Clinical trials: Development Disorders
Schizophrenia, Psychosis
Social Cognitive Training for Psychosis: Treatment Development
The primary aim of this proposal is to develop, refine, manualize and assess the feasibility and preliminary efficacy of a brief, narrowly-focused social cognitive intervention for individuals with psychosis.
- Trial name
- NCT01579422
- Testing
- social cognitive training
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Yale University
Premature Infant
Premature Infants' Developmental Function, Daily Living, Participation, and Quality of Life: A Longitudinal Study
This study tracks the long-term development of premature infants to examine how birth profiles, risk factors, and physical functioning influence their activities, participation, and quality of life.
- Trial name
- NCT07100353
- Where
- Taiwan
- Volunteers
- 450 people
- Sponsor
- Chang Gung Memorial Hospital
Preterm Infant, Exposure to Radiofrequency
Impact of Chronic Exposure to Radiofrequency Electromagnetic Fields on Neurophysiological Development in the Preterm Neonate
The massive use of highly technological devices in Neonatal Intensive Care Units may expose preterm neonates to electromagnetic fields, especially radiofrequencies, at low doses but continuously and chronically.
- Trial name
- NeuroPrem-RF (NCT03928457)
- Testing
- Parental questionnaire, Daily continuous recording of radiofrequency exposure levels, Follow-up of daily infants environmental and clinical parameters
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Polycystic Ovary Syndrome
The Effect of Therapy Combination in PCOS With Dlbs 3233
The effect of combination therapy dlbs 3233 and clomifen citrate vs clomifen citrate on homa ir, maturation follicle, and menstrual cycle in PCOS cases at Muhammadiyah Asri Medical Center Hospital
- Trial name
- NCT07403201
- Testing
- dlbs 3233 , clomifen citrat
- Where
- Indonesia
- Volunteers
- 90 people
- Sponsor
- Inlacinpenelitian
Effect of Breastfeeding on Maternal and Child Health Outcomes
Promotion of Breastfeeding Intervention Trial
The overall goal of the PROBIT study is to investigate the influence of a randomized breastfeeding promotion intervention designed to increase the duration and exclusivity of breastfeeding ("the breastfeeding promotion…
- Trial name
- PROBIT (NCT01561612)
- Testing
- Breastfeeding promotion and support
- Where
- Belarus
- Volunteers
- 17,046 people
- Sponsor
- Harvard Pilgrim Health Care
Autism Spectrum Disorder (ASD), Autism
Judo Training for People With Autism Spectrum Disorder, Physical Fitness and Psychological Indicators
Physical fitness and psychological indicators are key factors in healthy development. Individuals with autism spectrum disorder (ASD) tend to have lower levels of physical fitness and mental health than their neurotypical peers.
- Trial name
- JUDOASD/PA/PSY (NCT07419919)
- Testing
- Judo training for people with ASD - training in integration groups with non-ASD people
- Where
- Poland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Infertility, In Vitro Maturation of Oocytes
Aspire In Vitro Maturation Study
A study to assess the Capacitation - in-vitro maturation (CAPA-IVM) system as an option for patients with a good ovarian reserve to achieve pregnancy.
- Conditions
- Infertility, In Vitro Maturation of Oocytes, Assisted Reproduction Technologies
- Trial name
- AIM (NCT07789730)
- Testing
- CAPA-IVM
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Inception Fertility Research Institute, LLC
Osteogenesis Imperfecta
Study to Evaluate Efficacy and Safety of Romosozumab Compared With Bisphosphonates in Children and Adolescents With Osteogenesis Imperfecta
The primary objective of this study is to evaluate the effect of romosozumab treatment for 12-months compared with bisphosphonate(s) on the number of clinical fractures at 12-months; the number of any fractures at 12-months and…
- Trial name
- NCT05972551
- Testing
- Romosozumab, Bisphosphonate
- Where
- 65 sites in United States, Australia and 16 more
- Volunteers
- 111 people
- Sponsor
- Amgen
Growth Hormone Deficiency
Safety and Efficacy of SR-hGH (Sustained-release Human Growth Hormone, Declage Inj.)
As studies demonstrate, the administration of recombinant human GH (rhGH) in adults with GH deficiency has been known to improve metabolic impairment and quality of life.
- Trial name
- NCT01605331
- Testing
- sustained-release recombinant human GH (SR-rhGH)
- Volunteers
- 132 people
- Sponsor
- LG Life Sciences
Antimicrobial Resistance
Algorithm Using a Rapid Diagnostic Test for the Management of Childhood Febrile Diseases.
In Sub-Saharan Africa (SSA), fever remains a major public health problem in children. The introduction of malaria rapid diagnostic tests (RDTs) in routine healthcare has greatly improved the management of malaria.
- Trial name
- e-MANIC (NCT05285657)
- Testing
- Two-step malaria RDT detecting PfHRP2/pLDH (SD Ag Bioline Malaria Ag P.f/Pan: Standard Diagnostics, Hagal-Dong, Korea)
- Where
- 2 sites in Burkina Faso
- Volunteers
- 1,176 people
- Sponsor
- Institut de Recherche en Sciences de la Sante, Burkina Faso
Comorbid Insomnia and Sleep Apnea, Insomnia
Wearable Voice-Guided BBTi for Comorbid Insomnia and Sleep Apnea (COMISA)
This study investigates the efficacy of a wearable voice-guided Brief Behavioral Therapy for Insomnia (BBTi) combined with a smart eye-mask device for individuals with Comorbid Insomnia and Sleep Apnea (COMISA).
- Conditions
- Comorbid Insomnia and Sleep Apnea, Insomnia, Obstructive Sleep Apnea
- Trial name
- BBTi-COMISA (NCT07521319)
- Testing
- Brief Behavioral Therapy for Insomnia (BBTi), Smart Eye-Mask with Voice-Guided Modules
- Where
- Taiwan
- Volunteers
- 361 people
- Sponsor
- National Sun Yat-sen University
Osteogenesis Imperfecta (OI)
A Dose REgimen-Finding Study of AGA2115 in Chinese Patients With Osteogenesis ImpeRfecta (EIR)
This study is to evaluate the safety and efficacy of AGA2115 at three different dose regimens in Chinese adults and adolescents with Type I, III, or IV Osteogenesis imperfecta (OI).
- Trial name
- EIR (NCT07557446)
- Testing
- AGA2115
- Where
- 5 sites in China
- Volunteers
- 48 people
- Sponsor
- Angitia Biopharmaceuticals Guangzhou Limited
Type 1 Diabetes Mellitis, Cognition
Glycemic Control, Brain Structure and Cognition in Youth With Type 1 Diabetes (T1DM)
LO5 study: The investigators are inviting a new group of youth (ages 7-16) who have been recently diagnosed with type 1 diabetes and their non-diabetic siblings.
- Trial name
- LO5/HY5 (NCT00879203)
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Arterial Hypertension
The Role of Genetic Factors in the Development of Arterial Hypertension in the Kazakh Population
This is a GWAS study that aims to identify possible candidate genes associate to arterial hypertension by exploring single nucleotide polymorphism (SNP) in a group of arterial hypertension, in the Kazakh population.
- Trial name
- NCT05088486
- Testing
- DNA analysis
- Where
- Kazakhstan
- Volunteers
- 1,200 people
- Sponsor
- Asfendiyarov Kazakh National Medical University
Turner Syndrome
Social Cognition and Turner Syndrome
Monocentric multidisciplinary study (psychologists, endocrinologists, psychiatrists, and molecular biologists) to characterize social cognition in adolescents with Turner syndrome (TS).
- Trial name
- COGNITUR (NCT01687842)
- Testing
- Evaluation of 45,X Turner syndrome patients
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Diabetes Mellitus, Pre Diabetes
Development and Validation of DM and Pre-DM Risk Prediction Model
Many DM and pre-DM remain undiagnosed. The aim is to develop and validate a risk prediction function to detect DM and pre-DM in Chinese adults aged 18-84 in primary care (PC). The objectives are to: 1.
- Trial name
- NCT04881383
- Testing
- OGTT and HbA1c
- Where
- Hong Kong
- Volunteers
- 1,014 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Autism
Family-Centered Implementation of Parent Training for Autistic Toddlers in Early Intervention
Early Intervention (EI) systems are ill-equipped to serve the many children 12 to 36 months with early signs or a diagnosis of autism spectrum disorder (ASD).
- Trial name
- NCT07471594
- Testing
- Parent Training
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Stroke
Development of an Intelligent Balance Training System Providing Weight-bearing Feedback in Stroke Patients
The sit-to-stand and dynamic weight-shifting ability of stroke patients is highly associated with walking performance. Therefore, in order to improve the dynamic weight-shifting ability in sit-to-stand and parallel or tandem…
- Trial name
- NCT04841161
- Testing
- Balance function, gait ability, weight- distribution and weight-shifting, Weight- distribution and weight-shifting training program
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Insulin Resistance
Effects of Sourdough Fermentation Duration and Acid Development on Postprandial Blood Glucose in Prediabetic Adults
The primary intervention for management of prediabetes is lifestyle changes. Eating healthier and increasing physical activity was found to slow the progression of prediabetes into diabetes, reduce the risk of other diseases like…
- Trial name
- NCT06925451
- Testing
- sourdough bread 24, sourdough bread 48, sourdough bread 72
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Arizona State University
Development; Delayed, Mental, Anxiety
Adaptive Care in the Perioperative Setting
The overall purpose for conducting this research is to improve the safety and efficacy of care for perioperative patients who have developmental delays and behavioral challenges.
- Conditions
- Development; Delayed, Mental, Anxiety, Situational Anxiety, Fear of Other Medical Care
- Trial name
- ACT (NCT03353129)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
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