Clinical trials: Diabetes, Type 1
Type 1 Diabetes
Omnipod 5 System Compared to Pump Therapy
Subject will undergo a 14-day outpatient, standard therapy phase during which sensor and insulin data will be collected. This will be followed by a 90-day outpatient phase where subjects will either use the Omnipod 5 system or…
- Trial name
- NCT05409131
- Testing
- Omnipod 5 System
- Where
- 14 sites in United States, France
- Volunteers
- 196 people
- Sponsor
- Insulet Corporation
Diabetes, Diabetes Mellitus, Type 1
Observational Study to Evaluate the Safety of Levemir® in Diabetes
This observational study is conducted in North America. The aim of this observational study is to evaluate the incidence of adverse events while using Levemir® under normal clinical practice conditions.
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- PREDICTIVE™ (NCT00706017)
- Testing
- insulin detemir
- Where
- Mexico
- Volunteers
- 2,282 people
- Sponsor
- Novo Nordisk A/S
Type 1 Diabetes
Liraglutide in Type 1 Diabetes
The glucose lowering effects of GLP-1 agonists are well established in subjects with type 2 diabetes, however, these have not been studied prospectively in subjects with type 1 diabetes.
- Trial name
- 1966 (NCT01722240)
- Testing
- Liraglutide 1.8mg
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University at Buffalo
Macrosomia, Induction of Labour
Induction of Labour for LGA fœtus in Women Without Insulin-treated Diabetes.
A french study published in 2015 (DAME) showed a decrease of shoulder dystocia and an increase of spontaneous vaginal delivery when the non insulin-treated diabetes patients with large-for-date fetus were induced.
- Conditions
- Macrosomia, Induction of Labour, Non-insulin-dependent Diabetes
- Trial name
- NCT03355040
- Testing
- induction of labour
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Montpellier
Diabetes Mellitus, Type 1
Non-compliance on Treatment Among Diabetic Students at Sohag University
A cross-sectional study on diabetic students in Sohag University will be conducted to collect data about factors affecting compliance and adherence to diabetes treatment and its impact on development of complications.
- Trial name
- NCT05286450
- Where
- Egypt
- Volunteers
- 153 people
- Sponsor
- Sohag University
Type 1 Diabetes, Peripheral Arterial Calcification
Impact of Metformin on Peripheral Arterial Calcification in Type 1 Diabetes
Vascular calcification (VC) is a complication frequently observed in elderly, in chronic kidney disease (CKD) and in diabetes (particularly in type 1 diabetes).
- Trial name
- IMPACT-1D (NCT04583462)
- Testing
- Metformin
- Where
- France
- Volunteers
- 230 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Type 1 Diabetes Mellitus
CoYoT1 to California
CoYoT1 to California (CTC) was initiated to develop a patient-centered, home telehealth care model for young adults (YA) ages 16-25 with T1D. It is a 2x2 factorial design, 15-month intervention.
- Trial name
- CTC (NCT03793673)
- Testing
- CoYoT1 Care, Standard Care
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Children's Hospital Los Angeles
Diabetes Mellitus, Type 1
Optimizing Closed-Loop Control of Type 1 Diabetes Mellitus in Adolescents
The purpose of this study is to use a closed-loop Control-to-Range (CTR) system in adolescents with type 1 diabetes in an outpatient setting, and to evaluate the CTR system's ability to significantly improve blood glucose levels…
- Trial name
- NCT01890954
- Testing
- Diabetes Assistant (DiAs)
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Virginia
Type1diabetes, Metabolic Syndrome
The Effect of Exercise on Metabolic Parameters, Anthropometric Measurement Values and Quality of Life
This study was planned as a randomized controlled experimental study to determine the effect of exercise with Augmented Reality Glasses (AR) on metabolic parameters, anthropometric measurement values and quality of life in…
- Conditions
- Type1diabetes, Metabolic Syndrome, Nursing Caries
- Trial name
- NCT05737654
- Testing
- Exercise with augmented reality glasses
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- TC Erciyes University
Diabetes Mellitus
Evaluation of the Accuracy of an Implanted Glucose Sensor
The purpose of this clinical investigation is to evaluate the accuracy of the Senseonics Continuous Glucose Monitoring System (Senseonics CGM System) measurements when compared with reference standard measurements The…
- Trial name
- PRECISEII (NCT02647905)
- Testing
- Continuous Glucose Monitoring System
- Where
- 9 sites in United States
- Volunteers
- 90 people
- Sponsor
- Senseonics, Inc.
Hypoglycemia, Diabetes Mellitus, Type 1
The Late Effects of Ethanol Intake on the Glucose Response to Subcutaneous Glucagon in Type 1 Diabetes
Objective: Because many people with type 1 diabetes drink ethanol and because glucagon is used to treat mild hypoglycaemia, it is essential to determine whether ethanol will impair the effectiveness of glucagon to increase…
- Trial name
- ALCO1 (NCT02881060)
- Testing
- Alcohol
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Hvidovre University Hospital
Diabetes Mellitus Type I, Diabetes Mellitus Type II
Collection of Performance Data From the Integrated Sensor and Infusion Set. TRIAL 4
This is a multi-center, non-randomized, and interventional study in which subjects will use the Integrated sensor and infusion set with MiniLink Transmitter and the Medtronic Paradigm® VEO™ insulin pump (Sensor augmented pump)…
- Trial name
- NCT01775059
- Testing
- Integrated sensor and infusion set.
- Where
- 3 sites in Denmark
- Volunteers
- 50 people
- Sponsor
- Medtronic Diabetes R&D Denmark
Diabetes Mellitus, Type 1
Evaluation of Minimed 670G in T1D Patients on Multiple Daily Injection
Introduction. Sensor Augmented Pump has demonstrated superiority over insulin pump and Multiple Daily Injection (MDI) in achieving optimal glucose control and can improve quality of life in Type 1 Diabetes (T1D) patients.
- Trial name
- NCT03755479
- Testing
- Hybrid Closed Loop Insulin Pump Minimed 670G
- Where
- Qatar
- Volunteers
- 30 people
- Sponsor
- Sidra Medicine
Type 1 Diabetes
Safety Evaluation of the Hybrid Closed Loop (HCL) System in Pediatric Subjects With Type 1 Diabetes
This study is a single-arm, multi-center, Home and Hotel Clinical Investigation in pediatric subjects with type 1 diabetes on insulin pump therapy.
- Trial name
- NCT02660827
- Testing
- Insulin Pump
- Where
- 11 sites in United States, Israel
- Volunteers
- 151 people
- Sponsor
- Medtronic MiniMed, Inc.
Type 1 Diabetes Mellitus
Glucagon Counterregulation in Type 1 Diabetes
The purpose of this study is to find out whether the combination of insulin and pramlintide is better than insulin alone at helping the pancreas release glucagon in response to a low blood sugar episode.
- Trial name
- NCT03547427
- Testing
- Basal insulin alone, Basal pramlintide and reduced basal insulin, CGM
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Virginia
Diabetes Mellitus, Diabetes Mellitus ( Type 1 and Type 2)
PMCF Study of GX-01S CGM in Adults With Diabetes
This clinical study evaluates the GX-01S Continuous Glucose Monitoring (CGM) System in adults with Type 1 or Type 2 diabetes. CGM systems measure glucose levels continuously throughout the day, providing real-time information…
- Trial name
- PROMISE-GX (NCT07802327)
- Testing
- GX-01S Continuous Glucose Monitoring System
- Volunteers
- 100 people
- Sponsor
- MicroTech Medical（Hangzhou）Co.,Ltd.
Type 1 Diabetes
Polyphenol Enriched Extra-virgin Olive Oil and Postprandial Glycemia in Type 1 Diabetes (DOP)
The aims of this study are to investigate the short term effects of MUFA alone vs. MUFA plus Polyphenols contained in the extra-virgin olive oil (EVOO) on the postprandial glycemic response in patients with type 1 diabetes and to…
- Trial name
- DOP (NCT04764786)
- Testing
- EVOO+POLY, OO-POLY
- Where
- Italy
- Volunteers
- 22 people
- Sponsor
- Federico II University
Type 1 Diabetes
A Single Bolus, 12-hour Euglycemic Clamp Study of the Safety, Pharmacokinetics (PK) and Glucodynamics (GD) of Intraperitoneal (IP) Portal Insulin U-500
The goal of this clinical trial is to assess the safety of a new U500 insulin formulation and to determine how rapidly it is absorbed and how long it takes to act when administered intraperitoneally.
- Trial name
- NCT07341373
- Testing
- Portal Insulin U-500, Humulin R U-500, Lyumjev U-100 Insulin
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Portal Diabetes, Inc.
Acromegaly, Type 2 Diabetes Mellitus
Growth Hormone Feedback to Insulin-like Growth Factor-I (IGF-1) and Oral Glucose Tolerance Test (OGTT)
Growth hormone (GH) and Insulin-like growth factor-I (IGF-I) secretion are altered in acromegaly and type 2 Diabetes Mellitis (DM).
- Trial name
- NCT00915954
- Testing
- Oral Glucose Tolerance Test, Subcutaneous administration of recombinant human IGF-1
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
T1D, Type 1 Diabetes (T1D)
Evaluation of a Biopsychosocial System
The goal of this observational study is to evaluate the feasibility of a biopsychosocial sensing system integrated into the Adhera Caring Digital Program® for caregivers of children with type 1 diabetes (T1D).
- Conditions
- T1D, Type 1 Diabetes (T1D), Type 1 Diabetes
- Trial name
- NCT07440108
- Testing
- Use of Biopsychosocial Sensing System
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Adhera Health, Inc.