Clinical trials: Development Disorders
Osteoporosis
Skeletal Health of Klinefelter Patients
This study compared the bone health of KS patients who were actively monitored in our clinic by dual-energy X-ray absorptiometry (DXA) with that of a control group of healthy volunteers.
- Trial name
- NCT03704987
- Testing
- dual-energy X-ray absorptiometry
- Where
- Turkey (Türkiye)
- Volunteers
- 247 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Acquired Brain Injury
Development of a Soft Robotic Device for Rehabilitation and Assistance of the Upper Limb for People With Neurological Disorders
Development of a soft robotic device for rehabilitation and assistance of the upper limb for people with neurological disorders (FRONTIER)
- Trial name
- FRONTIER (NCT07750314)
- Testing
- FRONTIER Soft Exoskeleton
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Università Vita-Salute San Raffaele
Developmental Coordination Disorder
Gait and Muscle Power Training for Children With Developmental Coordination Disorder
Objectives: To compare the effectiveness of RAS-MPT, RAS alone, MPT alone, and usual care (as a control) for improving the overall gait performance of and reducing falls in children with developmental coordination disorder (DCD)…
- Trial name
- NCT03838614
- Testing
- Rhythmical auditory stimulation gait training and muscle power training (RAS-MPT), Rhythmical auditory stimulation gait training (RAS), Muscle power training (MPT)
- Where
- Hong Kong
- Volunteers
- 76 people
- Sponsor
- The University of Hong Kong
Postoperative Delirium
Electroencephalographic Biomarker to Predict Postoperative Delirium
Acute post-operatory cognitive dysfunction states are one of the most important complications in older patients that underwent surgery. Among them postoperative delirium (POD) is the the most studied.
- Trial name
- NCT05992506
- Testing
- POD risk estimation using PEUMA
- Where
- 2 sites in Chile
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- University of Chile
Obesity, Childhood
Development of an Eating Behavior Risk Score
This study will explore how children's eating behaviors are connected to brain activity and body fat levels. Researchers are especially interested in a behavior pattern called the PACE phenotype, which includes how much children…
- Trial name
- PACE (NCT07266506)
- Testing
- Assessment of PACE Eating Phenotype and Related Behavioral and Neurobiological Measures
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Penn State University
Anxiety, Depression
Transdiagnostic Behavioral Therapy for Anxiety and Depression in Autistic Adolescents
This study tests the effectiveness of a transdiagnostic cognitive behavioral therapy for autistic youth with anxiety and/or depression.
- Conditions
- Anxiety, Depression, Emotional Disorder, Autism
- Trial name
- NCT05738967
- Testing
- Transdiagnostic cognitive behavioral therapy (CBT), Treatment as usual
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Baylor College of Medicine
Osteoarthritis, Hip, Femur Head Necrosis
Efficiency and Safety of Navigation Aids in Total Hip Arthroplasty With Direct Anterior Approach
This retrospective cohort study aimed to evaluate the effectiveness of an imageless navigation system in total hip arthroplasty (THA) via the direct anterior approach (DAA) on a traction table for reducing functional limb length…
- Conditions
- Osteoarthritis, Hip, Femur Head Necrosis, Developmental Dysplasia of the Hip
- Trial name
- NCT07134036
- Testing
- Navigation system, Conventional total hip arthroplasty
- Where
- Taiwan
- Volunteers
- 72 people
- Sponsor
- China Medical University Hospital
Pervasive Developmental Disorders
Social Skills in Children With Autism Spectrum Disorders
To evaluate whether a structured social skills program, called Social Skills Development,is superior to a wait list control group on measures of interpersonal interaction.
- Trial name
- SSD_ASD (NCT02147236)
- Testing
- Social Skills Training
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Yale University
Heart Failure, Pulmonary Hypertension
Development of Novel Physiological CMR Methods in Health and Disease
Physiological cardiovascular stress test plays a crucial role in the assessment of patients with suspected heart disease. There are several methods of cardiac physiological stress tests and each of them offer varied insight into…
- Conditions
- Heart Failure, Pulmonary Hypertension, Myocardial Infarction, Coronary Artery Disease
- Trial name
- NCT03854071
- Testing
- intravenous fluid challenge
- Where
- United Kingdom
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Autism Spectrum Disorder
Hyperthermia and the Amelioration of Autism Symptoms
The febrile hypothesis of Autism Spectrum Disorder (ASD) stems from the observation that clinical symptoms improve during fever.
- Trial name
- NCT01784744
- Testing
- Hydroworx Pool at 98 degrees Fahrenheit, Hydroworx Pool at 102 degrees Fahrenheit
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Montefiore Medical Center
Autism Spectrum Disorder
Effectiveness of a 6-week Hippotherapy Program in Children With Autism Spectrum Disorder
The prevalence of autism spectrum disorders (ASD) has increased dramatically in the last decade. The increasing occurrence of ASD creates an imperative need to test the effectiveness and efficacy mechanisms of appropriate…
- Trial name
- NCT04772898
- Testing
- Hippotherapy
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Creighton University
Leukemia, Myelodysplastic Syndromes
Combination Chemotherapy With or Without Filgrastim and/or Tretinoin in Treating Patients With Acute Myeloid Leukemia
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Colony-stimulating factors such as filgrastim may increase the number of immune cells found in bone marrow…
- Conditions
- Leukemia, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms
- Trial name
- NCT00005863
- Testing
- filgrastim, cytarabine, daunorubicin hydrochloride
- Where
- United Kingdom
- Sponsor
- Medical Research Council
Turner Syndrome, Infertility, Female
Turner Syndrome Minipuberty Study
Rationale: Due to accelerated germ cell loss, infertility is a major problem in girls with Turner syndrome (TS). Therefore, cryopreservation of ovarian tissue or oocytes before exhaustion of the ovarian reserve may preserve…
- Conditions
- Turner Syndrome, Infertility, Female, Premature Ovarian Failure, Gonadal Dysgenesis
- Trial name
- Minipuberty (NCT04189406)
- Testing
- Venapunction
- Where
- 13 sites in Denmark, Germany and 3 more
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Hearing Loss
Bilateral Cochlear Implant Benefit in Young Children
The primary purpose of this study is to track patient outcomes for bilateral cochlear implant recipients in a cohort of 60 children, ages 12 to 36 months at time of surgery, who receive two implants in the same operation or in…
- Trial name
- NCT00424307
- Testing
- HiResolution Bionic Ear System
- Where
- 14 sites in United States, Canada
- Volunteers
- 60 people
- Sponsor
- Advanced Bionics
Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder
Motor Impairments in Children With Autism Spectrum Disorder: a Multimodal Approach
The general goal of the present proposal, Progetto MOSAICO, is the identification of a multimodal panel of neuropsychological, kinematic, neurophysiological, and genetic markers associated with motor abnormalities present in ASD.
- Conditions
- Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder, Intellectual Disability
- Trial name
- MOSAICO (NCT04769011)
- Testing
- Clinical evaluation, Neuropsychological evaluation, Neurophysiological evaluation
- Where
- Italy
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Adrenal Hyperplasia, Congenital
LC-MS / MS Adrenal Steroids Assayed on Dried Blot Spot for the Congenital Adrenal Hyperplasia Neonatal Screening (SPECTROSPOT)
This research uses the Liquid Chromatography coupled to tandem Mass Spectrometry (LC-MS / MS) technique on dried blot spot samples for the neonatal screening of congenital adrenal hyperplasia.
- Trial name
- SPECTROSPOT (NCT03589144)
- Where
- France
- Volunteers
- 132 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Molar Incisor Hypomineralization, Anesthesia, Local
Effect of Silver Diamine Fluoride on Local Anesthesia in Hypomineralized Molars
The purpose of this randomized, controlled clinical study is to evaluate if application of 38% SDF increases the efficacy of local anesthesia during operative dentistry on permanent molars affected by molar-incisor hypoplasia…
- Trial name
- NCT05964387
- Testing
- SDF
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome, Adult Acute Basophilic Leukemia
Azacitidine, Mitoxantrone Hydrochloride, and Etoposide in Treating Older Patients With Poor-Prognosis Acute Myeloid Leukemia
This phase I trial studies the best dose of azacitidine and to see how well it works with mitoxantrone hydrochloride and etoposide in treating older patients with acute myeloid leukemia that has a lower chance of responding to…
- Conditions
- Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome, Adult Acute Basophilic Leukemia, Adult Acute Eosinophilic Leukemia, Adult Acute Megakaryoblastic Leukemia
- Trial name
- NCT01260714
- Testing
- Azacitidine, Etoposide, Laboratory Biomarker Analysis
- Where
- 2 sites in Canada
- Volunteers
- 13 people
- Sponsor
- National Cancer Institute (NCI)
Psychosomatic Disorder
Superficial Supportive Psychotherapy Model and Its Effect on Acute Coronary Syndrome Psycho-Neuro-Endocrine Studies
Hypothesis 1. The supportive psychotherapy model can be structured and developed for the non-pharmacologic therapy of acute coroner syndrome patients in intensive cardiac care unit 2.
- Trial name
- NCT04868734
- Testing
- Supportive Psychotherapy
- Where
- Indonesia
- Volunteers
- 80 people
- Sponsor
- Universitas Indonesia
Breast Density, Body Composition
Chilean Maternal & Infant Cohort Study II (CHiMINCs-II)
The Chilean Maternal \& Infant Cohort Study II (ChiMINCs II) is an ongoing cohort that is part of the Chilean Maternal and Infant Nutrition Observatory of the South-East area of Santiago, Chile.
- Conditions
- Breast Density, Body Composition, Nutritional Status, Mental Health Issue
- Trial name
- CHiMINCs-II (NCT03920098)
- Testing
- Nutrition and mental health during pregnancy
- Where
- Chile
- Volunteers
- 1,927 people, healthy volunteers welcome
- Sponsor
- Instituto de Nutrición y Tecnología de los Alimentos
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