Clinical trials: Development Disorders
Autism, Tuberous Sclerosis
Studies of Autistic Patients: Gene Networks and Clinical Subtypes
Background: Researchers who are studying autism spectrum disorders are interested in developing a collection of research samples from both children with autism and healthy individuals, some of whom may be related to the children…
- Trial name
- NCT01092208
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Molar Incisor Hypomineralization
Effectiveness of Pulpotomy in Carious First Permanent Molar
Pediatric dentists frequently encounter deeply carious young permanent first molars (PFM) with Molar Incisor Hypomineralisation (MIH).
- Trial name
- NCT06137391
- Testing
- Vital Pulp Therapy
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Autism Spectrum Disorder
Emergent Multi-Class Imitation Training
The goals of this project are to (a) incorporate empirical findings on imitation training and learning in autistic children into a comprehensive protocol for Applied Behavior Analysis practitioners designed to rapidly facilitate…
- Trial name
- EMIT (NCT05849376)
- Testing
- Emergent Multi-Class Imitation Training
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Rutgers, The State University of New Jersey
Hypomineralization of Enamel, Hypomineralization Molar Incisor
The Association Between MIH and HSPM
Aim of the Study Evaluate association between HSPM and MIH in Egyptian children. Record the prevalence of HSPM and MIH in Egyptian children
- Trial name
- NCT04344340
- Testing
- clinical examination
- Where
- Egypt
- Volunteers
- 190 people
- Sponsor
- Cairo University
Stimulant Use, Stimulant-Related Disorder
The Longitudinal Study of Stimulant Use Disorder
This research is a 5-year observational, longitudinal registry study with no treatment or medication provided as part of participation.
- Conditions
- Stimulant Use, Stimulant-Related Disorder, Healthy
- Trial name
- STIM-RAD (NCT06073340)
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Molar Incisor Hypomineralization
Prevalence And Severity Of Molar Incisor Hypomineralization Among A Group Of Children With Type I Diabetes Milletus.
Determine the prevalence of molar incisor hypomineralization among a group of children with type I diabetes millutes, its severity and treatment need via clinical examination of children with type I diabetes millutes .
- Trial name
- NCT06342089
- Testing
- Type I diabetes milletus
- Volunteers
- 238 people
- Sponsor
- Cairo University
Autistic Disorder
Donepezil HCl & Cognitive Deficits in Autism
This 11-week study will examine the safety and effectiveness of the medication donepezil (Aricept®) compared to placebo for treating cognitive deficits in children and adolescents with Autism Spectrum Disorder.
- Trial name
- NCT00047697
- Testing
- Donepezil HCl
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Pittsburgh
Autism Spectrum Disorder
Probiotics and Oxytocin Nasal Spray on Social Behaviors of Autism Spectrum Disorder (ASD) Children
Because oral probiotics reported to potentially induce endogenous Oxytocin, and Oxytocin has been reported to improve social behaviors, the investigators will conduct a pilot trial to compare the effects of probiotics and…
- Trial name
- NCT03337035
- Testing
- intranasal oxytocin, oral probiotics
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Massachusetts General Hospital
Congenital Heart Disease, Tetralogy of Fallot
Molecular and Cellular Characterization of Cardiac Tissue in Postnatal Development
The study team will use small pieces of human hearts which are removed as part of a required surgical procedure to study different objectives.
- Trial name
- NCT00243776
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Emory University
Marfan Syndrome
Angiotensin Converting Enzyme Inhibitors in Marfan Syndrome
The purpose of this research is to assess the effects of a drug called perindopril on the aorta in people known to have Marfan Syndrome.
- Trial name
- NCT00485368
- Testing
- Coversyl (perindopril)
- Volunteers
- 17 people
- Sponsor
- Bayside Health
Plagiocephaly, Brachycephaly
Cranial Remolding Orthosis Registry
A registry of infants fitted with a cranial remolding orthosis.
- Conditions
- Plagiocephaly, Brachycephaly, Asymmetric Head
- Trial name
- NCT06762691
- Testing
- MyCRO Band, Traditional CRO
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Otto Bock HealthCare LP
Osteopenia
Study of Adults With Low Growth Hormone Who Survived Childhood Cancer Where Treatment Caused Low Bone Density
The purpose of this project is to evaluate the hypothesis that bisphosphonate treatment given to growth hormone deficient patients (regardless of current growth hormone replacement therapy status and without changing that status)…
- Trial name
- NCT00145704
- Testing
- bisphosphonate therapy (risedronate), Vitamin D supplement, Calcium
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- State University of New York - Upstate Medical University
Oral Squamous Cell Carcinoma
Concurrent Radiotherapy and/or Cisplatin With or Without Celecoxib in Patients With Primary Oral Squamous Cell Carcinoma
The research and development of novel anti-tumor agents in oral cancer is slow, the investigation of repositioning use of currently available drugs in clinical, such as a selective cyclooxygenase-2 (COX-2) inhibitor…
- Trial name
- NCT02739204
- Testing
- Celecoxib
- Where
- Taiwan
- Volunteers
- 270 people
- Sponsor
- China Medical University Hospital
Rheumatoid Arthritis
A Study of Duration of Maintained Efficacy in Rheumatoid Arthritis (RA) Patients Off Treatment With MRA(a Development Code of Tocilizumab, an Anti IL-6 Receptor Monoclonal Antibody.)
A 52-week follow up study to investigate the duration of maintenance of efficacy in patients with RA and achieved low disease activity in clinical trials of MRA and stopped the treatment
- Trial name
- NCT00661284
- Where
- 5 sites in Japan
- Volunteers
- 189 people
- Sponsor
- Chugai Pharmaceutical
Acute Respiratory Distress Syndrome ARDS
Driving Pressure-guided Tidal Volume Ventilation in the Acute Respiratory Distress Syndrome
Acute respiratory distress syndrome (ARDS) is associated with high mortality, some of which can be attributed to ventilator-induced lung injury (VILI) when artificial ventilation is not customized to the severity of lung injury.
- Trial name
- DRIVENT (NCT06322758)
- Testing
- Tidal volume customization in the acute respiratory distress syndrome
- Volunteers
- 750 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Autistic Disorder, Constipation
Impact of Improving Gastrointestinal Symptoms on Autism Symptoms and Oxidative Stress
The clinical manifestation of autism spectrum disorder (ASD) is complex, with medical and mental health disruptions that occur with the three core behavioral criteria used for diagnosis (social behavior, communication, restricted…
- Conditions
- Autistic Disorder, Constipation, Gastrointestinal Diseases
- Trial name
- NCT02442115
- Testing
- Treatment of Functional Constipation by
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Children's Hospital Los Angeles
Meningitis, Meningococcal
Safety And Blood Collection Study Of Meningococcal B Rlp2086 Vaccine In Adults
The purpose of this study is to evaluate the safety of an investigational meningococcal B rLP2086 vaccine in adults and to obtain blood samples from immunized subjects for use in assay development.
- Trial name
- NCT00780806
- Testing
- meningococcal B rLP2086 vaccine candidate, Blood draw
- Where
- 3 sites in Australia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Postoperative Delirium, Postoperative Cognitive Dysfunction
Development of a Prediction Model for Delirium After Cardiac Surgery Using a Novel Self-Administered Preoperative Cognitive Assessment Tool
This observational cohort study is designed to validate the CogCheck application as a risk prediction tool for postoperative delirium in patients undergoing cardiac surgery.
- Conditions
- Postoperative Delirium, Postoperative Cognitive Dysfunction, Cognitive Decline, Cognitive Impairment
- Trial name
- CogCheck-Valid (NCT03360838)
- Testing
- CogCheck
- Where
- Switzerland
- Volunteers
- 475 people
- Sponsor
- University Hospital, Basel, Switzerland
Encopresis, Autistic Disorder
An Interdisciplinary Approach to the Treatment of Encopresis in Children With Autism Spectrum Disorders
The purpose of this study is to try to treat bowel movement (BM) accidents differently with children with autism spectrum disorder (ASD). The study will use over-the-counter (OTC) medications to evoke predictable bowel movements.
- Trial name
- NCT02383758
- Testing
- Glycerin Suppository, Bisacodyl suppository, Senna
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Emory University
Alcohol Withdrawal Syndrome
The "Prediction of Alcohol Withdrawal Severity Scale" (PAWSS)
Although there are several tools that can be used to evaluate the severity of ongoing alcohol withdrawal syndrome (AWS), there is no available tool that can predict which patients are at risk for developing AWS at the time…
- Trial name
- PAWSS (NCT01637415)
- Where
- United States
- Volunteers
- 409 people, healthy volunteers welcome
- Sponsor
- Stanford University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.