Clinical trials: Detection
Irritable Bowel Syndrome
Confocal Laser Endomicroscopy, IBS and Stress
After standard endomicroscopy with fluorescein to investigate for dysplasia in Barrett's esophagus the endoscope will be forwarded into the 2nd part of the duodenum.
- Trial name
- NCT02316132
- Testing
- Stress, Control
- Where
- Germany
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital Schleswig-Holstein
Neisseria Gonorrheae Infection
Performance, Acceptability, and Usability of a Novel Rapid Lateral Flow Test for Detecting Neisseria Gonorrhoeae in Pregnant and Symptomatic Women Attending Clinics in South Africa.
Previous studies of the Neisseria gonorrhoeae (NG) lateral flow assay (LFA) have shown promising results. In East London, South Africa, the LFA demonstrated a sensitivity of 80% in asymptomatic women.
- Trial name
- GO-SA (NCT07530406)
- Testing
- Novel Lateral Flow Assay for Neisseria gonorrhoeae
- Where
- South Africa
- Volunteers
- 1,239 people, healthy volunteers welcome
- Sponsor
- Foundation for Professional Development (Pty) Ltd
Thyroid Cancer
Use of 18F-PSMA-11 PET for Detection of Lesions in Iodine Refractory Thyroid Cancers
Determine the diagnostic value of 18F-PSMA-11 in patients with iodine refractory thyroid cancer.
- Trial name
- NCT05175404
- Testing
- PET/CT scan F18-PSMA-11
- Where
- Belgium
- Volunteers
- 8 people
- Sponsor
- University Hospital, Ghent
Carotid Stenosis, Carotid Artery Diseases
Embolic Signals Detection Study (Esds) in Candidates for Surgical Carotid Revascularisation
About 20% of strokes are caused by emboli deriving from a carotid plaque. In symptomatic patients with carotid stenosis grater than 70% the Carotid Endarterectomy (CEA) reduces stroke risk by about 75% and is generally accepted…
- Conditions
- Carotid Stenosis, Carotid Artery Diseases, Carotid Atherosclerosis, Carotid Artery Plaque
- Trial name
- NCT05134493
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Modena
Gastroenteropancreatic Neuroendocrine Tumors
Incremental Value of Delayed 68Ga-DOTATATE PET/MR in the Detection of Liver Metastases
68-Ga-DOTATATE is a radiotracer targeting somatostatin receptors (SSTR). In this study, we investigated the diagnostic efficacy of delayed ^68^Ga-DOTATATE PET/MR in patients with gastroenteropancreatic neuroendocrine tumors…
- Trial name
- NCT07898904
- Where
- China
- Volunteers
- 46 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Torticollis, Cervical Dystonia
Effects of Botulinum Toxin in Cervical Dystonia
Botulinum toxin injection in the contracting muscles has proven to be a safe and effective method of relieving pain and lessening dystonic posturing.
- Trial name
- NCT01056861
- Testing
- Botulinum Toxin A
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Alzheimer Disease, Mild Cognitive Impairment
Dementia Signal Development Study of Nautilus NeuroWave TM for the Detection of Dementia
This study is being performed to generate data regarding brain vibration /oscillation differences between individuals with dementia and normal controls.
- Conditions
- Alzheimer Disease, Mild Cognitive Impairment, Frontotemporal Lobar Degeneration, Memory Disorders
- Trial name
- NCT02333942
- Testing
- Nautilus NeuroWaveTM System
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Jan Medical, Inc.
Radiation Induced Lung Injury, Non Small Cell Lung Cancer
Hyperpolarized Noble Gas MRI Detection of Radiation-Induced Lung Injury
Lung cancer is the leading cause of cancer death in the world; each year lung cancer claims over 20 000 lives in Canada and more than one million lives globally (1).
- Trial name
- NCT03632369
- Testing
- Hyperpolarized xenon-129 MRI
- Volunteers
- healthy volunteers welcome
- Sponsor
- Thunder Bay Regional Health Research Institute
Prostate Cancer, Prostate Cancer Diagnosis
Cognitive Fusion Prostate Biopsy With Biparametric Magnetic Resonance in the Detection of Prostate Cancer
The goal of this prospective observational study is to evaluate the diagnostic precision of the Biparametric Magnetic Resonance Imaging (bpMRI) in the detection of clinically significant prostate cancer (PCa) in patients with…
- Trial name
- NCT05818631
- Testing
- fusion cognitive prostate biopsy
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- José Joaquín Mira
Transient Ischemic Attack, Atrial Fibrillation
Early Detection Of Atrial Fibrillation In Patients With Transient Ischemic Attack
The purpose of this study is to determine the frequency of atrial fibrillation in patients with transient ischemic attack (TIA).
- Trial name
- NOTICE (NCT02011256)
- Testing
- Implantable loop-recorder
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- University of Southern Denmark
Bloodstream Infection, Sepsis
Clinical Performance Study of Microbio InfectID-BSI for Detection of Bacteria and Yeast With Patient Blood Samples
The objective of the study is to determine the efficacy of the Microbio InfectID-BSI qPCR kit in a clinical laboratory environment using patient whole blood for pathogen detection and identification versus standard of care…
- Conditions
- Bloodstream Infection, Sepsis, Septic Shock
- Trial name
- IID-BSIqPCR (NCT06531031)
- Testing
- InfectID-BSI (Bloodstream Infection) qPCR Assay
- Where
- 8 sites in United States, Australia and 1 more
- Volunteers
- 1,500 people
- Sponsor
- Microbio Co Ltd
Ventilator Weaning
Echocardiographic Detection of Extravascular Lung Water Increase During Weaning From Mechanical Ventilation
Switching from positive airway pressure ventilation to spontaneous ventilation during weaning from mechanical ventilation, pulmonary edema may occur and in this case, doppler echocardiographic (U/S) indices of cardiac dysfunction…
- Trial name
- ECHOBAG (NCT02412202)
- Testing
- Monitoring of pulmonary oedema induced by weaning from mechanical ventilation
- Where
- Greece
- Volunteers
- 30 people
- Sponsor
- University of Thessaly
Hydrocephalus
Thermal Camera Detection of Ventriculoperitoneal Shunt Flow
There have been reports in the past of using thermal cameras to demonstrate flow in the tubing as a surrogate of proper shunt function.
- Trial name
- Infrared Shunt (NCT03451669)
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Pennsylvania
Prostatic Neoplasm
Detection Rate of Prostate Cancer in Men Undergoing MRI
To assess prostate cancer (PCa) detection rate in men undergoing magnetic resonance imaging (MRI) before planning prostate biopsy. Results will be stratified considering men with/without previous negative prostate biopsy.
- Trial name
- NCT04398173
- Testing
- multiparametric MRI
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- Fondazione del Piemonte per l'Oncologia
Lung Neoplasms, EGFR Gene Mutations
Osimertinib in First and Second Line Treatment of NSCLC Harboring EGFR Mutations From Circulating Tumor DNA
Treatment efficacy of osimertinib will be assessed in patients with lung cancer harboring activating epidermal growth factor receptor (EGFR) mutations (cohort 1) and those harboring T790M (cohort 2) which were detected from…
- Trial name
- LiquidLung-O (NCT02769286)
- Testing
- Osimertinib
- Where
- South Korea
- Volunteers
- 38 people
- Sponsor
- Chonnam National University Hospital
Ischemic Stroke, Brain Tumor
Confounding Factors in the Detection of Intracranial Hemorrhage With the Infrascanner
The investigators prospectively want to use the Infrascanner in patients with ischemic stroke, patients with brain surgery, patients with brain tumors, patients with intracranial hemorrhage and patients with a normal CT scan of…
- Conditions
- Ischemic Stroke, Brain Tumor, Brain Surgery, Intracranial Hemorrhage
- Trial name
- NCT02809651
- Testing
- Infrascanner
- Where
- Belgium
- Volunteers
- 89 people
- Sponsor
- Ziekenhuis Oost-Limburg
Diagnoses Disease
Early Detection of Endometrial/Ovarian Cancer and Hereditary Predisposition of These Cancers
Early stage high-grade cancer, endometrial and ovarian, has few, if any, symptoms or signs. When symptoms appear, the disease is commonly in advanced stage meaning it has left the gynaecological organs and metastasized to the…
- Trial name
- NCT04891029
- Testing
- DOvEEgene test
- Where
- 2 sites in Canada
- Volunteers
- 5,600 people, healthy volunteers welcome
- Sponsor
- McGill University
Pancreatic Cancer, Pancreatic Neoplasms
A Pancreatic Cancer Screening Study in Individuals With New-Onset or Deteriorating Diabetes Mellitus
The main goal of this study is to explore the relationship between new-onset diabetes mellitus/deteriorating diabetes and a subsequent diagnosis of pancreatic cancer.
- Conditions
- Pancreatic Cancer, Pancreatic Neoplasms, Diabetes Mellitus
- Trial name
- PANDOME (NCT03937453)
- Testing
- MRI/MRCP
- Where
- 2 sites in United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Nuvance Health
High Risk (Above Average) Subjects, Non Compliant Patients for Colo Rectal Cancer [CRC] Screening
Evaluation of C-Scan System in Providing Structural Information and Detection of Polypoid Lesions in High Risk Subjects
The purpose of this study is to establish the efficacy of Check-Cap's C-Scan System in providing structural information on colonic polypoid lesions and masses, as an adjacent tool to Feacal Immunochemical Test [FIT] in high risk…
- Conditions
- High Risk (Above Average) Subjects, Non Compliant Patients for Colo Rectal Cancer [CRC] Screening, Counterindicated Patients for Colonoscopy
- Trial name
- NCT03356002
- Testing
- C-Scan System
- Where
- 7 sites in Israel
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Check-Cap Ltd.
Lung Cancer (Diagnosis), Pulmonary Nodule Persistent
Multi-omics Detection Techniques for Differentiating Benign and Malignant Pulmonary Nodules
Research objective: To explore the clinical application effect of multi-omics detection based on flow cytometry analysis, single-cell data and images combined with clinical features in differentiating the benign and malignant…
- Trial name
- NCT07047573
- Testing
- PBMCS were isolated from the peripheral blood of hospitalized patients with pulmonary nodules and incubated with nanoparticles loaded with tumor antigens for a specific period of time to detect cancer
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Zhao Jun
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