Clinical trials: Development Disorders
Autism
A Study of Oxytocin in Children and Adolescents With Autistic Disorder
The investigators propose to conduct this pilot study to evaluate oxytocin as a supplemental treatment for improving social difficulties in individuals with autism.
- Trial name
- Oxytocin (NCT01308749)
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of North Carolina, Chapel Hill
TSC
TSC Remote Assessment and Intervention
The investigators propose a study to adapt an evidence-based caregiver training program to improve access in order to better serve the TSC community.
- Trial name
- TRAIN (NCT04698538)
- Testing
- JASPER
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of California, Los Angeles
Breast Cancer, Locally Advanced Breast Cancer (LABC)
Patient-Derived Organoids to Functionally Characterize Chemotherapy Resistance in Breast Cancer
This prospective observational study aims to functionally characterize chemotherapy resistance in patients with locally advanced breast cancer undergoing neoadjuvant chemotherapy.
- Trial name
- BC-PDO (NCT07516626)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Atlas University
Severe Autoimmune Encephalitis
Risk Prediction Model for Severe Autoimmune Encephalitis
A prospective study aims to establish a multicenter clinical diagnosis and treatment database for patients with autoimmune encephalitis (AE).
- Trial name
- NCT06697678
- Testing
- No Intervention: Observational Cohort
- Volunteers
- 1,000 people
- Sponsor
- Xuanwu Hospital, Beijing
Breast Neoplasms
Delphinus SoftVue Prospective Case Collection - ARM 2
The SoftVue™ is a whole breast ultrasound system with an automated scanning curvilinear ring-array transducer that employs UST. It is currently cleared under FDA 510(k) K123209 and K142517 for use as both a B-mode ultrasonic…
- Trial name
- SV PCC ARM2 (NCT02977247)
- Testing
- Non-Interventional, Automated Whole Breast Ultrasound
- Where
- 10 sites in United States
- Volunteers
- 1,150 people
- Sponsor
- Delphinus Medical Technologies, Inc.
Premature Birth
Vermont Intervention: Effect on Joint Attention Skills Between Parents and Moderate/Late Preterm Infants in the First Year of Life
The purpose of this study is to investigate if the effects of the Vermont intervention, implemented by nurses in a Neonatal Intensive Care Unit (NICU), can influence social interaction and joint attention skills between parents…
- Trial name
- NCT00245843
- Testing
- Mother Infant Transaction Program (MITP)
- Where
- Norway
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Ullevaal University Hospital
Suspicion of Bladder Cancer, NMIBC Surveillance
Bladder EpiCheck Product Development Study
This is a prospective, observational study to support the development of the Bladder EpiCheck kit by collecting urine samples from subjects suspected to have a bladder tumor or under NMIBC surveillance.
- Trial name
- NCT07514143
- Testing
- Bladder EpiCheck
- Where
- 2 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Nucleix Ltd.
Parkinson Disease
Development and Research of an Individualized Intelligent Platform for Rehabilitaion in Parkinson's Disease
The present study aims to compare the clinical efficacy of intelligent POWER therapy, intelligent LSVT-BIG therapy, and the three exercise models currently in clinical use.
- Trial name
- NCT03212014
- Testing
- LSVT-BIG, POWER, Traditional rehabilitation
- Where
- Taiwan
- Volunteers
- 75 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Endometrial Carcinoma
Development of a New Early Detection Test to Reduce Racial Disparities in Endometrial Cancer (EC) Death Rates
This phase I trial investigates the development of a new early detection test to reduce racial disparities in endometrial cancer death rates.
- Trial name
- NCT04474184
- Testing
- Biospecimen Collection, Focus Group, Survey Administration
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Offspring, Adult, Lifestyle
Factors Affecting Newborn Body Composition and Later Health in Helsinki Birth Cohort 2018-2022
In Helsinki Birth Cohort 2018-2022 a large, longitudinal and well-phenotyped birth cohort of infants and their parents will be established.
- Conditions
- Offspring, Adult, Lifestyle, Obesity, Childhood, Pregnancy Related
- Trial name
- HeBiCo (NCT03765684)
- Where
- Finland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Prostate Cancer
Expression of Tumor Markers in Circulating Tumor Cells of Metastatic Hormone-sensitive Prostate Cancer
As prostate cancer progresses, tumor cells dissociate and enter the bloodstream. Considered a "liquid biopsy," these circulating tumor cells (CTC) can show how a patient's cancer evolves and responds to treatments.
- Trial name
- NCT02723526
- Testing
- Blood drawing
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Fudan University
Substance Use (Drugs, Alcohol), Health Risk Behaviors
Pilot of a Drug Education Curriculum for Middle and High School Students
The goal of this pilot study is to measure the feasibility, sustainability, and acceptability of a drug education curriculum (IDECIDE) in middle and high students who have endorsed past-month substance use.The main question it…
- Conditions
- Substance Use (Drugs, Alcohol), Health Risk Behaviors, Youth, Adolescent Behavior
- Trial name
- iDECIDE (NCT07918963)
- Testing
- iDECIDE
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Short Stature Born Small for Gestational Age (SGA)
Long Term Study of Genotropin (Somatropin) for Short Children Born Small for Gestational Age (SGA)
To assess the long-term safety of Genotropin(somatropin) on Small for Gestational Age (SGA) without epiphyseal closing.
- Trial name
- NCT01859949
- Testing
- Genotropin (somatropin)
- Where
- 19 sites in Japan
- Volunteers
- 62 people
- Sponsor
- Pfizer
Autism Disorder
Triadic Interactions of Families With Autism and Oxytocin
The study will investigate the effects of an intranasal administration of oxytocin (OT) to parents of children with autism spectrum disorders (ASD) on the quality of mother-father-child interactions.
- Trial name
- TAO (NCT01912378)
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Physical Activity, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse)
Expanded Game Squad for Neurodiverse Youth
The proposed study will pilot the use of an adapted Game Squad intervention aimed at improving physical activity and other important health behaviors (nutrition, sleep hygiene, screen time habits) for children and adolescents…
- Conditions
- Physical Activity, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Health Behavior, Developmental Disorder
- Trial name
- NDGameSquad (NCT03665415)
- Testing
- NDGameSquad
- Where
- 2 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Merrimack College
Autism Spectrum Disorder, Parent-Child Relations
Parent Video Feedback Intervention Study
The purpose of this study is to use a randomized controlled trial to test the effectiveness of parent coaching sessions using video-based feedback, compared to the sessions without the use of video-based feedback on parent…
- Trial name
- NCT03397719
- Testing
- Treatment Condition, Control Group
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Weill Medical College of Cornell University
Growth Hormone Deficiency
Low and Conventional Dose of Somatropin in Growth Hormone Deficient Adult Patients
An international study in which patients with GHD were randomized to receive somatropin at a dose of either 3 microg/kg/day or 6 microg/kg/day for the first three months.
- Trial name
- NCT00570011
- Testing
- Somatropin
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- Eli Lilly and Company
Autism Spectrum Disorder
Opt-In Early Pilot Study
Latinx and Rural-living children with diagnosed or suspected autism have especially long wait times for diagnoses and intervention, up to a year or even more.
- Trial name
- NCT06908187
- Testing
- Opt-In Early Latinx intervention, Opt-In Early Rural Intervention
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- Oregon Health and Science University
Prostate Cancer
Development and Evaluation of a Therapeutic Education Intervention in Prostate Cancer Patients Treated With Radical Prostatectomy to Improve Their Sexuality
Prostate cancer is the most common cancer in France (54,000 cases in 2011). About 20,000 radical prostatectomies (PR) per year are performed.
- Trial name
- PRODUCAN (NCT03572621)
- Testing
- Therapeutic education, Collection of data concerning their sexuality, Participation
- Where
- 2 sites in France
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Suicidal Ideation, Suicidal
Reward Sensitivity Digital Intervention for Suicide Risk
The goal of this clinical trial is to develop and test an app designed to reduce suicide risk and improve emotional well-being in adolescents.
- Conditions
- Suicidal Ideation, Suicidal, Suicidal Thoughts, Digital Health Intervention
- Trial name
- DIGIReward (NCT07661901)
- Testing
- Suicide prevention treatment
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Pennsylvania
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