Clinical trials: Diabetes (DM)
Type 1 Diabetes Mellitus, Chronic Kidney Disease (CKD) With Diabetes Mellitus (DM)
Mitigating DKA in Type 1 Diabetes for Safe Use of SGLT Inhibitors Using Dual Continuous Ketone and Glucose Monitoring.
The goal of this clinical trial is to develop and evaluate a novel diabetes ketoacidosis risk mitigation strategy to support the safe use of sodium-glucose cotransporter-2 inhibitors (SGLT2i) therapy in participants with type 1…
- Conditions
- Type 1 Diabetes Mellitus, Chronic Kidney Disease (CKD) With Diabetes Mellitus (DM), Chronic Kidney Disease, Diabetic Ketoacidosis
- Trial name
- SCOUT-CKD (NCT07325201)
- Testing
- Sotagliflozin initiation
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- HealthPartners Institute
Blood Cholesterol, Blood Pressure Monitoring
Empowering Faith-based Communities to Provide Personalized Diabetes Self-management Education and Support (DSMES) in the Magic City
In this study, individuals living with diabetes in the Birmingham area will participate in a free, 3-month DSMES program hosted by MedsPLUS Consulting, a local independent pharmacy and wellness center, at a local faith-based…
- Conditions
- Blood Cholesterol, Blood Pressure Monitoring, Weight Change, BMI
- Trial name
- MCPILOTDSMES (NCT07556354)
- Testing
- Remote Patient Monitoring in a Faith-Based Program, Traditional Cohort Faith-based DSMES program
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Diabetes (DM), Diabetes Mellitus
Changes in Person-reported Outcomes and Behavior Using the Accu-Chek SmartGuide CGM and Predict App
The goal of this controlled pre-post-trial is to test the Accu-Chek SmartGuide continuous glucose monitoring (CGM) system and whether its predictive features provide additional benefits for adults with type 1 diabetes or insulin…
- Conditions
- Diabetes (DM), Diabetes Mellitus, Diabetes Mellitus Type 2, Diabetes Mellitus Type 1
- Trial name
- NCT07814508
- Testing
- SmartGuide CGM with Predictive Features
- Where
- Germany
- Volunteers
- 89 people
- Sponsor
- FIDAM RDC
Type 2 Diabetes Mellitus (DM)
Tolerability and Safety of Nano-Tocotrienols
The goal of this randomised controlled trial is to determine the long term safety and tolerability of nano-tocotrienols (50 - 400 mg/day for 6-months duration) to be used as a health supplement in both healthy individuals and…
- Trial name
- NCT07888426
- Testing
- Nano-tocotrienols
- Where
- Malaysia
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Diabetes (DM)
Randomized Trial of the RIGHTEST iFree 2 CGM System for Glycemic Control in Adults With Diabetes Mellitus
The goal of this clinical trial is to find out whether using a real-time continuous glucose monitoring (CGM) system can improve daily blood sugar control compared with usual self-monitoring of blood glucose (SMBG; finger-stick…
- Trial name
- NCT07889375
- Testing
- Continuous Glucose Monitoring (CGM), Self-monitoring of blood glucose (SMBG)
- Where
- Taiwan
- Volunteers
- 324 people
- Sponsor
- Bionime Corporation
Hypertension (HTN), Diabetes (DM)
Team-Based Shared Decision-Making Program in Cardiovascular-Kidney-Metabolic Health (Healthy Heart - CKM)
The investigators are proposing a new team-based shared decision-making (SDM) program. The goal of this study is to see whether this program is practical and whether it may help adults with cardiometabolic risk factors and…
- Conditions
- Hypertension (HTN), Diabetes (DM), Hyperlipidaemia, Kidney Disease
- Trial name
- SDM in CKM (NCT07662616)
- Testing
- Team-based shared decision-making
- Volunteers
- 94 people
- Sponsor
- Johns Hopkins University
Diabetes (DM)
Adaptation, Implementation, and Validation of an Innovative eHealth System for the Self-management, Monitoring, and Specialized Remote Medical Care of Patients With Diabetes in the Municipalities of Palermo (Huila) and Suárez (Cauca).
The study corresponds to a controlled, randomized, open-label clinical experiment approved by the Ethics Committee of Universidad Antonio Nariño, with the participation of clinical scientific personnel and technical support from…
- Trial name
- NCT07849725
- Testing
- mHealth, Glucometry
- Where
- 2 sites in Colombia
- Volunteers
- 200 people
- Sponsor
- Universidad Antonio Nariño
Diabetes (DM), Type 2 Diabetes
Real-world Canadian Retrospective Study Evaluating Longitudinal Semaglutide Use on Cardio-Kidney-Metabolic Outcomes
The goal of this study is to better understand the real-world effectiveness of semaglutide use on cardio-kidney-metabolic outcomes among adults with T2D and adults with obesity (without diabetes mellitus).
- Conditions
- Diabetes (DM), Type 2 Diabetes, Obesity (Disorder)
- Trial name
- SEMA-CKM (NCT07424430)
- Testing
- Semaglutide (SEMA)
- Where
- Canada
- Volunteers
- 3,392 people
- Sponsor
- LMC Diabetes & Endocrinology Ltd.
Type 2 Diabetes Mellitus (DM)
A Study of VCT220 Tablets in Adults With Type 2 Diabetes and Inadequate Blood Glucose Control
This study will evaluate whether VCT220 tablets improve blood glucose control in adults with type 2 diabetes whose blood glucose remains inadequately controlled with lifestyle intervention alone, metformin alone, or metformin…
- Trial name
- VICTOR-DM (NCT07872436)
- Testing
- VCT220 tablets
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Vincentage Pharma Co., Ltd
Insulin Dependent Diabetes, Diabetes (DM)
Integrating New Skills Into Diabetes Education With CGM
This study is designed to test the preliminary efficacy of a three-stage continuous glucose monitor (CGM) integration program for older adults who are taking insulin.
- Conditions
- Insulin Dependent Diabetes, Diabetes (DM), Diabetes (Insulin-requiring, Type 1 or Type 2), Diabetes Education
- Trial name
- INSIDE-CGM (NCT07463209)
- Testing
- Three-stage CGM integration program, One-time clinic-based CGM training, Self-directed CGM training
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- University of North Carolina, Chapel Hill
Diabetes (DM)
Awareness of Bidirectional Relation of Diabetes Mellitus and Periodontal Health
The study will recruit patients having diabetes mellitus; where they will be asked to answer a questionnaire after obtaining an informed consent.
- Trial name
- NCT07858604
- Testing
- Questionnaire and Physical Exam
- Volunteers
- 323 people
- Sponsor
- Cairo University
Type 2 Diabetes Mellitus (DM), Accidental Falls
Effect of Otago vs. Sensorimotor Training on Balance and Fall Risk in People With Diabetes
The purpose of this study is to compare the effects of the Otago Exercise Program versus Sensorimotor Training on dynamic postural stability and risk of fall in patients with type 2 diabetes mellitus.
- Conditions
- Type 2 Diabetes Mellitus (DM), Accidental Falls, Postural Balance
- Trial name
- NCT07854496
- Testing
- Otago Exercise Program, Sensorimotor Training
- Volunteers
- 40 people
- Sponsor
- Cairo University
Chronic Kidney Disease(CKD), Type 2 DM
Implementation pRogram to Improve Screening and Management for CKD in Diabetes (Program 1) (IRIS-CKD)
IRIS-CKD is an implementation study to improve guideline-recommended screening of chronic kidney disease (CKD) in individuals with type 2 diabetes (T2D) in the United States.
- Conditions
- Chronic Kidney Disease(CKD), Type 2 DM, Type 2 Diabetes Mellitus (T2DM)
- Trial name
- IRIS-CKD (NCT06906627)
- Testing
- (IRIS-CKD Screening Program): Home Kit, (IRIS-CKD Screening Program): Standard Lab Order
- Where
- 7 sites in United States
- Volunteers
- 500 people
- Sponsor
- Duke University
Chronic Kidney Disease(CKD), Type 2 DM
Implementation pRogram to Improve Screening and Management for CKD in Diabetes (IRIS-CKD) (Program 2)
IRIS-CKD is a two-program implementation study to improve guideline-recommended screening and treatment of chronic kidney disease (CKD) in individuals with type 2 diabetes (T2D) in the United States.
- Conditions
- Chronic Kidney Disease(CKD), Type 2 DM, Type 2 Diabetes Mellitus (T2DM)
- Trial name
- IRIS-CKD (NCT06906640)
- Testing
- (IRIS-CKD Management Program): Education, (IRIS-CKD Management Program): GDMT
- Where
- 7 sites in United States
- Volunteers
- 212 people
- Sponsor
- Duke University
Diabetes (DM)
Role of Alpha-to-beta Cell Communication to Adapt Insulin Secretion to Insulin Resistance.
Glucagon secretion from α-cells has long been viewed as primarily a counterregulatory mechanism - e.g. an agent with a role to prevent blood sugar from decreasing to levels that compromise function.
- Trial name
- UPGRADE (NCT07224334)
- Testing
- Exendin-9 is a 30 amino acid peptide that is an established competitive antagonist of the GLP-1 receptor. Subjects will receive exendin-9 by intravenous infusion at a rate of 600 pmol/kg/min, Dexamethasone, Dextrose 20% solution
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- David D'Alessio, M.D.
Diabetic Neuropathy, Diabetes Mellitus (DM)
Effect of Golden Rice-Piper Crocatum Cookies on Neuropathy Prevention in Diabetes
Diabetes mellitus is a chronic disease that can cause many complications, one of the most common being diabetic neuropathy. This condition occurs due to long-term high blood sugar levels that damage the nerves.
- Conditions
- Diabetic Neuropathy, Diabetes Mellitus (DM), Functional Food, Nutritional Intervention
- Trial name
- GRIP-DN (NCT07272993)
- Testing
- Golden Rice Cookies With Piper Crocatum, Golden Rice Cookies Without Piper Crocatum
- Where
- Indonesia
- Volunteers
- 102 people
- Sponsor
- Hasanuddin University
Type 2 Diabetes Mellitus (DM), Gastric Ultrasound
Preoperative Gastric Volume and High-Risk Gastric Content in Patients With Type 2 Diabetes Mellitus
This prospective observational study will evaluate adult patients with type 2 diabetes mellitus who are scheduled for elective surgery.
- Trial name
- NCT07842757
- Testing
- Preoperative Gastric Ultrasonography, Capillary Fasting Blood Glucose Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Type 2 Diabetes Mellitus (DM)
Proteome-Wide Association and LLM-Based Prioritization of Type 2 Diabetes Protein Targets
Type 2 diabetes is a common condition in which the body has difficulty controlling blood sugar. This study will use existing genetic, protein, and health data from prior research studies to identify blood proteins that may play a…
- Trial name
- LAUNCH-T2D (NCT07832656)
- Volunteers
- 31,994 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Gut Microbiome, Gastrointestinal Microbiome
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.
- Conditions
- Gut Microbiome, Gastrointestinal Microbiome, Autism, Autism Spectrum Disorder
- Trial name
- NCT04031469
- Testing
- There is no intervention in this study
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- ProgenaBiome
Type 2 Diabetes Mellitus (DM)
Nature Image Exposure in Type 2 Diabetes
Type 2 diabetes often requires repeated procedures, including insulin self-injection and self-monitoring of blood glucose. These procedures may cause pain and lead to fear of self-injection and blood glucose testing, which may…
- Trial name
- NCT06787859
- Testing
- Nature Image Exposure
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Dicle University