Clinical trials: Detection
Melanoma (Skin)
Interferon Alfa-2b in Treating Patients With Melanoma and Early Lymph Node Metastasis
RATIONALE: Interferon alfa-2b may interfere with the growth of cancer cells. PURPOSE: Randomized phase III trial to study the effectiveness of interferon alfa-2b in treating patients who have melanoma with early lymph node…
- Trial name
- NCT00004196
- Testing
- recombinant interferon alfa, lymphangiography, Observation
- Where
- 4 sites in United States
- Volunteers
- 3,000 people
- Sponsor
- University of Alabama at Birmingham
Gingival Inflammation, Machine Learning
Artificial Intelligence (AI)-Powered Thermal Imaging for Gingival Inflammation Detection
This study investigates a novel approach for detecting gingival inflammation using thermal imaging and artificial intelligence (AI).
- Conditions
- Gingival Inflammation, Machine Learning, Thermal Imaging
- Trial name
- NCT06830161
- Testing
- Gingival Thermal Images
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Gazi University
Tourette Syndrome
Tourette Deep Brain Stimulation (DBS) Target Detection & Suppression
The investigators will implant and monitor 8 research subjects with a subcortical closed-loop system for detection and suppression of tics in subjects with medically refractory debilitating Tourette Syndrome.
- Trial name
- NCT05371041
- Testing
- Medtronic Percept Neurostimulator
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Florida
Position, Colonoscopy
Dynamic Position Change in Colonic Adenoma Detection
There was an only single operator study reporting dynamic position change during colonoscopy withdrawal significantly improved polyp and adenoma detection.
- Conditions
- Position, Colonoscopy, Adenoma
- Trial name
- NCT01366079
- Testing
- Position change, Left lateral
- Where
- South Korea
- Volunteers
- 1,072 people
- Sponsor
- The Catholic University of Korea
Non Invasive Diagnosis of Glioma
Non Invasive IDentification of Gliomas With IDH1 Mutation
The recurrent mutation IDH1Arg132His leads to the cellular accumulation of D-2-hydroxyglutarate (2-HG), thus representing a diagnostic marker (this change is almost specific for gliomas) and prognostic (mutated gliomas have…
- Trial name
- IDASPE (NCT01703962)
- Where
- France
- Volunteers
- 6 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Prostate Cancer
Dose Escalation to Dominant Intraprostatic Lesions (DIL) With MRI-TRUS Fusion High Dose Rate (HDR) Prostate Brachytherapy
The Magnetic Resonance (MR) provides high resolution of soft tissue images allowing an appropriate assessment of the local extent of the disease.
- Trial name
- BRAPROST (NCT01909388)
- Testing
- MRI-TRUS fusion guided real time HDR
- Where
- Spain
- Volunteers
- 15 people
- Sponsor
- Alfonso Gomez-Iturriaga
Hypertrophic Cardiomyopathy
A Study of Artificial Intelligence ECG With ECG Devices to Detect Hypertrophic Cardiomyopathy Distinct From Athlete's
The purpose of this study is to evaluate the AI-ECG algorithm for HCM in detecting HCM and in differentiating it from athlete's using not only the standard 12-lead ECG, but also ECGs obtained with the Apple Watch and Alivecor…
- Trial name
- NCT06290570
- Testing
- 12-Lead ECG, Apple Smart Watch Single Lead ECG, AliveCor KardiaMobile 6-Lead ECG
- Where
- United States
- Volunteers
- 183 people
- Sponsor
- Mayo Clinic
Mouth Diseases
Optical Sensor for Photodynamic Detection of Oral Pathology
Overall objective of this work is to develop better ways of detecting, diagnosing and measuring oral diseases and structures using light and optical approaches.
- Trial name
- NCT00540774
- Testing
- detection of oral pathology
- Where
- United States
- Volunteers
- 1,004 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Breast Cancer Screening
Application of CfDNA Methylation Detection in Auxiliary Diagnosis of Breast Cancer
The purpose of this study is to construct an auxiliary diagnostic model for breast cancer by methylation markers. The study will collect blood and tissue samples from participants with breast cancer and benign disease for…
- Trial name
- NCT06876610
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Geneplus-Beijing Co. Ltd.
CTEPH, Pulmonary Embolism
Symptom-related Screening for Early Detection of CTEPH.
Routine screening for Chronic thromboembolic pulmonary hypertension (CTEPH) i after PE is not supported by current evidence and guidelines.
- Conditions
- CTEPH, Pulmonary Embolism, Symptoms and Signs, Dyspnea
- Trial name
- NCT03953560
- Testing
- dyspnea grade ≥ II according NYHA-WHO
- Where
- 16 sites in Spain
- Volunteers
- 646 people
- Sponsor
- Luis Jara-Palomares, MD
Breast Cancer
What Are the Benefits and Harms of Risk Stratified Screening in the NHS Breast Screening Programme: Study Protocol
This study aims to identify key benefits and harms of integrating risk stratification (the BC-Predict intervention) into the NHS Breast Screening Programme.
- Trial name
- NCT04359420
- Testing
- BC-Predict, NHS Breast Screening Programme
- Where
- United Kingdom
- Volunteers
- 32,298 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Schizophrenia, Bipolar Disorder
Early Detection and Intervention for the Prevention of Psychosis
EDIPP is a multisite trial of early identification and intervention to prevent the onset of psychosis in adolescents and young adults, carried out at six sites across the United States.
- Conditions
- Schizophrenia, Bipolar Disorder, Depression, Psychotic Disorders
- Trial name
- EDIPP (NCT00531518)
- Testing
- aripiprazole; fluoxetine; bupropion; sertraline; lamotrigine, Psychoeducational multifamily group treatment, Supported employment and education
- Where
- 6 sites in United States
- Volunteers
- 292 people
- Sponsor
- MaineHealth
Chromosome Disorders
Noninvasive Prenatal Diagnosis: Using Fetal Cells From Maternal Blood
This purpose of this study is to develop noninvasive methods of prenatal diagnosis. Fetal cells can be found in maternal blood. This study is designed to isolate these fetal cells from a sample of the pregnant woman's blood and…
- Trial name
- NCT00064597
- Where
- 5 sites in United States
- Volunteers
- 3,500 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Artery Disease, Peripheral
Simplified and Easy Detection of Arterial Disease in Nursing Homes
Peripheral artery disease (PAD) affects mainly elderly patients. The ankle brachial index (ABI) and ultrasound imaging are the standard diagnostic tools in PAD diagnostic and severity estimation.
- Trial name
- First-SEDAN (NCT03362710)
- Testing
- simplified tools
- Where
- France
- Volunteers
- 225 people
- Sponsor
- University Hospital, Angers
Infertile Men
Reliability for the Detection of Sperm DNA Damage by a Sperm Chromatin Dispersion Test (Halosperm)
It is proposed to measure sperm DNA damage by sperm chromatin dispersion test. This measurement helps to better diagnose male infertility and seems easy to apply in routine.
- Trial name
- NCT02252510
- Testing
- HALOSPERM
- Volunteers
- 40 people
- Sponsor
- University Hospital, Clermont-Ferrand
Detection
Post COVID-19 Syndrome Study With Questionnaires and Instruments Measurements
COVID-19 has caused various long-term symptoms affecting different bodily functions. A study shows that traditional Chinese medicine can balance the human body disorder after a virus infection and restore health.
- Trial name
- NCT05862597
- Testing
- HRV and Pulse diagnosis
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Acute Kidney Injury, Kidney Injury
Automated urIne Flow Detection to Reduce Errors and Nursing Workload
This study is an observational study which seeks to examine a) the accuracy of the Clarity Renal Monitoring System (Clarity RMS)® sensor kit at the bedside compared to manual urine output monitoring, b) total time/effort per…
- Trial name
- AiDe-RN (NCT03636113)
- Testing
- Clarity RMS Electronic Sensor
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Pittsburgh
Nursing Education
An e-Learning Program for Nurses on Evidence-Based Prevention of CKD
Electronic training course to help Syrian nurses prevent chronic kidney disease Why are the investigators doing this study? Chronic kidney disease (CKD) is common in Syria, yet many nurses have not received up-to-date training on…
- Trial name
- NCT07256990
- Testing
- CKD-prevention e-learning course (Your Kidney... our priority)
- Where
- Syria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shandong University
Placenta Previa Complete Centralis
Accuracy of Rail Sign at Detection of PAS
Accuracy OF Rail Sign at Detection Of Placenta Accreta At The second And the Third Trimester Of Pregnancy By Ultrasound Scanning
- Trial name
- NCT07159997
- Testing
- Accuracy of rail sign by ultrasound st diagnosis placent previa
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Sohag University
Colorectal Polyp, Colorectal Adenoma
Evaluation of CAD-EYE/SCALE-EYE for Detection, Classification, and Measurement of Colorectal Polyps: a Prospective Study
The investigators hypothesize that the clinical implementation of an AI system is an optimal tool to monitor, audit and improve the detection and classification of polyps during colonoscopy.
- Trial name
- NCT05236790
- Testing
- Detection and classification and size measurement of polyp by Artificial Intelligence (Cad eye) and the Scale Eye
- Where
- Canada
- Volunteers
- 348 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
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