Clinical trials: Detection
Congenital Deafness, Suspicion of Congenital Deafness
NGS Assessment of Congenitally Deafned Children and Neonatal Deafness Screnning
To assess the diagnostic value of NGS screnning in prelingually deafned children using a new designed chip, and to evaluate its interest in a the neonatal screening program for ddetecting congenitally deafned children.
- Trial name
- GHELP (NCT04350619)
- Testing
- Genetic screening. No therapeutic intervention
- Where
- France
- Volunteers
- 220 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Prostate Cancer
Assessing Circulating Tumor Cell as a Biomarker for Prostate Cancer Detection in Patients With Gray Zone PSA Level
Prostate cancer screening with PSA is plagued by high rate of unnecessary prostate biopsies, especially in the "gray zone" (4.00ng/ml e 10.99ng/ml).
- Trial name
- NCT03488706
- Where
- Taiwan
- Volunteers
- 500 people
- Sponsor
- CellMaxLife
Congenital Hyperinsulinism
18FluoroLDOPA PET Imaging for the Detection and Localization of Focal Congenital Hyperinsulinism
The goal of this project is to determine the role of FDOPA/PET as a pre-operative diagnostic imaging procedure for differentiating focal and diffuse forms of congenital hyperinsulinism and locating focal lesions in the pancreas…
- Trial name
- DOPA PET (NCT04205604)
- Testing
- 18F-Fluoro Dopa Imaging
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Miguel Pampaloni
Leukemia
Analysis of Blood and Bone Marrow to Detect Residual Disease in Patients With Previously Treated Hairy Cell Leukemia
RATIONALE: Diagnostic procedures that detect residual disease may predict disease relapse in patients who have hairy cell leukemia.
- Trial name
- NCT00005619
- Testing
- polymerase chain reaction, flow cytometry, immunohistochemistry staining method
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Northwestern University
Hepatocellular Carcinoma, Liver Cancer
FAST-IRM for HCC suRveillance in pAtients With High risK of Liver Cancer.
Intro: Hepatocellular carcinoma (HCC) is the 6th leading cause of cancer worldwide. In France, more than 10,000 new cases are identified each year.
- Conditions
- Hepatocellular Carcinoma, Liver Cancer, Cirrhosis, Chronic Liver Disease
- Trial name
- FASTRAK (NCT05095714)
- Testing
- Liver ultrasound and fast-MRI, Liver ultrasound
- Where
- France
- Volunteers
- 944 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hepatocellular Carcinoma (HCC)
AI-Guided Surveillance and Curative Salvage of Recurrence After Hepatocellular Carcinoma Resection or Ablation
Hepatocellular carcinoma, the most common type of primary liver cancer, can recur after liver resection or thermal ablation performed with curative intent.
- Trial name
- HCC-AI-RECLAIM (NCT07732504)
- Testing
- Artificial Intelligence-Guided Risk-Adapted Surveillance, Fixed-Interval Surveillance
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Tongji Hospital
Adenoma, Polyps
Prospective Trial to Compare ADR of G-EYE™ Colonoscopy With Standard Colonoscopy
The purpose of this study is to compare the adenoma detection rate (ADR) of the G-EYE™ colonoscopy with that of standard colonoscopy.
- Conditions
- Adenoma, Polyps, Colorectal Cancer
- Trial name
- NCT02545699
- Testing
- G-EYE™ Colonoscopy, Standard Colonoscopy
- Where
- Israel
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Smart Medical Systems Ltd.
Catheter-Related Infections, Pressure Injury
Pilot Testing a Patient Safety Display in the Hospital Setting
This is a feasibility pilot study to introduce and evaluate an intervention designed to increase clinician awareness of their patients' urinary catheters, vascular catheters, and pressure injuries.
- Trial name
- NCT03950921
- Testing
- Patient Safety Display
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- University of Michigan
Chronic Hepatitis b
A Study on the Consistency Evaluation of Digital PCR Technology for Quantitative Detection of HBV Nucleic Acid
The research plan aims to evaluate the consistency of the digital PCR-based hepatitis B virus nucleic acid quantification technique with the existing Roche qPCR-based detection method.
- Trial name
- NCT07684209
- Testing
- the results were classified according to concentration levels
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beijing Municipal Administration of Hospitals
Adrenal Hyperplasia, Congenital, Congenital Hypothyroidism
Clinical Evaluation of NeoPlex4 Assay and NeoPlex System
The purpose of this study is to assess the agreement of clinical performance between the proposed NeoPlex 4 assay and NeoPlex System and the comparator devices in clinical use in newborn screening programs for detection of T4…
- Conditions
- Adrenal Hyperplasia, Congenital, Congenital Hypothyroidism, Cystic Fibrosis
- Trial name
- NCT01488721
- Where
- 3 sites in United States
- Volunteers
- 7,462 people, healthy volunteers welcome
- Sponsor
- Luminex Corporation
Colorectal Adenoma
Detection of Colorectal Adenomas in Côte-d'Or
Previous studies have shown geographic disparities in the detection of colorectal adenomas in Côte-d'Or, with an impact of the distance from the general practitioner and an ecological deprivation index (EDI).
- Trial name
- DACCOR (NCT02859714)
- Testing
- screening data
- Where
- France
- Volunteers
- 11,600 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Breast Cancer
Digital Mammography for the Detection and Preoperative Staging of Breast Cancer
Breast tumors are normally seen with mammography or ultrasound without the use of a dye but the size and extent of the tumor may be hard to see.
- Trial name
- NCT01086514
- Testing
- Dual Energy Contrast Enhanced Digital Mammography (DE CEDM)
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Healthy
Plant miRNAs In Human Plasma After Broccoli Consumption
Nutritional clinical study to evaluate the absorption and presence of exogenous miRNAs from broccoli in plasma and peripheral blood mononuclear cells (PBMCs) and to determine their possible implication in the modulation of fecal…
- Trial name
- NCT07456267
- Testing
- Broccoli consumption
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- IMDEA Food
Iatrogenesis, Clinical Vignettes
Evaluation of the POSOS Device for Iatrogenesis Detection in Clinical History? A Vignettes Study
This study is a multicenter evaluation of diagnostic performance using simulated clinical vignettes. It aims to test the effectiveness of the POSOS app in detecting drug-induced iatrogenesis in urgent medical situations, an issue…
- Conditions
- Iatrogenesis, Clinical Vignettes, Diagnostic Performance Study, Medical Information Search
- Trial name
- YGenHiVi (NCT05952193)
- Where
- France
- Volunteers
- 85 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Diabetic Retinopathy, Glaucoma
AI for the Detection of Retinal Disease and Glaucoma in Patients With Diabetes Mellitus in Primary Care
Background: Diabetic retinopathy (DR) is one of the most important causes of blindness worldwide, especially in developed countries.
- Conditions
- Diabetic Retinopathy, Glaucoma, Age-Related Macular Degeneration, Choroidal Nevus
- Trial name
- NCT04132401
- Testing
- algorithm
- Where
- Spain
- Volunteers
- 902 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Deep Venous Thrombosis
Radial, Sequential Compression Device Deep Venous Thrombosis Detection Study
The purpose of this study is to evaluate the effectiveness of a new leg compression device in preventing post-surgical deep vein thrombosis (blood clot) that can occur after major and complex spine surgery.
- Trial name
- NCT04232501
- Testing
- Cirvo Compression device
- Where
- United States
- Sponsor
- Stanford University
Myeloproliferative Neoplasm, Optical Genome Mapping
Evaluation of Optical Genome Mapping in Phi Negative Myeloproliferative Neoplasia in the Detection of Acquired Cytogenetic Abnormalities
Standard cytogenetics (CBA +/- FISH) is of diagnostic and prognostic interest in Ph- MPN. However, its value is limited by the low frequency of detected abnormalities.
- Conditions
- Myeloproliferative Neoplasm, Optical Genome Mapping, Cytogenetics, Clonality
- Trial name
- MYELOCARTOCH (NCT05714592)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Arrhythmias
Non Invasive Arrhythmia Detection in Hospital Settings
This is a prospective, single center, non-randomized study to evaluate the arrhythmia detection performance during ventricular events.
- Trial name
- EVE (NCT00919087)
- Testing
- Avivo System
- Volunteers
- 25 people
- Sponsor
- Corventis, Inc.
Human Papilloma Virus Infection
Standard Operating Procedures for Anti-HPV (Human Papillomavirus) Antibody Detection in First-void Urine (AB-SOP Study)
The aim of the study is to develop robust analytical protocols for first-void urine sample preparation and antibody assays to monitor natural and/or vaccine induced immunity against HPV (Human Papillomavirus).
- Trial name
- AB-SOP (NCT02714114)
- Testing
- First-void urine collection, Blood draw
- Where
- Belgium
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen
Visceral Leishmaniasis
Improved Case Detection and Vector Control for Visceral Leishmaniasis
Visceral leishmaniasis (VL) also known as kala-azar is a public health problem in Bangladesh. Since 2005 a national kala-azar elimination program is going on in the country.
- Trial name
- NCT03269006
- Testing
- Inesfly Paint, IDWL (1m), ITN (KO-Tab 123)
- Where
- Bangladesh
- Volunteers
- 202 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.