Clinical trials: Developmental Language Disorder and Language Impairment
Autism Spectrum Disorder
Leucovorin for the Treatment of Language Impairment in Children With Autism Spectrum Disorder
The purpose of this study is to determine the effectiveness of folinic acid in the treatment of language problems in children with autism spectrum disorder. Folinic acid, also known as leucovorin, is approved by the U.S.
- Trial name
- NCT02839915
- Testing
- Folinic Acid
- Where
- 4 sites in United States
- Volunteers
- 56 people
- Sponsor
- Southwest Autism Research & Resource Center
Developmental Delays
Empower EI: Comparing Early Intervention Approaches to Improve Communication in Toddlers With Developmental Delays
This study is testing three ways to deliver Early Intervention (EI) services for toddlers with developmental disabilities (DD). Children enrolled in EI speech therapy will receive one of three approaches: 1.
- Trial name
- NCT07227974
- Testing
- Therapist-Delivered Early Intervention Approach, Caregiver Coaching Early Intervention Approach, Parents Taking Action
- Where
- United States
- Volunteers
- 1,269 people
- Sponsor
- Northwestern University
Developmental Dyslexia
Comparing the Efficacy of tDCS and tRNS to Improve Reading Skills in Children and Adolescents With Dyslexia
The present study grounds on the absence of evidence-based treatment in individuals with developmental dyslexia (DD). At this topic, the present study will explore the potential effect of transcranial random noise stimulation…
- Trial name
- NCT05832060
- Testing
- Active tDCS, Active tRNS
- Where
- Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bambino Gesù Hospital and Research Institute
Persistent Developmental Stutter, Childhood-Onset Fluency Disorder (Stuttering)
Stimulation of the Thalamus to Ameliorate Persistent Disfluency
Persistent developmental stutter / childhood onset fluency disorder is a disabling condition leading to significant communication and psychological disability.
- Trial name
- SToPeD (NCT05641701)
- Testing
- System On, System off
- Volunteers
- 3 people
- Sponsor
- University of British Columbia
Premature Baby, Neurocognition, Child
Longitudinal Assessment of Early Premature Infant Skills for Audiovisual Speech Perception
From birth, babies perceive speech face to face with their interlocutors in audiovisual situations (AV): in addition to hearing them (auditory speech), they will also, in most cases, be able to observe their speaking faces (ex…
- Trial name
- Pré-AV (NCT07245693)
- Testing
- Audiovisual association capability tests
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Grenoble
Language Development, Language Development Disorders
Efficacy of an Early Rhythmic Intervention in Infancy
The present project develops from a wide research line aiming at identifying very early electrophysiological risk markers for neurodevelopmental disorders.
- Conditions
- Language Development, Language Development Disorders, Infant Development, Intervention
- Trial name
- NCT04755309
- Testing
- Rhythmic intervention, Passive auditory stimulation
- Where
- Italy
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Reading Disorder, Developmental
Camp SMART Speech to Print Summer Literacy Camp
This project aims to explore the feasibility and efficacy of a 6-week, intensive summer literacy intervention provided to children in 1st-3rd grades.
- Trial name
- NCT06442098
- Testing
- CAMP SMART Literacy Summer Camp
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- San Diego State University
Developmental Language Disorder and Language Impairment
Recasting or Book Reading by Parents or Clinicians
Developmental Language Disorder (DLD) affects approximately seven percent of the population and is characterized by grammatical deficits that cascade into lifelong academic challenges and under-employment.
- Trial name
- NCT05099328
- Testing
- Recast Therapy, Syntax Stories
- Where
- 2 sites in United States
- Volunteers
- 137 people
- Sponsor
- University of Delaware
Stuttering, Fluency Disorders
Enhancing Speech Fluency With Non-invasive Brain Stimulation in Developmental Stuttering
This study aims to test whether the addition of transcranial direct current stimulation (TDCS) to speech fluency training results in improvements in speech fluency in adults with developmental stuttering.
- Conditions
- Stuttering, Fluency Disorders, Speech Disorders
- Trial name
- NCT02288598
- Testing
- Anodal TDCS, Fluency Training
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Oxford
Speech Disorders in Children
Infant Feeding, Non-nutritive Sucking and Speech Development
This study will look at whether there is a relationship between how babies are fed, whether they suck a dummy/hand and how they develop speech.
- Trial name
- NCT03315416
- Testing
- Speech Sound Assessment
- Where
- United Kingdom
- Volunteers
- 135 people
- Sponsor
- Samanth Burr
Language Development Disorders
EMT en Español for Spanish-speaking Toddlers With Language Delays
The goal of the study is to conduct an initial efficacy study of a promising therapist and caregiver-implemented communication intervention to improve language and school readiness skills in low-income Spanish-speaking children…
- Trial name
- NCT04066049
- Testing
- EMT en Español
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Developmental Language Disorders
Treating Complex Grammar Knowledge Deficits in School-Age Children With Developmental Language Disorder
The goal of this project is to compare the relative effectiveness of two novel treatments to improve the complex grammar knowledge of school-age (8-11-year-old) children with developmental language disorder (DLD).
- Trial name
- DLD Treatment (NCT06911138)
- Testing
- Behavorial
- Where
- 4 sites in United States
- Volunteers
- 150 people
- Sponsor
- Ohio University
Dementia (Diagnosis), Alzheimer Dementia (AD)
Speech-Based Artificial Intelligence for Detection of Dementia in Danish Patients (DetectAI)
The goal of this observational study is to learn if an artificial intelligence (AI)-based speech analysis tool can identify which patients with memory problems need specialist evaluation at a memory clinic.
- Conditions
- Dementia (Diagnosis), Alzheimer Dementia (AD), Vascular Dementia (VaD), Lewy Body Dementia (LBD)
- Trial name
- DetectAI (NCT07200739)
- Testing
- Mini-mental State Examination, Addenbrooke's Cognitive Examination, Speech Task - Picture Description
- Where
- Denmark
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Language Development Disorders
Memorisation of Phonologic Information Among Children With Oral Language Developement Disorder
The disorder of oral language development is defined by the delay in language acquisition in children who possess efficient auditory acuity and normal non verbal intellect.
- Trial name
- MEMENTO (NCT02609542)
- Testing
- Eye Tracking
- Where
- France
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Lille Catholic University
Language Development Disorders
Addressing Treatment Nonresponders
The goal of this clinical trial is to see if providing late talking toddlers who are not responding to the Vocabulary Acquisition and Usage for Late Talkers (VAULT) treatment with a different way of communicating will help them…
- Trial name
- NCT05921227
- Testing
- VAULT Phase 6
- Volunteers
- 16 people
- Sponsor
- University of Arizona
Down Syndrome
Augmentative and Alternative Communication (AAC) and Lexical Gain in Children With Down Syndrome
Children with Down syndrome (DS) have language development particularities that have negative effects in the communication capacity. By this way, Augmentative and Alternative Communication (AAC) is indicated to this population.
- Trial name
- NCT00689988
- Testing
- speech-language therapy with AAC intervention
- Where
- Brazil
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Developmental Dyslexia
Assessing the Generalizability of the Tachidino Protocol to Different Clinical Contexts
The study aims to document the effectiveness and acceptability of the intervention system for specific reading and writing disorders, in use at Scientific Institute (IRCCS) Medea, as applied and adapted to a different clinical…
- Trial name
- NCT04384718
- Where
- 3 sites in Italy
- Volunteers
- 32 people
- Sponsor
- IRCCS Eugenio Medea