Clinical trials: Developmental Delay
Autism Spectrum Disorder, Autism
Mitochondrial Dysfunction in Autism Spectrum Disorder
Researchers at Arkansas Children's Hospital Research Institute are conducting a study about mitochondrial function in children. The study involves up to 5 visits to Arkansas Children's Hospital with fasting blood draws…
- Conditions
- Autism Spectrum Disorder, Autism, Mitochondrial Disease, Developmental Delay
- Trial name
- Mito (NCT02000284)
- Where
- United States
- Volunteers
- 297 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Infant Development, Sensory Disorder
The Prechtl's General Movement Assessment, Hammersmith Infant Neurological Examination and Sensory Profile-2
In the Neonatal Intensive Care Unit (NICU), infants encounter many sensory stimuli (excessive noise, bright lights, painful medical applications, etc.) that are not present in the uterus.
- Conditions
- Infant Development, Sensory Disorder, Sensory Processing Disorder, Motor Delay
- Trial name
- highrisk (NCT05217199)
- Testing
- Measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Developmental Delay, Child Development
Validity and Reliability of Indonesian Translated Ages and Stages Questionnaires - Third Edition (ASQ-3) as a Screening Tool for Developmental Delay in 1-12 Months Old Children
This study aimed to provide the validity and reliability of the Indonesian ASQ-3 questionnaires as a screening tool for developmentally delayed children aged less than one year old. This study was divided into 2 phases.
- Conditions
- Developmental Delay, Child Development, Child Development Disorder, Global Developmental Delay
- Trial name
- NCT05398900
- Where
- Indonesia
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Sarcoidosis, Diabetes Mellitus
A Suspected Association Between Sarcoidosis and Development of Diabetes Mellitus
The purpose of the study is to determine the characteristics of patients with diabetes and sarcoidosis and to compare them with those of patients with diabetes and no sarcoidosis.
- Trial name
- NCT03805633
- Testing
- Venous blood sample, Ultrasound of pancreas
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Development Delay, Social Skills
Home-Based Social Skills Intervention for Young Children With Developmental Delays
The goal of this clinical trial is to learn about how parent training can be used to teach a social skills intervention for their young child with developmental delays.
- Conditions
- Development Delay, Social Skills, Parents
- Trial name
- NCT06184243
- Testing
- Parent Training, Video Modeling
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Gross Motor Development Delay
The Effects of Playful Pathways
The purpose of this study is to evaluate infants ages 0-6 months of age before and after an 8 week developmental and educational "caregiver and baby" interactive program as well as 3 month following the conclusion of the program.
- Trial name
- NCT06139549
- Testing
- Gross motor development group session
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Arkansas Colleges of Health Education
Iron Deficiency
Delayed Cord Clamping and Infant Brain Study
The purpose of this study is to determine if delaying cord clamping at the birth of term infants effects the early brain development (myelin deposition)as determined by quantitative MRI at 4 and 10 months and developmental…
- Trial name
- IBS (NCT01620008)
- Testing
- Delayed Cord Clamping
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Rhode Island
Obesity, Genetic Disorder
Brain-Derived Neurotrophic Factor in Obesity and Brain Function
Background: Prader-Willi syndrome (PWS) and MC4R genetic mutations are two conditions that can cause problems with appetite regulation. People with PWS often have behavior and thinking problems.
- Conditions
- Obesity, Genetic Disorder, Mental Retardation, Developmental Delay
- Trial name
- NCT01517048
- Where
- 2 sites in United States, Canada
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Developmental Disabilities
The Investigation of Children With Developmental Delay and Children's Rehabilitation Common Case
Children with developmental disabilities and children's rehabilitation common case investigation: Long-term follow-up study.
- Trial name
- NCT02686931
- Where
- Taiwan
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Groin Injury
Comparison of the Effect of Copenhagen Adduction Exercises Performed at Different Load-intensity
The aim of our study is to compare the effects of the Copenhagen adduction exercise, performed at different loading intensities, on hip muscle strength development, performance, flexibility, and delayed onset muscle soreness.
- Trial name
- NCT06104722
- Testing
- High-intensity Copenhagen adduction exercise, Low-intensity Copenhagen adduction exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Respiratory Distress, Hypoglycemia
Observational Study of Infants Born at 34 to 37 Weeks of Gestation Until the Age of 1 Year
Late preterm infants are at an increased risk for short and long term morbidity (during the 1st year of life, their neurodevelopmental status may also be delayed as compared to infants born at term).
- Conditions
- Respiratory Distress, Hypoglycemia, Feeding Intolerance, Jaundice
- Trial name
- NCT00550069
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Gestational Diabetes Mellitus in Pregnancy, Cognitive Impairment
Gestational Diabetes Mother-infant Cohort
The bi-directional dynamic cohort study is to learn about the effects of prenatal exposure to high blood glucose levels and postnatal nurturing environment factors on delayed language development in children.
- Conditions
- Gestational Diabetes Mellitus in Pregnancy, Cognitive Impairment, Cohort Study
- Trial name
- NCT06021691
- Testing
- Acquired nurturing environment
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Gansu Provincial Maternal and Child Health Care Hospital
Developmental Disabilities, Language Development Disorders
Preventing Learning Problems in Young Children: A Public Health and Physician-Based Outreach
This study will evaluate a program to prevent learning problems in children. The program is an inexpensive public health outreach program designed for families living in poverty and is administered through pediatricians' offices…
- Trial name
- NCT00110292
- Testing
- Age-specific parenting newsletters and developmental toys, Parent-completed Ages & Stages Questionnaires, Clinic-based distribution of children's books
- Where
- 2 sites in United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Intellectual Disability, Developmental Delay
Establishing the Clinical Utility of First StepDx PLUS and NextStepDx PLUS Study
The study uses a randomized controlled study design of pediatric neurologists and developmental pediatricians and front-line (primary care) pediatricians to determine if use of FirstStepDx PLUS and Next StepDx PLUS are associated…
- Trial name
- NCT02414438
- Testing
- FirstStepDX PLUS and NextStepDX PLUS Webinar, FirstStepDX PLUS and NextStepDX PLUS Test Results
- Where
- United States
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Qure Healthcare, LLC
Developmental Language Disorder, Language Delay
Using Neuroimaging and Behavioral Assessments to Understand Late Talking
Late talkers (LT), representing 10-20% of children under 3, demonstrate hallmark syntax and vocabulary deficits similar to preschoolers with developmental language disorder.
- Conditions
- Developmental Language Disorder, Language Delay, Language Development
- Trial name
- NCT06156865
- Testing
- Intervention to address late talking
- Where
- 2 sites in Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Toronto
MNRI, Development Delay
Effects of MNRI Therapy on Fine Motor Skills in Children With Developmental Delays.
Developmental delay refers to a child's failure to achieve age-appropriate developmental milestones and may affect multiple developmental domains.
- Trial name
- NCT07764926
- Testing
- MNRI, Conventional Physiotherapy without MNRI
- Where
- Pakistan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Autism Spectrum Disorder, Autism
Treatment Monitoring in Autism Spectrum Disorder (ASD) in Children
The goal of this clinical study is to learn about the utility and performance of the EarliPoint(™) System: Evaluation for Autism Spectrum Disorder to monitor changes in a child's verbal ability, non-verbal learning, and social…
- Conditions
- Autism Spectrum Disorder, Autism, Developmental Delay, Autism, Early Infantile
- Trial name
- MEASURE-ASD1 (NCT05675371)
- Testing
- Assessment by Expert Clinician During Behavioral Intervention (ABA or similar), Assessment by the EarliPoint Assessment For Autism Spectrum Disorder
- Where
- 9 sites in United States
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- EarliTec Diagnostics, Inc
Arrest of Bone Development or Growth, Constitutional Delay of Growth and Puberty
YoUng Adolescents' behaViour, musculoskeletAl heAlth, Growth & Nutrition
More children will survive to adulthood today than at any other point in human history, as evidenced by the proportion of live births and absolute numbers.
- Conditions
- Arrest of Bone Development or Growth, Constitutional Delay of Growth and Puberty, Malnutrition, Child, Gestational Diabetes
- Trial name
- YUVAAN (NCT05603793)
- Testing
- Knowledge, Attitude & Practices
- Where
- India
- Volunteers
- 1,304 people, healthy volunteers welcome
- Sponsor
- Hirabai Cowasji Jehangir Medical Research Institute
Child Developmental Delay, Child Malnutrition
Maternal B12 Supplementation to Improve Infant B12 Deficiency and Neurodevelopment
Vitamin B12 plays a key role in the development and normal functioning of the brain and nervous system. Unborn and new-born infants derive their vitamin B12 stores almost entirely from maternal B12 stores.
- Conditions
- Child Developmental Delay, Child Malnutrition, Maternal Exposure, Vitamin B 12 Deficiency
- Trial name
- MATCOBIND (NCT03783104)
- Testing
- B12 Supplement
- Where
- 2 sites in India, Nepal
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- University College, London
Growth Disorders, Malnutrition, Fetal
Evolutionary Nutrition Pilot: Enhancing Fetal Growth and Brain Development
Globally, 250 million children do not reach their developmental potential and 155 million are stunted, yet few population-based studies have examined the direct effects of nutrient deficiencies on early brain development.
- Conditions
- Growth Disorders, Malnutrition, Fetal, Stunting, Development; Delayed, Malnutrition
- Trial name
- NCT05242224
- Testing
- Evolutionary Nutrition Package
- Where
- Ecuador
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine