Clinical trials: Detection
Prostate Adenocarcinoma, PSA Failure
68Ga-PSMA PET/CT in Detecting Prostate Cancer Recurrence in Patients With Elevated PSA After Initial Treatment
The purpose of this research study is to see if recurrent prostate cancer can be identified using a special procedure called a positron emission tomography (PET) scan.
- Conditions
- Prostate Adenocarcinoma, PSA Failure, Recurrent Prostate Carcinoma
- Trial name
- NCT02673151
- Testing
- Computed Tomography (CT) scan, 68Ga-PSMA-11, Positron Emission Tomography (PET)
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Andrei Iagaru
Bone Metastases
Validation of Whole Body PET/CT Foundation Model
Prospective multicenter study to validate the diagnostic performance of whole body PET/CT foundation model for bone lesion detection
- Trial name
- NCT07196995
- Volunteers
- 180 people
- Sponsor
- Shanghai 6th People's Hospital
Healthy
Association Between Heat Pain Detection Threshold and Area of Secondary Hyperalgesia
The purpose of this prospective study is to investigate how close Heat Pain Detection Threshold is associated with the area of secondary hyperalgesia, elicited by the clinical pain model Brief Thermal Sensitization.
- Trial name
- NCT02527395
- Testing
- Brief thermal sensitization, Pain during 1 min. thermal stimulation, Heat pain detection threshold
- Where
- Denmark
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Esophageal Cancer
Non-endoscopic EC Screening Program in Northern Iran
The aim of this study is to assess the effects of implementation of a non-endoscopic esophageal cancer-screening program on outcomes of interest in an asymptomatic high-risk population in Golestan Province, Iran.
- Trial name
- NESP (NCT02311712)
- Testing
- Capsule sponge
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences
Prostate Cancer
Extended Systematic Versus Mri-Assisted pRostate Transperineal Biopsy
This is a randomized controlled trial to evaluate the detection of clinically significant prostate cancer (csPCa) by MRI-targeted approach (MRI-arm) versus 24-core transperineal (TP) systematic biopsy (TP-arm).
- Trial name
- SMART (NCT04685928)
- Testing
- MRI and MRI-guided prostate biopsy, TP-arm Systematic biopsy
- Where
- 8 sites in Hong Kong
- Volunteers
- 403 people
- Sponsor
- Chinese University of Hong Kong
HIV Infections
The Detection of Drug-Resistant HIV-1 in Taiwan
To assess the HIV resistance rate to variable antiretroviral agents in Taiwan, especially in patients with treatment failure, and to know the correlation between the drug resistance pattern and the HIV subtype, we will enroll a…
- Trial name
- NCT00690001
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- National Taiwan University Hospital
Bladder Cancer
Utility of Bladder EpiCheck for Detection of Recurrent Urothelial Carcinoma
Clinical trial to determine the performance characteristics (sensitivity and specificity) of the Bladder EpiCheck test compared to the gold standard cystoscopy and pathology.
- Trial name
- NCT02647112
- Testing
- Bladder EpiCheck
- Where
- 6 sites in Germany, Israel and 2 more
- Volunteers
- 1,050 people
- Sponsor
- Nucleix Ltd.
Pancreatic Cancer
Pancreatic Cancer Early Detection Registry
Identify individuals who are at moderate and high risk or predisposed to developing pancreatic cancer with a familial history in which data collected from this study will be used to identify clinical factors associated with early…
- Trial name
- NCT05519930
- Testing
- hereditary high risk pancreatic cancer
- Where
- United States
- Volunteers
- 326 people
- Sponsor
- Hoag Memorial Hospital Presbyterian
Mammogram Uptake, Breast Cancer
Trial to Evaluate the Impact of Various Pragmatic Interventions to Increase Mammography Uptake Among Defaulted Repeat Screeners in Singapore
Breast cancer is the most common cancer among women in Singapore, accounting for nearly 30% of all female cancers. While regular biennial mammography can reduce mortality, screening rates in Singapore remain low at 34.7%; well…
- Conditions
- Mammogram Uptake, Breast Cancer, Breast Neoplasm, Early Detection of Cancer
- Trial name
- REMIND1 (NCT07651345)
- Testing
- Arm 2: One mailed reminder, Arm 3: Two mailed reminders, Arm 4: Mailed reminder with prescheduled appointment
- Where
- Singapore
- Volunteers
- 12,750 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Emergency Department Visit
Automatic Detection of Eligible Patients to RAUC Protocol (RAUCISABLE)
The augmented rehabilitation of emergency surgeries (ARES, RAUC in French) is a research program supported by Amiens-Picardy University Hospital and the University of Picardy Jules Verne.
- Trial name
- RAUCISABLE (NCT07037719)
- Where
- France
- Volunteers
- 300,000 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Cancer
Screening of Cancer Through Novel Female Specific Biomarkers
Can reliable biomarkers be identified for detection of cancer at early stages using menstrual blood (MB)? Preliminary mass spectrometry (MS) results suggest that MB provides biomarkers for identification of disease such as…
- Trial name
- NCT03951428
- Testing
- Menstrual Blood Screening Test
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- LifeStory Health Inc.
Ultrasonography
Ultrasonography of Optic Nerve Sheath Diameter for Noninvasive Detection of Raised Intracranial Pressure: ORIENT Study
This study aims to adopt a multi-center large sample size study to define (1) the normal range of Chinese ONSD; (2) ONSD diagnosis for patients with high intracranial pressure; (3) to analyze the correlation between ONSD and…
- Trial name
- NCT04981548
- Testing
- no intervention
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- The First Hospital of Jilin University
Tuberculosis
Development of a Rapid and Accurate Diagnostic Assay for Tuberculosis
This study evaluates new technique for diagnosis of tuberculosis. Among patients who are suspected with tuberculosis, participants will be tested conventional method including Xpert TB/RIF assay, and new diagnostic technique…
- Trial name
- NCT03423550
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Asan Medical Center
Medical Oncology, Cancer
Ezra Faster Scan Study
The Ezra Faster Scan study uses non-invasive magnetic resonance imaging (MRI) technology that can "visually" detect early and late-stage cancer, and other pathologies.
- Conditions
- Medical Oncology, Cancer, Healthy
- Trial name
- FasterScan (NCT05385718)
- Testing
- Magnetic Resonance Imaging
- Where
- 5 sites in United States
- Volunteers
- 694 people, healthy volunteers welcome
- Sponsor
- Ezra AI, Inc.
Colorectal Cancer, Colorectal Neoplasms
Evaluation of a Model for the Early Diagnosis of Colorectal Cancer by the Detection of 5-hydroxymethylcytosine (5-hmC) in Plasma Cell-free DNA to the Community Colorectal Cancer Screening Program
The incidence rate and mortality of colorectal cancer are increasing year by year. Most colorectal cancer develops from colorectal adenoma and is a disease that can be prevented and controlled.
- Trial name
- METHOD-3 (NCT05638243)
- Where
- China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Fudan University
Diabetes Free Completely Edentulous Patients
Detection of Pressure Areas for Two Elastomeric Impressions
Forty completely edentulous patients were selected and randomly distributed into two groups 20 patients each.Group I received complete dentures constructed from elastomeric impression with wax spacer,group II received complete…
- Trial name
- NCT03226990
- Testing
- impression technique
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Hematologic Cancer, CRS - Cytokine Release Syndrome
Early Detection of Complications During Immunotherapy for Haematological Malignancy
Aims To identify patients that should remain admitted in hospital for more intense surveillance because of high risk for development of clinical complications Expand the understanding of the interactions between physiology and…
- Trial name
- NCT06377059
- Testing
- WARD
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Gastrointestinal Lesions
Photon-Counting CT for Detection of Small Gastrointestinal Lesions
This comparative matched-cohort study aims to evaluate the diagnostic performance of contrast-enhanced photon-counting computed tomography (PCCT) for detecting small gastrointestinal lesions compared with energy-integrating…
- Trial name
- PCCT-GI (NCT07748923)
- Testing
- Contrast-Enhanced Photon-Counting Computed Tomography, Contrast-Enhanced Energy-Integrating Detector Dual-Energy Computed Tomography
- Where
- China
- Volunteers
- 1,762 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Colorectal Cancer
Exploratory Study of the Relevance of a Blood Test in the Management of Patients in the Context of Colorectal Cancer Screening
Colorectal cancer (CRC) is the third most common cancer in men and the second in women with an incidence of 43,350 new cases in 2018. This incidence is increasing every year. Early detection is crucial in this pathology.
- Trial name
- PREDICT-IRFC (NCT04767568)
- Testing
- Blood sample, Tumor tissue, stool collection
- Where
- 3 sites in France
- Volunteers
- 400 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
HIV, Quality of Life
Validation of a Multidimensional Scale for the Detection of Health Needs in People With HIV
The primary objective is to evaluate the diagnostic performance of the multidimensional screening test in identifying alterations in the domains considered in people with HIV, in order to improve the predictivity of disorders…
- Trial name
- MUSA (NCT07077642)
- Where
- 11 sites in Italy
- Volunteers
- 200 people
- Sponsor
- Giovanni Di Perri
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