Clinical trials: Development, open to volunteers
Autism Spectrum Disorder
Effects of Muscle Energy Technique With and Without Stationary Cycling on Toe Walking With ASD
In Autism spectrum disorder (ASD) is a developmental disability caused by differences in the brain. People with ASD often have problems with social communication and interaction, and restricted or repetitive behaviors or…
- Trial name
- NCT06673732
- Testing
- Muscle Energy Technique with Stationary Bi-Cyclying, Muscle Energy Technique without Stationary Cycling
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University
Endometriosis
" Development of Primary Cultures of Diaphragmatic Myoblasts for Basic Research Purposes "
Neuromuscular diseases (NMDs) affecting motor neurons (MN) induce progressive muscle denervation, and become fatal when respiratory muscles e.g. the diaphragm are affected and can no longer contract.
- Trial name
- MYODiaph (NCT07380308)
- Testing
- During the surgery planned as part of the routine care of the patient, a part of the tissue sample will be saved in order to carry out the analysis planned for the research.
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Mitochondrial Disease
Development of a New Technique for Quantifying Mitochondrial DNA in Single Muscle Fibers
Mitochondrial diseases (MDs) are the most common metabolic disorders. Due to their great clinical and genetic heterogeneity, their diagnosis relies exclusively on the identification of pathogenic variants in nuclear genes or in…
- Trial name
- DIGITAL_MITO (NCT07511608)
- Testing
- Quantification of Mitochondrial DNA Heteroplasmy and Copy Number by Digital PCR in Mitochondrial Diseases
- Where
- 3 sites in France
- Volunteers
- 4 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Post-traumatic Stress Disorder (PTSD)
PTSD Risk Prediction Model for EICU Survivors
Brief Title: PTSD Risk Prediction Model for EICU Survivors Official Title: Development and Validation of a Risk Prediction Model for Post-Discharge Post-Traumatic Stress Disorder in Emergency Department-Admitted EICU Survivors…
- Trial name
- NCT07747415
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Sir Run Run Shaw Hospital
Vestibular Dysfunction, Dizziness
Vestibular Balance-Cognition Dual-Task Digital System: Development of a Smart Rehabilitation Platform for the Elderly and Prediction of Balance Function Risks
This study is being done to better understand how vestibular problems and thinking abilities (such as attention and mental flexibility) are related in older adults, and how doing a balance task and a thinking task at the same…
- Conditions
- Vestibular Dysfunction, Dizziness, Falls (Accidents) in Old Age, Balance Assessment
- Trial name
- NCT07735078
- Testing
- Instrumented balance and gait assessment using wearable inertial sensors, Questionnaires and paper-based cognitive tests
- Where
- Taiwan
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Axial Length, Myopia
China Children Eye Study
The primary objective of this multi-center, observational study is to establish the reference ranges of axial length in Chinese children and adolescents.
- Conditions
- Axial Length, Myopia, Child Development
- Trial name
- CCES (NCT05770661)
- Where
- 2 sites in China
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Diaphragm Issues, Mechanical Ventilation Complication
Diaphragm Atrophy and Dysfunction in Mechanical Ventilation
The gold standard of twitch transdiaphragmatic pressure recordings would ultimately clear the fog around the rate of development of Ventilator induced Diaphragm Dysfunction (VIDD) in mechanically ventilated patients over time.
- Conditions
- Diaphragm Issues, Mechanical Ventilation Complication, Respiratory Failure, Intensive Care (ICU) Myopathy
- Trial name
- DAM (NCT05211661)
- Testing
- Respiratory Muscle Testing
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- RWTH Aachen University
Developmental Language Disorder, Speech Sound Disorder
A Developmental Framework For Linking Phonological And Morpho-syntactic Sequential Pattern Rules In DLD: Production
The broad aim of this clinical study is to assess the hypothesis that morphological and phonological deficits are linked by a broader deficit in sequential pattern learning.
- Conditions
- Developmental Language Disorder, Speech Sound Disorder, Specific Language Impairment
- Trial name
- NCT04558541
- Testing
- Sensitivity to phonological rules, Sensitivity to semantic category cues.
- Where
- 2 sites in United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Father Flanagan's Boys' Home
Metastatic Head and Neck Squamous Cell Carcinoma, Recurrent Head and Neck Squamous Cell Carcinoma
FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC
Ficerafusp alfa is directed against two targets, Epidermal Growth Factor Receptor (EGFR) and Transforming Growth Factor beta (TGF-β).
- Trial name
- FORTIFI-HN01 (NCT06788990)
- Testing
- Ficerafusp alfa, Pembrolizumab (KEYTRUDA®)
- Where
- 231 sites in United States, Argentina and 26 more
- Volunteers
- 650 people
- Sponsor
- Bicara Therapeutics
Autism, Pervasive Developmental Disorder
The Impact of a Virtual Magic Trick Training Program
The proposed project will attempt to confirm the benefits of a structured magic trick training program (MTTP) experience in adolescents with autism.
- Trial name
- NCT05664841
- Testing
- magic trick training
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Alabama at Birmingham
Cleft Palate Children
Effect of Infant Sign Training on Speech-language Development
Children born with a cleft lip and palate (CLP) are known to be at risk for speech-language disorders that impact academic and social emotional growth.
- Trial name
- NCT06143254
- Testing
- Infant sign training, Verbal training
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- University Hospital, Ghent
Autism Spectrum Disorder
Social Skills Training Group Effectiveness in Adolescents With Autism Spectrum Disorder
Autism spectrum disorders (ASD) is a neurodevelopmental disorder characterized by persistent deficits in social communication and social interaction across multiple contexts, and the presence of restricted, repetitive behavior…
- Trial name
- NCT05857813
- Testing
- Program for the Education and Enrichment of Relational Skills (PEERS®)
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Nutrition Poor, Nutritional Deficiency
Development and Testing of Nutritional Algorithms (NACHO)
The goal of this research study is to develop a nutrition algorithm to optimize nutritional status and improve quality of life during for participants who are completing or have completed cancer treatment.
- Conditions
- Nutrition Poor, Nutritional Deficiency, Quality of Life
- Trial name
- NCT05825469
- Testing
- Nutrition Algorithm
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Dana-Farber Cancer Institute
OVARIAN STIMULATION
Follicular Volume at the Time of Final Oocyte Maturation in Poor Responders, and Its Correlation With Oocyte Maturity
Women with a severely diminished ovarian reserve and monofollicular growth are at a higher risk of premature ovulation as well as poor quality oocytes.
- Trial name
- NCT06839274
- Testing
- transvaginal Ultrasound
- Where
- United Arab Emirates
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Body Temperature Monitoring
Moni-Patch Temperature Data Collection for Algorithm Development During Surgery
This study aims to collect synchronized temperature measurements from the Moni-Patch Temperature Monitoring Patch System and an esophageal temperature probe during surgery to support the development and refinement of the…
- Trial name
- NCT07901296
- Testing
- Moni-Patch Temperature Monitoring Patch System
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Murata Vios, Inc.
Stuttering
Development and Pilot Testing of Virtually Simulated Intervention for Patients Having Stuttering
This study aims to develop and pilot test a culturally appropriate virtual reality (VR)-based speech restructuring intervention for individuals with stuttering in Pakistan.
- Trial name
- NCT07833969
- Testing
- Virtually Simulated Intervention
- Where
- Pakistan
- Volunteers
- 10 people
- Sponsor
- Riphah International University
Congenital Adrenal Hyperplasia
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Crinecerfont in Participants With Classic Congenital Adrenal Hyperplasia (CAH) Who Are Less Than 4 Years Old
The main objective of this study is to assess the safety and tolerability of crinecerfont in pediatric participants 3 months to <4 years of age with CAH.
- Trial name
- NCT07536269
- Testing
- Crinecerfont
- Where
- 11 sites in United States
- Volunteers
- 20 people
- Sponsor
- Neurocrine Switzerland GmbH
Autism
To Share or Not To Share: Navigating Disclosure and Stigma Among Family Caregivers of Autistic Young Adults_Group Intervention
This study is a caregiver support program for family caregivers of autistic young adults (ages 18 to 26) as their family members navigate young adulthood.
- Trial name
- NCT07856927
- Testing
- Group Intervention
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Wisconsin, Madison
5 Year Old Children Born Prematurely
Early Detection of Developmental Abnormalities of Preterm Infants at 5 Years of Age
The project is a national, prospective, multicenter, interventional pilot project focused on the follow up of 5 year old children that were born prematurely.
- Trial name
- NCT07391527
- Testing
- Pediatric check-up
- Where
- 4 sites in Czechia
- Volunteers
- 210 people
- Sponsor
- Institute of Health Information and Statistics of the Czech Republic
Klinefelter Syndrome, Trisomy X
The eXtroardinarY Babies Study: Natural History of Health and Neurodevelopment in Infants and Young Children With Sex Chromosome Trisomy
This study is designed to research the natural history of neurodevelopment, health and early hormonal function in infants with XXY/Klinefelter syndrome, XYY, XXX and other sex chromosome variations in an effort to identify early…
- Conditions
- Klinefelter Syndrome, Trisomy X, XYY Syndrome, XXXY and XXXXY Syndrome
- Trial name
- NCT03396562
- Testing
- Assessments of Development and Growth
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of Colorado, Denver
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