Clinical trials: Detection
Cancer
The Vallania Study: A Case Control Study for the Development of Multiomics Blood Tests for Cancer Screening
This protocol is a case-control, multicenter, diagnostic study to collect blood samples to support the development of blood-based screening tests for multiple cancers.
- Trial name
- NCT05254834
- Testing
- Freenome Test
- Where
- 68 sites in United States
- Volunteers
- 7,435 people, healthy volunteers welcome
- Sponsor
- Freenome Holdings Inc.
Coronary Artery Disease
ST Segment Detection Study
The purpose of ST Detect study is to evaluate whether naturally occurring spontaneous coronary events and exercise induced cardiac ischemia, give rise to detectable changes on intracardiac electrogram (EGM) signals in patients…
- Trial name
- ST Detect (NCT00930969)
- Testing
- ICD
- Where
- 25 sites in United States, Austria and 5 more
- Volunteers
- 175 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Contrast Media, Computed Tomography
Multiple Arterial Phase Computed Tomography Examination to Improve Detection of Tumors in the Liver and Pancreas
To examine inter-subject variations of optimal late arterial phase contrast-enhancement defined as the greatest difference in contrast attenuation of hepatocellular carcinoma (HCC) compared to background liver parenchyma resp.
- Conditions
- Contrast Media, Computed Tomography, Imaging, Pancreatic Cancer
- Trial name
- NCT04813432
- Testing
- Computed Tomography of the Abdomen
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Karolinska Institutet
Lung Non-Small Cell Carcinoma, Thoracic Cancer
Qualitative Study on Detection & Tx of NSCLC in Pts w/ a History of Alcohol or SUD
This study will attempt to identify social facilitators and barriers to detection and treatment of non-small cell lung cancer in order to learn how a history of substance abuse or alcohol use impacts care for non-small cell lung…
- Trial name
- NCT07186699
- Testing
- Non-Interventional Study
- Where
- 2 sites in United States
- Volunteers
- 45 people
- Sponsor
- University of Southern California
Neurologic Disorder
Intracorporeal Nanocomposites and Neurological Disorders in Fulgurates (FulgurnanoF)
Objective: To demonstrate the presence of bioresistant intracorporeal carbon-based nanocomposites in subjects exposed to a fulguration, in the immediate aftermath of this fulguration and 24 months (+/- 6 months) after the…
- Trial name
- Fulgurnano (NCT04380194)
- Testing
- nano-composite screening
- Where
- 5 sites in France
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Pleural Effusion
Validity of Pleural Effusion Detection Software
The Chang Gung Pleural Effusion Detection Software is a medical software that can automatically detect whether there is a pleural effusion in Chest X-Ray.
- Trial name
- NCT05903287
- Testing
- Chang Gung Pleural Effusion Detection Software
- Where
- Taiwan
- Volunteers
- 282 people
- Sponsor
- Chang Gung Memorial Hospital
Atrial Fibrillation, Heart Failure
Insertable Cardiac Monitor for Primary Atrial Fibrillation Detection in High-Risk Heart Failure Patients
Patients with heart failure (HF) represent a large population of patients who are at high risk for complications related to undiagnosed atrial fibrillation (AF).
- Trial name
- ASSERT-AF (NCT04818645)
- Testing
- ASSERT Insertable Cardiac Monitor, Conventional Management and monitoring
- Where
- United States
- Volunteers
- 477 people
- Sponsor
- University of Rochester
Mammogram Uptake, Breast Cancer
Trial to Evaluate the Impact of Various Pragmatic Interventions to Increase Mammography Uptake Among Defaulted Repeat Screeners in Singapore
Breast cancer is the most common cancer among women in Singapore, accounting for nearly 30% of all female cancers. While regular biennial mammography can reduce mortality, screening rates in Singapore remain low at 34.7%; well…
- Conditions
- Mammogram Uptake, Breast Cancer, Breast Neoplasm, Early Detection of Cancer
- Trial name
- REMIND1 (NCT07651345)
- Testing
- Arm 2: One mailed reminder, Arm 3: Two mailed reminders, Arm 4: Mailed reminder with prescheduled appointment
- Where
- Singapore
- Volunteers
- 12,750 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Active Tuberculosis
miRNA in Sweat, a Novel Digital Biomarker for Detection of Active Tuberculosis (TB)
The detection of miRNA (non-coding ribonucleic acid) in the blood in the context of active tuberculosis is an innovative approach to the detection of new disease-specific biomarkers.
- Trial name
- NCT05048381
- Testing
- Next Generation Sequencing
- Sponsor
- University Hospital, Basel, Switzerland
Preterm Delivery, Pregnant Women
Study of Antenatal Model to Prevent Preterm Delivery
The purpose of this study is to determine whether antenatal model in vaginosis are effective in preventing vaginal infection and preterm delivery
- Conditions
- Preterm Delivery, Pregnant Women, Antenatal Care Model
- Trial name
- AACP (NCT01232192)
- Testing
- antenatal model
- Where
- Indonesia
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Showa University
Plasmodium Falciparum Malaria
Rapid Diagnostic Tests for Assessment of Initial Clearance and Detection of Recurrent Malaria Infections
The aim of the study was to follow clearance of malaria infections and detection of new malaria episodes after initiation of antimalarial treatment in Tanzanian children.
- Trial name
- NCT01843764
- Testing
- HRP2 and LDH based rapid diagnostic tests for P.falciparum
- Where
- 2 sites in Tanzania
- Volunteers
- 53 people
- Sponsor
- Anders Björkman
Chronic Pancreatitis, PDAC - Pancreatic Ductal Adenocarcinoma
Early Detection of PDAC in Patients With Chronic Pancreatitis
The goal of this study is to find simple warning signs that doctors can use to spot pancreatic cancer early in people who have chronic pancreatitis.
- Trial name
- NCT07104864
- Testing
- histopathological confirmation
- Where
- China
- Volunteers
- 359 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Infectious Diseases
Specificity Study of Diagnostic for Early Detection of Dengue Infection
This study assesses the specificity of DENV Detect™ NS1 ELISA versus standard reference tests (e.g. PCR or viral culture) for dengue diagnosis in the US.
- Trial name
- NCT02107677
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- InBios International, Inc.
Anesthesia
Validation of Nicom Device to Measure Stoke Volume Variation
The purpose of this study is to evaluate the ability of NICOM (Noninvasive cardiac output monitor) to detect stroke volume variation induced by leg raising or fluid expansion during surgery
- Trial name
- NICOM-VAL (NCT02485457)
- Testing
- Volume loading, Ringer solution
- Where
- 2 sites in France
- Volunteers
- 2 people
- Sponsor
- Hopital Foch
Prostate Cancer
Single-center Trial for the Validation of High-resolution Transrectal Ultrasound (Exact Imaging Scanner ExactVu) for the Detection of Prostate Cancer
The primary objective of this study is to evaluate the performance of HR-TRUS in detection of prostate cancer lesions relative to whole mount section after radical prostatectomy as the reference.
- Trial name
- EXACTVU (NCT03679819)
- Testing
- HR-TRUS
- Where
- France
- Volunteers
- 32 people
- Sponsor
- Institut Paoli-Calmettes
Cognitive Impairment (CI)
Detect CI (Cognitive Impairment) Study
This is a prospective multicenter cohort study which will evaluate rapid (administration time ≤ 5 minutes) cognitive screening tools that can be administered preoperatively in older patients undergoing noncardiac surgery.
- Trial name
- CI (NCT06030765)
- Where
- 2 sites in Canada
- Volunteers
- 383 people
- Sponsor
- University Health Network, Toronto
Atrial Fibrillation
Accuracy of Rhythm Detection by a Wearable Smart Watch for Cardiac Arrhythmias (The WATCH-RHYTHM Study)
It is an attempt to see the reliability of the Wearable Smart Watch in identifying atrial fibrillation and other arrhythmias compared to the data detected from ILRs.
- Trial name
- NCT04499807
- Testing
- AFib detection with wearable smart watch
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Kansas City Heart Rhythm Research Foundation
Subject Presenting Wheeze, COPD
Wheeze Detection Using Aevice Medical Device
The primary objective of this study is to determine if Aevice Medical Device can detect wheeze as accurately as a physician through auscultation.
- Conditions
- Subject Presenting Wheeze, COPD, Asthma
- Trial name
- NCT05194436
- Testing
- AeviceMD
- Where
- Singapore
- Volunteers
- 35 people
- Sponsor
- Aevice Health Pte. Ltd.
Hyperactive Delirium, Hypoactive Delirium
A Pilot Study of "Stanford Proxy Test for Delirium" (S-PTD)
Although there are several tools available for the screening of delirium among the medically ill, they all have some limitations.
- Conditions
- Hyperactive Delirium, Hypoactive Delirium, Mixed Type Delirium
- Trial name
- NCT03954769
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Stanford University
Maculopathy
" En Face " OCT's Contribution in the Detection of Macular Retinal Toxicity Signs Linked to the Chronic Treatment of Synthetic Antimalarials
The maculopathy induced by the retinal toxicity of the synthetic antimalarials must be detected at the infra-clinical state, when it can still be reversible.
- Trial name
- OCTAPS (NCT02805686)
- Testing
- spectral domain optical coherence tomography, multifocal electroretinogram
- Volunteers
- 45 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
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