Clinical trials: Development Language Disorder
Developmental Language Disorder
Syntactic Intervention for Cantonese-speaking Children With DLD
The goal of this clinical trial is to compare the efficacy of explicit vs. implicit intervention on subject relative clause production in Cantonese-speaking children with Developmental Language Disorder (DLD).
- Trial name
- NCT06954194
- Testing
- Explicit intervention (Shape Coding+syntactic priming), Implicit intervention (syntactic priming only)
- Where
- Hong Kong
- Volunteers
- 32 people
- Sponsor
- The Hong Kong Polytechnic University
Autism Spectrum Disorder, Language Disorders
Treatment of Social and Language Deficits With Leucovorin for Young Children With Autism
The primary objective of this study is to evaluate the cognitive and behavioral effects of liquid leucovorin calcium on young children with autism spectrum disorder (ASD) and determine whether it improves social communication as…
- Trial name
- NCT04060030
- Testing
- Levoleucovorin Calcium
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Southwest Autism Research & Resource Center
Autism Spectrum Disorder, Complication of Prematurity
Correlation of CXCR4 Expression in Premature Infants With a Diagnosis of Autism at 24 Months
Preterm children are at increased risk for autism spectrum disorders, with an estimated rate of 10%. In the US, about 1 in 8 pregnancies ends with a premature birth.
- Trial name
- ASD-CXCR4 (NCT01686685)
- Where
- Israel
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Urinary Stones, Prostate Cancer
Development of an AI-Agent for Urological Disease Diagnosis and Treatment
Urological diseases such as urinary stones, prostate cancer, and bladder cancer are very common and often require highly specialized diagnosis and treatment.
- Conditions
- Urinary Stones, Prostate Cancer, Bladder Cancer
- Trial name
- NCT07721935
- Where
- 3 sites in China
- Volunteers
- 2,000 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Language Development Disorders, Learning Disorders
Building Complex Language
This study is designed to examine how much therapy is needed in order to make significant gains in knowledge and use of complex sentences.
- Trial name
- NCT01337232
- Testing
- Complex sentence treatment protocol
- Where
- 2 sites in United States
- Volunteers
- 31 people
- Sponsor
- Governors State University
Reading Disorder, Developmental
Camp SMART Speech to Print Summer Literacy Camp
This project aims to explore the feasibility and efficacy of a 6-week, intensive summer literacy intervention provided to children in 1st-3rd grades.
- Trial name
- NCT06442098
- Testing
- CAMP SMART Literacy Summer Camp
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- San Diego State University
Autism Spectrum Disorder
How Simplified Language Affects Comprehension and Learning in Young Autistic Children
The long-term study goal is to experimentally evaluate the components (and likely active ingredients) of early language interventions for young children with ASD.
- Trial name
- PALS (NCT05707923)
- Testing
- Linguistic simplification
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Michigan State University
Language Development
Language Development in Preterm Children
This research investigates the ways in which preterm birth affects how very young children learn to speak and understand language, and how older children gain efficiency in language processing.
- Trial name
- NCT01599780
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Stanford University
Joint Engagement + Enhanced Milieu Training, Joint Engagement + Enhanced Milieu Training+Augmentative Communication (AAC)
Developmental and Augmented Intervention for Facilitating Expressive Language
This study will contrast two experimental treatment conditions by testing whether joint attention/joint engagement intervention using spoken communication (JAE-EMT) results in better outcomes than joint attention/joint engagement…
- Trial name
- CCNIA (NCT01013545)
- Testing
- JAE Intervention
- Where
- 3 sites in United States
- Volunteers
- 96 people
- Sponsor
- Autism Speaks
Autism Spectrum Disorder
Training Early Social Language in Autism
The aim of the study is to determine whether a targeted behavioral intervention can lead to both changes in early communication skills and in neural responses in toddlers and preschoolers with autism.
- Trial name
- TESLA (NCT03427138)
- Testing
- Jasper, Parent Education
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Language Impairment
Feasibility of Omega-3 Supplementation for Children With Language Impairments
The primary objective of this study is to obtain preliminary (pilot) data regarding the feasibility of using dietary omega-3 supplementation in children with significant delays in language skills; a related secondary objective is…
- Trial name
- NCT01640106
- Testing
- Omega-3
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- Shuvo Ghosh
Autism Spectrum Disorder
Development of Sensory Based Narrative Intervention
The goal of this study is to develop a sensory based narrative intervention and see its effect on vocabulary development in children with autism spectrum disorder.
- Trial name
- NCT06141382
- Testing
- English Langugae-Sensory based narrative intervention, English Language-Narrative intervention, Urdu Langusge-Sensory based narrative intervention
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University
Autism Spectrum Disorders
Transcranial Direct Current Stimulation and Autism
This research is being done to determine whether transcranial direct current stimulation (tDCS) can improve certain mental abilities, such as speech, language and other efforts at communication in individuals with autism.
- Trial name
- NCT01603225
- Testing
- Transcranial Direct Current Stimulation (tDCS)
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Johns Hopkins University
Developmental Language Disorders
Treating Complex Grammar Knowledge Deficits in School-Age Children With Developmental Language Disorder
The goal of this project is to compare the relative effectiveness of two novel treatments to improve the complex grammar knowledge of school-age (8-11-year-old) children with developmental language disorder (DLD).
- Trial name
- DLD Treatment (NCT06911138)
- Testing
- Behavorial
- Where
- 4 sites in United States
- Volunteers
- 150 people
- Sponsor
- Ohio University
Developmental Dyslexia, Developmental Language Disorder
Dynamic Assessment of the Risk for Language and Reading Disorders in Monolingual and Multilingual Children
The project represents the completion of a part of the recently concluded European project MultiMind, in which a computer platform called MuLiMi was developed and validated.
- Trial name
- NCT06937255
- Testing
- computerized Dynamic Assessment
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Autism Spectrum Disorder
School-Age Children With Autism With Limited Expressive Language Skills
This project will address a major challenge to the field of autism research: improving expressive communication in children with autism who have reached school age but have not acquired functional spoken language (non-verbal…
- Trial name
- NCT01529580
- Testing
- Non-Verbal School Aged Children with Autism (NVSACA) Intervention
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Cognitive Change, Growth; Stunting, Nutritional
The Sugira Muryango Longitudinal & Spillover Study
The Early Childhood version of Sugira Muryango is a family-based, home-visiting intervention targeted at early childhood development and implemented with families living in extreme poverty in three districts of Rwanda.
- Conditions
- Cognitive Change, Growth; Stunting, Nutritional, Language, Depression
- Trial name
- NCT05405400
- Where
- 3 sites in Rwanda
- Volunteers
- 2,932 people, healthy volunteers welcome
- Sponsor
- Boston College
Developmental Language Disorder
The Effect of Prior Learning on Treatment of Morpheme Errors
This is a small-scale treatment study designed to determine which teaching methods result in the best learning. Treatment focuses on helping children with a developmental language disorder learn parts of grammar.
- Trial name
- NCT05953077
- Testing
- Conversational recasting
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Arizona
Dyslexia, Developmental
Tackling Two of the Most Important Unresolved Tasks in Reading Intervention
An important question in education is how to help young children who struggle to learn to read despite being well-taught in their regular classrooms.
- Trial name
- NCT06403007
- Testing
- Phonics plus morphology, Phonics plus set-for-variability
- Where
- 2 sites in Canada
- Volunteers
- 964 people
- Sponsor
- York University
Hearing Loss, Speech and Language Development Delay Due to Hearing Loss
Teletherapy in Children Who Are Deaf and Hard of Hearing
This study seeks to determine the effectiveness of speech/language teletherapy to address disparities in speech and language outcomes in children who are deaf or hard-of-hearing (D/HH).
- Trial name
- NCT04928209
- Testing
- Speech-Language Teletherapy
- Where
- 5 sites in United States
- Volunteers
- 210 people
- Sponsor
- University of California, San Francisco