Detection Rate, Colonoscopy, Three Dimensional, Fecal Immunochemical Test
- Trial name
- NCT06678477
- Testing
- 3D device
- Where
- 3 sites in Taiwan
- Volunteers
- 298 people
- Sponsor
- National Taiwan University Hospital
HIV
Evaluation of Use of Clinical Decision Support System in HIV Care in Resource Constrained Settings
The purpose of this study is to determine whether the use of a Computerized Decision Support System (CDSS) in form of alerts to clinicians enhances early detection of immunological treatment failure in HIV patients.
- Trial name
- CDSS (NCT01634802)
- Testing
- EMR Only, EMR+CDSS
- Where
- Kenya
- Volunteers
- 1,460 people
- Sponsor
- Kenya Medical Research Institute
NAFLD, Diabetes Mellitus
Improving Detection and Evidence-based Care of NAFLD in Latinx and Black Patients With Type 2 Diabetes
The primary objective of this pilot study is to assess the feasibility and acceptability of an intervention for improved detection and evidence-based care of NAFLD in Latinx and Black patients with type 2 diabetes (T2D) in Duke…
- Trial name
- NAFLD-DM (NCT05844137)
- Testing
- NAFLD Education, diet/lifestyle support, T2D medication management
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Duke University
Leishmaniasis, Visceral
Evaluation of Antibody Detection Tests for Visceral Leishmaniasis Diagnosis in Eastern Africa
According to recent estimates by the World Health Organization (WHO) on eastern Africa, not all visceral leishmaniasis (VL) cases reported are confirmed by a laboratory test, probably due to limited access to accurate diagnostic…
- Trial name
- VL-DX-EAFR (NCT03646981)
- Testing
- Leishmania Ab Rapid Test (CTK, Biotech)
- Where
- 2 sites in Ethiopia, Kenya
- Volunteers
- 704 people
- Sponsor
- Foundation for Innovative New Diagnostics, Switzerland
Atrial Fibrillation, Transient Ischemic Attack
Optimal Detection of Atrial Fibrillation in TIA
Transient ischemic attack (TIA) is a common neurologic emergency. Although the detection of atrial fibrillation (AF) has identical consequences for preventive therapy in patients with ischemic stroke and TIA, the management…
- Trial name
- ODEA-TIA (NCT04075500)
- Testing
- Subcutaneously implanted event recorder (REVEAL LINQ), 28-day non-invasive continuous ECG monitoring (patch)
- Where
- 27 sites in Germany, Spain
- Volunteers
- 516 people
- Sponsor
- Alfried Krupp Krankenhaus
SARS-CoV Infection, Covid19
COVID-19: SARS-CoV-2 Detection in Saliva, Oropharyngeal and Nasopharyngeal Specimens
The aim of this study is to compare the SARS-CoV-2 detection rate using either a Saliva, oropharyngeal swabs or nasopharyngeal swab method for specimen collection.
- Conditions
- SARS-CoV Infection, Covid19, Coronavirus
- Trial name
- NCT04715607
- Testing
- Sequence of testing.
- Where
- Denmark
- Volunteers
- 27,947 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Squamous Cell Carcinoma
Human Papillomavirus on Oral Tissue, Saliva and Serum
Human papillomavirus (HPV) is one of the most prevalent infections in the world with several millions of new cases diagnosed yearly.
- Trial name
- CDHPOTSS (NCT01043328)
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Endometrial Cancer
Sentinel Node in Endometrial Cancer
Phase II, open-label, randomized pilot study. Patients will be randomized (1:1) to receive for sentinel node screening: 1. Radiotracer (RT) via cervical administration and TUMIR 2.
- Trial name
- HYBRIDENDONOD (NCT04492995)
- Testing
- injection via TUMIR of the tracer [99mTc] Tc-albumin nanocoloid-ICG (6 mCi, 4 ml), injection via TUMIR of [99mTc] Tc-albumin nanocoloid (6mCi, 8ml).
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- Judit Pich Martínez
Mild Cognitive Impairment (MCI), Alzheimer's Dementia (AD)
Expanding Access to Cognitive Health Biomarker Testing at Home
The goal of this observational study is to learn whether at-home blood biomarker testing for Alzheimer's disease risk is feasible and acceptable in older adults with cognitive concerns.
- Conditions
- Mild Cognitive Impairment (MCI), Alzheimer's Dementia (AD), Subjective Cognitive Decline (SCD), Cognitive Aging
- Trial name
- NCT07594665
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Virginia
Breast Cancer, Breast Cyst
Pilot Clinical Study on a Low-power Electromagnetic Wave Breast Imaging Device for Cancer Screening Purposes.
The trialed investigational medical imaging device is a low-power microwave breast imaging system for cancer screening purposes. It is an active device which uses non-ionizing radiation.
- Trial name
- NCT03475992
- Testing
- Low-power microwave breast imaging system
- Where
- Ireland
- Volunteers
- 25 people
- Sponsor
- MVG Industries SAS
Atrial Fibrillation, Catheter Ablation
Prospective Physician-Initiated Observational Study of The Contact Detection System (CDS) in Patients Undergoing Radiofrequency Ablation Using the Niobe™ Remote Magnetic Navigation System
This observational study evaluates peri-procedural results of the Niobe™ Remote Magnetic Navigation (RMN) ES system using the contact detection system (CDS) in patients undergoing standard of care radiofrequency ablation of…
- Trial name
- STAR (NCT03103945)
- Testing
- CDS box connection of the Niobe™ Remote Magnetic Navigation System
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Erasmus Medical Center
Barrett Esophagus, Barretts Esophagus With Dysplasia
Assessment of a Minimally Invasive Collection Device for Molecular Analysis of Esophageal Samples
This clinical trial evaluates the use of cytosponge, a minimally invasive collection device, for the detection of Barrett's esophagus (BE) in patients undergoing endoscopy.
- Conditions
- Barrett Esophagus, Barretts Esophagus With Dysplasia, Barrett's Esophagus Without Dysplasia, Esophageal Adenocarcinoma
- Trial name
- SOS4C (NCT06071845)
- Testing
- Cytosponge Procedure, Endoscopic Assessment
- Where
- 5 sites in United States
- Volunteers
- 450 people
- Sponsor
- Mayo Clinic
Meniere Disease
Non Enhanced Labyrinth Imaging for the Detection of Endolymphatic Hydrops in Meniere's Disease "NELI Study"
This study includes 30 patients with Meniere's disease confirmed with AAO-HNS criteria. The aim of this study is to compare the new optimized 3D FLAIR sequence developed at our site with a standard 3D FLAIR sequence performed 4h…
- Trial name
- NELI (NCT04569175)
- Testing
- 3D Flair sequence
- Where
- France
- Volunteers
- 14 people
- Sponsor
- University Hospital, Bordeaux
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