Clinical trials: Development Disorders
Autism, Autism Spectrum Disorder
A Kinematic Analysis of Motor Planning and Movement Execution of Children With Autism Spectrum Condition
Autism Spectrum Condition (ASC) is a behavioral syndrome characterized by a severe organizational disorder of thinking and major functions that regulate human adaptation.
- Trial name
- NCT06144775
- Testing
- Kinematics measures
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Genetic Diseases
Decoding Developmental Disorders in Humams
The DEVO-DECODE project aims to align our currently limited knowledge currently limited knowledge of the genetic architecture of developmental with our more advanced knowledge of their "phenome".
- Trial name
- devodecode (NCT06260319)
- Testing
- Whole genome sequencing and Genome-Epigenome-Phenome Associations
- Where
- France
- Volunteers
- 720 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Treatment Satisfaction, Participation Rate, Patient
Mindfulness Based Stress Reduction for Intellectually Able Autistic Adults
This project evaluates mindfulness based stress-reduction (MBSR), adjusted and manualized for intellectually able autistic adults. MBSR is a skills training program based on further development of cognitive behavioral therapy.
- Conditions
- Treatment Satisfaction, Participation Rate, Patient, Quality of Life, Mental Illness
- Trial name
- NCT05244265
- Testing
- Mindfulness-based stress reduction (MBSR), Treatment as usual (TAU)
- Volunteers
- 140 people
- Sponsor
- Karolinska Institutet
Leukemia
Combination Chemotherapy, Interleukin-2, and Peripheral Stem Cell Transplant in Treating Patients With Acute Myeloid Leukemia
RATIONALE: Giving combination chemotherapy before a peripheral blood stem cell transplant stops the growth of cancer cells by stopping them from dividing or killing them.
- Trial name
- NCT00004128
- Testing
- aldesleukin, filgrastim, busulfan
- Volunteers
- 2,000 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Pulp Necrosis, Regeneration
Regeneration of Pulp-Dentin Development in Teeth With Necrotic Pulps and Immature Roots
This multi-center exploratory clinical trial is a randomized trial designed to test whether a regenerative endodontic procedure using tissue engineering principles (REGENDO), or a revascularization (REVASC) endodontic procedure…
- Trial name
- NCT01976065
- Testing
- Triple Antibiotic Paste, Standard Treatment
- Where
- 4 sites in United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Kenneth Hargreaves
Endothelial Dysfunction, Inflammation in Cardiopulmonary and Vascular Disease States
Samples From Human Subjects to Facilitate Basic, Translational and Clinical Research
Background: This study is designed to provide samples to help us study the genes your blood cells are making as well as the proteins, sugars, fats, vitamins and other metabolites found in your blood or urine.
- Conditions
- Endothelial Dysfunction, Inflammation in Cardiopulmonary and Vascular Disease States, Healthy Volunteers
- Trial name
- NCT03253705
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Autism Spectrum Disorder
Cognoa Autism Spectrum Disorder (ASD) Digital Therapeutic Engagement and Usability Study
Cognoa will measure usability, engagement with the device, and changes in parent-reported socialization during a 4-week period of intervention at home with the Cognoa ASD therapeutic device.
- Trial name
- NCT04326231
- Testing
- Usability assessment of Cognoa ASD Therapeutic Device
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Cognoa, Inc.
Phlebitis
THE EFFECT OF COLD APPLICATION ON THE DEVELOPMENT OF PHLEBITIS IN PATIENTS RECEIVING INTRAVENOUS AMIODARONE TREATMENT.
This study, which has a quasi-experimental, prospective, and open-label randomized controlled design, was conducted to examine the effect of cold application on the development of phlebitis in patients receiving IV amiodarone…
- Trial name
- NCT05058053
- Testing
- Cold application
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Saglik Bilimleri Universitesi
Malnutrition
The Impact on School Feeding on Children's Growth and Development
In order to improve child nutrition, the Poverty Reduction Strategy adopted by the Government of Bangladesh (GoB) has called for the initiation of a school feeding programme for primary school children living in poor and…
- Trial name
- schoolfeed (NCT03263377)
- Testing
- The school feeding intervention
- Volunteers
- 3,006 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Hydrocephalus
Improving Infant Hydrocephalus Outcomes in Uganda
Neonatal postinfectious hydrocephalus (PIH) is a major public health problem in East Africa.The standard treatment has long been placement of a ventriculoperitoneal shunt (VPS) but these devices require life-long maintenance and…
- Trial name
- NCT03650101
- Testing
- ETV/CPC
- Where
- 3 sites in United States, Canada and 1 more
- Volunteers
- 400 people
- Sponsor
- Boston Children's Hospital
Autism Spectrum Disorder
PEACE for ImPACT Study
Investigators will test the impact of the PEACE implementation toolkit and determine the level of implementation support needed to improve early intervention providers use of caregiver coaching with families of young children…
- Trial name
- NCT06374381
- Testing
- PEACE Online Resources, PEACE Weekly Group Facilitation, PEACE Weekly Individual Facilitation
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Intellectual Disability, Variable
A Pilot Project to Facilitate Dental Care and Reduce Barriers For Youth With Disabilities
This randomized clinical trial is an innovative pilot project to determine the acceptance and impact of telehealth visits on youth with intellectual and developmental disabilities (IDD), their caregivers, and dentists.
- Trial name
- NCT06710483
- Testing
- Pre-Dental Telehealth (PDT)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Boston University
Prematurity, Neurodevelopmental Disorder
Effect of Early L-Carnitine Supplementation on Neurodevelopmental Outcomes in Very Preterm Infants
Preterm infants are vulnerable to brain injury, nutritional deficiencies and poor early growth which places them at increased risk for developmental problems later in life.
- Conditions
- Prematurity, Neurodevelopmental Disorder, Carnitine Deficiency
- Trial name
- NCT01783041
- Testing
- L-carnitine, 5% Dextrose
- Where
- 2 sites in United States
- Volunteers
- 144 people
- Sponsor
- Montefiore Medical Center
Growth Hormone Deficiency
A Long-Term Safety Study of Somavaratan in Japanese Children With Growth Hormone Deficiency
This study is a multi-center, open-label safety study assessing long-term somavaratan administration.
- Trial name
- NCT03145831
- Testing
- Somavaratan
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Versartis Inc.
Autism, Emotion Regulation Difficulties
Enhancing Emotion Regulation in Children With Autism Through Extended Reality
Pilot study on the development of an Extended Reality (XR) application to support emotion regulation in children with Autism Spectrum Disorder (ASD) (random assignment to an experimental group, N = 10, and a control group, N =…
- Trial name
- ERAC-XR (NCT07838272)
- Testing
- Extended Reality, Emotion regulation coaching
- Where
- Austria
- Volunteers
- 24 people
- Sponsor
- Johannes Kepler University of Linz
Colorectal Cancer, Colorectal Adenocarcinoma
Irinotecan Plus Brivanib in Metastatic Colorectal Cancer (CRC) Enriched for Elevated Levels of Plasma FGF
The goal of this clinical research study is to learn if adding brivanib to irinotecan can help control the disease in patients with colorectal cancer that has spread. The safety of this drug combination will also be studied.
- Trial name
- NCT01367275
- Testing
- Brivanib, Irinotecan
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- M.D. Anderson Cancer Center
Autism Spectrum Disorder, Autism
Oral Health Care in Autism Spectrum Disorder
Persons with autism spectrum disorder (ASD) are characterized by impairments in social interactions, speech and communication, restricted patterns of behaviour, and unusual sensory sensitivities.
- Trial name
- CREASED (NCT03830541)
- Testing
- Oral care delivery analysis in participants with ASD
- Volunteers
- 52 people
- Sponsor
- University of Novi Sad
Burnout, Professional, Emotional Intelligence
The READ-SG Study: Effect of Peer-Facilitated Small Group Discussions
This study evaluates the effect of peer facilitated monthly small group topic-based small group discussions on various themes common to physician training that pertain to aspects of humanism on rates of burnout.
- Conditions
- Burnout, Professional, Emotional Intelligence, Peer Influence
- Trial name
- READ-SG (NCT03163251)
- Testing
- READ-SG Sessions
- Where
- United States
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Columbia University
Child Development, Premature Birth
Students Education Training in Emotional Connection
The purpose of this study is to assess the effectiveness of different educational modules in training graduate students from Columbia University Irving Medical Center campus and from the Columbia School of Social Work to assess…
- Trial name
- NCT03680001
- Testing
- Training in Rating Emotional Connection
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Columbia University
Stroke, Stroke Rehabilitation
Video-based Sit-to-stand Evaluation for Stroke Patients
The purpose of this study is to develop and validate a novel video-based postural evaluation tool designed to objectively measure the quality and dynamics of the Sit-to-Stand (STS) motion in stroke patients, specifically allowing…
- Trial name
- NCT07359001
- Testing
- Observation
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- Sahmyook University
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