Clinical trials: Detection
Tuberculosis
Evaluation of the 4th Generation QuantiFERON-TB Test (QFT-Plus) for the Detection of Tuberculosis Infection
To compare the positivity rate of the investigational assay to the currently approved QuantiFERON-TB Gold In-Tube assay.
- Trial name
- NCT02687529
- Testing
- CST001
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- QIAGEN Gaithersburg, Inc
Endovascular Procedures
Safety and Accuracy of the Saranas EBBMS for the Detection of Endovascular Procedure Related Bleeding Events
To evaluate the safety and accuracy of the Saranas EBBMS for the detection of access site related internal bleeding events during large-bore endovascular procedures.
- Trial name
- NCT03621202
- Testing
- Saranas Early Bird Bleed Monitoring System (EBBMS)
- Where
- 5 sites in United States
- Volunteers
- 66 people
- Sponsor
- Saranas, Inc.
Colorectal Adenomatous Polyps
I-scan for Adenoma Detection
This study is a randomized controlled trial to determine whether i-scan can improve the detection of conventional adenomas and sessile serrated adenomas/polyps.
- Trial name
- NCT02811419
- Testing
- i-scan, standard high-definition white light
- Where
- United States
- Volunteers
- 740 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Traumatic Brain Injury
Quantitative Automated Lesion Detection of Traumatic Brain Injury
The investigators propose to develop quantitative automated lesion detection (QALD) procedures to identify brain damage following traumatic brain injury more accurately than is possible with a normal magnetic resonance imaging…
- Trial name
- QALD (NCT01022307)
- Where
- United States
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Colorectal Cancer Screening
Promoting Informed Decisions About Cancer Screening in Older Adults
This project aims to examine the impact of different interventions designed to help individualize colorectal cancer (CRC) screening decisions in adults aged 76-85. Clinicians will be assigned by chance to one of two arms.
- Trial name
- PRIMED (NCT03959696)
- Testing
- Notification, Training
- Where
- 5 sites in United States
- Volunteers
- 536 people
- Sponsor
- Massachusetts General Hospital
Atrial Fibrillation
Efficacy of Optison Echo Contrast to Detect Thrombus in Left Atrial Appendage
The investigators intend to determine if using Optison echocardiography contrast increases sensitivity and specificity of detecting left atrial appendage thrombus in transesophageal echocardiography studies as opposed to standard…
- Trial name
- DOLOP (NCT01721447)
- Testing
- Optison echocardiography contrast agent
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Utah
Ovarian Cancer, Sentinel Node
Sentinel Node Detection in Clinical Early Stage Ovarian Cancer
As most cancers, ovarian cancer also spreads to regional lymph nodes. The concept of sentinel lymph node surgery is to see whether the cancer has spread to the very first lymph node or sentinel node (SN).
- Trial name
- SONAR (NCT01734746)
- Testing
- Tracerinjection
- Where
- Netherlands
- Volunteers
- 22 people
- Sponsor
- Maastricht University Medical Center
Cardiovascular Diseases
Role of Nitric Oxide in the Impact of Aging on Myocardial Remodeling
The purpose of this study is to determine, with Positron Emission Tomography (PET), the role of nitric oxide in the age-associated effect on fatty acid and glucose delivery on myocardial substrate metabolism.
- Trial name
- NCT00603720
- Testing
- L-NAME, L-Arginine, Phenylephrine
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Colonic Polyps, Colonic Neoplasms
Improving Bowel Preparation for Colonoscopy With a Simple Educational Card
The purpose of this study is to determine whether adding a simple educational card to standard pre-procedure instructions improves the quality of bowel preparation for colonoscopy.
- Trial name
- NCT00643682
- Testing
- Educational card
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- Boston Medical Center
Fetal Growth Retardation
Placental Lesions in Fetal Growth Restrictions
The purpose of this research study is to develop imaging methods to diagnose placental injury in pregnancies diagnosed with fetal growth restriction (FGR).
- Trial name
- NCT04839185
- Testing
- Ferumoxytol infusion, MRI scan
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Wisconsin, Madison
Schizophrenia, Bipolar Disorder
Early Detection and Intervention for the Prevention of Psychosis
EDIPP is a multisite trial of early identification and intervention to prevent the onset of psychosis in adolescents and young adults, carried out at six sites across the United States.
- Conditions
- Schizophrenia, Bipolar Disorder, Depression, Psychotic Disorders
- Trial name
- EDIPP (NCT00531518)
- Testing
- aripiprazole; fluoxetine; bupropion; sertraline; lamotrigine, Psychoeducational multifamily group treatment, Supported employment and education
- Where
- 6 sites in United States
- Volunteers
- 292 people
- Sponsor
- MaineHealth
Post-ERCP Acute Pancreatitis
Urine Trypsinogen 2 Dipstick for the Early Detection of Post-ERCP Pancreatitis
Post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) is the most common, serious complication of ERCP. More than 500,000 ERCP procedures are performed from which 25,000 cases of PEP occur in the U.S.A.
- Trial name
- NCT03098082
- Testing
- Actim Pancreatitis
- Where
- United States
- Volunteers
- 394 people
- Sponsor
- Indiana University
Carcinoma, Renal Cell, Kidney Neoplasms
Imaging Studies of Kidney Cancer Using 18F-VM4-037
Background: The drug 18F-VM4-037 is being tested for use in cancer imaging studies. It may help tumor tissue show up more clearly during scans.
- Trial name
- NCT01712685
- Testing
- 18F-VM4-037, PET/CT
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- National Cancer Institute (NCI)
Parkinson's
Apolipoprotein D (ApoD) In Human Serum As Marker Of Parkinson's Disease
In Italy affected people are 200,000 and every year Parkinson new cases are 10,000. Aging is the principle risk factor of Parkinson with the possibility of its development doubling every five years after 65.
- Trial name
- ApoD (NCT01467960)
- Where
- Italy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Privatklinik Villa Melitta
Prostate Cancer Detection
Zinc/PSA Ratio as a Novel Biomarker for Prostate Cancer Detection
Although Prostate Specific Antigen (PSA) is a useful marker for early detection of the prostate cancer, its specivity is not sufficient.
- Trial name
- NCT02013180
- Where
- Turkey (Türkiye)
- Volunteers
- 480 people
- Sponsor
- Bagcilar Training and Research Hospital
Mental Disorder, Schizophrenia
A Trial to Assess a Wearable Patch's Functioning to Detect Medication Ingestion
The primary purpose of the study is to evaluate the positive detection accuracy (PDA) and detection latency measures of the D-Tect patch.
- Conditions
- Mental Disorder, Schizophrenia, Major Depressive Disorder, Bipolar I Disorder
- Trial name
- NCT06372210
- Testing
- Abilify MyCite®, D-Tect Patch
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Lung Cancer
Testing of Computer Aided Detection Software for Riverain Medical Group
This is a clinical trial using retrospective data of two different software devices developed by Riverain Medical Group: Softview and OnGuard 5.0. The two studies will be run concurrently.
- Trial name
- NCT00906789
- Testing
- Software
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Prostate Cancer, Cancer of the Prostate
Adaptive Stereotactic Body Radiation Therapy to the Prostate and Pelvic Nodes With Simultaneous Integrated Boost to the MR-detected Nodule for Patients With High-risk and Unfavorable Intermediate-risk Prostate Cancer
This trial is a prospective clinical trial designed to demonstrate the safety and feasibility of whole-pelvis adaptive prostate stereotactic body radiation therapy (SBRT) with a tumor boost to the magnetic resonance (MR)-detected…
- Trial name
- NCT05628363
- Testing
- Ethos Varian treatment system, Adaptive stereotactic body radiotherapy, Androgen deprivation therapy
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Washington University School of Medicine
Low Back Disorder
MMG vs. EMG for Cortical Breach Detection
The purpose of this study is to determine how well mechanomyography (MMG) and electromyography (EMG) prevent cortical bone breaches, or the pinching of a nerve from screw placement, in patients having lower back surgery requiring…
- Trial name
- NCT05352048
- Testing
- Triggered Electromyography, Mechanomyography
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Francis Farhadi
Colonic Polyp
Detection of Colonic Polyps Via a Large Scale Artificial Intelligence (AI) System
Colonoscopy is the gold standard for detection and removal of precancerous lesions, and has been amply shown to reduce mortality.
- Trial name
- NCT04693078
- Testing
- AI polyp detection system based on deep learning
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shaare Zedek Medical Center