Clinical trials: Developmental Risk
Obesity, Diabetes
Role of Nutrition and Maternal Genetics on the Programming of Development of Fetal Adipose Tissue
In the PREOBE projects it is aimed to obtain genetic and biochemical biomarkers for the programming of obesity in early stages of life.
- Trial name
- PREOBE (NCT01634464)
- Where
- Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Cardiac Disease, Ventricular Arrythmia
Development of an Artificial Intelligence Algorithm to Detect Pathological Repolarization Disorders on the ECG and the Risk of Ventricular Arrhythmias
Torsades de Pointes (TdP) are potentially fatal ventricular arrhythmias that are promoted by prolonged ventricular repolarization (Long QT, LQT).
- Trial name
- DEEPECG4U (NCT05829993)
- Where
- France
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Infant Development, Infant,Premature
Pacifier Activated Device and Mother's Voice in Infants at High-risk for Cerebral Palsy
The study seeks to determine the efficacy of non-nutritive suck (NNS) training using a pacifier-activated device (PAM) with mothers' voice to condition suck-strength and rhythmicity, in improving the feeding and developmental…
- Conditions
- Infant Development, Infant,Premature, Hydrocephalus, Neonatal Encephalopathy
- Trial name
- NCT03230032
- Testing
- pacifier-activated device
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
Breastfeeding, Dietary Intake
NUTRIPROTECT-Children Nutrition as a Protective or Health-risk Factor
Despite the intensive worldwide research dedicated to the nutrition and faecal microbiota, the studies that follow the link between the early nutrition, initial intestinal microbiota, and development of children over a longer…
- Conditions
- Breastfeeding, Dietary Intake, Health, Body Composition
- Trial name
- My-Milk-2 (NCT04076592)
- Where
- Slovenia
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- University of Ljubljana
Burnout, Sleep Disturbance
Non-Invasive Sleep Monitoring for Burnout and Retention Risk in Postgraduate Nurses
Newly graduated nurses often experience high levels of psychological stress, sleep disturbance, fatigue, and burnout during the early transition into clinical practice.
- Conditions
- Burnout, Sleep Disturbance, Occupational Stress, Mental Health
- Trial name
- NCT07666633
- Testing
- Non-Invasive Sleep Monitoring
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Armed Forces General Hospital
Adolescent Development
Evaluation of Yoga for Substance Use Risk Factors in a School Setting
This study will evaluate the efficacy of yoga taught during school to positively influence risk and protective factors of substance use and the initiation and severity of substance use.
- Trial name
- NCT01821950
- Testing
- Yoga during physical education
- Where
- United States
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Asthma
Airway Inflammation in Swimmers
Studies have shown that the prevalence of respiratory symptoms, airway hyperresponsiveness (AHR) and asthma is high and increasing in elite athletes.
- Trial name
- NCT00207038
- Where
- Denmark
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Postpartum Depression
Postpartum Anemia and Postpartum Depression
Postpartum anemia (PPA) and Postpartum depression (PPD) are common afflictions affecting women after childbirth. Both disorders have a significant impact on women's health and functional status.
- Trial name
- PPADS (NCT00782912)
- Where
- Canada
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Pregnancy Related, Pregnancy Disease
Chinese Pregnant Woman Cohort Study (Offspring Follow-up)
Purpose: To investigate the growth and development status for children of 1 ~ 3 years old in China, and to explore and analyze the influencing factors of infant growth.
- Conditions
- Pregnancy Related, Pregnancy Disease, Pregnancy, Infant Development
- Trial name
- NCT04444791
- Where
- China
- Volunteers
- 1,978 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College
Predictive Cancer Model
Innovative Approach to Detect Recurrent Colorectal Lesions With Surveillance Via Mutation Analysis & Clinical Phenotype
It is known that the development of colorectal adenoma is dependent on the appearance of somatic mutations in protooncogenes and tumor suppressor genes.
- Trial name
- MTG (NCT05929365)
- Testing
- colonoscopy
- Where
- Czechia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Military University Hospital, Prague
Cardiovascular Diseases
Development of CV Risk Prediction Tools Based on AI and Fundus Imaging Technology Study (PERFECT)
This study aims to develop a cardiovascular disease (CVD) screening tool and cardiovascular risk prediction tool based on fundus imaging data with the method of artificial intelligence.
- Trial name
- PERFECT (NCT06181552)
- Testing
- fundus photograpgy, optical coherence tomography, optical coherence tomography angiography
- Volunteers
- 1,072 people, healthy volunteers welcome
- Sponsor
- China National Center for Cardiovascular Diseases
Preterm Birth, Parent-Child Relations
Epigenetics and Protective Factors in the Preterm Infant
Preterm infants (PT) spend their first weeks of life in the Neonatal Intensive Care Unit (NICU) where they are exposed to unfavorable conditions with different effects on child development including long-term alterations in…
- Conditions
- Preterm Birth, Parent-Child Relations, Epigenetics
- Trial name
- EPIC (NCT04804280)
- Testing
- DNA methylation of target genes, Functional Magnetic Resonance Imaging (fMRI) acquisition
- Where
- Italy
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Infant Development, Cerebral Palsy
Families Filming Infants Learning Movement
The study objective is to improve accuracy in the early detection of neurodevelopmental impairment, especially CP, by evaluating the timepoint (in weeks post term age) that the Prechtl GMA is most useful for prediction of…
- Conditions
- Infant Development, Cerebral Palsy, Motor Disorders, Neurological Disorder
- Trial name
- FILM (NCT06278961)
- Testing
- Observational
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Autism Spectrum Disorder (ASD), Neurodevelopmental Disorders
Multi-observational Study for the Early Identification of Autism Spectrum Disorder (ASD) and Other Neurodevelopmental Disorders (NDD) in At-risk Populations
Autism spectrum disorder (ASD) is a neurodevelopmental disorder (NDD) that affects about 78 million people worldwide. Its prevalence and degree of impact on individuals and families place it among disorders of global importance.
- Trial name
- BABY@NET (NCT06915805)
- Where
- 5 sites in Italy
- Volunteers
- 296 people, healthy volunteers welcome
- Sponsor
- Istituto Superiore di Sanità