Clinical trials: Developmental Delay Disorders
Autism, Autism Spectrum Disorder
Trial of Cannabidiol to Treat Severe Behavior Problems in Children With Autism
There are very few treatments that are effective in reducing severe behavioral problems associated with autism. These behaviors include aggressive and self-harm behaviors, frequent repetitive behaviors and severe hyperactivity.
- Trial name
- NCT04517799
- Testing
- Epidiolex
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of California, San Diego
Autism Spectrum Disorder
The Effect of Tidal Model-Based Psychiatric Nursing Approach on Mothers of Children With Autism Spectrum Disorder
The goal of this clinical trial is to examine the effect of Tidal Model-based psychiatric nursing approach on internalized stigma and psychological well-being in mothers of children diagnosed with ASD.
- Trial name
- NCT05871931
- Testing
- Tidal Model-based psychiatric nursing approach
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Mersin University
Developmental Disability, Developmental Dyslexia
Postural Control, Grip Strength and Body Posture in Children With Intellectual Disability and Dyslexia
This study investigates physical changes in children with Dyslexia and Intellectual Disability. Participants divided into three groups and Body Posture, Postural Control and Hand Grip Strengths was evaluated.
- Conditions
- Developmental Disability, Developmental Dyslexia, Intellectual Disability
- Trial name
- NCT04250701
- Testing
- Body Posture Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Ahmet Emir
Iron Deficiency Anemia, Neurodevelopmental Abnormality
RAPIDIRON Trial Follow-up Study: RAPIDIRON-KIDS Study
As a follow-up to the RAPIDIRON Trial (NCT05358509), this study will follow the previously randomized mothers as well as their offspring after birth to assess neurodevelopmental, hematologic, and health outcomes.
- Conditions
- Iron Deficiency Anemia, Neurodevelopmental Abnormality, Autism Spectrum Disorder
- Trial name
- RAPIDIRON-KIDS (NCT05504863)
- Testing
- Ferric carboxymaltose, Iron isomaltoside, Ferric Sulfate
- Where
- 3 sites in India
- Volunteers
- 538 people
- Sponsor
- Thomas Jefferson University
Autism Spectrum Disorder
ACT Combined Yoga for Parental Burnout in Parents with Autistic Children
OBJECTIVE: To explore the intervention effect of ACT combined with a yoga intervention program on parenting burnout in parents with ASD.
- Trial name
- NCT06348992
- Testing
- Acceptance commitment therapy and yoga, Active Comparator: Mental Health Education Group
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Harbin Medical University
Autistic Disorder
Extended Management and Measurement of Autism
This open-label research study will continue to monitor the safety of fluoxetine in children after their completion of a previous double-blind placebo controlled clinical study, with fluoxetine.
- Trial name
- EMMA (NCT00787111)
- Testing
- Fluoxetine (prozac)
- Where
- 13 sites in United States
- Volunteers
- 128 people
- Sponsor
- Neuropharm
Nutrition Disorder, Child, Gross Motor Development Delay
Effect of a Nutritional Support System for Improving Gross Motor Function in Cerebral Palsy
Background: Most patients with cerebral palsy (CP) are dependent on parents due to the spasticity and limitations in their gross motor function.
- Conditions
- Nutrition Disorder, Child, Gross Motor Development Delay, Neuro: Cerebral Palsy, Diet Modification
- Trial name
- ENSSIGMCP (NCT03933709)
- Testing
- Nutritional Support System (NSS), deworming, recommended diet
- Volunteers
- 30 people
- Sponsor
- Anahuac University
Elopement, Autism Spectrum Disorder
A Study of the Elopement Prevention and Safety Training Program
The purpose of this study is to demonstrate the feasibility of the Elopement Prevention Safety (EPST) program in children with autism spectrum disorder (ASD) who have engaged in eloping.
- Trial name
- NCT02383732
- Testing
- Universal Safety Measures Module (All participants), Proximity Training Module (Bolting Prevention Participants), Check-In Training Module (Wandering Prevention Participants)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Emory University
Autism
Study to Evaluate the Efficacy and Safety of Aripiprazole
To evaluate the efficacy of flexibly dosed aripiprazole in reducing serious behavioral problems in Asian children and adolescents with a diagnosis of autism spectrum disorder, as measured by change from baseline to endpoint on…
- Trial name
- NCT02069977
- Testing
- Aripiprazole
- Where
- 6 sites in Philippines, South Korea and 1 more
- Volunteers
- 79 people
- Sponsor
- Yoo-Sook Joung
Child Development Disorder, Post Partum Depression
Optimization of Mother-child Dyad Follow-up by a Multidomain Application: Real-world Cross Sectional Study
After birth, the mother-child dyad can be impacted by issues which are usually under-detected or detected at early stage. Among these issues, neurodevelopmental disorders (NDD) such as autism spectrum disorder are common and…
- Trial name
- MALO_2 (NCT05215028)
- Testing
- web-application
- Where
- France
- Volunteers
- 4,346 people
- Sponsor
- Weprom
Autism Spectrum Disorder
Relationships, Employment, Autonomy, and Life Satisfaction (REALS) Study
One of the major methodological obstacles to more informed policies and programs to support the successful transition to adulthood in autism spectrum disorder (ASD) is the absence of suitable measures of meaningful outcomes for…
- Trial name
- REALS (NCT04381195)
- Testing
- REALS Development, REALS Testing
- Where
- United States
- Volunteers
- 1,650 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Autism Spectrum Disorder
Promoting Transactional Supports to Optimize Social Communication Outcomes for Infants and Their Families
This early treatment project is designed to address two significant public health challenges - the need for validated, manualized, treatments for young children with Autism Spectrum Disorder (ASD) that are cost-efficient and…
- Trial name
- NCT03307057
- Testing
- Social Communication Growth Charts (SCGC), Parent-Implemented (P-I) Condition, Clinician-Implemented (C-I) Condition
- Where
- United States
- Volunteers
- 269 people
- Sponsor
- Emory University
Cognitive Impairment, Child Autism
Exercise and Cognition in Children With ASD
Physical exercise is widely reported to be beneficial to executive functions (EFs) in children with autism spectrum disorder (ASD).
- Trial name
- NCT05503459
- Testing
- Bicycle learning, Stationary cycling
- Where
- Hong Kong
- Volunteers
- 82 people
- Sponsor
- Education University of Hong Kong
Autism
To Share or Not To Share: Navigating Disclosure and Stigma Among Family Caregivers of Autistic Young Adults_Group Intervention
This study is a caregiver support program for family caregivers of autistic young adults (ages 18 to 26) as their family members navigate young adulthood.
- Trial name
- NCT07856927
- Testing
- Group Intervention
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Wisconsin, Madison
Autism
Randomized Study of Fluoxetine in Children and Adolescents With Autism
OBJECTIVES: I. Evaluate the efficacy of fluoxetine on social and language deficits, global severity and compulsive dimensions of children and adolescents with autism. II.
- Trial name
- NCT00004486
- Testing
- fluoxetine
- Where
- 3 sites in United States
- Volunteers
- 45 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Pervasive Developmental Disorder
Trial of Low-Dose Naltrexone for Children With Pervasive Developmental Disorder (PDD)
This study will examine the effects of low-dose naltrexone (LDN) on children with autistic spectrum disorders. The investigators hope to show a positive effect on social functioning and language.
- Trial name
- NCT00318162
- Testing
- low dose naltrexone
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Hadassah Medical Organization
Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder
SKOLKONTAKT - Social Skills Training in a School Setting
The study investigates the behavioral effects of an adapted manual-based social skills training program (SKOLKONTAKT) for the mainstream education plan delivered by school personnel, with pupils (15-20 years) with…
- Conditions
- Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder, Anxiety, Depression
- Trial name
- SKOLKONTAKT (NCT04302818)
- Testing
- SKOLKONTAKT, Social activity group
- Where
- Sweden
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Anemia, Inflammation
Acute vs. Delayed Iron Therapy: Effect on Iron Status, Anemia and Cognition
The research questions to be answered by this study are: 1. Is treatment with iron more effective at improving anemia if given at the time of a malaria episode or 1 month after the episode? 2.
- Conditions
- Anemia, Inflammation, Malaria Morbidity, Cognitive Development
- Trial name
- NCT01093989
- Testing
- Ferrous Sulphate Syrup
- Where
- Uganda
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Developmental Disabilities, Sleep Disorders
Use of an Educational Story to Prepare Children With Developmental Disabilities for Sleep Study
The investigators hypothesize that use of an educational story with pictures illustrating overnight sleep study procedure (also called polysomnography or PSG)accompanied by simple narrative will be a cost-effective, readily…
- Conditions
- Developmental Disabilities, Sleep Disorders, Polysomnography, Preparation for Medical Procedure
- Trial name
- NCT02132273
- Testing
- Educational Story
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Jennifer Accardo
Autism Spectrum Disorders, Autism
Identification of Characteristics Associated With Symptom Remission in Autism
Autism is defined as a lifelong pervasive developmental disability, as such, symptom recovery is considered rare. Reports by Lovaas and McEachin, Smith \& Lovaas and more recently by Cohen, Amerine-Dickens, \& Smith, Smith Groen…
- Trial name
- NCT00938054
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)