Clinical trials: Development; Delayed, Mental
Genetic Disease, Neurologic Disorder
Use of Long Read Genome Sequencing in Patients Suffering From Neurodevelopmental Troubles
Patients with neurodevelopmental diseases and their families need to identify the genetic cause of the disease to allow for recognition of the disability, genetic counseling, and possible hope for participation in therapeutic…
- Conditions
- Genetic Disease, Neurologic Disorder, Developmental Delay Disorder, Growth Disorders
- Trial name
- HiFi-NDD (NCT05643274)
- Where
- 5 sites in France
- Volunteers
- 10 people
- Sponsor
- Nantes University Hospital
Child Development, Child Development Disorder
The Indonesian Version of Ages and Stages Questionnaire III Accuracy Compared to Bayley Scales of Infant Development III
This study aimed to evaluate the concurrent validity information of the 24-, 30-, and 36-month Indonesian ASQ-3 with the Bayley Scales of Infant and Toddler Development 3rd Edition (BSID-III) in Indonesian children.
- Conditions
- Child Development, Child Development Disorder, Development Delay, Developmental Delay
- Trial name
- NCT05408351
- Where
- Indonesia
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Developmental Delay
Head Start Family Navigator Intervention
Headstart (HS) is an early childhood education program for low-income children. Preliminary analyses of Hamilton County HS preschoolers with developmental concerns identified 26% with "severe concern" necessitating developmental…
- Trial name
- HeadStartNav (NCT03499405)
- Testing
- Family Navigator Intervention
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
CLIFAHDD, Congenital Contractures of the Limbs and Face, Hypotonia, and Developmental Delay
Aprepitant for the Treatment of CLIFAHDD
There are no drug treatments for individuals with Congenital Contractures of the Limb and Face, Hypotonia, and Developmental Delay (CLIFAHDD), an ultra-rare and severe neurodevelopmental disease.
- Conditions
- CLIFAHDD, Congenital Contractures of the Limbs and Face, Hypotonia, and Developmental Delay, NALCN Channelopathy, Ataxia - Other
- Trial name
- NCT07845825
- Testing
- Aprepitant Powder for Oral Suspension
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Developmental Delay
Effects of Rainbow Parachute Games on UE Strength and Social-Emotional Skills in Children With Developmental Delay
Conducted as a randomized trial, this study examines the impact of rainbow parachute games on upper extremity strength and social-emotional skills in children (ages 5-8) with developmental delays.
- Trial name
- NCT07756931
- Testing
- Rainbow parachute Games, Rhyming Activities
- Where
- Pakistan
- Volunteers
- 12 people
- Sponsor
- Riphah International University
Attention Deficit Hyperactivity Disorder
Effects of Attention Training on Children
Using a double-blind, randomized controlled design to investigate the therapeutic effects of interactive attention training for children with Attention Deficit Hyperactivity Disorder who are receiving conventional rehabilitation…
- Trial name
- NCT04375059
- Testing
- using interactive attention training system
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Speech and Language Disorder, Speech Therapy
Providing Speech Therapy Awareness in Private Schools
There has been limited research in the area of speech and language therapy awareness in Pakistan. The study aims to assess the efficacy of providing speech therapy awareness in private schools through a pre-post model.
- Conditions
- Speech and Language Disorder, Speech Therapy, Speech Delay, Swallowing Disorder
- Trial name
- NCT04505696
- Testing
- Speech-Language Pathology Presentation
- Where
- Pakistan
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Autism Spectrum Disorder, Developmental Delay
Can Novel Telemedicine Tools Reduce Disparities Related to Early Identification of Autism
In this study, the investigators are trying to find new ways to screen for autism spectrum disorder (ASD) in young children. The investigators want to see if people like pediatricians can screen children for ASD while a…
- Trial name
- NCT03847337
- Testing
- Telehealth-Screening Tool for Autism in Toddlers (STAT), Telehealth-Autism Spectrum Disorder-Pediatrics (ASD-PEDS)
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Vanderbilt University Medical Center
Developmental Delay
Effects of Power Ball on Proximal Muscle and Refractive Errors in Developmental Delay.
When a child does not meet developmental milestones at the anticipated times, it is referred to as having a developmental delay. These benchmarks cover social, emotional, cognitive, physical, and communication abilities.
- Trial name
- NCT06461572
- Testing
- conventional therapy, conventional therapy along with standard therapy and stability exercises.
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Microcephaly, Hyperkinesis With Developmental Delay
Intensive Therapy for Children With Microcephaly, Hyperkinetic Movements, or Global Developmental Delay
This trial will consist of a clinical series of up to 50 children with Global Developmental Delay and concomitant microcephaly or hyperkinetic movements.
- Conditions
- Microcephaly, Hyperkinesis With Developmental Delay, Global Developmental Delay
- Trial name
- NCT04816175
- Testing
- Acquire Therapy
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Virginia Polytechnic Institute and State University
Epilepsy; Seizure, Neuromuscular Diseases
North Carolina Genomic Evaluation by Next-generation Exome Sequencing, 2
The "North Carolina Clinical Genomic Evaluation by Next-gen Exome Sequencing, 2 (NCGENES 2)" study is part of a larger consortium project investigating the clinical utility, or net benefit of an intervention on patient and family…
- Conditions
- Epilepsy; Seizure, Neuromuscular Diseases, Brain Malformation, Intellectual Disability
- Trial name
- NCGENES2 (NCT03548779)
- Testing
- Pre-visit prep, usual care + exome seq
- Where
- 3 sites in United States
- Volunteers
- 548 people
- Sponsor
- University of North Carolina, Chapel Hill
Developmental Delay Disorder, Repetitive Transcranial Magnetic Stimulation (rTMS)
Repetitive Transcranial Magnetic Stimulation Combined With Language Training for Language Disorders in Children With Global Developmental Delay
This study explores a safe and effective new approach to improve language function in children with Global Developmental Delay (GDD).
- Conditions
- Developmental Delay Disorder, Repetitive Transcranial Magnetic Stimulation (rTMS), Global Developmental Delay, Language Disorders in Children
- Trial name
- NCT07369960
- Testing
- Transcranial magnetic stimulation, individualized language training
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Xiangya Hospital of Central South University
Urologic Diseases, Gastrointestinal Diseases
PACT Programme for Parents of Children With SHCN
This randomised controlled trial aims to determine the efficacy of a 12-week, smartphone-based Prosocial-orientated Acceptance and Commitment Training (PACT) programme plus age-appropriate positive parenting advice on the…
- Conditions
- Urologic Diseases, Gastrointestinal Diseases, Vascular Diseases, Cleft Lip and Palate
- Trial name
- NCT05467527
- Testing
- Prosocial-orientated Acceptance and Commitment Training plus positive parenting advice, Positive parenting advice
- Where
- 2 sites in Hong Kong
- Volunteers
- 196 people
- Sponsor
- Chinese University of Hong Kong
Developmental Delay
Responsiveness of the Object Permanence Scale
The aim of the study is the examining responsiveness of the Object Permanence Scale. The sample of the study will be 7-16 months old babies with motor developmental delay.
- Trial name
- NCT05749783
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people
- Sponsor
- Tokat Gaziosmanpasa University
Autism, Developmental Delay Disorders
Project EARLY: Engagement, Assessment, Referral, & Linkage for Young Children
Emerging evidence demonstrates that Autism Spectrum Disorder (ASD) can be reliably diagnosed by age two, and that early identification and intervention can improve outcomes.
- Trial name
- NCT02359084
- Testing
- Family Navigation, Conventional Care Management
- Where
- 10 sites in United States
- Volunteers
- 340 people
- Sponsor
- Boston University
Nutritional Deficiencies, Developmental Delay
Project Grow Smart: Intervention Trial of Multiple Micronutrients and Early Learning Among Infants in India
Project Grow Smart evaluates the impact fortification with multiple micronutrient powders (MNP) vs. placebo (one vitamin) on child development (primary outcome) and on micronutrient status, growth, and morbidity (secondary…
- Trial name
- GrowSmart (NCT01660958)
- Testing
- MNP, Early Learning
- Where
- India
- Volunteers
- 834 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Global Developmental Delay
Umbilical Cord Blood Therapy for Global Developmental Delay
This open-label study aims to evaluate the safety and efficacy of autologous or allogeneic umbilical cord blood therapy for children with global developmental delay.
- Trial name
- NCT01769716
- Testing
- Umbilical cord blood transplantation
- Where
- South Korea
- Volunteers
- 14 people
- Sponsor
- MinYoung Kim, M.D.
Motor Delay
Effects of Conventional Physical Therapy With and Without Cuevas Medek Exercises in Developmental Delay
There are several etiologies for developmental delay (DD). One of the main causes of developmental delay is cerebral palsy (CP), which has a variety of clinical characteristics brought on by damage to the developing brain.
- Trial name
- NCT06522451
- Testing
- conventional physical therapy, Conventional physical therapy along with cuevas medek exercises
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Riphah International University
Autism Spectrum Disorder, Moderate Language Delay
Direct Instruction Language for Learning in Autism Spectrum Disorder
The purpose of this study is to test whether Direct Instruction - Language for Learning (DI-LL) is an effective way to teach language skills to children with autism spectrum disorder (ASD) and moderate language delay.
- Trial name
- DILLASD (NCT02483910)
- Testing
- Direct Instruction-Language for Learning (DI-LL) via telehealth (e.g., Zoom or WebEx), Standard of care delivered via telehealth (e.g., Zoom or WebEx)
- Where
- United States
- Volunteers
- 137 people
- Sponsor
- Emory University
Developmental Delay
Mirror Neuron Network Dysfunction as an Early Biomarker of Neurodevelopmental Disorder
Background: People show changes in brain activity when they watch other people do actions. This may be part of early social and communication skills.
- Trial name
- NCT03307317
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)