Clinical trials: Detection
Portal Hypertension, Cirrhosis
Esophageal Capsule Endoscopy in Children
The portal hypertension (PHT) is the main complication in patients presenting with cirrhosis. It can be the direct cause of bleeding by rupture of the esophageal or gastric varices and can also contribute to the development of…
- Trial name
- PREVOCAP (NCT01551966)
- Testing
- Wireless esophageal capsule endoscopy ( PillCam Eso2)
- Where
- 7 sites in France
- Volunteers
- 100 people
- Sponsor
- Hospices Civils de Lyon
Esophageal Squamous Cell Carcinoma, Squamous Cell Carcinoma of the Head and Neck
The Role of Chromoendoscopy in the Early Detection of Esophageal Cancer in Patients With Prior Head and Neck Cancers
This study evaluates the role of narrow band imaging (NBI) endoscopy compared with Lugol chromoendoscopy in the early detection of esophageal cancer in patients with prior head and neck cancers.
- Trial name
- NCT02435602
- Testing
- NBI endoscopy, Lugol chromoendoscopy
- Where
- Poland
- Volunteers
- 294 people
- Sponsor
- Maria Sklodowska-Curie National Research Institute of Oncology
Myocardial Infarction, Cardiac Arrest
Troponin-T for Detection of Perioperative Cardiovascular Events
We will conduct a prospective cohort study evaluating the incidence of and optimal risk estimation model for major perioperative cardiovascular events in consecutive patients undergoing noncardiac surgery at the 'Herlev…
- Trial name
- VISION-pilot (NCT00443989)
- Where
- 2 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Artificial Intelligence
The Accuracy of Detection of Artificial Intelligence Second Mesio-buccal Canal of Maxillary First Molars on CBCT Images
CAD systems are computer applications that assist in the detection and/or diagnosis of diseases by providing an unbiased "second opinion" to the image interpreter, aiming at improving accuracy and reducing time for analysis.
- Trial name
- NCT05340140
- Testing
- deep learning model
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Breast Cancer
Infrared Imaging (Breast Scan IR) for Early Breast Cancer Detection
This protocol will evaluate a new non-invasive infrared imaging system as an adjunctive tool for breast cancer detection that has been approved by the FDA. The technology and device have been developed by Infrared Sciences Corp.
- Trial name
- NCT00195026
- Testing
- Infrared Breast Scan
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Weill Medical College of Cornell University
Hypertension, Pulmonary, Hypertension;Pulmonary;Primary
Endtidal Carbon Dioxide for Earlier Detection of Pulmonary Hypertension
Measurement of the endtidal carbon dioxide by capnography to exclude or to ensure the diagnosis pulmonary hypertension. The aim of the study is to obtain an endtidal carbon dioxide cut-off value for the diagnostic algorithm for…
- Conditions
- Hypertension, Pulmonary, Hypertension;Pulmonary;Primary, Chronic Thromboembolic Pulmonary Hypertension, Vascular Diseases
- Trial name
- EARLIER (NCT03388476)
- Testing
- Capnography
- Where
- Germany
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Giessen
Stroke
Micro-embolic Signals Detection With Transcranial HOLter in Acute Ischemic STroke
In acute ischemic stroke, the identification of an etiology is of major importance to prevent recurrence by providing the best treatment.
- Trial name
- HOLISTER (NCT02762552)
- Testing
- Transcranial-holter monitoring
- Where
- France
- Volunteers
- 244 people
- Sponsor
- University Hospital, Bordeaux
Intensive Care, Brain Injuries
Use of Critical-Care Pain Observation Tool and Bispectral Index for Detection of Pain in Brain Injured Patients
Brain injured patients are at high risk of pain due to the illness itself and a variety of nociceptive procedures in intensive care unit.
- Trial name
- NCT03368326
- Testing
- Critical-Care Pain Observation Tool (CPOT)
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Capital Medical University
Osteonecrosis of the Jaw, Bisphosphonate Induced, Osteonecrosis of the Jaw, Bisphosphonate Related
Initial Management of MRONJ Stages I and II, a Clinical Trial With Detection of Salivary Biomarkers
Medication-related osteonecrosis of the jaw (MRONJ) is a serious complication in patients receiving antiresorptive therapies, such as Bisphosphonates and Denosumab.
- Trial name
- NCT04584840
- Testing
- Surgical treatment
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Fundació d'investigació Sanitària de les Illes Balears
Gastrointestinal Bleeding
Computed Tomography in Gastrointestinal Bleeding
Gastrointestinal bleeding represents a serious clinical problem and a common cause of hospitalisation with a mortality rate of 6-10% for upper Gastrointestinal bleeding and of 4% for lower Gastrointestinal bleeding requires a…
- Trial name
- NCT03243240
- Testing
- mutlidetector computed tomography
- Volunteers
- 30 people
- Sponsor
- Assiut University
Lifestyle-Related Disorder
An Adjusted Preventive Program Against Lifestyle Related Diseases
A large proportion of the Danish population leads an unhealthy lifestyle. The associated surge in lifestyle-related disease (LRD) represents a significant health and economic burden for the individual as well as society.
- Trial name
- TOFpilot2 (NCT03913585)
- Testing
- Lifestyle intervention
- Where
- 4 sites in Denmark
- Volunteers
- 4,800 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Arterial Hypertension
Arterial Hypertension in Men in the Warmia and Masuria Region
The primary aim of the study is to define the prevalence of arterial hypertension and risk factors of its development in an unselected group of Polish men from the region of Warmia and Mazury, considered as one of the most…
- Trial name
- ProM (NCT03559608)
- Where
- Poland
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- University of Warmia and Mazury
Glioma, Malignant, Embryonal Tumor
Integrated Analysis of Therapy Response and Resistence in Embryonal Tumors and Gliomas
The treatment of adolescents and young adults (AYA, 15 to 39 years) with malignant intra-axial CNS parenchymal tumors such as IDH-mutated gliomas, medulloblastomas and ependymomas is still not curative in all cases.
- Conditions
- Glioma, Malignant, Embryonal Tumor, Medulloblastoma, Ependymoma
- Trial name
- BZKF-AYA (NCT06323408)
- Testing
- Tissue, blood, cerebrospinal-spinal fluid
- Volunteers
- 72 people
- Sponsor
- University Hospital Regensburg
Breast Cancer
Recurrence Score-guiding Chemotherapy in Non-pCR HR Positive HER2 Negative Breast Cancer After Neoadjuvant Therapy
The luminal subtype of breast cancer means hormone receptor positive, human epidermal growth factor receptor 2 negative (HR+HER2-), which counted 60%-70% of breast cancer but achieve low pathologic complete response (pCR) rate…
- Trial name
- RSBNAT (NCT03638648)
- Testing
- Capecitabine
- Volunteers
- 80 people
- Sponsor
- Zhejiang Cancer Hospital
Antiphospholipid Syndrome
Measurement of Anti-dsDNA by Both CLIFT & ELISA
detection of anti-ds DNA in patients with rheumatic diseases by two methodes : immunofluorescence \& ELISA
- Trial name
- NCT03303508
- Testing
- anti-ds DNA
- Volunteers
- 100 people
- Sponsor
- Assiut University
Small Intestine Disease, Small Intestine Cancer
Prospective Collection of PillCam SB3 Videos and Raw Data Files for Future Developments (SODA)
Observational, Multicenter, Post-market, Minimal risk, Prospective data collection of PillCam SB3 videos (including PillCam reports) and raw data files and optional collection of Eneteroscopy reports
- Conditions
- Small Intestine Disease, Small Intestine Cancer, Small Intestinal Ulcer Bleeding, Small Intestine Obstruction
- Trial name
- SODA (NCT03771508)
- Where
- 30 sites in United States
- Volunteers
- 3,712 people
- Sponsor
- Medtronic - MITG
Cervical Cancer, Endometrial Cancer
Value of Diffusion Weighted Magnetic Resonance Imaging in Detection of Recurrent Disease in Surgically Treated Cervical and Endometrial Cancer Patients
Endometrial and cervical cancers are one of the most common malignancies seen in females. Identification of recurrent disease in early phases of treatment carries a primary importance on the outcome of patients.
- Trial name
- NCT01710085
- Testing
- Diffusion weighted MRI (DW- MRI)- Philips Achieva 3.0T X, Netherlands, 2011
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Uludag University
Arrhythmia Atrial, Stroke
Atrial Fibrillation Detection: 24 Hour Study
Aims Approximately 20-25% of strokes are of cardioembolic origin, atrial fibrillation (AF) being a significant cause of cardioembolic strokes. AF is often symptomless and intermittent, making its detection a clinical challenge.
- Trial name
- AFIB24h (NCT03507335)
- Testing
- chest strap and PPG-device for monitoring the rhythm
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- Kuopio University Hospital
Coronary Artery Disease
Detection of Coronary Artery Disease Using Analysis of High Frequency QRS: The HyperQ Registry
This will be a registry study that will enroll patients referred for an ECG treadmill test with nuclear myocardial perfusion imaging (MPI).
- Trial name
- HyperQ (NCT01325467)
- Where
- 3 sites in United States
- Volunteers
- 900 people
- Sponsor
- BSP Biological Signal Processing Ltd.
Vital Signs
Detection of Deterioration by SNAP40 Versus Standard Monitoring in the ED
In recent years there has been increasing focus on the earlier detection of deterioration in the clinical condition of hospital patients with the aim of instigating earlier treatment to reverse this deterioration and prevent…
- Trial name
- SNAP40ED (NCT03179267)
- Testing
- SNAP40
- Where
- United Kingdom
- Volunteers
- 250 people
- Sponsor
- NHS Lothian
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