Clinical trials: Diabete Type 1
Diabetes Mellitus, Type 1
AHCL System Initiation in T1D Patients naïve to Technology
The primary objective of this study is to evaluate whether the MiniMed 780G AHCL system improves glycemic control and Quality of Life (QoL) perception in adult individuals with T1D and naïve to CSII and CGM technologies.
- Trial name
- NCT04616391
- Testing
- insulin pump Medtronic 780G
- Volunteers
- 40 people
- Sponsor
- Jagiellonian University
Diabetes in Children, Diabetes Type 1
Intelligent Care Platform - Quasi-Experimental Trial
This study will measure the implementation and effectiveness of an intervention, the use of a digital health tool, Haibu Diabetes, for the management of pediatric type 1 diabetes (T1D), on clinical outcomes.
- Trial name
- UBColumbia (NCT07712809)
- Testing
- Digital Diabetes Care Platform
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- University of British Columbia
Diabetes Mellitus, Diabetes Mellitus ( Type 1 and Type 2)
PMCF Study of GX-01S CGM in Adults With Diabetes
This clinical study evaluates the GX-01S Continuous Glucose Monitoring (CGM) System in adults with Type 1 or Type 2 diabetes. CGM systems measure glucose levels continuously throughout the day, providing real-time information…
- Trial name
- PROMISE-GX (NCT07802327)
- Testing
- GX-01S Continuous Glucose Monitoring System
- Volunteers
- 100 people
- Sponsor
- MicroTech Medical（Hangzhou）Co.,Ltd.
Quality of Life, Burden, Dependency
Impact of the Use of a Closed-loop Insulin Therapy on the Burden of the Diabetes and the Quality of Life
The use by diabetes patients of real-time Continuous Glucose Monitoring (CGM) system is becoming widespread and has changed diabetic practice. Automated closed-loop (CL) insulin therapy has come of age.
- Trial name
- IMPLIQUE (NCT04939766)
- Testing
- Activation of a closed loop device in an insulin pump device with GCM
- Volunteers
- 250 people
- Sponsor
- VitalAire
Diabetes Mellitus, Type 1
GAD-Alum (Diamyd) Administered Into Lymph Nodes in Combination With Vitamin D in Type 1 Diabetes (DIAGNODE-1)
The objectives of the main study is to: Evaluate the safety of giving GAD-Alum (Glutamic acid decarboxylase) (Diamyd) directly into lymph glands in combination with an oral vitamin D regimen Evaluate how the above mentioned…
- Trial name
- DIAGNODE (NCT02352974)
- Testing
- GAD-Alum, Vitamin D
- Where
- Sweden
- Volunteers
- 12 people
- Sponsor
- Johnny Ludvigsson
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Inhaled Technosphere Insulin in Subjects With Diabetes Mellitus and Asthma
The clinical trial is designed to evaluate the safety of inhaled Technosphere/Insulin compared with non-inhaled anti-diabetic therapies in subjects with type 1 or type 2 diabetes mellitus and concurrent asthma.
- Conditions
- Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Asthma
- Trial name
- NCT00332826
- Testing
- Technosphere Insulin
- Where
- 78 sites in United States, Argentina and 9 more
- Volunteers
- 3 people
- Sponsor
- Mannkind Corporation
Diabetes Type 1, Proteomics
Proteomic Analysis in Paediatric Diabetes Type 1 (PAPD)
The aim of the present study is to investigate a targeted proteomic analysis in plasma of children - of Greek origin- with type 1 diabetes (DT1) and its correlation with the electrophysiological findings that accompany diabetic…
- Conditions
- Diabetes Type 1, Proteomics, Diabetic Peripheral Neuropathy
- Trial name
- PAPD (NCT04257877)
- Testing
- Blood sampling
- Where
- Greece
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Diabetes Mellitus, Type 1
DIABGAD - Trial to Preserve Insulin Secretion in Type 1 Diabetes Using GAD-Alum (Diamyd) in Combination With Vitamin D and Ibuprofen
The objectives of this study is to evaluate the safety and influence of treatment with GAD-Alum (Diamyd) combined with Vitamin D and Ibuprofen on preservation of residual insulin secretion in recently diagnosed Type 1 Diabetes…
- Trial name
- NCT01785108
- Testing
- GAD-Alum (Diamyd) 20 µg, GAD-Alum (Diamyd) 20 µg X 2, Vitamin D
- Where
- 10 sites in Sweden
- Volunteers
- 60 people
- Sponsor
- Johnny Ludvigsson
Diabetes Type 1
InPen User Experience
The purpose of this study is to evaluate the user experience of InPen™ with InPen™ Diabetes Management App and Guardian 4 system in adult patients with type 1 diabetes for the design of a future pivotal study.
- Trial name
- NCT05029271
- Testing
- InPen with Guardian 4 System
- Where
- 3 sites in Sweden
- Volunteers
- 34 people
- Sponsor
- Medtronic MiniMed, Inc.
Diabetes Type 1
Insul-In This Together: Leveraging Family Support and Diabetes Technology for Adolescents Living With Type 1 Diabetes
The goal of this clinical trial is to learn if the "Insul-In This Together" family program works to improve outcomes for adolescents living with type 1 diabetes.
- Trial name
- IITT (NCT07856836)
- Testing
- Insul-In This Together
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Stanford University
Type 1 Diabetes
Incretin Effect on the Immunological Phenotype
Assessment of the effect of incretin based therapies (Liraglutide and Saxagliptin) on immune cells in healthy subjects and patients with type 1 diabetes
- Trial name
- NCT01782261
- Testing
- Liraglutide, Saxagliptin
- Where
- Austria
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Diabetes Mellitus, Type 1
Gan & Lee Insulin Glargine Target Type (1) Evaluating Research
Primary Objective: •To evaluate equivalence of Gan \& Lee Insulin Glargine Injection and Lantus® in terms of immunogenicity Secondary Objective: Immunogenicity: To evaluate the percentage of subjects with negative anti-insulin…
- Trial name
- GLITTER1 (NCT03371082)
- Testing
- Gan & Lee Insulin Glargine Injection, Lantus®
- Where
- 85 sites in United States, Czechia and 4 more
- Volunteers
- 576 people
- Sponsor
- Gan and Lee Pharmaceuticals, USA
Diabete Type 1, Diabete Type 2
VOIES-D-ql - Qualitative Study on Experiences of Diabetes Care Delivery and Planning
Population aging and the increase in incidence and prevalence of potentially disabling chronic conditions make health care more and more complex and costly.
- Trial name
- VOIES-D-ql (NCT04217902)
- Testing
- Description of patients' experiences of diabetes care delivery and planning, Description of health care professionals needs and experiences in diabetes care delivery and planning
- Where
- France
- Volunteers
- 33 people
- Sponsor
- Hospices Civils de Lyon
Diabetes Type II
Novel Biomarker for Development of T2D
The investigators wants to determine if 11β-HSD1 activity will be positively associated, and 5α-reductase activity negatively associated, with (a) degree of insulin resistance defined by the homeostatic model assessment of…
- Trial name
- NCT02326129
- Where
- 3 sites in United States
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Duke University
Non-Proliferative Diabetic Retinopathy, Cataract
Nepafenac Once Daily for Macular Edema - Study 2
The purpose of this study is to demonstrate superiority of Nepafenac Ophthalmic Suspension, 0.3% dosed once daily relative to Nepafenac Vehicle based upon clinical outcomes among diabetic participants following cataract surgery.
- Trial name
- NCT01872611
- Testing
- Nepafenac Ophthalmic Suspension, 0.3%, Vehicle, Prednisolone acetate
- Volunteers
- 819 people
- Sponsor
- Alcon Research
Diabete Type 1, Diabetes in Children
Buzzy and TickleFlex in Reducing Insulin Injection Pain and Fear
This interventional randomized controlled clinical trial aims to evaluate the effectiveness of two nonpharmacological devices, Buzzy and TickleFlex, in reducing pain and fear associated with insulin injections among children with…
- Trial name
- NCT07239700
- Testing
- Buzzy, TickleFlex, None (Routine Care)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Hakkari Universitesi
Macular Edema, Diabetes Mellitus
Laser and Antioxidant Treatment of Diabetic Macular Edema
This study will compare the side effects of two laser treatments for diabetic macular edema, a common condition in patients with diabetes.
- Trial name
- NCT00055042
- Testing
- Vitamin E
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- National Eye Institute (NEI)
Diabetes, Type 1, Diabetes, Type 2
Safety of Inhaled Insulin With Type 1 and Type 2 Diabetes
Pulmonary Safety in Diabetics with T/I
- Trial name
- NCT00308737
- Testing
- Technosphere® Insulin Inhalation Powder, Usual Care
- Where
- 176 sites in United States, Canada and 6 more
- Volunteers
- 2,053 people, healthy volunteers welcome
- Sponsor
- Mannkind Corporation
Diabetes, Hypoglycemia
A Study to Improve Diabetes Management Among Adults Experiencing Severe Hypoglycemia
This pilot study will assess the feasibility, preliminary efficacy, and acceptability of the Diabetes-REM (Rescue, Engagement, and Management), a comprehensive patient-centered intervention delivered by community paramedics in…
- Conditions
- Diabetes, Hypoglycemia, Diabetes Type 1, Diabetes Type 2
- Trial name
- NCT04874532
- Testing
- Community Paramedic Program, Education Material
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Mayo Clinic
Diabetes Type 1
Inpatient Evaluation of the MD-Logic Artificial Pancreas System in Patients With Type 1 Diabetes
The purpose of this feasibility study is to evaluate the MDLAP (MD-Logic Artificial Pancreas system)automated insulin management system using continuous glucose monitoring (CGM) and subcutaneous insulin pump infusion in…
- Trial name
- MD-Logic- Cont (NCT01501032)
- Testing
- MD-logic artificial pancreas system
- Where
- Israel
- Sponsor
- Rabin Medical Center