Clinical trials: Diabetes, Type II
Type 2 Diabetes
The Pharmacokinetics Study of Single and Multiple Dose of SP2086 in Healthy Volunteers
SP2086 is a novel inhibitor of Dipeptide base peptidase 4, allows an insulin-independent approach to improve type 2 diabetes hyperglycemia.
- Trial name
- NCT02826044
- Testing
- SP2086
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Diabetes Mellitus, Type 2
Mobile Application for Self-Management of Type 2 Diabetes Mellitus
The goal of this Randomized Controlled Trial is to study the effect of mobile Application on glycemic control of type2 diabetes mellitus.
- Trial name
- NCT06176703
- Testing
- mobile application
- Where
- Thailand
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Ramathibodi Hospital
Diabetes Mellitus, Type 2
A Single-dose Phase 1 Study of DBPR108 in Healthy Male Subjects
The study is being performed to assess the safety, tolerability, and pharmacokinetic (PK) and pharmacodynamic (PD) properties of single oral doses of DBPR108 in healthy male subjects.
- Trial name
- NCT01650324
- Testing
- DBPR108
- Where
- Taiwan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- National Health Research Institutes, Taiwan
Healthy Volunteers, Type 2 Diabetes
A Research Study Comparing Active Drug in the Blood in Healthy Participants Following Dosing of the Current and a New Formulation (C) Semaglutide Tablets
In this study two different tablets for oral use of a known investigational medicinal product, called semaglutide, will be tested.
- Trial name
- NCT04109508
- Testing
- Oral semaglutide
- Where
- Germany
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Cardiovascular Risk Factor, Pre Diabetes
Effects of a Workplace Exercise Intervention on Cardio-Metabolic Health
Background: The rising levels of physical inactivity in the Eastern Mediterranean region (43.2%) and in the United Arab Emirates (38%) compared with the global levels of physical inactivity (31.2%) is alarming (6,15).
- Conditions
- Cardiovascular Risk Factor, Pre Diabetes, High Blood Pressure, Elevated LDL Cholesterol
- Trial name
- NCT04403789
- Testing
- Exercise Time, Supervised Group Exercise
- Where
- United Arab Emirates
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- United Arab Emirates University
Diabetes Mellitus Type 2
Internet Intervention to Improve Rural Diabetes Care
Rural Diabetes Online Care (RDOC) will develop an Internet-based intervention for rural primary care physicians, focusing on improving care for adult patients with diabetes.
- Trial name
- NCT00403091
- Testing
- Internet Intervention, Control
- Where
- 2 sites in United States
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Type 2 Diabetes Mellitus, Pulmonary Function
Lung Function in Patients With Early Type 2 Diabetes Mellitus
To investigate the protective effect of calcium dobesilate, Xuefuzhuyu Decoction, calcium dobesilate combined with Xuefuzhuyu Decoction on the early lung function of type 2 diabetes mellitus
- Trial name
- NCT03167918
- Testing
- Calcium Dobesilate, Xuefuzhuyu Decoction, Xuefuzhuyu Decoction & Calcium dobesilate
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Liaoning University of Traditional Chinese Medicine
Insulin Resistance
Effect of Polyphenol-rich Dark Chocolate on Insulin Sensitivity in Normal Weight and Overweight Adults
The purpose of the study is to determine the effect of polyphenol-rich dark chocolate on insulin sensitivity in normal weight and overweight adults.
- Trial name
- NCT01749020
- Testing
- Polyphenol-rich Dark chocolate
- Where
- United Kingdom
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Queen Margaret University
Obesity, Type 2 Diabetes
Reducing Obesity and Type 2 Diabetes in High Risk Youth
Compare the effect of the HEALT[e]TEEN program and a HEALTH[e]TEEN plus coping skills training delivered to high school students on BMI, nutrition and physical activity behaviors, and self-efficacy over 6 months.
- Trial name
- HEALTH[e]TEEN (NCT01560676)
- Testing
- HEALTH[e]TEEN, HEALTH[e]TEEN + CST
- Where
- United States
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- Yale University
Hypertension, Diabetes
Aliskiren vs Hydrochlorothiazide in Hypertensive Type II Diabetic Patients on Resistance Arteries
This study will be performed only at the Jewish General Hospital. It will investigate the effect of treatment with aliskiren, an inhibitor of renin, a substance produced by the kidney that constricts arteries and raises blood…
- Trial name
- NCT01480791
- Testing
- Aliskiren vs. hydrochlorothiazide, Hydrochlorothiazide
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
Diabetes Mellitus Type 1, Diabetes Mellitus Type 2
Natural History of Autoimmune Diabetes and Its Complications
Background: Diabetes is a disease defined by abnormally high blood sugar (glucose) levels. Glucose is an essential source of energy for the body s cells, but insulin is required to move the glucose into the cells.
- Trial name
- NCT00896610
- Where
- United States
- Volunteers
- 356 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Obesity, Type 2 Diabetes
Hyperbaric Oxygen Therapy and Insulin Resistance (HOTAIR2) - Effect of One HBO Session.
Obesity is an epidemic in Western society and is the biggest risk factor for insulin resistance and type 2 diabetes. The investigators have recently shown that exposure to hyperbaric oxygen (HBO) leads to an increase insulin…
- Trial name
- HOTAIR2 (NCT02009813)
- Testing
- Hyperbaric Oxygen Therapy
- Where
- Australia
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Adelaide
Type 2 Diabetes, Blod Pressure
Vasodilatory and Metabolic Effects of Glucagon-like Peptide-1 in Periphery Circulation in Patients With and Without Type 2 Diabetes Mellitus
Diabetes and high blood pressure are risk factors for developing heart disease. An increase in the number of diabetes patients is expected.
- Conditions
- Type 2 Diabetes, Blod Pressure, Glucagon-like Peptide-1, Human Physiology
- Trial name
- NCT01689051
- Testing
- human glucagon-like peptide 1 (7-36)amide, human glucagon-like peptide 1 (9-36)amide
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Diabetes Mellitus, Type 2, Obesity
Efficacy of mHealth Apps for Health in a Low-income, Type II Diabetic, Hispanic Population
The purpose of this study is to determine the effectiveness of mobile health applications in improving health outcomes and the subsequent benefit of improving type II diabetes outcomes in a low socioeconomic Hispanic population.
- Trial name
- NCT05279729
- Testing
- Mobile health application
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Type 2 Diabetes, Overweight
Effects of Caloric Restriction on Fetuin-A and Cardiovascular Risk Factors
The aim of this randomized controlled study was to evaluate the effects of CR on circulating fetuin-A levels in obese humans with type 2 diabetes based on monitoring energy intake and energy expenditure by daily activity.
- Trial name
- NCT01329822
- Testing
- Caloric restriction
- Where
- South Korea
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Korea University
Diabetes Mellitus, Type 2
Co-ingestion of Rice Bran Soymilk or Plain Soymilk With White Bread: Effects on the Glycaemic and Insulinaemic Response
bread and that rice-bran soymilk will have an additional beneficial effect on the glucose and insulin The proposed research project is important because it will provide, for the first time, evidence on the benefits of the…
- Trial name
- NCT03447080
- Testing
- Control, Ricebran soybean milk, Soybean milk
- Where
- Singapore
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Singapore Institute of Food and Biotechnology Innovation
Diabetes Mellitus, Type 2, Obesity
Fecal Microbiota Transplantation for Diabetes Mellitus Type II in Obese Patients
The incidence of obesity has dramatically increased during the last three decades, leading to a significant increase of obesity-related morbidity, including type 2 diabetes mellitus (T2DM) that is characterized by resistance of…
- Trial name
- NCT02346669
- Testing
- gastroscopy, Fecal Microbiota Transplantation, high fat low fiber diet
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Colorectal Cancer Screening, Diabetes Mellitus, Type 2
Aim 3, Optimizing CRC Screening in Patients With Diabetes in Safety-net Primary Care Settings
This mixed methods study evaluates the effectiveness and feasibility of a multi-level (patient, team, organizations) intervention to optimize CRC screening for patients with diabetes in primary care safety-net settings.
- Trial name
- NCT05785780
- Testing
- Targeted CRC Screening Toolkit
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Diabetes Type 2
Exercise Study on Cardiac Function in Patients With Diabetes Mellitus Type 2 and Diastolic Dysfunction
The aim of the study is to compare the effects of aerobic interval training and the IDF recommendations on physical activity on cardiac function and CV risk factors in patients with diabetes.
- Trial name
- NCT01206725
- Testing
- Exercise
- Where
- Norway
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Sleep, Insulin Resistance
Glucose Metabolism and Sleep in People With Family History of Type 2 Diabetes.
The use of sugar and starch-like foods for energy (carbohydrate metabolism) changes when people sleep. However, it is still not known if differences in the amount of nighttime sleep have an effect on the carbohydrate metabolism…
- Conditions
- Sleep, Insulin Resistance, Type 2 Diabetes
- Trial name
- NCT00720889
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Chicago
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