Clinical trials: Development Disorder, Child
Child Developmental Delay, Child Malnutrition
Maternal B12 Supplementation to Improve Infant B12 Deficiency and Neurodevelopment
Vitamin B12 plays a key role in the development and normal functioning of the brain and nervous system. Unborn and new-born infants derive their vitamin B12 stores almost entirely from maternal B12 stores.
- Conditions
- Child Developmental Delay, Child Malnutrition, Maternal Exposure, Vitamin B 12 Deficiency
- Trial name
- MATCOBIND (NCT03783104)
- Testing
- B12 Supplement
- Where
- 2 sites in India, Nepal
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- University College, London
Autistic Disorder
Using a Voice Output Communication Aid to Facilitate Language Development in Young Children With ASD
It was proposed that in order to teach these children to use a Voice Output Communication Aid (VOCA), it should be introduced through a play-based situation using parents as the primary interventionist.
- Trial name
- NCT01816178
- Testing
- communication training
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of South Alabama
Autism, Autism Spectrum Disorder
Static Balance in Children With Autism vs. Neurotypical Peers
The Virtual Reality Rehabilitation System (VRRS) is an innovative and sophisticated technology, aimed to generate immersive and interactive settings intended for therapeutic and evaluative objectives.
- Trial name
- NCT06152510
- Testing
- Virtual Reality Rehabilitation System
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Arrest of Bone Development or Growth, Constitutional Delay of Growth and Puberty
YoUng Adolescents' behaViour, musculoskeletAl heAlth, Growth & Nutrition
More children will survive to adulthood today than at any other point in human history, as evidenced by the proportion of live births and absolute numbers.
- Conditions
- Arrest of Bone Development or Growth, Constitutional Delay of Growth and Puberty, Malnutrition, Child, Gestational Diabetes
- Trial name
- YUVAAN (NCT05603793)
- Testing
- Knowledge, Attitude & Practices
- Where
- India
- Volunteers
- 1,304 people, healthy volunteers welcome
- Sponsor
- Hirabai Cowasji Jehangir Medical Research Institute
Autism Spectrum Disorder (ASD), Neurodevelopmental Disorders
Arabic NODA Validation Study for Autism Diagnosis in Saudi Arabia
This study aims to validate the Arabic adaptation of the Naturalistic Observation Diagnostic Assessment (NODA), a telehealth tool designed to help diagnose Autism Spectrum Disorder (ASD) in young children.
- Conditions
- Autism Spectrum Disorder (ASD), Neurodevelopmental Disorders, Child Development Disorders, Pervasive
- Trial name
- NODA-ARSA (NCT07089108)
- Testing
- Arabic NODA Video-Based Diagnostic Assessment
- Where
- Saudi Arabia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Prince Sultan Military Medical City
Developmental Language Disorder
Contextual Word Learning in Children With Developmental Language Disorder
Many children have developmental language disorder, which makes it difficulty to learn language, including vocabulary, and results in ongoing academic and social difficulties.
- Trial name
- NCT05988190
- Testing
- Contextual Word Learning Intervention
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Binghamton University
Language Disorders in Children
Let's Know!2: Language-focused Intervention for Children at Risk of Comprehension Difficulties
In the proposed project, the investigators will conduct a multisite randomized controlled trial (RCT) to determine the efficacy of Let's Know!2, a small-group, language focused comprehension intervention, on children's lower- and…
- Trial name
- LK!2 (NCT05133479)
- Testing
- Let's Know! small-group or TierL 2 Intervention
- Where
- 2 sites in United States
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- MGH Institute of Health Professions
Randomized Controlled Trial for Speech Disorders in Children
Treatment Efficacy for Developmental Motor Speech Disorders
The purpose of this study is to carry out a high-level treatment efficacy study on children with speech sound disorders with motor speech involvement (SSD-MSI) using a well-controlled Randomized Controlled Trial design.
- Trial name
- NCT02105402
- Testing
- PROMPT
- Where
- 3 sites in Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- The Prompt Institute
Health Problems in Pregnancy, Pregnancy Outcomes
Peking University Birth Cohort in Tongzhou
The PKUBC-T is a prospective cohort study carried out in Tongzhou district of Beijing, China. The primary aim of this study is to investigate the short-term and long-term effects of pre-pregnant and prenatal exposure on maternal…
- Conditions
- Health Problems in Pregnancy, Pregnancy Outcomes, Gestational Diabetes, Gestational Hypertension
- Trial name
- PKUBC-T (NCT03814395)
- Testing
- No intervention
- Where
- China
- Volunteers
- 5,426 people, healthy volunteers welcome
- Sponsor
- Peking University
Autism Spectrum Disorder, Autism
Mitochondrial Dysfunction in Autism Spectrum Disorder
Researchers at Arkansas Children's Hospital Research Institute are conducting a study about mitochondrial function in children. The study involves up to 5 visits to Arkansas Children's Hospital with fasting blood draws…
- Conditions
- Autism Spectrum Disorder, Autism, Mitochondrial Disease, Developmental Delay
- Trial name
- Mito (NCT02000284)
- Where
- United States
- Volunteers
- 297 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Development, Child, Postnatal Depression
Early Detection Neurodevelopmental Disorders of Children and Prevention of Postnatal Depression by Mobile Health App
The goal of this observational study is to confirm the impact of using this app adapted to be more specific for screening for 5 neurodevelopmental disorders and to evaluate the mothers' support program on the incidence of…
- Trial name
- NCT06301087
- Testing
- Web Application
- Where
- France
- Volunteers
- 55,618 people, healthy volunteers welcome
- Sponsor
- Weprom
Molar Incisor Hypomineralisation
Local Anesthesia With Lidocaine or Articaine for Molars Affected by MIH
Aims: Comparison of injection pain with lidocaine and articaine in children with MIH . Comparison of the efficacy of lidocaine and articaine during treatment of MIH molars.
- Trial name
- NCT05200884
- Testing
- Lidocaine 2%, Articaine 4%
- Where
- Syria
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Latakia University
Autistic Disorder
A Trial to Assess the Efficacy and Safety of Medical Grade Cannabis in Children Diagnosed With Autism Spectrum Disorder
This single center, double-blinded, randomized, placebo-controlled crossover trial will assess the efficacy and safety of extraction of cannabis flowers dissolved in olive oil (30% CBD and 1.5% Δ9-THC) vs.
- Trial name
- NCT05413187
- Testing
- Medical Grade Cannabis oil
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- TO Pharmaceuticals
Attention Deficit and Disruptive Behavior Disorders, Child Behavior Disorders
Study of Children at Risk for Disruptive Behavior Disorders
A conduct disorder is characterized by repetitive and persistent patterns of behavior where the basic rights of others and rules are violated.
- Conditions
- Attention Deficit and Disruptive Behavior Disorders, Child Behavior Disorders, Passive-Aggressive Personality Disorder
- Trial name
- NCT00001233
- Where
- United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Gonad Regulating Hormone Adverse Reaction, Analgesic Adverse Reaction
Neurobehavioral Development in Toddlers and Preschoolers in Relation to Prenatal Exposure of Mild Analgesics (NeuroToP - a COPANA Follow up)
Fundamental aspects of both neurological and reproductive function are established in fetal life, and there is a present increased awareness of the potential effects of fetal exposures on neurodevelopmental and reproductive…
- Conditions
- Gonad Regulating Hormone Adverse Reaction, Analgesic Adverse Reaction, Developmental Disability, Adhd
- Trial name
- NeuroToP (NCT07316387)
- Where
- Denmark
- Volunteers
- 685 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Pollution; Exposure, Neurodevelopmental Disorders
Air Pollution and Development in the Boricua Youth Study
This study seeks to understand the relationship between prenatal maternal air pollution exposure and offspring risk for ADHD and examine two potential -modifiable- mechanisms: prenatal maternal inflammation and offspring sleep…
- Trial name
- NCT05368493
- Testing
- MRI task
- Where
- 2 sites in United States, Puerto Rico
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Molar Incisor Hypomineralization, Anesthesia, Local
Effect of Silver Diamine Fluoride on Local Anesthesia in Hypomineralized Molars
The purpose of this randomized, controlled clinical study is to evaluate if application of 38% SDF increases the efficacy of local anesthesia during operative dentistry on permanent molars affected by molar-incisor hypoplasia…
- Trial name
- NCT05964387
- Testing
- SDF
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Autism Spectrum Disorder
Preliminary Efficacy of Occupational Therapy Integrating Horses on Self-regulation in Youth With Autism
The goal of this clinical trial is to learn about occupational therapy integrating horses for autistic youth. The main questions it aims to answer are: Does occupational therapy integrating horses improve self-regulation in…
- Trial name
- NCT05846932
- Testing
- OTEE HORS, OT Clinic
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Preterm Birth, Neurodevelopmental Disorders
Guangzhou Preterm and Term Birth Cohort Study
The Guangzhou Preterm-Term Birth Cohort (GPTBC) is a prospective observational study of how early-life nutrition, environmental exposures, and family factors relate to the health and development of preterm and term infants and…
- Conditions
- Preterm Birth, Neurodevelopmental Disorders, Overweight, Obesity
- Trial name
- GPTBC (NCT07756177)
- Testing
- No Intervention: Observational Cohort
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
HIV Infections
Natural History Study of HIV Acquired in Infancy or Childhood
Background: About 10,000 children in the United States have been living with HIV infection since birth. Little is known about the long-term effects of HIV infection and its treatment on the growth and development of these…
- Trial name
- NCT00924365
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)