Clinical trials: Development Disorders
Secondary Prevention of Coronary Heart Disease
The Gentle Cardiac Rehabilitation Study
The purpose of this study is to develop a tai-chi based exercise program designed for patients who recently had a heart attack and do not wish, or are unable, to attend traditional cardiac rehabilitation.
- Trial name
- NCT02165254
- Testing
- PLUS, LITE
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- The Miriam Hospital
Growth Hormone Deficiency Without Epiphyseal Closure
Ngenla Subcutaneous Injection Special Investigation
The purpose of this study is to learn about the long-term safety and effects of Ngenla. Ngenla is approved for treatment of GHD (Growth hormone deficiency) without epiphyseal closure under daily medical practice.
- Trial name
- NCT05602766
- Testing
- NGENLA (Somatrogon)
- Where
- Japan
- Volunteers
- 1 people
- Sponsor
- Pfizer
Ultrasound Imaging of Anatomical Structures, Musculoskeletal Diseases
Musculoskeletal System Ultrasound Examination Data Collection Study for the Development of an Artificial Intelligence Software
The primary objective of this observational study is to acquire ultrasound images (raw data) encompassing various planes within the musculoskeletal system.
- Trial name
- NCT06025279
- Testing
- Ultrasound Scan
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Smart Alfa Teknoloji San. ve Tic. A.S.
Self-Injurious Behavior, Autism Spectrum Disorder
Using Apollo Neuro in Autistic Children With Self-Injurious Behavior
This study will evaluate the feasibility and acceptability of the Apollo Neuro, a wearable vibrotactile sensory device, in autistic children who engage in self-injurious behavior (SIB).
- Trial name
- NCT07648420
- Testing
- Apollo Neuro device
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Virginia Commonwealth University
Osteogenesis Imperfecta
An Exploratory Study of BPS804 Treatment in Adult Patients With Type I, III or IV Osteogenesis Imperfecta
The purpose of this study is to investigate the effect of BPS804 on strength/quality of bone in patients with Type I, III or IV Osteogenesis imperfecta using a special type of CT scanner. Participants will be treated for 1 year.
- Trial name
- Meteoroid (NCT03216486)
- Testing
- BPS804
- Where
- 2 sites in United States
- Sponsor
- Ultragenyx Pharmaceutical Inc
Microcephaly, Congenital Infection
Surveillance of Zika-related Microcephaly in Sub-Saharan Africa and Asia
This study will explore whether ZIKV is currently responsible for neurological complications, and particularly microcephaly, in Aedes-infested regions of Sub-Saharan Africa (SSA) and Asia.
- Trial name
- NCT03922594
- Testing
- Differential diagnosis for infectious causes of microcephaly
- Where
- 8 sites in Cameroon, China and 3 more
- Volunteers
- 150 people
- Sponsor
- Institut Pasteur
Autism Spectrum Disorder (ASD, Sleep Disturbances in Children
Telehealth Exercise Boosts Sleep and Reduces Parental Stress in Autism
This study aims to test whether a physical activity program delivered through telehealth can help improve sleep quality in children with autism spectrum disorder (ASD) and reduce stress and improve well-being in their parents.
- Conditions
- Autism Spectrum Disorder (ASD, Sleep Disturbances in Children, Parental Stress
- Trial name
- NCT07066020
- Testing
- Telehealth-delivered Physical Activity Program for Children with ASD, In-Person Supervised Physical Activity Program, General Health Education Materials
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Hunan Normal University
Conduct Disorder, Oppositional Defiant Disorder
Pathways 2 Success
This study involves a 3-arm randomized controlled trial designed to investigate the feasibility and acceptability of three preventive interventions designed to reduce risk for escalations in adolescent conduct problems.
- Trial name
- NCT06831123
- Testing
- L2B, L2B + App, skills for success
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Minnesota
Cancer, Cardiovascular Diseases
Development of Photoacoustic Tomography
Cancer is one of the leading causes of death internationally. When planning treatment for most cancers, it is important to know how far it has spread, including whether or not the cancer has spread to the local lymph nodes (LNs)…
- Trial name
- NCT03501823
- Testing
- Photoacoustic tomography
- Where
- United Kingdom
- Volunteers
- 27 people
- Sponsor
- University College, London
Intellectual Disability
Development and Validation of the Observatory Battery of Common Eye Disorders for Adults With Intellectual Disability
Background: Around 15% of the global population has some form of disability. Rights to obtain proper health care is an emphasis in the United Nationals Convention on the Right of People with Disability.
- Trial name
- NCT06737627
- Testing
- no intervention
- Where
- 2 sites in Taiwan
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Substance Abuse
Parent-Adolescent Interactions and Adolescent Development
The purpose of this study is to observe parent-adolescent interactions and to examine the parenting behaviors and adolescent emotional and physiological responses that are associated with youth's substance use.
- Trial name
- PAIT (NCT01572441)
- Where
- 2 sites in United States
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- George Mason University
Pectus Excavatum
The Effect of Surgical Repair of Chest on Postural Stability Among Patients With Pectus Excavatum
The goal of this study is to determine the effect of Nuss minimally-invasive repair technique of pectus excavatum (PE) on the postural stability in patients with PE.
- Trial name
- NCT05844800
- Testing
- Nuss repair of Pectus Excavatum, Epidural anesthesia
- Where
- 2 sites in Poland
- Volunteers
- 43 people
- Sponsor
- Poznan University of Physical Education
Lung Cancer
Lung Cancer, Exercise and Force Development
This study evaluates the effectiveness of a supervised one-leg resistance training program in patients with inoperable lung cancer with the primary outcome being rate of force development.
- Trial name
- NCT05778136
- Testing
- Resistance training
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Intellectual Disability, Developmental Disability
Best Practices to Prevent COVID-19 Illness in Staff and People With Serious Mental Illness and Developmental Disabilities in Congregate Living Settings
Best Practices to Prevent COVID-19 Illness in Staff and People With Serious Mental Illness and Developmental Disabilities in Congregate Living Settings is a research study aimed at developing, implementing, and evaluating a…
- Conditions
- Intellectual Disability, Developmental Disability, Axis I Diagnosis, Mental Illness
- Trial name
- NCT04726371
- Testing
- Generic Best Practices, Tailored Best Practices
- Where
- United States
- Volunteers
- 415 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Polycystic Ovary Syndrome, Hyperandrogenism
Metformine and CC Compared With Placebo and CC for Induction Ovulation in PCOS Patients With Insulin Resistant
Polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility which affects 12-21% of the population.Several studies performed evaluate the possible benefit of metformin alone or in combination with…
- Trial name
- NCT02523898
- Testing
- metformine, clomiphene citrate
- Volunteers
- 388 people
- Sponsor
- Semnan University of Medical Sciences
Copy Number Abnormality, Prenatal Diagnosis
Technology Development for Noninvasive Prenatal Genetic Diagnosis Using Whole Fetal Cells From Maternal Peripheral Blood
Amniocentesis (amnio) and chorionic villus sampling (CVS) can reliably detect many smaller DNA/genetic abnormalities that cannot be reliably diagnosed by cell-free noninvasive prenatal testing (NIPT) that is in widespread use.
- Conditions
- Copy Number Abnormality, Prenatal Diagnosis, Genetic Disease
- Trial name
- NCT04285814
- Testing
- Whole Fetal Cell (WFC) Testing
- Where
- 2 sites in United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Columbia University
HCC, CKD
Renal Protocol Protection in CKD Patients
This study aims to investigate whether acceptable image quality is achievable using low contrast media dose and low keV imaging in chronic kidney disease.
- Trial name
- NCT04024514
- Testing
- low dose CT contrast media, Standard dose CT contrast media
- Where
- South Korea
- Volunteers
- 52 people
- Sponsor
- Seoul National University Hospital
Autism Spectrum Disorder
Modular Approach for Autism Programs in Schools
The number of students aged 6-21 years with an educational classification of autism spectrum disorder (ASD) in the United States grew by about 19 times over a 19-year period-from 29,076 in 1995-6 to 545,198 in 2014-2015 (IDEA…
- Trial name
- MAAPS (NCT04533607)
- Testing
- MAAPS
- Where
- 3 sites in United States
- Volunteers
- 120 people
- Sponsor
- May Institute
Rheumatoid Arthritis, Osteoarthritis
A Two Centre Study to Assess the Long-term Performance of the Pinnacle™ Cup With a Metal-on-Metal Bearing in Primary Total Hip Replacement
The purpose of this study is to monitor the performance and determine the metal ion release of the Pinnacle™ Cup with a metal-on-metal bearing combination in the treatment of patients with hip joint disease requiring a total hip…
- Conditions
- Rheumatoid Arthritis, Osteoarthritis, Post-traumatic Arthritis, Collagen Disorders
- Trial name
- NCT00208364
- Testing
- Pinnacle Acetabular Cup System
- Where
- 2 sites in Italy, United Kingdom
- Volunteers
- 163 people
- Sponsor
- DePuy International
Social Media Addiction
4-STEP-Training Program for Social Media Addiction (4-STEP-TPS) Among Young Adults
The goal of this clinical trial is to develop a comprehensive Training Program intervention for social media addiction called the 4-STEP-Training Program for Social Media Addiction (4-STEP-TPS) and to learn if the 4-STEP-TPS will…
- Trial name
- 4-STEP-TPS (NCT06498999)
- Testing
- 4-STEP-Training Program for Social Media Addiction (4-STEP-TPS)
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Government College University Faisalabad
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